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Published in Nature chemical biology (01.03.2014)
Published in Nature chemical biology (01.03.2014)
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Arresting Initiation of Hepatitis C Virus RNA Synthesis Using Heterocyclic Derivatives
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Published in The Journal of biological chemistry (09.05.2003)
Published in The Journal of biological chemistry (09.05.2003)
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Hydrazinonaphthalene and Azonaphthalene Thrombopoietin Mimics Are Nonpeptidyl Promoters of Megakaryocytopoiesis
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Published in Journal of medicinal chemistry (25.10.2001)
Published in Journal of medicinal chemistry (25.10.2001)
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Development of GSK's reagent guides ― embedding sustainability into reagent selection
ADAMS, Joseph P, ALDER, Catherine M, REDMAN, Anikó M, SHUSTER, Leanna E, SNEDDON, Helen F, WALKER, Matthew D, ANDREWS, Ian, BULLION, Ann M, CAMPBELL-CRAWFORD, Matthew, DARCY, Michael G, HAYLER, John D, HENDERSON, Richard K, OARE, Catriona A, PENDRAK, Israil
Published in Green chemistry : an international journal and green chemistry resource : GC (01.01.2013)
Published in Green chemistry : an international journal and green chemistry resource : GC (01.01.2013)
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3-(1,1-Dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, Potent Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase
Tedesco, Rosanna, Shaw, Antony N, Bambal, Ramesh, Chai, Deping, Concha, Nestor O, Darcy, Michael G, Dhanak, Dashyant, Fitch, Duke M, Gates, Adam, Gerhardt, Warren G, Halegoua, Dina L, Han, Chao, Hofmann, Glenn A, Johnston, Victor K, Kaura, Arun C, Liu, Nannan, Keenan, Richard M, Lin-Goerke, Juili, Sarisky, Robert T, Wiggall, Kenneth J, Zimmerman, Michael N, Duffy, Kevin J
Published in Journal of medicinal chemistry (09.02.2006)
Published in Journal of medicinal chemistry (09.02.2006)
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Substituted benzothiadizine inhibitors of Hepatitis C virus polymerase
Shaw, Antony N., Tedesco, Rosanna, Bambal, Ramesh, Chai, Deping, Concha, Nestor O., Darcy, Michael G., Dhanak, Dashyant, Duffy, Kevin J., Fitch, Duke M., Gates, Adam, Johnston, Victor K., Keenan, Richard M., Lin-Goerke, Juili, Liu, Nannan, Sarisky, Robert T., Wiggall, Kenneth J., Zimmerman, Michael N.
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Synthesis and biological activity of heteroaryl 3-(1,1-dioxo-2H-(1,2,4)-benzothiadizin-3-yl)-4-hydroxy-2(1H)-quinolinone derivatives as hepatitis C virus NS5B polymerase inhibitors
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Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295
Qian, Xiangping, McDonald, Andrew, Zhou, Han-Jie, Adams, Nicholas D, Parrish, Cynthia A, Duffy, Kevin J, Fitch, Duke M, Tedesco, Rosanna, Ashcraft, Luke W, Yao, Bing, Jiang, Hong, Huang, Jennifer K, Marin, Melchor V, Aroyan, Carrie E, Wang, Jianchao, Ahmed, Seyed, Burgess, Joelle L, Chaudhari, Amita M, Donatelli, Carla A, Darcy, Michael G, Ridgers, Lance H, Newlander, Ken A, Schmidt, Stanley J, Chai, Deping, Colón, Mariela, Zimmerman, Michael N, Lad, Latesh, Sakowicz, Roman, Schauer, Stephen, Belmont, Lisa, Baliga, Ramesh, Pierce, Daniel W, Finer, Jeffrey T, Wang, Zhengping, Morgan, Bradley P, Morgans, David J, Auger, Kurt R, Sung, Chiu-Mei, Carson, Jeff D, Luo, Lusong, Hugger, Erin D, Copeland, Robert A, Sutton, David, Elliott, John D, Jackson, Jeffrey R, Wood, Kenneth W, Dhanak, Dashyant, Bergnes, Gustave, Knight, Steven D
Published in ACS medicinal chemistry letters (08.04.2010)
Published in ACS medicinal chemistry letters (08.04.2010)
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Year of Publication 04.04.2024
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Year of Publication 04.04.2024
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Identification of Potent, Selective Non-peptide CC Chemokine Receptor-3 Antagonist That Inhibits Eotaxin-, Eotaxin-2-, and Monocyte Chemotactic Protein-4-induced Eosinophil Migration
White, John R., Lee, Judithann M., Dede, Kimberly, Imburgia, Christina S., Jurewicz, Anthony J., Chan, George, Fornwald, James A., Dhanak, Dashyant, Christmann, Lisa T., Darcy, Michael G., Widdowson, Katherine L., Foley, James J., Schmidt, Dulcie B., Sarau, Henry M.
Published in The Journal of biological chemistry (24.11.2000)
Published in The Journal of biological chemistry (24.11.2000)
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Abstract C62: Identification of GSK2126458, a highly potent inhibitor of phosphoinositide 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR)
Knight, Steven D., Adams, Nicholas D., Burgess, Joelle L., Chaudhari, Amita M., Darcy, Michael G., Donatelli, Carla A., Newlander, Ken A., Parrish, Cynthia A., Ridgers, Lance H., Sarpong, Martha A., Schmidt, Stanley J., Van Aller, Glenn, Carson, Jeff D., Elkins, Patricia A., Diamond, Melody, Gardiner, Christine M., Garver, Eric, Luo, Lusong, Raha, Kaushik, Sung, Chiu-Mei, Tummino, Peter J., Auger, Kurt R., Dhanak, Dashyant
Published in Molecular cancer therapeutics (10.12.2009)
Published in Molecular cancer therapeutics (10.12.2009)
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단백질 조절제로서 유용한 헤테로사이클릭 아미드
LI YUE, DODSON JASON W, RAMANJULU JOSHI M, CHARNLEY ADAM KENNETH, HUGHES TERRY V, NEVINS NEYSA, DARCY MICHAEL G, LIAN YIQIAN
Year of Publication 12.12.2018
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Year of Publication 12.12.2018
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Discovery of potent and selective phenylalanine derived CCR3 receptor antagonists. Part 2
Dhanak, Dashyant, Christmann, Lisa T, Darcy, Michael G, Keenan, Richard M, Knight, Steven D, Lee, Judithann, Ridgers, Lance H, Sarau, Henry M, Shah, Dinubhai H, White, John R, Zhang, Lily
Published in Bioorganic & medicinal chemistry letters (04.06.2001)
Published in Bioorganic & medicinal chemistry letters (04.06.2001)
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단백질 조정제로서 유용한 헤테로시클릭 아미드
LI YUE, RAMANJULU JOSHI M, CHARNLEY ADAM KENNETH, MEHLMANN JOHN F, HUGHES TERRY V, YE GUOSEN, KANG JIANXING, DARCY MICHAEL G, LEISTER LARA KATHRYN, DODSON JASON W, DONG XIAOYANG, ZHANG DAOHUA, NEVINS NEYSA, LIAN YIQIAN, ROMANO JOSEPH J, WANG GREN Z
Year of Publication 12.12.2018
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Year of Publication 12.12.2018
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HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS
LI YUE, RAMANJULU JOSHI M, CHARNLEY ADAM KENNETH, MEHLMANN JOHN F, HUGHES TERRY V, YE GUOSEN, KANG JIANXING, DARCY MICHAEL G, LEISTER LARA KATHRYN, DODSON JASON W, DONG XIAOYANG, ZHANG DAOHUA, NEVINS NEYSA, LIAN YIQIAN, ROMANO JOSEPH J, WANG GREN Z
Year of Publication 20.11.2018
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Year of Publication 20.11.2018
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Discovery of potent and selective phenylalanine derived CCR3 antagonists. Part 1
Dhanak, Dashyant, Christmann, Lisa T., Darcy, Michael G., Jurewicz, Anthony J., Keenan, Richard M., Lee, Judithann, Sarau, Henry M., Widdowson, Katherine L., White, John R.
Published in Bioorganic & medicinal chemistry letters (04.06.2001)
Published in Bioorganic & medicinal chemistry letters (04.06.2001)
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Metal mediated protease inhibition: design and synthesis of inhibitors of the human cytomegalovirus (hCMV) protease
Dhanak, Dashyant, Burton, George, Christmann, Lisa T, Darcy, Michael G, Elrod, Kyle C, Kaura, Arun, Keenan, Richard M, Link, John O, Peishoff, Catherine E, Shah, Dinubhai H
Published in Bioorganic & medicinal chemistry letters (16.10.2000)
Published in Bioorganic & medicinal chemistry letters (16.10.2000)
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Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin
Knight, Steven D, Adams, Nicholas D, Burgess, Joelle L, Chaudhari, Amita M, Darcy, Michael G, Donatelli, Carla A, Luengo, Juan I, Newlander, Ken A, Parrish, Cynthia A, Ridgers, Lance H, Sarpong, Martha A, Schmidt, Stanley J, Van Aller, Glenn S, Carson, Jeffrey D, Diamond, Melody A, Elkins, Patricia A, Gardiner, Christine M, Garver, Eric, Gilbert, Seth A, Gontarek, Richard R, Jackson, Jeffrey R, Kershner, Kevin L, Luo, Lusong, Raha, Kaushik, Sherk, Christian S, Sung, Chiu-Mei, Sutton, David, Tummino, Peter J, Wegrzyn, Ronald J, Auger, Kurt R, Dhanak, Dashyant
Published in ACS medicinal chemistry letters (08.04.2010)
Published in ACS medicinal chemistry letters (08.04.2010)
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Synthesis and antiviral activity of a novel class of HIV-1 protease inhibitors containing a heterocyclic P1′-P2′ amide bond isostere
Thompson, Scott K., Eppley, Alecia M., Frazee, James S., Darcy, Michael G., Lum, Robert T., Tomaszek, Thaddeus A., Ivanoff, Lucinda A., Morris, Jane F., Sternberg, Edmund J., Lambert, Dennis M., Fernandez, Annabellee V., Petteway, Stephen R., Meek, Thomas D, Metcalf, Brian W., Gleason, John G.
Published in Bioorganic & medicinal chemistry letters (01.10.1994)
Published in Bioorganic & medicinal chemistry letters (01.10.1994)
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Oxidation of amines with 2-sulfonyloxaziridines (Davis' reagents)
Zajac, Walter W, Walters, Thomas R, Darcy, Michael G
Published in Journal of organic chemistry (01.12.1988)
Published in Journal of organic chemistry (01.12.1988)
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