Comparisons in vitro, ex vivo, and in vivo of the actions of seven structurally diverse inhibitors of angiotensin converting enzyme (ACE)
Cushman, DW, Wang, FL, Fung, WC, Grover, GJ, Harvey, CM, Scalese, RJ, Mitch, SL, DeForrest, JM
Published in British journal of clinical pharmacology (1989)
Published in British journal of clinical pharmacology (1989)
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Journal Article
Conference Proceeding
Differentiation of angiotensin-converting enzyme (ACE) inhibitors by their selective inhibition of ACE in physiologically important target organs
Cushman, D W, Wang, F L, Fung, W C, Harvey, C M, DeForrest, J M
Published in American journal of hypertension (01.04.1989)
Published in American journal of hypertension (01.04.1989)
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Effects of different angiotensin-converting enzyme (ACE) inhibitors on ischemic isolated rat hearts: relationship between cardiac ACE inhibition and cardioprotection
GROVER, G. J, SLEPH, P. G, DZWONCZYK, S, WANG, P, WENDY FUNG, TOBIAS, F, CUSHMAN, D. W
Published in The Journal of pharmacology and experimental therapeutics (01.06.1991)
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Published in The Journal of pharmacology and experimental therapeutics (01.06.1991)
Journal Article
Angiotensin-converting enzyme inhibitors. Mercaptan, carboxyalkyl dipeptide, and phosphinic acid inhibitors incorporating 4-substituted prolines
Krapcho, John, Turk, Chester, Cushman, David W, Powell, James R, DeForrest, Jack M, Spitzmiller, Ervin R, Karanewsky, Donald S, Duggan, Mark, Rovnyak, George
Published in Journal of medicinal chemistry (01.06.1988)
Published in Journal of medicinal chemistry (01.06.1988)
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Design of novel inhibitors of aminopeptidases. Synthesis of peptide-derived diamino thiols and sulfur replacement analogs of bestatin
Gordon, E. M, Godfrey, J. D, Delaney, N. G, Asaad, M. M, Von Langen, D, Cushman, D. W
Published in Journal of medicinal chemistry (01.11.1988)
Published in Journal of medicinal chemistry (01.11.1988)
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(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme (ACE). 1. Discovery of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline, a novel orally active inhibitor of ACE
Karanewsky, Donald S, Badia, Michael C, Cushman, David W, DeForrest, Jack M, Dejneka, Tamara, Loots, Melanie J, Perri, Maria G, Petrillo, Edward W, Powell, James R
Published in Journal of medicinal chemistry (01.01.1988)
Published in Journal of medicinal chemistry (01.01.1988)
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(Phosphinyloxy)acyl amino acid inhibitors of angiotensin converting enzyme. 2. Terminal amino acid analogs of (S)-1-[6-amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline
Karanewsky, Donald S, Badia, Michael C, Cushman, David W, DeForrest, Jack M, Dejneka, Tamara, Lee, Ving G, Loots, Melanie J, Petrillo, Edward W
Published in Journal of medicinal chemistry (01.05.1990)
Published in Journal of medicinal chemistry (01.05.1990)
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Journal Article
Preclinical pharmacology of zofenopril, an inhibitor of angiotensin I converting enzyme
DeForrest, J M, Waldron, T L, Krapcho, J, Turk, C, Rubin, B, Powell, J R, Cushman, D W, Petrillo, E W
Published in Journal of cardiovascular pharmacology (01.06.1989)
Published in Journal of cardiovascular pharmacology (01.06.1989)
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Development and design of specific inhibitors of angiotensin-converting enzyme
Cushman, David W., Cheung, Hong Son, Sabo, Emily F., Ondetti, Miguel A.
Published in The American journal of cardiology (21.04.1982)
Published in The American journal of cardiology (21.04.1982)
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Rat brain enkephalinase: characterization of the active site using mercaptopropanoyl amino acid inhibitors, and comparison with angiotensin-converting enzyme
Gordon, E M, Cushman, D W, Tung, R, Cheung, H S, Wang, F L, Delaney, N G
Published in Life sciences (1973) (1983)
Published in Life sciences (1973) (1983)
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