A Protein Misfolding Shaking Amplification-based method for the spontaneous generation of hundreds of bona fide prions
Eraña, Hasier, Sampedro-Torres-Quevedo, Cristina, Charco, Jorge M., Díaz-Domínguez, Carlos M., Peccati, Francesca, San-Juan-Ansoleaga, Maitena, Vidal, Enric, Gonçalves-Anjo, Nuno, Pérez-Castro, Miguel A., González-Miranda, Ezequiel, Piñeiro, Patricia, Fernández-Veiga, Leire, Galarza-Ahumada, Josu, Fernández-Muñoz, Eva, Perez de Nanclares, Guiomar, Telling, Glenn, Geijo, Mariví, Jiménez-Osés, Gonzalo, Castilla, Joaquín
Published in Nature communications (08.03.2024)
Published in Nature communications (08.03.2024)
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Journal Article
Glycans are not necessary to maintain the pathobiological features of bovine spongiform encephalopathy
Otero, Alicia, Barrio, Tomás, Eraña, Hasier, Charco, Jorge M, Betancor, Marina, Díaz-Domínguez, Carlos M, Marín, Belén, Andréoletti, Olivier, Torres, Juan M, Kong, Qingzhong, Badiola, Juan J, Bolea, Rosa, Castilla, Joaquín
Published in PLoS pathogens (07.10.2022)
Published in PLoS pathogens (07.10.2022)
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Journal Article
Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies
Eraña, Hasier, Charco, Jorge M, Di Bari, Michele A, Díaz-Domínguez, Carlos M, López-Moreno, Rafael, Vidal, Enric, González-Miranda, Ezequiel, Pérez-Castro, Miguel A, García-Martínez, Sandra, Bravo, Susana, Fernández-Borges, Natalia, Geijo, Mariví, D'Agostino, Claudia, Garrido, Joseba, Bian, Jifeng, König, Anna, Uluca-Yazgi, Boran, Sabate, Raimon, Khaychuk, Vadim, Vanni, Ilaria, Telling, Glenn C, Heise, Henrike, Nonno, Romolo, Requena, Jesús R, Castilla, Joaquín
Published in PLoS pathogens (23.10.2019)
Published in PLoS pathogens (23.10.2019)
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Journal Article
Understanding the key features of the spontaneous formation of bona fide prions through a novel methodology that enables their swift and consistent generation
Eraéa, Hasier, Díaz-Domínguez, Carlos M, Charco, Jorge M, Vidal, Enric, González-Miranda, Ezequiel, Pérez-Castro, Miguel A, Piéeiro, Patricia, López-Moreno, Rafael, Sampedro-Torres-Quevedo, Cristina, Fernández-Veiga, Leire, Tasis-Galarza, Juan, Lorenzo, Nuria L, Santini-Santiago, Aileen, Lázaro, Melisa, García-Martínez, Sandra, Gonçalves-Anjo, Nuno, San-Juan-Ansoleaga, Maitena, Galarza-Ahumada, Josu, Fernández-Muéoz, Eva, Giler, Samanta, Valle, Mikel, Telling, Glenn C, Geijó, Mariví, Requena, Jesús R, Castilla, Joaquín
Published in Acta neuropathologica communications (07.09.2023)
Published in Acta neuropathologica communications (07.09.2023)
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Journal Article
Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model
Vidal, Enric, Sánchez-Martín, Manuel A, Eraña, Hasier, Lázaro, Sonia Pérez, Pérez-Castro, Miguel A, Otero, Alicia, Charco, Jorge M, Marín, Belén, López-Moreno, Rafael, Díaz-Domínguez, Carlos M, Geijo, Mariví, Ordóñez, Montserrat, Cantero, Guillermo, di Bari, Michele, Lorenzo, Nuria L, Pirisinu, Laura, d'Agostino, Claudia, Torres, Juan María, Béringue, Vincent, Telling, Glenn, Badiola, Juan J, Pumarola, Martí, Bolea, Rosa, Nonno, Romolo, Requena, Jesús R, Castilla, Joaquín
Published in Acta neuropathologica communications (13.12.2022)
Published in Acta neuropathologica communications (13.12.2022)
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Journal Article
Detection of Pathognomonic Biomarker PrPSc and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases
Eraña, Hasier, Charco, Jorge M., González-Miranda, Ezequiel, García-Martínez, Sandra, López-Moreno, Rafael, Pérez-Castro, Miguel A., Díaz-Domínguez, Carlos M., García-Salvador, Adrián, Castilla, Joaquín
Published in Biomolecules (Basel, Switzerland) (19.03.2020)
Published in Biomolecules (Basel, Switzerland) (19.03.2020)
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Journal Article
Description of the first Spanish case of Gerstmann–Sträussler–Scheinker disease with A117V variant: clinical, histopathological and biochemical characterization
Eraña, Hasier, San Millán, Beatriz, Díaz-Domínguez, Carlos M., Charco, Jorge M., Rodríguez, Rosa, Viéitez, Irene, Pereda, Arrate, Yañez, Rosa, Geijo, Mariví, Navarro, Carmen, Perez de Nanclares, Guiomar, Teijeira, Susana, Castilla, Joaquín
Published in Journal of neurology (01.08.2022)
Published in Journal of neurology (01.08.2022)
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Journal Article
A Novel, Reliable and Highly Versatile Method to Evaluate Different Prion Decontamination Procedures
Eraña, Hasier, Pérez-Castro, Miguel Ángel, García-Martínez, Sandra, Charco, Jorge M., López-Moreno, Rafael, Díaz-Dominguez, Carlos M., Barrio, Tomás, González-Miranda, Ezequiel, Castilla, Joaquín
Published in Frontiers in bioengineering and biotechnology (29.10.2020)
Published in Frontiers in bioengineering and biotechnology (29.10.2020)
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Journal Article
Development of a New largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies
Eraña, Hasier, Charco, Jorge M, Di Bari, Michele A, Díaz Domínguez, Carlos M, López Moreno, Rafael, Vidal, Enric, González Miranda, Ezequiel, Pérez Castro, Miguel A, García Martínez, Sandra, Bravo, Susana, Fernández Borges, Natalia, Geijo, Mariví, Agostino, Claudia D, Garrido, Joseba, Bian, Jifeng, König, Anna, Uluca Yazgi, Boran, Sabate Lagunas, Raimon, Khaychuk, Vadim, Vanni, Ilaria, Telling, Glenn C, Heise, Henrike, Nonno, Romolo, Requena, Jesús R, Castilla, Joaquín
Published in PLoS pathogens (23.10.2019)
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Published in PLoS pathogens (23.10.2019)
Journal Article
Detection of Pathognomonic Biomarker PrP Sc and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases
Eraña, Hasier, Charco, Jorge M, González-Miranda, Ezequiel, García-Martínez, Sandra, López-Moreno, Rafael, Pérez-Castro, Miguel A, Díaz-Domínguez, Carlos M, García-Salvador, Adrián, Castilla, Joaquín
Published in Biomolecules (Basel, Switzerland) (19.03.2020)
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Published in Biomolecules (Basel, Switzerland) (19.03.2020)
Journal Article
Detection of Pathognomonic Biomarker [PrP.sup.Sc] and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases
Erana, Hasier, Charco, Jorge M, Gonzalez-Miranda, Ezequiel, Garcia-Martinez, Sandra, Lopez-Moreno, Rafael, Perez-Castro, Miguel A, Diaz-Dominguez, Carlos M, Garcia-Salvador, Adrian, Castilla, Joaquin
Published in Biomolecules (Basel, Switzerland) (01.03.2020)
Published in Biomolecules (Basel, Switzerland) (01.03.2020)
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Journal Article