Loading…
METABOLISM OF MELATONIN BY HUMAN CYTOCHROMES P450
Ma, Xiaochao, Idle, Jeffrey R., Krausz, Kristopher W., Gonzalez, Frank J.
Published in Drug metabolism and disposition (01.04.2005)
Published in Drug metabolism and disposition (01.04.2005)
Get full text
Journal Article
Loading…
AUTOINDUCTION OF MKC-963 [(R)-1-(1-CYCLOHEXYLETHYLAMINO)-4-PHENYLPHTHALAZINE] METABOLISM IN HEALTHY VOLUNTEERS AND ITS RETROSPECTIVE EVALUATION USING PRIMARY HUMAN HEPATOCYTES AND CDNA-EXPRESSED ENZYMES
Shimizu, Toshiyuki, Akimoto, Kei, Yoshimura, Takuya, Niwa, Takuro, Kobayashi, Kaoru, Tsunoo, Michio, Chiba, Kan
Published in Drug metabolism and disposition (01.06.2006)
Published in Drug metabolism and disposition (01.06.2006)
Get full text
Journal Article
Loading…
Exploring the Use of Serum-Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Hepatic Cytochromes P450 and Organic Anion Transporting Polypeptides
Rodrigues, A David, van Dyk, Madelé, Sorich, Michael J, Fahmy, Alia, Useckaite, Zivile, Newman, Lauren A, Kapetas, Asha J, Mounzer, Reham, Wood, Linda S, Johnson, Jillian G, Rowland, Andrew
Published in Clinical pharmacology and therapeutics (01.07.2021)
Published in Clinical pharmacology and therapeutics (01.07.2021)
Get more information
Journal Article
Loading…
Comparative Intra‐Subject Analysis of Gene Expression and Protein Abundance of Major and Minor Drug Metabolizing Enzymes in Healthy Human Jejunum and Liver
Wenzel, Christoph, Lapczuk‐Romanska, Joanna, Malinowski, Damian, Ostrowski, Marek, Drozdzik, Marek, Oswald, Stefan
Published in Clinical pharmacology and therapeutics (01.02.2024)
Published in Clinical pharmacology and therapeutics (01.02.2024)
Get full text
Journal Article
Loading…
Distribution Characteristics and Impacting Factors of Drug CYP Enzymes and Transporters in the Gastrointestinal Tract of Chinese Healthy Subjects
Zhang, Miao, Zhang, Lei, Suo, Baojun, Wei, Yudong, Xu, Yue, Jiang, Muhan, Dong, Jing, Li, Xiaodong, Song, Zhiqiang, Liu, Dongyang
Published in Clinical pharmacology and therapeutics (01.03.2025)
Published in Clinical pharmacology and therapeutics (01.03.2025)
Get more information
Journal Article
Loading…
Loading…
Expression of clinically relevant drug‐metabolizing enzymes along the human intestine and their correlation to drug transporters and nuclear receptors: An intra‐subject analysis
Fritz, Anja, Busch, Diana, Lapczuk, Joanna, Ostrowski, Marek, Drozdzik, Marek, Oswald, Stefan
Published in Basic & clinical pharmacology & toxicology (01.03.2019)
Published in Basic & clinical pharmacology & toxicology (01.03.2019)
Get full text
Journal Article
Loading…
CYP4F2 genetic variant alters required warfarin dose
Caldwell, Michael D., Awad, Tarif, Johnson, Julie A., Gage, Brian F., Falkowski, Mat, Gardina, Paul, Hubbard, Jason, Turpaz, Yaron, Langaee, Taimour Y., Eby, Charles, King, Cristi R., Brower, Amy, Schmelzer, John R., Glurich, Ingrid, Vidaillet, Humberto J., Yale, Steven H., Qi Zhang, Kai, Berg, Richard L., Burmester, James K.
Published in Blood (15.04.2008)
Published in Blood (15.04.2008)
Get full text
Journal Article
Loading…
Loading…
Cytochrome P450 phenotyping using the Geneva cocktail improves metabolic capacity prediction in a hospitalized patient population
Gloor, Yvonne S., Mouterde, Médéric, Terrier, Jean, Lenoir, Camille, Gosselin, Pauline, Rollason, Victoria, Reny, Jean‐Luc, Boukouvala, Sotiria, Al‐Yahyaee, Said, Yimer, Getnet, Černý, Viktor, Poloni, Estella S., Samer, Caroline F., Daali, Youssef
Published in British journal of clinical pharmacology (01.05.2025)
Published in British journal of clinical pharmacology (01.05.2025)
Get full text
Journal Article
Loading…
Elucidating the Metabolism of Chiral PCB95 in Wildtype and Transgenic Mouse Models with Altered Cytochrome P450 Enzymes Using Intestinal Content Screening
Li, Xueshu, Bullert, Amanda J., Gautam, Binita, Han, Weiguo, Yang, Weizhu, Zhang, Qing-Yu, Ding, Xinxin, Lehmler, Hans-Joachim
Published in Chemical research in toxicology (16.12.2024)
Published in Chemical research in toxicology (16.12.2024)
Get full text
Journal Article
Loading…
Evolutionary history of Tibetans inferred from whole-genome sequencing
Hu, Hao, Petousi, Nayia, Glusman, Gustavo, Yu, Yao, Bohlender, Ryan, Tashi, Tsewang, Downie, Jonathan M., Roach, Jared C., Cole, Amy M., Lorenzo, Felipe R., Rogers, Alan R., Brunkow, Mary E., Cavalleri, Gianpiero, Hood, Leroy, Alpatty, Sama M., Prchal, Josef T., Jorde, Lynn B., Robbins, Peter A., Simonson, Tatum S., Huff, Chad D.
Published in PLoS genetics (27.04.2017)
Published in PLoS genetics (27.04.2017)
Get full text
Journal Article
Loading…
A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose
Takeuchi, Fumihiko, McGinnis, Ralph, Bourgeois, Stephane, Barnes, Chris, Eriksson, Niclas, Soranzo, Nicole, Whittaker, Pamela, Ranganath, Venkatesh, Kumanduri, Vasudev, McLaren, William, Holm, Lennart, Lindh, Jonatan, Rane, Anders, Wadelius, Mia, Deloukas, Panos
Published in PLoS genetics (01.03.2009)
Published in PLoS genetics (01.03.2009)
Get full text
Journal Article
Loading…
Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach
Trégouët, David-Alexandre, Heath, Simon, Saut, Noémie, Biron-Andreani, Christine, Schved, Jean-François, Pernod, Gilles, Galan, Pilar, Drouet, Ludovic, Zelenika, Diana, Juhan-Vague, Irène, Alessi, Marie-Christine, Tiret, Laurence, Lathrop, Mark, Emmerich, Joseph, Morange, Pierre-Emmanuel
Published in Blood (21.05.2009)
Published in Blood (21.05.2009)
Get full text
Journal Article
Loading…
Loading…
Cytochrome P450 Genetic Polymorphisms and the Response to Prasugrel: Relationship to Pharmacokinetic, Pharmacodynamic, and Clinical Outcomes
Mega, Jessica L., Close, Sandra L., Wiviott, Stephen D., Shen, Lei, Hockett, Richard D., Brandt, John T., Walker, Joseph R., Antman, Elliott M., Macias, William L., Braunwald, Eugene, Sabatine, Marc S.
Published in Circulation (New York, N.Y.) (19.05.2009)
Published in Circulation (New York, N.Y.) (19.05.2009)
Get full text
Journal Article
Loading…
Pharmacokinetics and pharmacodynamics of cytochrome P450 inhibitors for HIV treatment
Gong, Yuqing, Haque, Sanjana, Chowdhury, Pallabita, Cory, Theodore J, Kodidela, Sunitha, Yallapu, Murali M, Norwood, John M, Kumar, Santosh
Published in Expert opinion on drug metabolism & toxicology (04.05.2019)
Published in Expert opinion on drug metabolism & toxicology (04.05.2019)
Get more information
Journal Article
Loading…
Activity and mRNA expression levels of selected cytochromes P450 in various sections of the human small intestine
Clermont, Valérie, Grangeon, Alexia, Barama, Azemi, Turgeon, Jacques, Lallier, Michel, Malaise, Jacques, Michaud, Veronique
Published in British journal of clinical pharmacology (01.06.2019)
Published in British journal of clinical pharmacology (01.06.2019)
Get full text
Journal Article
Loading…
Loading…
Analysis of Genetic Variation in CYP450 Genes for Clinical Implementation
Goh, Liuh Ling, Lim, Chia Wei, Sim, Wey Cheng, Toh, Li Xian, Leong, Khai Pang
Published in PloS one (03.01.2017)
Published in PloS one (03.01.2017)
Get full text
Journal Article