Heavy-chain antibody targeting of CD38 NAD + hydrolase ectoenzyme to prevent fibrosis in multiple organs
Shi, Bo, Amin, Asif, Dalvi, Pranjali, Wang, Wenxia, Lukacs, Nicholas, Kai, Li, Cheresh, Paul, Peclat, Thais R, Chini, Claudia C, Chini, Eduardo N, van Schooten, Wim, Varga, John
Published in Scientific reports (12.12.2023)
Published in Scientific reports (12.12.2023)
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Journal Article
Enhanced autophagy in pulmonary endothelial cells on exposure to HIV-Tat and morphine: Role in HIV-related pulmonary arterial hypertension
Dalvi, Pranjali, Sharma, Himanshu, Chinnappan, Mahendran, Sanderson, Miles, Allen, Julie, Zeng, Ruoxi, Choi, Augustine, O'Brien-Ladner, Amy, Dhillon, Navneet K.
Published in Autophagy (01.12.2016)
Published in Autophagy (01.12.2016)
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Journal Article
Network of MicroRNAs Mediate Translational Repression of Bone Morphogenetic Protein Receptor‐2: Involvement in HIV‐Associated Pulmonary Vascular Remodeling
Chinnappan, Mahendran, Mohan, Aradhana, Agarwal, Stuti, Dalvi, Pranjali, Dhillon, Navneet K.
Published in Journal of the American Heart Association (06.03.2018)
Published in Journal of the American Heart Association (06.03.2018)
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Journal Article
HIV-1/cocaine induced oxidative stress disrupts tight junction protein-1 in human pulmonary microvascular endothelial cells: role of Ras/ERK1/2 pathway
Dalvi, Pranjali, Wang, Kun, Mermis, Joel, Zeng, Ruoxi, Sanderson, Miles, Johnson, Sara, Dai, Yuqiao, Sharma, Garima, Ladner, Amy O'Brien, Dhillon, Navneet K
Published in PloS one (07.01.2014)
Published in PloS one (07.01.2014)
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Journal Article
Attenuating CD3 affinity in a PSMAxCD3 bispecific antibody enables killing of prostate tumor cells with reduced cytokine release
Dang, Kevin, Castello, Giulia, Clarke, Starlynn C, Li, Yuping, Balasubramani, Aarti, Boudreau, Andrew, Davison, Laura, Harris, Katherine E, Pham, Duy, Sankaran, Preethi, Ugamraj, Harshad S, Deng, Rong, Kwek, Serena, Starzinski, Alec, Iyer, Suhasini, van Schooten, Wim, Schellenberger, Ute, Sun, Wenchao, Trinklein, Nathan D, Buelow, Roland, Buelow, Ben, Fong, Lawrence, Dalvi, Pranjali
Published in Journal for immunotherapy of cancer (01.06.2021)
Published in Journal for immunotherapy of cancer (01.06.2021)
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Journal Article
TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity
Ugamraj, Harshad S., Dang, Kevin, Ouisse, Laure-Hélène, Buelow, Benjamin, Chini, Eduardo N., Castello, Giulia, Allison, James, Clarke, Starlynn C, Davison, Laura M., Buelow, Roland, Deng, Rong, Iyer, Suhasini, Schellenberger, Ute, Manika, Sankar N., Bijpuria, Shipra, Musnier, Astrid, Poupon, Anne, Cuturi, Maria Cristina, van Schooten, Wim, Dalvi, Pranjali
Published in mAbs (22.07.2022)
Published in mAbs (22.07.2022)
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Journal Article
A T-cell engaging bispecific antibody with a tumor-selective bivalent folate receptor alpha binding arm for the treatment of ovarian cancer
Avanzino, Brian C., Prabhakar, Kirthana, Dalvi, Pranjali, Hartstein, Sharon, Kehm, Hannes, Balasubramani, Aarti, Boudreau, Andrew A., Buelow, Ben, Chang, Karen, Davison, Laura M., Iyer, Suhasini, Kalwit, Vidyut, Lewis Wilson, Kristin, Malik-Chaudhry, Harbani K., Pierson, Will, Pineda, Geovanni, Rangaswamy, Udaya S., Saiganesh, Sowmya, Schellenberger, Ute, Ugamraj, Harshad S., Yabut, Rodolfovan D., Buelow, Roland, Chapman, Jocelyn, Trinklein, Nathan D., Harris, Katherine E.
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
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Journal Article
Functional characterization and molecular expression of large neutral amino acid transporter (LAT1) in human prostate cancer cells
Patel, Mitesh, Dalvi, Pranjali, Gokulgandhi, Mitan, Kesh, Susamita, Kohli, Tanvi, Pal, Dhananjay, Mitra, Ashim K.
Published in International journal of pharmaceutics (25.02.2013)
Published in International journal of pharmaceutics (25.02.2013)
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Journal Article
Ligand-Independent Activation of Platelet-Derived Growth Factor Receptor β during Human Immunodeficiency Virus-Transactivator of Transcription and Cocaine-Mediated Smooth Muscle Hyperplasia
Dalvi, Pranjali N, Gupta, Vijayalaxmi G, Griffin, Brooke R, O'Brien-Ladner, Amy, Dhillon, Navneet K
Published in American journal of respiratory cell and molecular biology (01.09.2015)
Published in American journal of respiratory cell and molecular biology (01.09.2015)
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Journal Article
Macrophage‐derived extracellular vesicles mediate smooth muscle hyperplasia: role of altered miRNA cargo in response to HIV infection and substance abuse
Sharma, Himanshu, Chinnappan, Mahendran, Agarwal, Stuti, Dalvi, Pranjali, Gunewardena, Sumedha, O'Brien-Ladner, Amy, Dhillon, Navneet K.
Published in The FASEB journal (01.09.2018)
Published in The FASEB journal (01.09.2018)
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Journal Article
Downregulation of Bone Morphogenetic Protein Receptor Axis During HIV-1 and Cocaine-Mediated Pulmonary Smooth Muscle Hyperplasia: Implications for HIV-Related Pulmonary Arterial Hypertension
Dalvi, Pranjali, O’Brien-Ladner, Amy, Dhillon, Navneet K
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2013)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2013)
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Journal Article
TNB585.001: A multicenter, phase 1, open-label, dose-escalation and expansion study of tnb-585, a bispecific T-cell engager targeting PSMA in subjects with metastatic castrate resistant prostate cancer
Buelow, Ben, Dalvi, Pranjali, Dang, Kevin, Patel, Ashwin, Johal, Kiran, Pham, Duy, Panchal, Shailee, Liu, Yvonne, Fong, Lawrence, Sartor, A. Oliver, McKean, Meredith, Schellenberger, Ute, Iyer, Suhasini
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Journal Article
Ecto-CD38-NADase inhibition modulates cardiac metabolism and protects mice against doxorubicin-induced cardiotoxicity
Peclat, Thais R, Agorrody, Guillermo, Colman, Laura, Kashyap, Sonu, Zeidler, Julianna D, Chini, Claudia C S, Warner, Gina M, Thompson, Katie L, Dalvi, Pranjali, Beckedorff, Felipe, Ebtehaj, Sanam, Herrmann, Joerg, van Schooten, Wim, Chini, Eduardo Nunes
Published in Cardiovascular research (14.03.2024)
Published in Cardiovascular research (14.03.2024)
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Journal Article
Drug abuse and HIV-related pulmonary hypertension: double hit injury
Harter, Zachery J, Agarwal, Stuti, Dalvi, Pranjali, Voelkel, Norbert F, Dhillon, Navneet K
Published in AIDS (London) (28.11.2018)
Published in AIDS (London) (28.11.2018)
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Journal Article
Effect of modulation of CD3 binding in a PSMAxCD3 T-cell engaging bispecific antibody on maintenance of efficient tumor cell kill and cytokine release
Buelow, Ben, Dang, Kevin, Dalvi, Pranjali, Li, Yuping, Cheung, Alexander, Rancan, Chiara, Sankaran, Preethi, Pham, Duy, Harris, Katherine, Davison, Laura, Balasubramani, Aarti, Clarke, Starlynn, Starzinski, Alec, Fong, Lawrence, Iyer, Suhasini
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Hyperactive TGF-β Signaling in Smooth Muscle Cells Exposed to HIV-protein(s) and Cocaine: Role in Pulmonary Vasculopathy
Dalvi, Pranjali, Sharma, Himanshu, Konstantinova, Tomara, Sanderson, Miles, Brien-Ladner, Amy O', Dhillon, Navneet K
Published in Scientific reports (05.09.2017)
Published in Scientific reports (05.09.2017)
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Journal Article
Effect of Cocaine on Pulmonary Vascular Remodeling and Hemodynamics in Human Immunodeficiency Virus-Transgenic Rats
Dalvi, Pranjali, Spikes, Leslie, Allen, Julie, Gupta, Vijayalaxmi G, Sharma, Himanshu, Gillcrist, Marion, Montes de Oca, Jamison, O'Brien-Ladner, Amy, Dhillon, Navneet K
Published in American journal of respiratory cell and molecular biology (01.08.2016)
Published in American journal of respiratory cell and molecular biology (01.08.2016)
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Journal Article