The A to Z of modulated cell patterning by mammalian thioredoxin reductases
Dagnell, Markus, Schmidt, Edward E., Arnér, Elias S.J.
Published in Free radical biology & medicine (01.02.2018)
Published in Free radical biology & medicine (01.02.2018)
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Journal Article
Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades
Dagnell, Markus, Cheng, Qing, Rizvi, Syed Husain Mustafa, Pace, Paul E., Boivin, Benoit, Winterbourn, Christine C., Arnér, Elias S.J.
Published in The Journal of biological chemistry (16.08.2019)
Published in The Journal of biological chemistry (16.08.2019)
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Journal Article
Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation
James, Jaime, Chen, Yifei, Hernandez, Clara M, Forster, Florian, Dagnell, Markus, Cheng, Qing, Saei, Amir A, Gharibi, Hassan, Lahore, Gonzalo Fernandez, Åstrand, Annika, Malhotra, Rajneesh, Malissen, Bernard, Zubarev, Roman A, Arnér, Elias S J, Holmdahl, Rikard
Published in eLife (19.05.2022)
Published in eLife (19.05.2022)
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Journal Article
Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure
Dagnell, Markus, Pace, Paul E., Cheng, Qing, Frijhoff, Jeroen, Östman, Arne, Arnér, Elias S.J., Hampton, Mark B., Winterbourn, Christine C.
Published in The Journal of biological chemistry (01.09.2017)
Published in The Journal of biological chemistry (01.09.2017)
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Journal Article
Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-β receptor tyrosine kinase signaling
Dagnell, Markus, Frijhoff, Jeroen, Pader, Irina, Augsten, Martin, Boivin, Benoit, Xu, Jianqiang, Mandal, Pankaj K., Tonks, Nicholas K., Hellberg, Carina, Conrad, Marcus, Arnér, Elias S. J., Östman, Arne
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2013)
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Journal Article
Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis
Hellfritsch, Juliane, Kirsch, Julian, Schneider, Manuela, Fluege, Tamara, Wortmann, Markus, Frijhoff, Jeroen, Dagnell, Markus, Fey, Theres, Esposito, Irene, Kölle, Pirkko, Pogoda, Kristin, Angeli, José Pedro Friedmann, Ingold, Irina, Kuhlencordt, Peter, Östman, Arne, Pohl, Ulrich, Conrad, Marcus, Beck, Heike
Published in Antioxidants & redox signaling (10.04.2015)
Published in Antioxidants & redox signaling (10.04.2015)
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Journal Article
12/15-lipoxygenase–derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases
Conrad, Marcus, Sandin, Åsa, Förster, Heidi, Seiler, Alexander, Frijhoff, Jeroen, Dagnell, Markus, Bornkamm, Georg W., Rådmark, Olof, van Huijsduijnen, Rob Hooft, Aspenström, Pontus, Böhmer, Frank, Östman, Arne, Schlessinger, Joseph
Published in Proceedings of the National Academy of Sciences - PNAS (07.09.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (07.09.2010)
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Journal Article
Hypoxia enhances platelet-derived growth factor signaling in the pulmonary vasculature by down-regulation of protein tyrosine phosphatases
ten Freyhaus, Henrik, Dagnell, Markus, Leuchs, Maike, Vantler, Marius, Berghausen, Eva M, Caglayan, Evren, Weissmann, Norbert, Dahal, Bhola K, Schermuly, Ralph T, Ostman, Arne, Kappert, Kai, Rosenkranz, Stephan
Published in American journal of respiratory and critical care medicine (15.04.2011)
Published in American journal of respiratory and critical care medicine (15.04.2011)
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Journal Article
Hypoxia followed by re-oxygenation induces oxidation of tyrosine phosphatases
Sandin, Åsa, Dagnell, Markus, Gonon, Adrian, Pernow, John, Stangl, Verena, Aspenström, Pontus, Kappert, Kai, Östman, Arne
Published in Cellular signalling (01.05.2011)
Published in Cellular signalling (01.05.2011)
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Journal Article
Regulation of protein tyrosine phosphatase oxidation in cell adhesion and migration
Frijhoff, Jeroen, Dagnell, Markus, Godfrey, Rinesh, Ostman, Arne
Published in Antioxidants & redox signaling (01.05.2014)
Published in Antioxidants & redox signaling (01.05.2014)
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Journal Article
OP-22 - Bicarbonate is required for hydrogen peroxide-dependent inactivation of PTP1B in presence of the Trx system and peroxiredoxin
Dagnell, Markus, Cheng, Qing, Pace, Paul E., Hampton, Mark B., Winterbourn, Christine C., Arnér, Elias S.J.
Published in Free radical biology & medicine (20.05.2018)
Published in Free radical biology & medicine (20.05.2018)
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Journal Article
The mitochondrial reactive oxygen species regulator p66Shc controls PDGF-induced signaling and migration through protein tyrosine phosphatase oxidation
Frijhoff, Jeroen, Dagnell, Markus, Augsten, Martin, Beltrami, Elena, Giorgio, Marco, Östman, Arne
Published in Free radical biology & medicine (01.03.2014)
Published in Free radical biology & medicine (01.03.2014)
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Journal Article
84 - Thioredoxin Reductase 1 Directly Protects Protein Tyrosine Phosphatase 1B from Inactivation by H2O2
Dagnell, Markus, Pace, Paul, Cheng, Qing, Frijhoff, Jeroen, Östman, Arne, Arnér, Elias, Hampton, Mark, Winterbourn, Christine
Published in Free radical biology & medicine (01.11.2016)
Published in Free radical biology & medicine (01.11.2016)
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Journal Article
Thioredoxin Reductase 1 Directly Protects Protein Tyrosine Phosphatase 1B from Inactivation by H2O2
Dagnell, Markus, Pace, Paul, Cheng, Qing, Frijhoff, Jeroen, Östman, Arne, Arnér, Elias, Hampton, Mark, Winterbourn, Christine
Published in Free radical biology & medicine (01.11.2016)
Published in Free radical biology & medicine (01.11.2016)
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Journal Article
FBXW7/hCDC4 is a general tumor suppressor in human cancer
AKHOONDI, Shahab, DAHUI SUN, MUELLER-HOLZNER, Elisabeth, CORCORAN, Martin, DAGNELL, Markus, SEPIDEH ZABIHI NEJAD, BABAK NOORI NAYER, MOHAMMAD REZA ZALI, HANSSON, Johan, EGYHAZI, Susanne, PETERSSON, Fredrik, SANGFELT, Per, VON DER LEHR, Natalie, NORDGREN, Hans, GRANDER, Dan, REED, Steven I, WIDSCHWENDTER, Martin, SANGFELT, Olle, SPRUCK, Charles, APOSTOLIDOU, Sophia, KLOTZ, Kathleen, MALJUKOVA, Alena, CEPEDA, Diana, FIEGL, Heidi, DOFOU, Dimitra, MARTH, Christian
Published in Cancer research (Chicago, Ill.) (01.10.2007)
Published in Cancer research (Chicago, Ill.) (01.10.2007)
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Journal Article
Abstract 17649: Inhibition of Src Homology 2 Domain-containing Phosphatase 1 (SHP-1) Increases Insulin Sensitivity in High-fat Diet-induced Insulin Resistant C57black6 Mice
Krüger, Janine, Dagnell, Markus, Stawowy, Philipp, Caglayan, Evren, Östman, Arne, Kintscher, Ulrich, Kappert, Kai
Published in Circulation (New York, N.Y.) (25.11.2014)
Published in Circulation (New York, N.Y.) (25.11.2014)
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