HDAC6 is a target for protection and regeneration following injury in the nervous system
Rivieccio, Mark A, Brochier, Camille, Willis, Dianna E, Walker, Breset A, D'Annibale, Melissa A, McLaughlin, Kathryn, Siddiq, Ambreena, Kozikowski, Alan P, Jaffrey, Samie R, Twiss, Jeffery L, Ratan, Rajiv R, Langley, Brett
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.11.2009)
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Journal Article
Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/cip1) in cell cycle-independent neuroprotection
Langley, Brett, D'Annibale, Melissa A, Suh, Kyungsun, Ayoub, Issam, Tolhurst, Aaron, Bastan, Birgül, Yang, Lichuan, Ko, Brian, Fisher, Marc, Cho, Sunghee, Beal, M Flint, Ratan, Rajiv R
Published in The Journal of neuroscience (02.01.2008)
Published in The Journal of neuroscience (02.01.2008)
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Journal Article
Functional Differences in Epigenetic ModulatorsSuperiority of Mercaptoacetamide-Based Histone Deacetylase Inhibitors Relative to Hydroxamates in Cortical Neuron Neuroprotection Studies
Kozikowski, Alan P, Chen, Yufeng, Gaysin, Arsen, Chen, Bin, D'Annibale, Melissa A, Suto, Carla M, Langley, Brett C
Published in Journal of medicinal chemistry (28.06.2007)
Published in Journal of medicinal chemistry (28.06.2007)
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Journal Article
Studies of Benzamide- and Thiol-Based Histone Deacetylase Inhibitors in Models of Oxidative-Stress-Induced Neuronal Death: Identification of Some HDAC3-Selective Inhibitors
Chen, Yufeng, He, Rong, Chen, Yihua, D'Annibale, Melissa A., Langley, Brett, Kozikowski, Alan P.
Published in ChemMedChem (11.05.2009)
Published in ChemMedChem (11.05.2009)
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Journal Article
A myristoylated alanine-rich C kinase substrate-related peptide suppresses cytokine mRNA and protein expression in LPS-activated canine neutrophils
Li, Jingjing, D'Annibale-Tolhurst, Melissa A, Adler, Kenneth B, Fang, Shijing, Yin, Qui, Birkenheuer, Adam J, Levy, Michael G, Jones, Samuel L, Sung, Eui Jae, Hawkins, Eleanor C, Yoder, Jeffrey A, Nordone, Shila K
Published in American journal of respiratory cell and molecular biology (01.03.2013)
Published in American journal of respiratory cell and molecular biology (01.03.2013)
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Searching for Disease Modifiers—PKC Activation and HDAC Inhibition—A Dual Drug Approach to Alzheimer's Disease that Decreases Aβ Production while Blocking Oxidative Stress
Kozikowski, Alan P., Chen, Yihua, Subhasish, Tapadar, Lewin, Nancy E., Blumberg, Peter M., Zhong, Zhenyu, D'Annibale, Melissa A., Wang, Weng‐Long, Shen, Yong, Langley, Brett
Published in ChemMedChem (06.07.2009)
Published in ChemMedChem (06.07.2009)
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Journal Article
Pulse Inhibition of Histone Deacetylases Induces Complete Resistance to Oxidative Death in Cortical Neurons without Toxicity and Reveals a Role for Cytoplasmic p21waf1/cip1 in Cell Cycle-Independent Neuroprotection
Langley, Brett, D'Annibale, Melissa A, Suh, Kyungsun, Ayoub, Issam, Tolhurst, Aaron, Bastan, Birgul, Yang, Lichuan, Ko, Brian, Fisher, Marc, Cho, Sunghee, Beal, M. Flint, Ratan, Rajiv R
Published in The Journal of neuroscience (02.01.2008)
Published in The Journal of neuroscience (02.01.2008)
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Journal Article
Functional Differences in Epigenetic ModulatorsSuperiority of Mercaptoacetamide-Based Histone Deacetylase Inhibitors Relative to Hydroxamates in Cortical Neuron Neuroprotection Studies
Kozikowski, Alan P., Chen, Yufeng, Gaysin, Arsen, Chen, Bin, D'Annibale, Melissa A., Suto, Carla M., Langley, Brett C.
Published in Journal of medicinal chemistry (01.06.2007)
Published in Journal of medicinal chemistry (01.06.2007)
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Journal Article
Tumor Necrosis Factor (TNF)-Alpha Induces Luteolytic Sensitivity in Porcine Luteal Cells by Activating the Intra-Luteal Prostaglandin (PG) Pathway
Gadsby, John E., D'Annibale, Melissa, Gannon, Morgan, Albers, Lynn, Zorrilla, Leah
Published in Biology of reproduction (01.07.2009)
Published in Biology of reproduction (01.07.2009)
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Journal Article
Pulse Inhibition of Histone Deacetylases Induces Complete Resistance to Oxidative Death in Cortical Neurons without Toxicity and Reveals a Role for Cytoplasmic p21 super(waf1/cip1) in Cell Cycle-Independent Neuroprotection
Langley, Brett, D'Annibale, Melissa A, Suh, Kyungsun, Ayoub, Issam, Tolhurst, Aaron, Bastan, Birguel, Yang, Lichuan, Ko, Brian, Fisher, Marc, Cho, Sunghee, Beal, MFlint, Ratan, Rajiv R
Published in The Journal of neuroscience (02.01.2008)
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Published in The Journal of neuroscience (02.01.2008)
Journal Article
Pulse Inhibition of Histone Deacetylases Induces Complete Resistance to Oxidative Death in Cortical Neurons without Toxicity and Reveals a Role for Cytoplasmic p21 waf1/cip1 in Cell Cycle-Independent Neuroprotection
Langley, Brett, D'Annibale, Melissa A., Suh, Kyungsun, Ayoub, Issam, Tolhurst, Aaron, Bastan, Birgül, Yang, Lichuan, Ko, Brian, Fisher, Marc, Cho, Sunghee, Beal, M. Flint, Ratan, Rajiv R.
Published in The Journal of neuroscience (02.01.2008)
Published in The Journal of neuroscience (02.01.2008)
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Journal Article
Searching for Disease Modifiers - PKC Activation and HDAC Inhibition - A Dual Drug Approach to Alzheimer's Disease that Decreases A Delta b Production while Blocking Oxidative Stress
Kozikowski, Alan P, Chen, Yihua, Subhasish, Tapadar, Lewin, Nancy E, Blumberg, Peter M, Zhong, Zhenyu, D'Annibale, Melissa A, Wang, Weng-Long, Shen, Yong, Langley, Brett
Published in ChemMedChem (06.07.2009)
Published in ChemMedChem (06.07.2009)
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Journal Article
Searching for Disease Modifiers - PKC Activation and HDAC Inhibition - A Dual Drug Approach to Alzheimer's Disease that Reduces Aβ Production while Blocking Oxidative Stress
Kozikowski, Alan P., Chen, Yihua, Subhasish, Tapadar, Lewin, Nancy E., Blumberg, Peter M., Zhong, Zhenyu, D'Annibale, Melissa A., Wang, Weng-Long, Shen, Yong, Langley, Brett C.
Published in ChemMedChem (06.07.2009)
Published in ChemMedChem (06.07.2009)
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Journal Article
Searching for disease modifiers-PKC activation and HDAC inhibition - a dual drug approach to Alzheimer's disease that decreases Abeta production while blocking oxidative stress
Kozikowski, Alan P, Chen, Yihua, Subhasish, Tapadar, Lewin, Nancy E, Blumberg, Peter M, Zhong, Zhenyu, D'Annibale, Melissa A, Wang, Weng-Long, Shen, Yong, Langley, Brett
Published in ChemMedChem (01.07.2009)
Published in ChemMedChem (01.07.2009)
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Journal Article
MARCKS protein plays a critical role in proinflammatory cytokine production (160.7)
Nordone, Shila, Li, Jingjing, D’Annibale, Melissa, Birkenheuer, Adam, Levy, Mike, Yoder, Jeff, Jones, Sam, Adler, Ken
Published in The Journal of immunology (1950) (01.05.2012)
Published in The Journal of immunology (1950) (01.05.2012)
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Journal Article
A Myristoylated Alanine-Rich C Kinase Substrate-Related Peptide Suppresses Cytokine mRNA and Protein Expression in LPS-Activated Canine Neutrophils
Li, Jingjing, D'Annibale-Tolhurst, Melissa A, Adler, Kenneth B, Fang, Shijing, Yin, Qui, Birkenheuer, Adam J, Levy, Michael G, Jones, Samuel L, Sung, Eui Jae, Hawkins, Eleanor C, Yoder, Jeffrey A, Nordone, Shila K
Published in American journal of respiratory cell and molecular biology (01.03.2013)
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Published in American journal of respiratory cell and molecular biology (01.03.2013)
Journal Article