Metabolism and Pharmacokinetics of a Novel Src Kinase Inhibitor TG100435 ([7-(2,6-Dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine) and Its Active N-Oxide Metabolite TG100855 ([7-(2,6-Dichloro-phenyl)-5-methylbenzo[1,2,4]triazin-3-yl]-{4-[2-(1-oxy-pyrrolidin-1-yl)-ethoxy]-phenyl}-amine)
Hu, Steven X, Soll, Richard, Yee, Shiyin, Lohse, Daniel L, Kousba, Ahmed, Zeng, Binqi, Yu, Xiyun, McPherson, Andrew, Renick, Joel, Cao, Jianguo, Tabak, Arek, Hood, John, Doukas, John, Noronha, Glenn, Martin, Michael
Published in Drug metabolism and disposition (01.06.2007)
Published in Drug metabolism and disposition (01.06.2007)
Get full text
Journal Article
Metabolism and pharmacokinetics of a novel Src kinase inhibitor TG100435 ([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1 -yl-ethoxy)-phenyl]-amine) and its active N-oxide metabolite TG100855 ([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-{4-[2-(1 -oxy-pyrrolidin-1 -yl)-ethoxy]-phenyl}-amine)
HU, Steven X, SOIL, Richard, TABAK, Arek, HOOD, John, DOUKAS, John, NORONHA, Glenn, MARTIN, Michael, SHIYIN YEE, LOHSE, Daniel L, KOUSBA, Ahmed, BINQI ZENG, XIYUN YU, MCPHERSON, Andrew, RENICK, Joel, CAO, Jianguo
Published in Drug metabolism and disposition (01.06.2007)
Published in Drug metabolism and disposition (01.06.2007)
Get full text
Journal Article
Expression and characterization of catalytic and regulatory domains of rat tyrosine hydroxylase
Daubner, S. Colette, Lohse, Daniel L., Fitzpatrick, Paul F.
Published in Protein science (01.09.1993)
Published in Protein science (01.09.1993)
Get full text
Journal Article
Identification of the Intersubunit Binding Region in Rat Tyrosine Hydroxylase
Lohse, D.L., Fitzpatrick, P.F.
Published in Biochemical and biophysical research communications (30.12.1993)
Published in Biochemical and biophysical research communications (30.12.1993)
Get full text
Journal Article
BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES
CAO, JIANGUO, HOOD, JOHN, MC PHERSON, ANDREW, PATHAK, VED P, LOHSE, DANIEL, MAK, CHI CHING, NORONHA, GLENN, RENICK, JOEL, SOLL, RICHARD M, ZENG, BINQI
Year of Publication 14.08.2018
Get full text
Year of Publication 14.08.2018
Patent
BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES
CAO, JIANGUO, PATHAK, VED P, HOOD, JOHN D, MAK, CHI CHING, MCPHERSON, ANDREW, NORONHA, GLENN, RENICK, JOEL, SOLL, RICHARD M, LOHSE, DANIEL L, ZENG, BINQI
Year of Publication 27.06.2017
Get full text
Year of Publication 27.06.2017
Patent
BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES
NORONHA GLENN, SOLL RICHARD M, MC PHERSON ANDREW, CAO JIANGUO, ZENG BINQI, RENICK JOEL, HOOD JOHN, MAK CHI CHING, LOHSE DANIEL, PATHAK VED
Year of Publication 31.03.2017
Get full text
Year of Publication 31.03.2017
Patent
BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES
ZENG, Binqi, RENICK, Joel, HOOD, John, MAK, Chi, Ching, Noronha, Glenn, CAO, Jianguo, LOHSE, Daniel, MC PHERSON, Andrew, PATHAK, Ved, SOLL, Richard, M
Year of Publication 30.01.2017
Get full text
Year of Publication 30.01.2017
Patent
BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES
ZENG, Binqi, RENICK, Joel, HOOD, John, NORONHA, Glenn, MAK, Chi, Ching, CAO, Jianguo, LOHSE, Daniel, MC PHERSON, Andrew, PATHAK, Ved, SOLL, Richard, M
Year of Publication 10.11.2016
Get full text
Year of Publication 10.11.2016
Patent
BIARYLMETAPYRIMIDIN-KINASEINHIBITORER
ZENG, Binqi, MCPHERSON, Andrew, RENICK, Joel, HOOD, John, NORONHA, Glenn, MAK, Chi, Ching, CAO, Jianguo, LOHSE, Daniel, PATHAK, Ved, SOLL, Richard, M
Year of Publication 24.10.2016
Get full text
Year of Publication 24.10.2016
Patent
BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES
VED PATHAK, CHI CHING MAK, JOEL RENICK, DANIEL LOHSE, BINQI ZENG, ANDREW MC PHERSON, JOHN HOOD, JIANGUO CAO, RICHARD M. SOLL
Year of Publication 13.10.2016
Get full text
Year of Publication 13.10.2016
Patent
BI-ARYL META-PYRIMIDINE INHIBITORS OF KINASES
CAO, JIANGUO, HOOD, JOHN, MC PHERSON, ANDREW, SOLL, RICHARD, M, LOHSE, DANIEL, MAK, CHI, CHING, NORONHA, GLENN, RENICK, JOEL, PATHAK, VED, ZENG, BINQI
Year of Publication 13.07.2016
Get full text
Year of Publication 13.07.2016
Patent
Bi-aryl meta-pyrimidine inhibitors of kinases
MC PHERSON, ANDREW, CAO, JIANGUO, HOOD, JOHN, LOHSE, DANIEL, MAK, CHI CHING, NORONHA, GLENN, RENICK, JOEL, PATHAK, VED, SOLL, RICHARD M, ZENG, BINQI
Year of Publication 23.04.2015
Get full text
Year of Publication 23.04.2015
Patent
Bi-aryl meta-pyrimidine inhibitors of kinases
NORONHA GLENN, SOLL RICHARD M, PATHAK VED P, CAO JIANGUO, HOOD JOHN D, ZENG BINQI, LOHSE DANIEL L, RENICK JOEL, MCPHERSON ANDREW, MAK CHI CHING
Year of Publication 10.12.2013
Get full text
Year of Publication 10.12.2013
Patent