Spontaneous Diabetes Mellitus in Transgenic Mice Expressing Human Islet Amyloid Polypeptide
Janson, Juliette, Soeller, Walter C., Roche, Patrick C., Nelson, Robin T., Torchia, Anthony J., Kreutter, David K., Butler, Peter C.
Published in Proceedings of the National Academy of Sciences - PNAS (09.07.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (09.07.1996)
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Journal Article
Structural basis for isoform-specific inhibition of human CTPS1
Lynch, Eric M., DiMattia, Michael A., Albanese, Steven, van Zundert, Gydo C. P., Hansen, Jesse M., Quispe, Joel D., Kennedy, Madison A., Verras, Andreas, Borrelli, Kenneth, Toms, Angela V., Kaila, Neelu, Kreutter, Kevin D., McElwee, Joshua J., Kollman, Justin M.
Published in Proceedings of the National Academy of Sciences - PNAS (05.10.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (05.10.2021)
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Journal Article
Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide
Soeller, W C, Janson, J, Hart, S E, Parker, J C, Carty, M D, Stevenson, R W, Kreutter, D K, Butler, P C
Published in Diabetes (New York, N.Y.) (01.05.1998)
Published in Diabetes (New York, N.Y.) (01.05.1998)
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Journal Article
Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease
Leonard, Kristi A, Madge, Lisa A, Krawczuk, Paul J, Wang, Aihua, Kreutter, Kevin D, Bacani, Genesis M, Chai, Wenying, Smith, Russell C, Tichenor, Mark S, Harris, Michael C, Malaviya, Ravi, Seierstad, Mark, Johnson, Marguerite E, Venable, Jennifer D, Kim, Suzie, Hirst, Gavin C, Mathur, Ashok S, Rao, Tadimeti S, Edwards, James P, Rizzolio, Michele C, Koudriakova, Tatiana
Published in Journal of medicinal chemistry (26.03.2020)
Published in Journal of medicinal chemistry (26.03.2020)
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Journal Article
Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase
Tichenor, Mark S., Wiener, John J. M., Rao, Navin L., Bacani, Genesis M., Wei, Jianmei, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D., Chang, Leon, Clancy, Kathleen W., Murrey, Heather E., Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J., Wu, Jiejun, Rui, Haopeng, Sepassi, Kia, Gaudiano, Marcello, Bekkers, Mariette, Cornelissen, Ivo, Packman, Kathryn, Seierstad, Mark, Xiouras, Christos, Bembenek, Scott D., Alexander, Richard, Milligan, Cynthia, Balasubramanian, Sriram, Lebsack, Alec D., Venable, Jennifer D., Philippar, Ulrike, Edwards, James P., Hirst, Gavin
Published in Journal of medicinal chemistry (10.11.2022)
Published in Journal of medicinal chemistry (10.11.2022)
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Journal Article
Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt
Kummer, David A., Cummings, Maxwell D., Abad, Marta, Barbay, Joseph, Castro, Glenda, Wolin, Ronald, Kreutter, Kevin D., Maharoof, Umar, Milligan, Cynthia, Nishimura, Rachel, Pierce, Joan, Schalk-Hihi, Celine, Spurlino, John, Urbanski, Maud, Venkatesan, Hariharan, Wang, Aihua, Woods, Craig, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi
Published in Bioorganic & medicinal chemistry letters (01.05.2017)
Published in Bioorganic & medicinal chemistry letters (01.05.2017)
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Journal Article
6-Substituted quinolines as RORγt inverse agonists
Barbay, J. Kent, Cummings, Maxwell D., Abad, Marta, Castro, Glenda, Kreutter, Kevin D., Kummer, David A., Maharoof, Umar, Milligan, Cynthia, Nishimura, Rachel, Pierce, Joan, Schalk-Hihi, Celine, Spurlino, John, Tanis, Virginia M., Urbanski, Maud, Venkatesan, Hariharan, Wang, Aihua, Woods, Craig, Wolin, Ronald, Xue, Xiaohua, Edwards, James P., Fourie, Anne M., Leonard, Kristi
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
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Journal Article
Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction
M Couce, L A Kane, T D O'Brien, J Charlesworth, W Soeller, J McNeish, D Kreutter, P Roche, P C Butler
Published in Diabetes (New York, N.Y.) (01.08.1996)
Published in Diabetes (New York, N.Y.) (01.08.1996)
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Journal Article
Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity
Tichenor, Mark S, Wiener, John J. M, Rao, Navin L, Pooley Deckhut, Charlotte, Barbay, J. Kent, Kreutter, Kevin D, Bacani, Genesis M, Wei, Jianmei, Chang, Leon, Murrey, Heather E, Wang, Weixue, Ahn, Kay, Huber, Michael, Rex, Elizabeth, Coe, Kevin J, Wu, JieJun, Seierstad, Mark, Bembenek, Scott D, Leonard, Kristi A, Lebsack, Alec D, Venable, Jennifer D, Edwards, James P
Published in ACS medicinal chemistry letters (13.05.2021)
Published in ACS medicinal chemistry letters (13.05.2021)
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Journal Article
Human islet amyloid polypeptide expression in COS-1 cells. A model of intracellular amyloidogenesis
O'Brien, TD, Butler, PC, Kreutter, DK, Kane, LA, Eberhardt, NL
Published in The American journal of pathology (01.09.1995)
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Published in The American journal of pathology (01.09.1995)
Journal Article
Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells
Kreutter, D, Caldwell, A B, Morin, M J
Published in The Journal of biological chemistry (25.05.1985)
Published in The Journal of biological chemistry (25.05.1985)
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Journal Article
Regulation of protein kinase C activity by gangliosides
Kreutter, D, Kim, J Y, Goldenring, J R, Rasmussen, H, Ukomadu, C, DeLorenzo, R J, Yu, R K
Published in The Journal of biological chemistry (05.02.1987)
Published in The Journal of biological chemistry (05.02.1987)
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Journal Article
2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors
Lee, Lily, Kreutter, Kevin D., Pan, Wenxi, Crysler, Carl, Spurlino, John, Player, Mark R., Tomczuk, Bruce, Lu, Tianbao
Published in Bioorganic & medicinal chemistry (15.11.2007)
Published in Bioorganic & medicinal chemistry (15.11.2007)
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Journal Article
Amylin-induced in vivo insulin resistance in conscious rats: the liver is more sensitive to amylin than peripheral tissues
Koopmans, S J, van Mansfeld, A D, Jansz, H S, Krans, H M, Radder, J K, Frölich, M, de Boer, S F, Kreutter, D K, Andrews, G C, Maassen, J A
Published in Diabetologia (01.04.1991)
Published in Diabetologia (01.04.1991)
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Journal Article
Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif
Kreutter, Kevin D., Lu, Tianbao, Lee, Lily, Giardino, Edward C., Patel, Sharmila, Huang, Hui, Xu, Guozhang, Fitzgerald, Mark, Haertlein, Barbara J., Mohan, Venkatraman, Crysler, Carl, Eisennagel, Stephen, Dasgupta, Malini, McMillan, Martin, Spurlino, John C., Huebert, Norman D., Maryanoff, Bruce E., Tomczuk, Bruce E., Damiano, Bruce P., Player, Mark R.
Published in Bioorganic & medicinal chemistry (01.05.2008)
Published in Bioorganic & medicinal chemistry (01.05.2008)
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Journal Article
Relationship of age and calcitonin gene-related peptide to postprandial hypotension
Edwards, B.J., Perry, H.M., Kaiser, F.E., Morley, J.E., Kraenzle, D., Stevenson, R., Kreutter, D.
Published in Mechanisms of ageing and development (07.06.1996)
Published in Mechanisms of ageing and development (07.06.1996)
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