Zebrafish: Speeding Up the Cancer Drug Discovery Process
Letrado, Patricia, de Miguel, Irene, Lamberto, Iranzu, Díez-Martínez, Roberto, Oyarzabal, Julen
Published in Cancer research (Chicago, Ill.) (01.11.2018)
Published in Cancer research (Chicago, Ill.) (01.11.2018)
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Journal Article
Improving the Lethal Effect of Cpl-7, a Pneumococcal Phage Lysozyme with Broad Bactericidal Activity, by Inverting the Net Charge of Its Cell Wall-Binding Module
DIEZ-MARTINEZ, Roberto, DE PAZ, Héctor, BUSTAMANTE, Noemí, GARCIA, Ernesto, MENENDEZ, Margarita, GARCIA, Pedro
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
Published in Antimicrobial Agents and Chemotherapy (01.11.2013)
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Journal Article
Learning from –omics strategies applied to uncover Haemophilus influenzae host-pathogen interactions: Current status and perspectives
López-López, Nahikari, Gil-Campillo, Celia, Díez-Martínez, Roberto, Garmendia, Junkal
Published in Computational and structural biotechnology journal (01.01.2021)
Published in Computational and structural biotechnology journal (01.01.2021)
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Journal Article
In Vivo Genome-Wide Gene Expression Profiling Reveals That Haemophilus influenzae Purine Synthesis Pathway Benefits Its Infectivity within the Airways
Euba, Begoña, Gil-Campillo, Celia, Asensio-López, Javier, López-López, Nahikari, Sen-Kilic, Emel, Díez-Martínez, Roberto, Burgui, Saioa, Barbier, Mariette, Garmendia, Junkal
Published in Microbiology spectrum (15.06.2023)
Published in Microbiology spectrum (15.06.2023)
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Journal Article
Essential Topics for the Regulatory Consideration of Phages as Clinically Valuable Therapeutic Agents: A Perspective from Spain
Vázquez, Roberto, Díez-Martínez, Roberto, Domingo-Calap, Pilar, García, Pedro, Gutiérrez, Diana, Muniesa, Maite, Ruiz-Ruigómez, María, Sanjuán, Rafael, Tomás, María, Tormo-Mas, María Ángeles, García, Pilar
Published in Microorganisms (Basel) (26.03.2022)
Published in Microorganisms (Basel) (26.03.2022)
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Interrogation of Essentiality in the Reconstructed Haemophilus influenzae Metabolic Network Identifies Lipid Metabolism Antimicrobial Targets: Preclinical Evaluation of a FabH β-Ketoacyl-ACP Synthase Inhibitor
López-López, Nahikari, León, David San, de Castro, Sonia, Díez-Martínez, Roberto, Iglesias-Bexiga, Manuel, Camarasa, María José, Menéndez, Margarita, Nogales, Juan, Garmendia, Junkal
Published in mSystems (26.04.2022)
Published in mSystems (26.04.2022)
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Journal Article
Haemophilus influenzae Glucose Catabolism Leading to Production of the Immunometabolite Acetate Has a Key Contribution to the Host Airway–Pathogen Interplay
López-López, Nahikari, Euba, Begoña, Hill, Julian, Dhouib, Rabeb, Caballero, Lucı́a, Leiva, José, Hosmer, Jennifer, Cuesta, Sergio, Ramos-Vivas, José, Díez-Martínez, Roberto, Schirra, Horst Joachim, Blank, Lars M, Kappler, Ulrike, Garmendia, Junkal
Published in ACS infectious diseases (13.03.2020)
Published in ACS infectious diseases (13.03.2020)
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Journal Article
Macrolides and β-Lactam Antibiotics Enhance C3b Deposition on the Surface of Multidrug-Resistant Streptococcus pneumoniae Strains by a LytA Autolysin-Dependent Mechanism
RAMOS-SEVILLANO, Elisa, RODRIGUEZ-SOSA, Cinthya, DIEZ-MARTINEZ, Roberto, GIMENEZ, María-José, OLMEDILLAS, Eduardo, GARCIA, Pedro, GARCIA, Ernesto, AGUILAR, Lorenzo, YUSTE, Jose
Published in Antimicrobial Agents and Chemotherapy (01.11.2012)
Published in Antimicrobial Agents and Chemotherapy (01.11.2012)
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Journal Article
Auranofin-loaded nanoparticles as a new therapeutic tool to fight streptococcal infections
Díez-Martínez, Roberto, García-Fernández, Esther, Manzano, Miguel, Martínez, Ángel, Domenech, Mirian, Vallet-Regí, María, García, Pedro
Published in Scientific reports (18.01.2016)
Published in Scientific reports (18.01.2016)
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Journal Article
Systematic Roadmap for Cancer Drug Screening Using Zebrafish Embryo Xenograft Cancer Models: Melanoma Cell Line as a Case Study
Letrado, Patricia, Mole, Holly, Montoya, María, Palacios, Irene, Barriuso, Jorge, Hurlstone, Adam, Díez-Martínez, Roberto, Oyarzabal, Julen
Published in Cancers (23.07.2021)
Published in Cancers (23.07.2021)
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Journal Article
Aromatic Esters of Bicyclic Amines as Antimicrobials against Streptococcus pneumoniae
de Gracia Retamosa, María, Díez-Martínez, Roberto, Maestro, Beatriz, García-Fernández, Esther, de Waal, Bas, Meijer, E. W., García, Pedro, Sanz, Jesús M.
Published in Angewandte Chemie International Edition (09.11.2015)
Published in Angewandte Chemie International Edition (09.11.2015)
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Journal Article
Novel phage lysin capable of killing the multidrug-resistant gram-negative bacterium Acinetobacter baumannii in a mouse bacteremia model
Lood, Rolf, Winer, Benjamin Y, Pelzek, Adam J, Diez-Martinez, Roberto, Thandar, Mya, Euler, Chad W, Schuch, Raymond, Fischetti, Vincent A
Published in Antimicrobial agents and chemotherapy (01.04.2015)
Published in Antimicrobial agents and chemotherapy (01.04.2015)
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Journal Article
A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae
Díez-Martínez, Roberto, De Paz, Héctor D, García-Fernández, Esther, Bustamante, Noemí, Euler, Chad W, Fischetti, Vincent A, Menendez, Margarita, García, Pedro
Published in Journal of antimicrobial chemotherapy (01.06.2015)
Published in Journal of antimicrobial chemotherapy (01.06.2015)
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Journal Article
Chemotherapy with Phage Lysins Reduces Pneumococcal Colonization of the Respiratory Tract
Corsini, Bruno, Díez-Martínez, Roberto, Aguinagalde, Leire, González-Camacho, Fernando, García-Fernández, Esther, Letrado, Patricia, García, Pedro, Yuste, Jose
Published in Antimicrobial agents and chemotherapy (01.06.2018)
Published in Antimicrobial agents and chemotherapy (01.06.2018)
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Journal Article
Resveratrol therapeutics combines both antimicrobial and immunomodulatory properties against respiratory infection by nontypeable Haemophilus influenzae
Euba, Begoña, López-López, Nahikari, Rodríguez-Arce, Irene, Fernández-Calvet, Ariadna, Barberán, Montserrat, Caturla, Nuria, Martí, Sara, Díez-Martínez, Roberto, Garmendia, Junkal
Published in Scientific reports (16.10.2017)
Published in Scientific reports (16.10.2017)
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Journal Article
Auranofin efficacy against MDR Streptococcus pneumoniae and Staphylococcus aureus infections
Aguinagalde, Leire, Díez-Martínez, Roberto, Yuste, Jose, Royo, Inmaculada, Gil, Carmen, Lasa, Íñigo, Martín-Fontecha, Mar, Marín-Ramos, Nagore Isabel, Ardanuy, Carmen, Liñares, Josefina, García, Pedro, García, Ernesto, Sánchez-Puelles, José M
Published in Journal of antimicrobial chemotherapy (01.09.2015)
Published in Journal of antimicrobial chemotherapy (01.09.2015)
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Journal Article
Aromatic Esters of Bicyclic Amines as Antimicrobials against Streptococcus pneumoniae
de Gracia Retamosa, María, Díez-Martínez, Roberto, Maestro, Beatriz, García-Fernández, Esther, de Waal, Bas, Meijer, E. W., García, Pedro, Sanz, Jesús M.
Published in Angewandte Chemie (09.11.2015)
Published in Angewandte Chemie (09.11.2015)
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Journal Article
Substrate recognition and catalysis by LytB, a pneumococcal peptidoglycan hydrolase involved in virulence
Rico-Lastres, Palma, Díez-Martínez, Roberto, Iglesias-Bexiga, Manuel, Bustamante, Noemí, Aldridge, Christine, Hesek, Dusan, Lee, Mijoon, Mobashery, Shahriar, Gray, Joe, Vollmer, Waldemar, García, Pedro, Menéndez, Margarita
Published in Scientific reports (05.11.2015)
Published in Scientific reports (05.11.2015)
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