Neural Computing in Cancer Drug Development: Predicting Mechanism of Action
Weinstein, John N., Kohn, Kurt W., Grever, Michael R., Viswanadhan, Vellarkad N., Rubinstein, Lawrence V., Monks, Anne P., Scudiero, Dominic A., Welch, Lester, Koutsoukos, Antonis D., Chiausa, August J., Paull, Kenneth D.
Published in Science (American Association for the Advancement of Science) (16.10.1992)
Published in Science (American Association for the Advancement of Science) (16.10.1992)
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Journal Article
Mining and Visualizing Large Anticancer Drug Discovery Databases
Shi, Leming M, Fan, Yi, Lee, Jae K, Waltham, Mark, Andrews, Darren T, Scherf, Uwe, Paull, Kenneth D, Weinstein, John N
Published in Journal of Chemical Information and Computer Sciences (01.03.2000)
Published in Journal of Chemical Information and Computer Sciences (01.03.2000)
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Journal Article
Protein-Linked DNA Strand Breaks Induced by NSC 314622, a Novel Noncamptothecin Topoisomerase I Poison
Kohlhagen, G, Paull, K D, Cushman, M, Nagafuji, P, Pommier, Y
Published in Molecular pharmacology (01.07.1998)
Published in Molecular pharmacology (01.07.1998)
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Journal Article
Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines
SCUDIERO, D. A, SHOEMAKER, R. H, PAULL, K. D, MONKS, A, TIERNEY, S, NOFZIGER, T. H, CURRENS, M. J, SENIFF, D, BOYD, M. R
Published in Cancer research (Chicago, Ill.) (01.09.1988)
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Published in Cancer research (Chicago, Ill.) (01.09.1988)
Journal Article
Identification of Epidermal Growth Factor Receptor and c-erbB2 Pathway Inhibitors by Correlation With Gene Expression Patterns
Wosikowski, Katja, Schuurhuis, Danita, Johnson, Kathryn, Bates, Susan E., Paull, Kenneth D., Myers, Timothy G., Weinstein, John N.
Published in JNCI : Journal of the National Cancer Institute (15.10.1997)
Published in JNCI : Journal of the National Cancer Institute (15.10.1997)
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Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin
Kuo, Sheng Chu, Lee, Hong Zin, Juang, Jung Pin, Lin, Yih Tyng, Wu, Tian Shung, Chang, Jer Jang, Lednicer, Dan, Paull, Kenneth D, Lin, Chii M
Published in Journal of medicinal chemistry (30.04.1993)
Published in Journal of medicinal chemistry (30.04.1993)
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Mining the National Cancer Institute Anticancer Drug Discovery Database: Cluster Analysis of Ellipticine Analogs with p53-Inverse and Central Nervous System-Selective Patterns of Activity
Shi, L M, Myers, T G, Fan, Y, O'Connor, P M, Paull, K D, Friend, S H, Weinstein, J N
Published in Molecular pharmacology (01.02.1998)
Published in Molecular pharmacology (01.02.1998)
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Journal Article
Multidrug-resistant phenotype of disease-oriented panels of human tumor cell lines used for anticancer drug screening
LIN WU, SMYTHE, A. M, SHOEMAKER, R. H, STINSON, S. F, MULLENDORE, L. A, MONKS, A, SCUDIERO, D. A, PAULL, K. D, KOUTSOUKOS, A. D, RUBINSTEIN, L. V, BOYD, M. R
Published in Cancer research (Chicago, Ill.) (01.06.1992)
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Published in Cancer research (Chicago, Ill.) (01.06.1992)
Journal Article
Mining the NCI Anticancer Drug Discovery Databases: Genetic Function Approximation for the QSAR Study of Anticancer Ellipticine Analogues
Shi, Leming M, Fan, Yi, Myers, Timothy G, O'Connor, Patrick M, Paull, Kenneth D, Friend, Stephen H, Weinstein, John N
Published in Journal of Chemical Information and Computer Sciences (01.03.1998)
Published in Journal of Chemical Information and Computer Sciences (01.03.1998)
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Journal Article
Cytotoxicity of a new IMP dehydrogenase inhibitor, benzamide riboside, to human myelogenous leukemia K562 cells
Jayaram, Hiremagalur N., Gharehbaghi, Kamran, Jayaram, Nagesh H., Rieser, Jason, Krohn, Karsten, Paull, Kenneth D.
Published in Biochemical and biophysical research communications (14.08.1992)
Published in Biochemical and biophysical research communications (14.08.1992)
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Journal Article
Cytotoxicity and characterization of an active metabolite of benzamide riboside, a novel inhibitor of IMP dehydrogenase
Gharehbaghi, K, Paull, K D, Kelley, J A, Barchi, Jr, J J, Marquez, V E, Cooney, D A, Monks, A, Scudiero, D, Krohn, K, Jayaram, H N
Published in International journal of cancer (15.03.1994)
Published in International journal of cancer (15.03.1994)
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Design and Synthesis of Ellipticinium Salts and 1,2-Dihydroellipticines with High Selectivities against Human CNS Cancers in vitro
Jurayj, Jurjus, Haugwitz, Rudiger D, Varma, Ravi K, Paull, Kenneth D, Barrett, John F, Cushman, Mark
Published in Journal of medicinal chemistry (01.07.1994)
Published in Journal of medicinal chemistry (01.07.1994)
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Journal Article
Synthesis of the 6- and 7-hydroxy-5,8-dioxocarbostyrils
Pettit, George R, Fleming, Wayne C, Paull, Kenneth D
Published in Journal of organic chemistry (01.03.1968)
Published in Journal of organic chemistry (01.03.1968)
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Journal Article
An Information-Intensive Approach to the Molecular Pharmacology of Cancer
Weinstein, John N., Myers, Timothy G., O'Connor, Patrick M., Friend, Stephen H., Fornace, Albert J., Kohn, Kurt W., Fojo, Tito, Bates, Susan E., Rubinstein, Lawrence V., Anderson, N. Leigh, Buolamwini, John K., van Osdol, William W., Monks, Anne P., Scudiero, Dominic A., Sausville, Edward A., Zaharevitz, Daniel W., Bunow, Barry, Viswanadhan, Vellarkad N., Johnson, George S., Wittes, Robert E., Paull, Kenneth D.
Published in Science (American Association for the Advancement of Science) (17.01.1997)
Published in Science (American Association for the Advancement of Science) (17.01.1997)
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Experimental antileukemic agents. Coralyne, analogs, and related compounds
Zee-Cheng, Kwang-Yuen, Paull, Kenneth D, Cheng, C. C
Published in Journal of medicinal chemistry (01.03.1974)
Published in Journal of medicinal chemistry (01.03.1974)
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Journal Article
Preclinical antitumor activity of batracylin (NSC 320846)
Plowman, J, Paull, K D, Atassi, G, Harrison, Jr, S D, Dykes, D J, Kabbe, H J, Narayanan, V L, Yoder, O C
Published in Investigational new drugs (01.09.1988)
Published in Investigational new drugs (01.09.1988)
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