Recent progress in non-native nucleic acid modifications
McKenzie, Luke K, El-Khoury, Roberto, Thorpe, James D, Damha, Masad J, Hollenstein, Marcel
Published in Chemical Society reviews (26.04.2021)
Published in Chemical Society reviews (26.04.2021)
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Journal Article
i-Motif DNA: structural features and significance to cell biology
Abou Assi, Hala, Garavís, Miguel, González, Carlos, Damha, Masad J
Published in Nucleic acids research (19.09.2018)
Published in Nucleic acids research (19.09.2018)
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Journal Article
End-ligation can dramatically stabilize i-motifs at neutral pH
El-Khoury, Roberto, Damha, Masad J
Published in Chemical communications (Cambridge, England) (23.03.2023)
Published in Chemical communications (Cambridge, England) (23.03.2023)
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Journal Article
Mechanochemical Synthesis of Short DNA Fragments
Thorpe, James D., O'Reilly, Daniel, Friščić, Tomislav, Damha, Masad J.
Published in Chemistry : a European journal (22.07.2020)
Published in Chemistry : a European journal (22.07.2020)
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Journal Article
Telomeric i-motifs and C-strands inhibit parallel G-quadruplex extension by telomerase
El-Khoury, Roberto, Roman, Morgane, Assi, Hala Abou, Moye, Aaron L, Bryan, Tracy M, Damha, Masad J
Published in Nucleic acids research (27.10.2023)
Published in Nucleic acids research (27.10.2023)
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Journal Article
Accurately Modeling the Conformational Preferences of Nucleosides
Burai Patrascu, Mihai, Malek-Adamian, Elise, Damha, Masad J, Moitessier, Nicolas
Published in Journal of the American Chemical Society (04.10.2017)
Published in Journal of the American Chemical Society (04.10.2017)
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Journal Article
Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles
Ageely, Eman A., Chilamkurthy, Ramadevi, Jana, Sunit, Abdullahu, Leonora, O’Reilly, Daniel, Jensik, Philip J., Damha, Masad J., Gagnon, Keith T.
Published in Nature communications (15.11.2021)
Published in Nature communications (15.11.2021)
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Journal Article
Design and enhanced gene silencing activity of spherical 2′-fluoroarabinose nucleic acids (FANA-SNAs)
Fakih, Hassan H, Katolik, Adam, Malek-Adamian, Elise, Fakhoury, Johans J, Kaviani, Sepideh, Damha, Masad J, Sleiman, Hanadi F
Published in Chemical science (Cambridge) (04.03.2021)
Published in Chemical science (Cambridge) (04.03.2021)
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Journal Article
In-cell NMR suggests that DNA i-motif levels are strongly depleted in living human cells
Víšková, Pavlína, Ištvánková, Eva, Ryneš, Jan, Džatko, Šimon, Loja, Tomáš, Živković, Martina Lenarčič, Rigo, Riccardo, El-Khoury, Roberto, Serrano-Chacón, Israel, Damha, Masad J., González, Carlos, Mergny, Jean-Louis, Foldynová-Trantírková, Silvie, Trantírek, Lukáš
Published in Nature communications (05.03.2024)
Published in Nature communications (05.03.2024)
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Dual Mechanisms of Action of Self-Delivering, Anti-HIV-1 FANA Oligonucleotides as a Potential New Approach to HIV Therapy
Takahashi, Mayumi, Li, Haitang, Zhou, Jiehua, Chomchan, Pritsana, Aishwarya, Veenu, Damha, Masad J., Rossi, John J.
Published in Molecular therapy. Nucleic acids (06.09.2019)
Published in Molecular therapy. Nucleic acids (06.09.2019)
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Journal Article
The debranching enzyme Dbr1 regulates lariat turnover and intron splicing
Buerer, Luke, Clark, Nathaniel E., Welch, Anastasia, Duan, Chaorui, Taggart, Allison J., Townley, Brittany A., Wang, Jing, Soemedi, Rachel, Rong, Stephen, Lin, Chien-Ling, Zeng, Yi, Katolik, Adam, Staley, Jonathan P., Damha, Masad J., Mosammaparast, Nima, Fairbrother, William G.
Published in Nature communications (30.05.2024)
Published in Nature communications (30.05.2024)
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Journal Article
4′‑C‑Methoxy-2′-deoxy-2′-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing
Malek-Adamian, Elise, Guenther, Dale C, Matsuda, Shigeo, Martínez-Montero, Saúl, Zlatev, Ivan, Harp, Joel, Burai Patrascu, Mihai, Foster, Donald J, Fakhoury, Johans, Perkins, Lydia, Moitessier, Nicolas, Manoharan, Rajar M, Taneja, Nate, Bisbe, Anna, Charisse, Klaus, Maier, Martin, Rajeev, Kallanthottathil G, Egli, Martin, Manoharan, Muthiah, Damha, Masad J
Published in Journal of the American Chemical Society (18.10.2017)
Published in Journal of the American Chemical Society (18.10.2017)
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Journal Article
Locked 2′-Deoxy-2′,4′-Difluororibo Modified Nucleic Acids: Thermal Stability, Structural Studies, and siRNA Activity
Martínez-Montero, Saúl, Deleavey, Glen F, Martín-Pintado, Nerea, Fakhoury, Johans F, González, Carlos, Damha, Masad J
Published in ACS chemical biology (18.09.2015)
Published in ACS chemical biology (18.09.2015)
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Journal Article
Small Molecule‐Templated DNA Hydrogel with Record Stiffness Integrates and Releases DNA Nanostructures and Gene Silencing Nucleic Acids
Lachance‐Brais, Christophe, Rammal, Mostafa, Asohan, Jathavan, Katolik, Adam, Luo, Xin, Saliba, Daniel, Jonderian, Antranik, Damha, Masad J., Harrington, Matthew J., Sleiman, Hanadi F.
Published in Advanced science (01.04.2023)
Published in Advanced science (01.04.2023)
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Journal Article
A mechanism for the extension and unfolding of parallel telomeric G-quadruplexes by human telomerase at single-molecule resolution
Paudel, Bishnu P, Moye, Aaron Lavel, Abou Assi, Hala, El-Khoury, Roberto, Cohen, Scott B, Holien, Jessica K, Birrento, Monica L, Samosorn, Siritron, Intharapichai, Kamthorn, Tomlinson, Christopher G, Teulade-Fichou, Marie-Paule, González, Carlos, Beck, Jennifer L, Damha, Masad J, van Oijen, Antoine M, Bryan, Tracy M
Published in eLife (29.07.2020)
Published in eLife (29.07.2020)
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Journal Article
Synergistic effects between analogs of DNA and RNA improve the potency of siRNA-mediated gene silencing
Deleavey, Glen F, Watts, Jonathan K, Alain, Tommy, Robert, Francis, Kalota, Anna, Aishwarya, Veenu, Pelletier, Jerry, Gewirtz, Alan M, Sonenberg, Nahum, Damha, Masad J
Published in Nucleic acids research (01.07.2010)
Published in Nucleic acids research (01.07.2010)
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Journal Article
Synthesis and Properties of 2′-Deoxy-2′,4′-difluoroarabinose-Modified Nucleic Acids
Martínez-Montero, Saúl, Deleavey, Glen F, Dierker-Viik, Arden, Lindovska, Petra, Ilina, Tatiana, Portella, Guillem, Orozco, Modesto, Parniak, Michael A, González, Carlos, Damha, Masad J
Published in Journal of organic chemistry (20.03.2015)
Published in Journal of organic chemistry (20.03.2015)
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