Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors
Van Hout, Anneleen, D'huys, Thomas, Oeyen, Merel, Schols, Dominique, Van Loy, Tom
Published in PloS one (14.04.2017)
Published in PloS one (14.04.2017)
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New AMD3100 derivatives for CXCR4 chemokine receptor targeted molecular imaging studies: synthesis, anti-HIV-1 evaluation and binding affinities
Poty, Sophie, Désogère, Pauline, Goze, Christine, Boschetti, Frédéric, D'huys, Thomas, Schols, Dominique, Cawthorne, Christopher, Archibald, Stephen J, Maëcke, Helmut R, Denat, Franck
Published in Dalton transactions : an international journal of inorganic chemistry (21.03.2015)
Published in Dalton transactions : an international journal of inorganic chemistry (21.03.2015)
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The Low-Cost Compound Lignosulfonic Acid (LA) Exhibits Broad-Spectrum Anti-HIV and Anti-HSV Activity and Has Potential for Microbicidal Applications
Gordts, Stephanie C, Férir, Geoffrey, D'huys, Thomas, Petrova, Mariya I, Lebeer, Sarah, Snoeck, Robert, Andrei, Graciela, Schols, Dominique
Published in PloS one (01.07.2015)
Published in PloS one (01.07.2015)
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Carbohydrate-binding protein from stinging nettle as fusion inhibitor for SARS-CoV-2 variants of concern
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Published in Frontiers in cellular and infection microbiology (30.08.2022)
Published in Frontiers in cellular and infection microbiology (30.08.2022)
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64Cu PET Imaging of the CXCR4 Chemokine Receptor Using a Cross-Bridged Cyclam Bis-Tetraazamacrocyclic Antagonist
Burke, Benjamin P, Miranda, Cecilia S, Lee, Rhiannon E, Renard, Isaline, Nigam, Shubhanchi, Clemente, Gonçalo S, D'Huys, Thomas, Ruest, Torsten, Domarkas, Juozas, Thompson, James A, Hubin, Timothy J, Schols, Dominique, Cawthorne, Christopher J, Archibald, Stephen J
Published in The Journal of nuclear medicine (1978) (01.01.2020)
Published in The Journal of nuclear medicine (1978) (01.01.2020)
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Rigid Macrocycle Metal Complexes as CXCR4 Chemokine Receptor Antagonists: Influence of Ring Size
Renard, Isaline, D’huys, Thomas, Burke, Benjamin P., Ajoleza, Trisha, Cain, Amy N., Funwie, Neil L., Khan, Abid, Maples, Danny L., Maples, Randall D., Matz, Dallas L., McRobbie, Graeme, Ullom, Robert, Prior, Timothy J., Linder, Douglas P., Van Loy, Tom, Hubin, Timothy J., Schols, Dominique, Archibald, Stephen J.
Published in Pharmaceutics (28.07.2024)
Published in Pharmaceutics (28.07.2024)
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64 Cu PET Imaging of the CXCR4 Chemokine Receptor Using a Cross-Bridged Cyclam Bis-Tetraazamacrocyclic Antagonist
Burke, Benjamin P, Miranda, Cecilia S, Lee, Rhiannon E, Renard, Isaline, Nigam, Shubhanchi, Clemente, Gonçalo S, D'Huys, Thomas, Ruest, Torsten, Domarkas, Juozas, Thompson, James A, Hubin, Timothy J, Schols, Dominique, Cawthorne, Christopher J, Archibald, Stephen J
Published in Journal of Nuclear Medicine (01.01.2020)
Published in Journal of Nuclear Medicine (01.01.2020)
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Acetate as a model for aspartate-based CXCR4 chemokine receptor binding of cobalt and nickel complexes of cross-bridged tetraazamacrocycles
Cain, Amy N, Carder Freeman, TaRynn N, Roewe, Kimberly D, Cockriel, David L, Hasley, Travis R, Maples, Randall D, Allbritton, Elisabeth M A, D'Huys, Thomas, van Loy, Tom, Burke, Benjamin P, Prior, Timothy J, Schols, Dominique, Archibald, Stephen J, Hubin, Timothy J
Published in Dalton transactions : an international journal of inorganic chemistry (19.02.2019)
Published in Dalton transactions : an international journal of inorganic chemistry (19.02.2019)
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Biological characterization of ligands targeting the human CC chemokine receptor 8 (CCR8) reveals the biased signaling properties of small molecule agonists
Liu, Libao, Doijen, Jordi, D'huys, Thomas, Verhaegen, Yenthel, Dehaen, Wim, De Jonghe, Steven, Schols, Dominique, Van Loy, Tom
Published in Biochemical pharmacology (01.06.2021)
Published in Biochemical pharmacology (01.06.2021)
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IV restriction: a new configuration for metal bis-cyclam complexes as potent CXCR4 inhibitors
Alzahrani, Seraj O, McRobbie, Graeme, Khan, Abid, D'huys, Thomas, Van Loy, Tom, Walker, Ashlie N, Renard, Isaline, Hubin, Timothy J, Schols, Dominique, Burke, Benjamin P, Archibald, Stephen J
Published in Dalton transactions : an international journal of inorganic chemistry (19.03.2024)
Published in Dalton transactions : an international journal of inorganic chemistry (19.03.2024)
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trans -IV restriction: a new configuration for metal bis-cyclam complexes as potent CXCR4 inhibitors
Alzahrani, Seraj O, McRobbie, Graeme, Khan, Abid, D'huys, Thomas, Van Loy, Tom, Walker, Ashlie N, Renard, Isaline, Hubin, Timothy J, Schols, Dominique, Burke, Benjamin P, Archibald, Stephen J
Published in Dalton transactions : an international journal of inorganic chemistry (19.03.2024)
Published in Dalton transactions : an international journal of inorganic chemistry (19.03.2024)
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Different contributions of chemokine N‐terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3
Szpakowska, Martyna, Nevins, Amanda M, Meyrath, Max, Rhainds, David, D'huys, Thomas, Guité‐Vinet, François, Dupuis, Nadine, Gauthier, Pierre‐Arnaud, Counson, Manuel, Kleist, Andrew, St‐Onge, Geneviève, Hanson, Julien, Schols, Dominique, Volkman, Brian F, Heveker, Nikolaus, Chevigné, Andy
Published in British journal of pharmacology (01.05.2018)
Published in British journal of pharmacology (01.05.2018)
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CXCR4 and ACKR3 binding azamacrocyclic compounds for targeted PET imaging and therapeutic applications in cancer
Renard, Isaline, Nicholson, Kate, D'Huys, Thomas, Burke, Benjamin, Domarkas, Juozas, Hubin, Timothy, Schols, Dominique, Cawthorne, Christopher, Archibald, Steve
Published in The Journal of nuclear medicine (1978) (01.05.2019)
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Published in The Journal of nuclear medicine (1978) (01.05.2019)
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A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
Schoofs, Geert, Van Hout, Anneleen, D'huys, Thomas, Schols, Dominique, Van Loy, Tom
Published in Journal of visualized experiments (10.03.2018)
Published in Journal of visualized experiments (10.03.2018)
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
Claes, Sandra, D'huys, Thomas, Van Hout, Anneleen, Schols, Dominique, Van Loy, Tom
Published in Journal of visualized experiments (20.02.2018)
Published in Journal of visualized experiments (20.02.2018)
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Chelator and linker variation in bis-azamacrocyclic gallium-68 CXCR4 chemokine receptor targeted imaging agents
Renard, Isaline, Burke, Benjamin, Poty, Sophie, D'huys, Thomas, Domarkas, Juozas, Roberts, David, Schols, Dominique, Denat, Franck, Goze, Christine, Cawthorne, Christopher, Archibald, Steve
Published in The Journal of nuclear medicine (1978) (01.05.2018)
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Published in The Journal of nuclear medicine (1978) (01.05.2018)
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Aspartate-Based CXCR4 Chemokine Receptor Binding of Cross-Bridged Tetraazamacrocyclic Copper(II) and Zinc(II) Complexes
Maples, Randall D., Cain, Amy N., Burke, Benjamin P., Silversides, Jon D., Mewis, Ryan E., D'huys, Thomas, Schols, Dominique, Linder, Douglas P., Archibald, Stephen J., Hubin, Timothy J.
Published in Chemistry : a European journal (26.08.2016)
Published in Chemistry : a European journal (26.08.2016)
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A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
Schoofs, Geert, Van Hout, Anneleen, D'huys, Thomas, Schols, Dominique, Van Loy, Tom
Published in Journal of visualized experiments (10.03.2018)
Published in Journal of visualized experiments (10.03.2018)
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
Claes, Sandra, D'huys, Thomas, Van Hout, Anneleen, Schols, Dominique, Van Loy, Tom
Published in Journal of visualized experiments (20.02.2018)
Published in Journal of visualized experiments (20.02.2018)
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