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Heran, Christopher, Morgan, Suzanne, Kasiewski, Charles, Bostwick, Jeffrey, Bentley, Ross, Klein, Scott, Chu, Valeria, Brown, Karen, Colussi, Dennis, Czekaj, Mark, Perrone, Mark, Leadley, Robert
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Published in European journal of pharmacology (18.02.2000)
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Discovery of SARxxxx92, a pan-PIM kinase inhibitor, efficacious in a KG1 tumor model
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Published in Bioorganic & medicinal chemistry letters (01.12.2020)
Published in Bioorganic & medicinal chemistry letters (01.12.2020)
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Discovery of N-substituted 7-azaindoles as Pan-PIM kinases inhibitors – Lead optimization – Part III
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Published in Bioorganic & medicinal chemistry letters (01.02.2019)
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Discovery of N-substituted 7-azaindoles as Pan-PIM kinase inhibitors – Lead series identification – Part II
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Published in Bioorganic & medicinal chemistry letters (15.10.2017)
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콜로니 자극 인자-1 수용체(CSF-1R) 저해제
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Year of Publication 21.03.2018
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Year of Publication 21.03.2018
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Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptase
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Published in Bioorganic & medicinal chemistry letters (02.06.2005)
Published in Bioorganic & medicinal chemistry letters (02.06.2005)
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Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of βII tryptase
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Published in Bioorganic & medicinal chemistry (15.04.2005)
Published in Bioorganic & medicinal chemistry (15.04.2005)
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Optimization of the β-Aminoester class of factor Xa inhibitors. part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity
Guertin, Kevin R, Gardner, Charles J, Klein, Scott I, Zulli, Allison L, Czekaj, Mark, Gong, Yong, Spada, Alfred P, Cheney, Daniel L, Maignan, Sebastian, Guilloteau, Jean-Pierre, Brown, Karen D, Colussi, Dennis J, Chu, Valeria, Heran, Christopher L, Morgan, Suzanne R, Bentley, Ross G, Dunwiddie, Christopher T, Leadley, Robert J, Pauls, Henry W
Published in Bioorganic & medicinal chemistry letters (17.06.2002)
Published in Bioorganic & medicinal chemistry letters (17.06.2002)
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COLONY STIMULATING FACTOR-1 RECEPTOR (CSF-1R) INHIBITORS
Scholte, Andrew, Le, Tieu-Binh, Kane, JR., John L, Liu, Jinyu, Czekaj, Mark, Giese, Barret, Shum, Patrick, Wei, Linli, Kothe, Michael, Patel, Vinod, Barberis, Claude, Ma, Liang, Erdman, Paul, Metz, Markus
Year of Publication 04.07.2024
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Year of Publication 04.07.2024
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Colony stimulating factor-1 receptor (csf-1r) inhibitors
Scholte, Andrew, Kane, John L, Le, Tieu-Binh, Liu, Jinyu, Czekaj, Mark, Giese, Barret, Shum, Patrick, Kothe, Michael, Patel, Vinod, Barberis, Claude, Wei, Limli, Ma, Liang, Erdman, Paul, Metz, Markus
Year of Publication 23.02.2024
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Optimization of the β-aminoester class of factor Xa inhibitors. Part 1: P4 and side-chain modifications for improved in vitro potency
CZEKAJ, Mark, KLEIN, Scott I, CHU, Valeria, LEADLEY, Robert J, DUNWIDDIE, Christopher T, GUERTIN, Kevin R, GARDNER, Charles J, ZULLI, Allison L, PAULS, Henry W, SPADA, Alfred P, CHENEY, Daniel L, BROWN, Karen D, COLUSSI, Dennis J
Published in Bioorganic & medicinal chemistry letters (17.06.2002)
Published in Bioorganic & medicinal chemistry letters (17.06.2002)
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Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of betaII tryptase
Levell, Julian, Astles, Peter, Eastwood, Paul, Cairns, Jennifer, Houille, Olivier, Aldous, Suzanne, Merriman, Gregory, Whiteley, Brian, Pribish, James, Czekaj, Mark, Liang, Guyan, Maignan, Sebastien, Guilloteau, Jean-Pierre, Dupuy, Alain, Davidson, Jane, Harrison, Trevor, Morley, Andrew, Watson, Simon, Fenton, Garry, McCarthy, Clive, Romano, Joseph, Mathew, Rose, Engers, Darren, Gardyan, Michael, Sides, Keith, Kwong, Jennifer, Tsay, Joseph, Rebello, Sam, Shen, Liduo, Wang, Jie, Luo, Yongyi, Giardino, Odessa, Lim, Heng-Keang, Smith, Keith, Pauls, Henry
Published in Bioorganic & medicinal chemistry (15.04.2005)
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Published in Bioorganic & medicinal chemistry (15.04.2005)
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Optimization of the β-Aminoester class of factor Xa inhibitors. part 1: P 4 and side-Chain modifications for improved In vitro potency
Czekaj, Mark, Klein, Scott I, Guertin, Kevin R, Gardner, Charles J, Zulli, Allison L, Pauls, Henry W, Spada, Alfred P, Cheney, Daniel L, Brown, Karen D, Colussi, Dennis J, Chu, Valeria, Leadley, Robert J, Dunwiddie, Christopher T
Published in Bioorganic & medicinal chemistry letters (17.06.2002)
Published in Bioorganic & medicinal chemistry letters (17.06.2002)
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Colony stimulating factor-1 receptor (CSF-1R) inhibitors
WEI, Linli, SHUM, Patrick, KANE JR., John L, BARBERIS, Claude, GIESE, Barret, ERDMAN, Paul, METZ, Markus, SCHOLTE, Andrew, MA, Liang, LIU, Jinyu, CZEKAJ, Mark, KOTHE, Michael, PATEL, Vinod, LE, Tieu-Binh
Year of Publication 23.03.2023
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COLONY STIMULATING FACTOR-1 RECEPTOR (CSF-1R) INHIBITORS
Scholte, Andrew, Le, Tieu-Binh, Kane, JR., John L, Liu, Jinyu, Czekaj, Mark, Giese, Barret, Shum, Patrick, Wei, Linli, Kothe, Michael, Patel, Vinod, Barberis, Claude, Ma, Liang, Erdman, Paul, Metz, Markus
Year of Publication 15.12.2022
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Year of Publication 15.12.2022
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Colony stimulating factor-1 receptor (CSF-1R) inhibitors
SHUM, Patrick, SCHOL, TE, BARBERIS, Claude, GIESE, Barret, ERDMAN, Paul, METZ, Markus, KANE, John L, MA, Liang, LIU, Jinyu, CZEKAJ, Mark, KOTHE, Michael, PATEL, Vinod, LE, Tieubinh
Year of Publication 01.12.2022
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Year of Publication 01.12.2022
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Identification and Initial Structure−Activity Relationships of a Novel Class of Nonpeptide Inhibitors of Blood Coagulation Factor Xa
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Published in Journal of medicinal chemistry (12.02.1998)
Published in Journal of medicinal chemistry (12.02.1998)
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Colony stimulating factor-1 receptor (CSF-1R) inhibitors
Scholte, Andrew, Le, Tieu-Binh, Kane, Jr., John L, Liu, Jinyu, Czekaj, Mark, Giese, Barret, Wei, Linli, Shum, Patrick Wai-Kwok, Kothe, Michael, Patel, Vinod, Barberis, Claude, Ma, Liang, Erdman, Paul, Metz, Markus
Year of Publication 15.03.2022
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Year of Publication 15.03.2022
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Optimization of the beta-aminoester class of factor Xa inhibitors. Part 1: P(4) and side-chain modifications for improved in vitro potency
Czekaj, Mark, Klein, Scott I, Guertin, Kevin R, Gardner, Charles J, Zulli, Allison L, Pauls, Henry W, Spada, Alfred P, Cheney, Daniel L, Brown, Karen D, Colussi, Dennis J, Chu, Valeria, Leadley, Robert J, Dunwiddie, Christopher T
Published in Bioorganic & medicinal chemistry letters (17.06.2002)
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Published in Bioorganic & medicinal chemistry letters (17.06.2002)
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Constrained β-alanine based GpIIb/IIIa antagonists
Klein, Scott I, Czekaj, Mark, Molino, Bruce F, Chu, Valeria
Published in Bioorganic & medicinal chemistry letters (08.07.1997)
Published in Bioorganic & medicinal chemistry letters (08.07.1997)
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