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Published in Frontiers in pharmacology (16.01.2023)
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Comparative pharmacokinetics and tissue distribution of primaquine enantiomers in mice
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Formation primaquine-5,6-orthoquinone, the putative active and toxic metabolite of primaquine via direct oxidation in human erythrocytes
Fasinu, Pius S, Nanayakkara, N P Dhammika, Wang, Yan-Hong, Chaurasiya, Narayan D, Herath, H M Bandara, McChesney, James D, Avula, Bharathi, Khan, Ikhlas, Tekwani, Babu L, Walker, Larry A
Published in Malaria journal (30.01.2019)
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Metabolism of primaquine in normal human volunteers: investigation of phase I and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry
Avula, Bharathi, Tekwani, Babu L, Chaurasiya, Narayan D, Fasinu, Pius, Dhammika Nanayakkara, N P, Bhandara Herath, H M T, Wang, Yan-Hong, Bae, Ji-Yeong, Khan, Shabana I, Elsohly, Mahmoud A, McChesney, James D, Zimmerman, Peter A, Khan, Ikhlas A, Walker, Larry A
Published in Malaria journal (13.08.2018)
Published in Malaria journal (13.08.2018)
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Comparative single dose pharmacokinetics and metabolism of racemic primaquine and its enantiomers in human volunteers
Khan, Washim, Wang, Yan-Hong, Chaurasiya, Narayan D., Nanayakkara, NP Dhammika, Herath, HM Bandara, Harrison, Kerri A., Dale, Gray, Stanford, Donald A., Dahl, Eric P., McChesney, James D., Gul, Waseem, ElSohly, Mahmoud A., Khan, Shabana I., Fasinu, Pius S., Khan, Ikhlas A., Tekwani, Babu L., Walker, Larry A.
Published in Drug metabolism and pharmacokinetics (01.08.2022)
Published in Drug metabolism and pharmacokinetics (01.08.2022)
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Published in Molecules (Basel, Switzerland) (15.12.2018)
Published in Molecules (Basel, Switzerland) (15.12.2018)
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Enantioselective pharmacokinetics of primaquine in healthy human volunteers
Tekwani, Babu L, Avula, Bharathi, Sahu, Rajnish, Chaurasiya, Narayan D, Khan, Shabana I, Jain, Surendra, Fasinu, Pius S, Herath, H M T Bandara, Stanford, Donald, Nanayakkara, N P Dhammika, McChesney, James D, Yates, Travis W, ElSohly, Mahmoud A, Khan, Ikhlas A, Walker, Larry A
Published in Drug metabolism and disposition (01.04.2015)
Published in Drug metabolism and disposition (01.04.2015)
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Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes
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Published in Malaria journal (19.04.2016)
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Scalable Preparation and Differential Pharmacologic and Toxicologic Profiles of Primaquine Enantiomers
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Published in Antimicrobial agents and chemotherapy (01.08.2014)
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Antiparasitic Activities and Toxicities of Individual Enantiomers of the 8-Aminoquinoline 8-[(4-Amino-1-Methylbutyl)Amino]-6-Methoxy-4-Methyl-5-[3,4-Dichlorophenoxy]Quinoline Succinate
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Published in Antimicrobial Agents and Chemotherapy (01.06.2008)
Published in Antimicrobial Agents and Chemotherapy (01.06.2008)
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Enantioselective metabolism of primaquine by human CYP2D6
Fasinu, Pius S, Tekwani, Babu L, Nanayakkara, N P Dhammika, Avula, Bharathi, Herath, H M T Bandara, Wang, Yan-Hong, Adelli, Vijender R, Elsohly, Mahmoud A, Khan, Shabana I, Khan, Ikhlas A, Pybus, Brandon S, Marcsisin, Sean R, Reichard, Gregory A, McChesney, James D, Walker, Larry A
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Published in Malaria journal (17.12.2014)
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Balancing the efficacy vs. the toxicity of promiscuous natural products: Paclitaxel-based acid-labile lipophilic prodrugs as promising chemotherapeutics
Haider, Saqlain, Penfornis, Patrice, Claudio, Pier Paolo, McChesney, James D., Chittiboyina, Amar G.
Published in European journal of medicinal chemistry (05.01.2022)
Published in European journal of medicinal chemistry (05.01.2022)
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Plant natural products: Back to the future or into extinction?
McChesney, James D., Venkataraman, Sylesh K., Henri, John T.
Published in Phytochemistry (01.07.2007)
Published in Phytochemistry (01.07.2007)
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CUENDET, Muriel, CHRISTOV, Konstantin, LANTVIT, Daniel D, YUNFAN DENG, HEDAYAT, Samad, HELSON, Lawrence, MCCHESNEY, James D, PEZZUTO, John M
Published in Clinical cancer research (01.02.2004)
Published in Clinical cancer research (01.02.2004)
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Assignment of sugar arrangement in branched steviol glycosides using electrospray ionization quadrupole time‐of‐flight tandem mass spectrometry
Perera, Wilmer H., Avula, Bharathi, Khan, Ikhlas A., McChesney, James D.
Published in Rapid communications in mass spectrometry (15.02.2017)
Published in Rapid communications in mass spectrometry (15.02.2017)
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Measurement of paclitaxel in biological matrices: high-throughput liquid chromatographic–tandem mass spectrometric quantification of paclitaxel and metabolites in human and dog plasma
Alexander, Michael S, Kiser, Melissa M, Culley, Travis, Kern, John R, Dolan, John W, McChesney, James D, Zygmunt, Jan, Bannister, Steve J
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.03.2003)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.03.2003)
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Rebaudiosides T and U, minor C-19 xylopyranosyl and arabinopyranosyl steviol glycoside derivatives from Stevia rebaudiana (Bertoni) Bertoni
Perera, Wilmer H., Ghiviriga, Ion, Rodenburg, Douglas L., Alves, Kamilla, Bowling, John J., Avula, Bharathi, Khan, Ikhlas A., McChesney, James D.
Published in Phytochemistry (Oxford) (01.03.2017)
Published in Phytochemistry (Oxford) (01.03.2017)
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