Search Results - "Curtis HARWIG" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Abstract 1871: Development of pelorol analogues to activate the SHIP1 lipid phosphatase; a novel paradigm to suppress B-cell receptor signaling in human B-cell cancers

Abstract 1871: Development of pelorol analogues to activate the SHIP1 lipid phosphatase; a novel paradigm to suppress B-cell receptor signaling in human B-cell cancers

by Packham, Graham, Lemm, Elizabeth, Valle-Argos, Beatriz, Smith, Lindsay, Weston-Bell, Nichola, Stevenson, Freda, Carter, Matthew J., Cragg, Mark S., Forconi, Francesco, Steele, Andrew J., Cross, Jennifer, Harwig, Curtis, Lenz, Georg, Mackenzie, Lloyd, Klener, Pavel
Published in Cancer research (Chicago, Ill.) (01.07.2018)

Get full text

Journal Article

Chemical Activation of the SHIP1 Inositol Lipid Phosphatase: A Novel Therapeutic Strategy to Suppress B-Cell Receptor Signaling and CXCR4 Expression in Malignant Human B Cells

Chemical Activation of the SHIP1 Inositol Lipid Phosphatase: A Novel Therapeutic Strategy to Suppress B-Cell Receptor Signaling and CXCR4 Expression in Malignant Human B Cells

by Packham, Graham, Valle-Argos, Beatriz, Lemm, Elizabeth, Smith, Lindsay D, Weston-Bell, Nicola J, Gebreselassie, Yohannes, Steele, Andrew J, Stevenson, Freda K, Cragg, Mark S, Forconi, Francesco, Cross, Jennifer, Harwig, Curtis, Mackenzie, Lloyd
Published in Blood (02.12.2016)

Get full text

Journal Article

Taxamycins: a new enediyne family with synthetic and biological potential

Taxamycins: a new enediyne family with synthetic and biological potential

by Lu, Yee-Fung, Harwig, Curtis W, Fallis, Alex G
Published in Canadian journal of chemistry (01.12.1995)

Get full text

Journal Article

Synthesis and characterization of 2,6-difluoro-4-carboxyphenylboronic acid and a biotin derivative thereof as captors of anionic aqueous [ 18F]-fluoride for the preparation of [ 18F/ 19F]-labeled aryltrifluoroborates with high kinetic stability

Synthesis and characterization of 2,6-difluoro-4-carboxyphenylboronic acid and a biotin derivative thereof as captors of anionic aqueous [ 18F]-fluoride for the preparation of [ 18F/ 19F]-labeled aryltrifluoroborates with high kinetic stability

by Harwig, Curtis W., Ting, Richard, Adam, Michael J., Ruth, Thomas J., Perrin, David M.
Published in Tetrahedron letters (05.05.2008)

Get full text

Journal Article

Synthesis of SHIP1-Activating Analogs of the Sponge Meroterpenoid Pelorol

Synthesis of SHIP1-Activating Analogs of the Sponge Meroterpenoid Pelorol

by Meimetis, Labros G., Nodwell, Matt, Yang, Lu, Wang, Xiaoxia, Wu, Joyce, Harwig, Curtis, Stenton, Grant R., Mackenzie, Lloyd F., MacRury, Thomas, Patrick, Brian O., Ming-Lum, Andrew, Ong, Christopher J., Krystal, Gerald, Mui, Alice L. -F., Andersen, Raymond J.
Published in European journal of organic chemistry (01.09.2012)

Get full text

Journal Article

Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication

Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication

by Skerlj, Renato, Bridger, Gary, McEachern, Ernie, Harwig, Curtis, Smith, Chris, Wilson, Trevor, Veale, Duane, Yee, Helen, Crawford, Jason, Skupinska, Krystyna, Wauthy, Rossana, Yang, Wen, Zhu, Yongbao, Bogucki, David, Di Fluri, Maria, Langille, Jonathon, Huskens, Dana, De Clercq, Erik, Schols, Dominique
Published in Bioorganic & medicinal chemistry letters (01.01.2011)

Get full text

Journal Article

Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 1. Effects on inflammatory cell activation and chemotaxis

Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 1. Effects on inflammatory cell activation and chemotaxis

by Stenton, Grant R, Mackenzie, Patrick Tam, Lloyd F, Cross, Jennifer L, Harwig, Curtis, Raymond, Jeffrey, Toews, Judy, Wu, Joyce, Ogden, Nancy, MacRury, Thomas, Szabo, Csaba
Published in British journal of pharmacology (25.02.2013)

Get full text

Journal Article

Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 2. Efficacy studies in allergic and pulmonary inflammation models

Characterization of AQX-1125, a small-molecule SHIP1 activator: Part 2. Efficacy studies in allergic and pulmonary inflammation models

by Stenton, Grant R, Mackenzie, Patrick Tam, Lloyd F, Cross, Jennifer L, Harwig, Curtis, Raymond, Jeffrey, Toews, Judy, Chernoff, David, MacRury, Thomas, Szabo, Csaba
Published in British journal of pharmacology (25.02.2013)

Get full text

Journal Article

Design of Substituted lmidazolidinylpiperidinylbenzoic Acids as Chemokine Receptor 5 Antagonists: Potent Inhibitors of R5 HIV-1 Replication

Design of Substituted lmidazolidinylpiperidinylbenzoic Acids as Chemokine Receptor 5 Antagonists: Potent Inhibitors of R5 HIV-1 Replication

by Skerlj, Renato, Bridge, Gary, Zhou, Yuanxi, Bourque, Elyse, McEachern, Ernest, Metz, Markus, Harwig, Curtis, Li, Tong-Shuang, Yang, Wen, Bogucki, David, Zhu, Yongbao, Langille, Jonathan, Veale, Duane, Ba, Tuya, Bey, Michael, Baird, Ian, Kaller, Alan, Krumpak, Maria, Leitch, David, Satori, Michael, Vocadlo, Krystyna, Guay, Danielle, Nan, Susan, Yee, Helen, Crawford, Jason, Chen, Gang, Wilson, Trevor, Carpenter, Bryon, Gauthier, David, MacFarland, Ron, Mosi, Renee, Bodart, Veronique, Wong, Rebecca, Fricker, Simon, Schols, Dominique
Published in Journal of medicinal chemistry (24.10.2013)

Get full text

Journal Article

Design of Substituted Imidazolidinylpiperidinylbenzoic Acids as Chemokine Receptor 5 Antagonists: Potent Inhibitors of R5 HIV‑1 Replication

Design of Substituted Imidazolidinylpiperidinylbenzoic Acids as Chemokine Receptor 5 Antagonists: Potent Inhibitors of R5 HIV‑1 Replication

by Skerlj, Renato, Bridger, Gary, Zhou, Yuanxi, Bourque, Elyse, McEachern, Ernest, Metz, Markus, Harwig, Curtis, Li, Tong-Shuang, Yang, Wen, Bogucki, David, Zhu, Yongbao, Langille, Jonathan, Veale, Duane, Ba, Tuya, Bey, Michael, Baird, Ian, Kaller, Alan, Krumpak, Maria, Leitch, David, Satori, Michael, Vocadlo, Krystyna, Guay, Danielle, Nan, Susan, Yee, Helen, Crawford, Jason, Chen, Gang, Wilson, Trevor, Carpenter, Bryon, Gauthier, David, MacFarland, Ron, Mosi, Renee, Bodart, Veronique, Wong, Rebecca, Fricker, Simon, Schols, Dominique
Published in Journal of medicinal chemistry (24.10.2013)

Get full text

Journal Article

Prospective CCR5 Small Molecule Antagonist Compound Design Using a Combined Mutagenesis/Modeling Approach

Prospective CCR5 Small Molecule Antagonist Compound Design Using a Combined Mutagenesis/Modeling Approach

by Metz, Markus, Bourque, Elyse, Labrecque, Jean, Danthi, Sanjay J, Langille, Jonathan, Harwig, Curtis, Yang, Wen, Darkes, Marilyn C, Lau, Gloria, Santucci, Zefferino, Bridger, Gary J, Schols, Dominique, Fricker, Simon P, Skerlj, Renato T
Published in Journal of the American Chemical Society (19.10.2011)

Get full text

Journal Article

Taxamycin Studies: CrCl(2)/NiCl(2)-Mediated Cyclizations and Unusual SeO(2) Oxidations

Taxamycin Studies: CrCl(2)/NiCl(2)-Mediated Cyclizations and Unusual SeO(2) Oxidations

by Harwig, Curtis W., Py, Sandrine, Fallis, Alex G.
Published in Journal of organic chemistry (14.11.1997)

Get full text

Journal Article

SHIP1 MODULATOR AND METHOD RELATED THERETO

SHIP1 MODULATOR AND METHOD RELATED THERETO

by RAYMOND JEFFERY R, LLOYD F MACKENZIE, THOMAS B MACRURY, VLADIMIR KHLEBNIKOV, SHAN RUDONG, CURTIS HARWIG, DAVID BOGUCKI, JEREMY D PETTIGREW
Year of Publication 30.08.2018

Get full text

Patent

Design of novel CXCR4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication

Design of novel CXCR4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication

by Skerlj, Renato, Bridger, Gary, McEachern, Ernest, Harwig, Curtis, Smith, Chris, Kaller, Alan, Veale, Duane, Yee, Helen, Skupinska, Krystyna, Wauthy, Rossana, Wang, Letian, Baird, Ian, Zhu, Yongbao, Burrage, Kate, Yang, Wen, Sartori, Michael, Huskens, Dana, Clercq, Erik De, Schols, Dominique
Published in Bioorganic & medicinal chemistry letters (01.03.2011)

Get full text

Journal Article

Design and synthesis of pyridin-2-ylmethylaminopiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication

Design and synthesis of pyridin-2-ylmethylaminopiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication

by Skerlj, Renato, Bridger, Gary, Zhou, Yuanxi, Bourque, Elyse, McEachern, Ernest, Langille, Jonathan, Harwig, Curtis, Veale, Duane, Yang, Wen, Li, Tongshong, Zhu, Yongbao, Bey, Michael, Baird, Ian, Sartori, Michael, Metz, Markus, Mosi, Renee, Nelson, Kim, Bodart, Veronique, Wong, Rebecca, Fricker, Simon, Mac Farland, Ron, Huskens, Dana, Schols, Dominique
Published in Bioorganic & medicinal chemistry letters (01.12.2011)

Get full text

Journal Article

AMD070, a CXCR4 Chemokine Receptor Antagonist: Practical Large-Scale Laboratory Synthesis

AMD070, a CXCR4 Chemokine Receptor Antagonist: Practical Large-Scale Laboratory Synthesis

by Crawford, Jason B, Chen, Gang, Gauthier, David, Wilson, Trevor, Carpenter, Bryon, Baird, Ian R, McEachern, Ernie, Kaller, Alan, Harwig, Curtis, Atsma, Bem, Skerlj, Renato T, Bridger, Gary J
Published in Organic process research & development (19.09.2008)

Get full text

Journal Article

Substituent Effects on Aryltrifluoroborate Solvolysis in Water: Implications for Suzuki−Miyaura Coupling and the Design of Stable 18 F-Labeled Aryltrifluoroborates for Use in PET Imaging

Substituent Effects on Aryltrifluoroborate Solvolysis in Water: Implications for Suzuki−Miyaura Coupling and the Design of Stable 18 F-Labeled Aryltrifluoroborates for Use in PET Imaging

by Ting, Richard, Harwig, Curtis W., Lo, Justin, Li, Ying, Adam, Michael J., Ruth, Thomas J., Perrin, David M.
Published in Journal of organic chemistry (01.06.2008)

Get full text

Journal Article

Mitigating hERG Inhibition: Design of Orally Bioavailable CCR5 Antagonists as Potent Inhibitors of R5 HIV-1 Replication

Mitigating hERG Inhibition: Design of Orally Bioavailable CCR5 Antagonists as Potent Inhibitors of R5 HIV-1 Replication

by Skerlj, Renato, Bridger, Gary, Zhou, Yuanxi, Bourque, Elyse, McEachern, Ernest, Danthi, Sanjay, Langille, Jonathan, Harwig, Curtis, Veale, Duane, Carpenter, Bryon, Ba, Tuya, Bey, Michael, Baird, Ian, Wilson, Trevor, Metz, Markus, MacFarland, Ron, Mosi, Renee, Bodart, Veronique, Wong, Rebecca, Fricker, Simon, Huskens, Dana, Schols, Dominique
Published in ACS medicinal chemistry letters (08.03.2012)

Get full text

Journal Article

18F-click labeling of a bombesin antagonist with an alkyne-18F-ArBF3 -: in vivo PET imaging of tumors expressing the GRP-receptor

18F-click labeling of a bombesin antagonist with an alkyne-18F-ArBF3 -: in vivo PET imaging of tumors expressing the GRP-receptor

by Li, Ying, Liu, Zhibo, Harwig, Curtis W, Pourghiasian, Maral, Lau, Joseph, Lin, Kuo-Shyan, Schaffer, Paul, Benard, Francois, Perrin, David M
Published in American journal of nuclear medicine and molecular imaging (05.01.2013)

Get full text

Journal Article

(18)F-click labeling of a bombesin antagonist with an alkyne-(18)F-ArBF(3) (-): in vivo PET imaging of tumors expressing the GRP-receptor

(18)F-click labeling of a bombesin antagonist with an alkyne-(18)F-ArBF(3) (-): in vivo PET imaging of tumors expressing the GRP-receptor

by Li, Ying, Liu, Zhibo, Harwig, Curtis W, Pourghiasian, Maral, Lau, Joseph, Lin, Kuo-Shyan, Schaffer, Paul, Benard, Francois, Perrin, David M
Published in American journal of nuclear medicine and molecular imaging (2013)

Get full text

Journal Article

[1]
Prev
1
2
3
4
5
6
7
8
9
10
11
Next
[18]