SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
Ogando, Natacha S, Dalebout, Tim J, Zevenhoven-Dobbe, Jessika C, Limpens, Ronald W A L, van der Meer, Yvonne, Caly, Leon, Druce, Julian, de Vries, Jutte J C, Kikkert, Marjolein, Bárcena, Montserrat, Sidorov, Igor, Snijder, Eric J
Published in Journal of general virology (01.09.2020)
Published in Journal of general virology (01.09.2020)
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Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses
Rabouw, Huib H, Langereis, Martijn A, Knaap, Robert C M, Dalebout, Tim J, Canton, Javier, Sola, Isabel, Enjuanes, Luis, Bredenbeek, Peter J, Kikkert, Marjolein, de Groot, Raoul J, van Kuppeveld, Frank J M
Published in PLoS pathogens (01.10.2016)
Published in PLoS pathogens (01.10.2016)
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Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses
Bos, Rinke, Rutten, Lucy, van der Lubbe, Joan E. M., Bakkers, Mark J. G., Hardenberg, Gijs, Wegmann, Frank, Zuijdgeest, David, de Wilde, Adriaan H., Koornneef, Annemart, Verwilligen, Annemiek, van Manen, Danielle, Kwaks, Ted, Vogels, Ronald, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., Li, Zhenfeng, Barouch, Dan H., Vellinga, Jort, Langedijk, Johannes P. M., Zahn, Roland C., Custers, Jerome, Schuitemaker, Hanneke
Published in npj vaccines (28.09.2020)
Published in npj vaccines (28.09.2020)
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Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression
Bailey-Elkin, Ben A., Knaap, Robert C.M., Johnson, Garrett G., Dalebout, Tim J., Ninaber, Dennis K., van Kasteren, Puck B., Bredenbeek, Peter J., Snijder, Eric J., Kikkert, Marjolein, Mark, Brian L.
Published in The Journal of biological chemistry (12.12.2014)
Published in The Journal of biological chemistry (12.12.2014)
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Engineering potent live attenuated coronavirus vaccines by targeted inactivation of the immune evasive viral deubiquitinase
Myeni, Sebenzile K., Bredenbeek, Peter J., Knaap, Robert C. M., Dalebout, Tim J., Morales, Shessy Torres, Sidorov, Igor A., Linger, Marissa E., Oreshkova, Nadia, van Zanen-Gerhardt, Sophie, Zander, Serge A. L., Enjuanes, Luis, Sola, Isabel, Snijder, Eric J., Kikkert, Marjolein
Published in Nature communications (28.02.2023)
Published in Nature communications (28.02.2023)
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Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants
Zhang, Wei, Bailey-Elkin, Ben A, Knaap, Robert C M, Khare, Baldeep, Dalebout, Tim J, Johnson, Garrett G, van Kasteren, Puck B, McLeish, Nigel J, Gu, Jun, He, Wenguang, Kikkert, Marjolein, Mark, Brian L, Sidhu, Sachdev S
Published in PLoS pathogens (01.05.2017)
Published in PLoS pathogens (01.05.2017)
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A Yellow Fever 17D Virus Replicon-Based Vaccine Platform for Emerging Coronaviruses
Oreshkova, Nadia, Myeni, Sebenzile K, Mishra, Niraj, Albulescu, Irina C, Dalebout, Tim J, Snijder, Eric J, Bredenbeek, Peter J, Dallmeier, Kai, Kikkert, Marjolein
Published in Vaccines (Basel) (16.12.2021)
Published in Vaccines (Basel) (16.12.2021)
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Yellow fever 17D-vectored vaccines expressing Lassa virus GP1 and GP2 glycoproteins provide protection against fatal disease in guinea pigs
Jiang, Xiaohong, Dalebout, Tim J, Bredenbeek, Peter J, Carrion, Ricardo, Brasky, Kathleen, Patterson, Jean, Goicochea, Marco, Bryant, Joseph, Salvato, Maria S, Lukashevich, Igor S
Published in Vaccine (01.02.2011)
Published in Vaccine (01.02.2011)
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Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease
van der Lubbe, Joan E. M., Rosendahl Huber, Sietske K., Vijayan, Aneesh, Dekking, Liesbeth, van Huizen, Ella, Vreugdenhil, Jessica, Choi, Ying, Baert, Miranda R. M., Feddes-de Boer, Karin, Izquierdo Gil, Ana, van Heerden, Marjolein, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., de Waal, Leon, Stittelaar, Koert J., Tolboom, Jeroen T. B. M., Serroyen, Jan, Muchene, Leacky, van der Fits, Leslie, Rutten, Lucy, Langedijk, Johannes P. M., Barouch, Dan H., Schuitemaker, Hanneke, Zahn, Roland C., Wegmann, Frank
Published in npj vaccines (19.03.2021)
Published in npj vaccines (19.03.2021)
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Conservation of the pentanucleotide motif at the top of the yellow fever virus 17D 3' stem-loop structure is not required for replication
Silva, Patricia A. G. C, Molenkamp, Richard, Dalebout, Tim J, Charlier, Nathalie, Neyts, Johan H, Spaan, Willy J. M, Bredenbeek, Peter J
Published in Journal of general virology (01.06.2007)
Published in Journal of general virology (01.06.2007)
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Evolution of naturally occurring 5' non-translated region variants of hepatitis C virus genotype 1b in selectable replicons
van Leeuwen, Hans C, Reusken, Chantal B. E. M, Roeten, Marko, Dalebout, Tim J, Riezu-Boj, Jose Ignacio, Ruiz, Juan, Spaan, Willy J. M
Published in Journal of general virology (01.07.2004)
Published in Journal of general virology (01.07.2004)
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Immunogenicity and efficacy of one and two doses of Ad26.COV2.S COVID vaccine in adult and aged NHP
Solforosi, Laura, Kuipers, Harmjan, Jongeneelen, Mandy, Rosendahl Huber, Sietske K, van der Lubbe, Joan E M, Dekking, Liesbeth, Czapska-Casey, Dominika N, Izquierdo Gil, Ana, Baert, Miranda R M, Drijver, Joke, Vaneman, Joost, van Huizen, Ella, Choi, Ying, Vreugdenhil, Jessica, Kroos, Sanne, de Wilde, Adriaan H, Kourkouta, Eleni, Custers, Jerome, van der Vlugt, Remko, Veldman, Daniel, Huizingh, Jeroen, Kaszas, Krisztian, Dalebout, Tim J, Myeni, Sebenzile K, Kikkert, Marjolein, Snijder, Eric J, Barouch, Dan H, Böszörményi, Kinga P, Stammes, Marieke A, Kondova, Ivanela, Verschoor, Ernst J, Verstrepen, Babs E, Koopman, Gerrit, Mooij, Petra, Bogers, Willy M J M, van Heerden, Marjolein, Muchene, Leacky, Tolboom, Jeroen T B M, Roozendaal, Ramon, Brandenburg, Boerries, Schuitemaker, Hanneke, Wegmann, Frank, Zahn, Roland C
Published in The Journal of experimental medicine (05.07.2021)
Published in The Journal of experimental medicine (05.07.2021)
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Conservation of the pentanucleotide motif at the top of the yellow fever virus 17D 3′ stem–loop structure is not required for replication
Silva, Patrícia A. G. C., Molenkamp, Richard, Dalebout, Tim J., Charlier, Nathalie, Neyts, Johan H., Spaan, Willy J. M., Bredenbeek, Peter J.
Published in Journal of general virology (01.08.2007)
Published in Journal of general virology (01.08.2007)
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Analysis of hepatitis C virus/classical swine fever virus chimeric 5′NTRs: sequences within the hepatitis C virus IRES are required for viral RNA replication
Reusken, Chantal B. E. M., Dalebout, Tim J., Eerligh, Peter, Bredenbeek, Peter J., Spaan, Willy J. M.
Published in Journal of general virology (01.07.2003)
Published in Journal of general virology (01.07.2003)
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Journal Article
Analysis of hepatitis C virus/classical swine fever virus chimeric 5'NTRs: sequences within the hepatitis C virus IRES are required for viral RNA replication
Reusken, Chantal B. E. M, Dalebout, Tim J, Eerligh, Peter, Bredenbeek, Peter J, Spaan, Willy J. M
Published in Journal of general virology (01.07.2003)
Published in Journal of general virology (01.07.2003)
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Ad26-vector based COVID-19 vaccine encoding a prefusion stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses
Bos, Rinke, Rutten, Lucy, Joan Em Van Der Lubbe, Bakkers, Mark Jg, Hardenberg, Gijs, Wegmann, Frank, Zuijdgeest, David, De Wilde, Adriaan H, Koornneef, Annemart, Verwilligen, Annemiek, Danielle Van Manen, Kwaks, Ted, Vogels, Ronald, Dalebout, Tim J, Myeni, Sebenzile K, Kikkert, Marjolein, Snijder, Eric J, Li, Zhenfeng, Barouch, Dan H, Vellinga Jort, Johannes Pm Langedijk, Zahn, Roland C, Custers, Jerome, Schuitemaker, Hanneke
Published in bioRxiv (30.07.2020)
Published in bioRxiv (30.07.2020)
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Ad26.COV2.S-elicited immunity protects against G614 spike variant SARS-CoV-2 infection in Syrian hamsters and does not enhance respiratory disease in challenged animals with breakthrough infection after sub-optimal vaccine dosing
Joan Em Van Der Lubbe, Rosendahl Huber, Sietske K, Vijayan, Aneesh, Dekking, Liesbeth, Ella Van Huizen, Vreugdenhil, Jessica, Choi, Ying, Baert, Miranda Rm, Feddes-De Boer, Karin, Ana Izquierdo Gil, Marjolein Van Heerden, Dalebout, Tim J, Myeni, Sebenzile K, Kikkert, Marjolein, Snijder, Eric J, Leon De Waal, Stittelaar, Koert J, Tolboom, Jeroen Tbm, Serroyen, Jan, Muchene, Leacky, Van Der Fits, Leslie, Rutten, Lucy, Johannes Pm Langedijk, Barouch, Dan H, Schuitemaker, Hanneke, Zahn, Roland C, Wegmann, Frank
Published in bioRxiv (08.01.2021)
Published in bioRxiv (08.01.2021)
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Immunogenicity and protective efficacy of one- and two-dose regimens of the Ad26.COV2.S COVID-19 vaccine candidate in adult and aged rhesus macaques
Solforosi, Laura, Kuipers, Harmjan, Rosendahl Huber, Sietske K, Joan Em Van Der Lubbe, Dekking, Liesbeth, Czapska-Casey, Dominika N, Ana Izquierdo Gil, Baert, Miranda Rm, Drijver, Joke, Vaneman, Joost, Ella Van Huizen, Choi, Ying, Vreugdenhil, Jessica, Kroos, Sanne, De Wilde, Adriaan H, Kourkouta, Eleni, Custers, Jerome, Dalebout, Tim J, Myeni, Sebenzile K, Kikkert, Marjolein, Snijder, Eric J, Barouch, Dan H, Böszörményi, Kinga P, Stammes, Marieke A, Kondova, Ivanela, Verschoor, Ernst J, Verstrepen, Babs E, Koopman, Gerrit, Mooij, Petra, Bogers, Willy Mjm, Marjolein Van Heerden, Muchene, Leacky, Tolboom, Jeroen Tbm, Roozendaal, Ramon, Schuitemaker, Hanneke, Wegmann, Frank, Zahn, Roland C
Published in bioRxiv (04.01.2021)
Published in bioRxiv (04.01.2021)
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