AAV5-miHTT gene therapy demonstrates suppression of mutant huntingtin aggregation and neuronal dysfunction in a rat model of Huntington's disease
Miniarikova, J, Zimmer, V, Martier, R, Brouwers, C C, Pythoud, C, Richetin, K, Rey, M, Lubelski, J, Evers, M M, van Deventer, S J, Petry, H, Déglon, N, Konstantinova, P
Published in Gene therapy (01.10.2017)
Published in Gene therapy (01.10.2017)
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BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities
Quesseveur, G, David, D J, Gaillard, M C, Pla, P, Wu, M V, Nguyen, H T, Nicolas, V, Auregan, G, David, I, Dranovsky, A, Hantraye, P, Hen, R, Gardier, A M, Déglon, N, Guiard, B P
Published in Translational psychiatry (30.04.2013)
Published in Translational psychiatry (30.04.2013)
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Gene transfer engineering for astrocyte-specific silencing in the CNS
Merienne, N, Delzor, A, Viret, A, Dufour, N, Rey, M, Hantraye, P, Déglon, N
Published in Gene therapy (01.10.2015)
Published in Gene therapy (01.10.2015)
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Implication of the JNK pathway in a rat model of Huntington's disease
Perrin, V., Dufour, N., Raoul, C., Hassig, R., Brouillet, E., Aebischer, P., Luthi-Carter, R., Déglon, N.
Published in Experimental neurology (2009)
Published in Experimental neurology (2009)
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Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study
Bloch, J, Bachoud-Lévi, A C, Déglon, N, Lefaucheur, J P, Winkel, L, Palfi, S, Nguyen, J P, Bourdet, C, Gaura, V, Remy, P, Brugières, P, Boisse, M-F, Baudic, S, Cesaro, P, Hantraye, P, Aebischer, P, Peschanski, M
Published in Human gene therapy (01.10.2004)
Published in Human gene therapy (01.10.2004)
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Lentiviral nigral delivery of GDNF does not prevent neurodegeneration in a genetic rat model of Parkinson's disease
Lo Bianco, C., Déglon, N., Pralong, W., Aebischer, P.
Published in Neurobiology of disease (01.11.2004)
Published in Neurobiology of disease (01.11.2004)
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Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease
Régulier, E, Pereira de Almeida, L, Sommer, B, Aebischer, P, Déglon, N
Published in Human gene therapy (01.11.2002)
Published in Human gene therapy (01.11.2002)
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Complete and Long-Term Rescue of Lesioned Adult Motoneurons by Lentiviral-Mediated Expression of Glial Cell Line-Derived Neurotrophic Factor in the Facial Nucleus
Hottinger, Andreas F, Azzouz, Mimoun, Deglon, Nicole, Aebischer, Patrick, Zurn, Anne D
Published in The Journal of neuroscience (01.08.2000)
Published in The Journal of neuroscience (01.08.2000)
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Neuroprotective gene therapy for Huntington's disease using a polymer encapsulated BHK cell line engineered to secrete human CNTF
Bachoud-Lévi, A C, Déglon, N, Nguyen, J P, Bloch, J, Bourdet, C, Winkel, L, Rémy, P, Goddard, M, Lefaucheur, J P, Brugières, P, Baudic, S, Cesaro, P, Peschanski, M, Aebischer, P
Published in Human gene therapy (10.08.2000)
Published in Human gene therapy (10.08.2000)
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Isolation of Multipotent Neural Precursors Residing in the Cortex of the Adult Human Brain
Arsenijevic, Yvan, Villemure, Jean-Guy, Brunet, Jean-François, Bloch, Jocelyne J., Déglon, Nicole, Kostic, Corinne, Zurn, Anne, Aebischer, Patrick
Published in Experimental neurology (01.07.2001)
Published in Experimental neurology (01.07.2001)
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Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease
Déglon, N, Tseng, J L, Bensadoun, J C, Zurn, A D, Arsenijevic, Y, Pereira de Almeida, L, Zufferey, R, Trono, D, Aebischer, P
Published in Human gene therapy (01.01.2000)
Published in Human gene therapy (01.01.2000)
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Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients
Aebischer, P, Schluep, M, Déglon, N, Joseph, J M, Hirt, L, Heyd, B, Goddard, M, Hammang, J P, Zurn, A D, Kato, A C, Regli, F, Baetge, E E
Published in Nature medicine (01.06.1996)
Published in Nature medicine (01.06.1996)
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Lentiviral Gene Transfer to the Nonhuman Primate Brain
Kordower, Jeffrey H, Bloch, Jocelyne, Ma, Shuang Y, Chu, Yaping, Palfi, Stéphane, Roitberg, Ben Zion, Emborg, Marina, Hantraye, Philippe, Déglon, Nicole, Aebischer, Patrick
Published in Experimental neurology (01.11.1999)
Published in Experimental neurology (01.11.1999)
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Lentiviral Vectors as a Gene Delivery System in the Mouse Midbrain: Cellular and Behavioral Improvements in a 6-OHDA Model of Parkinson's Disease Using GDNF
Bensadoun, Jean-Charles, Déglon, Nicole, Tseng, Jack L., Ridet, Jean-Luc, Zurn, Anne D., Aebischer, Patrick
Published in Experimental neurology (01.07.2000)
Published in Experimental neurology (01.07.2000)
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Gene Transfer into Neurons from Hippocampal Slices: Comparison of Recombinant Semliki Forest Virus, Adenovirus, Adeno-Associated Virus, Lentivirus, and Measles Virus
Ehrengruber, Markus U., Hennou, Sonia, Büeler, Hansruedi, Naim, Hussein Y., Déglon, Nicole, Lundstrom, Kenneth
Published in Molecular and cellular neuroscience (01.05.2001)
Published in Molecular and cellular neuroscience (01.05.2001)
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