Investigation of Synthetic Routes to a Key Benzopyran Intermediate of a 5HT4 Agonist
Rassias, Geracimos, Stevenson, Neil G, Curtis, Neil R, Northall, John M, Gray, Matthew, Prodger, Jeremy C, Walker, Andrew J
Published in Organic process research & development (15.01.2010)
Published in Organic process research & development (15.01.2010)
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Synthesis of (+)-Obtusenyne
Mak, S. Y. Frankie, Curtis, Neil R., Payne, Andrew N., Congreve, Miles S., Wildsmith, Andrew J., Francis, Craig L., Davies, John E., Pascu, Sofia I., Burton, Jonathan W., Holmes, Andrew B.
Published in Chemistry : a European journal (17.03.2008)
Published in Chemistry : a European journal (17.03.2008)
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Selective Continuous Flow Iodination Guided by Direct Spectroscopic Observation of Equilibrating Aryl Lithium Regioisomers
Dunn, Anna L, Leitch, David C, Journet, Michel, Martin, Michael, Tabet, Elie A, Curtis, Neil R, Williams, Glynn, Goss, Charles, Shaw, Tony, O’Hare, Bernie, Wade, Charles, Toczko, Matthew A, Liu, Peng
Published in Organometallics (14.01.2019)
Published in Organometallics (14.01.2019)
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Orally Efficacious NR2B-Selective NMDA Receptor Antagonists
Claiborne, Christopher F, McCauley, John A, Libby, Brian E, Curtis, Neil R, Diggle, Helen J, Kulagowski, Janusz J, Michelson, Stuart R, Anderson, Kenneth D, Claremon, David A, Freidinger, Roger M, Bednar, Rodney A, Mosser, Scott D, Gaul, Stanley L, Connolly, Thomas M, Condra, Cindra L, Bednar, Bohumil, Stump, Gary L, Lynch, Joseph J, Macaulay, Alison, Wafford, Keith A, Koblan, Kenneth S, Liverton, Nigel J
Published in Bioorganic & medicinal chemistry letters (24.02.2003)
Published in Bioorganic & medicinal chemistry letters (24.02.2003)
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Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor
Liddle, John, Atkinson, Francis L., Barker, Michael D., Carter, Paul S., Curtis, Neil R., Davis, Rob P., Douault, Clement, Dickson, Marion C., Elwes, Dorothy, Garton, Neil S., Gray, Matthew, Hayhow, Thomas G., Hobbs, Clare I., Jones, Emma, Leach, Stuart, Leavens, Karen, Lewis, Huw D., McCleary, Scott, Neu, Margarete, Patel, Vipulkumar K., Preston, Alex G.S., Ramirez-Molina, Cesar, Shipley, Tracy J., Skone, Philip A., Smithers, Nick, Somers, Donald O., Walker, Ann L., Watson, Robert J., Weingarten, Gordon G.
Published in Bioorganic & medicinal chemistry letters (15.10.2011)
Published in Bioorganic & medicinal chemistry letters (15.10.2011)
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Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor
Leeson, Paul D, Baker, Raymond, Carling, Robert W, Curtis, Neil R, Moore, Kevin W, Williams, Brian J, Foster, Alan C, Donald, Angus E, Kemp, John A, Marshall, George R
Published in Journal of medicinal chemistry (01.04.1991)
Published in Journal of medicinal chemistry (01.04.1991)
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3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine: An Antagonist with High Affinity and Selectivity for the Human Dopamine D4 Receptor
Kulagowski, Janusz J, Broughton, Howard B, Curtis, Neil R, Mawer, Ian M, Ridgill, Mark P, Baker, Raymond, Emms, Frances, Freedman, Stephen B, Marwood, Rosemarie, Patel, Shil, Patel, Smita, Ragan, C. Ian, Leeson, Paul D
Published in Journal of medicinal chemistry (10.05.1996)
Published in Journal of medicinal chemistry (10.05.1996)
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3'-(Arylmethyl)- and 3'-(Aryloxy)-3-phenyl-4-hydroxyquinolin- 2(1H)-ones: Orally Active Antagonists of the Glycine Site on the NMDA Receptor
Kulagowski, Janusz J, Baker, Raymond, Curtis, Neil R, Mawer, Ian M, Moseley, Angela M, Ridgill, Mark P, Rowley, Michael, Stansfield, Ian, Leeson, Paul D
Published in Journal of medicinal chemistry (01.05.1994)
Published in Journal of medicinal chemistry (01.05.1994)
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A Flow Process Built upon a Batch Foundation-Preparation of a Key Amino Alcohol Intermediate via Multistage Continuous Synthesis
Lim, John Jin, Arrington, Kenneth, Dunn, Anna L., Leitch, David C., Andrews, Ian, Curtis, Neil R., Hughes, Mark J., Tray, Daniel R., Wade, Charles E., Whiting, Matthew P., Goss, Charles, Liu, Yangmu Chloe, Roesch, Brian M.
Published in Organic process research & development (16.10.2020)
Published in Organic process research & development (16.10.2020)
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Investigation of Synthetic Routes to a Key Benzopyran Intermediate of a 5HT 4 Agonist
Rassias, Geracimos, Stevenson, Neil G., Curtis, Neil R., Northall, John M., Gray, Matthew, Prodger, Jeremy C., Walker, Andrew J.
Published in Organic process research & development (15.01.2010)
Published in Organic process research & development (15.01.2010)
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A synthesis of (+)-obtusenyne
Mak, SYF, Curtis, NR, Payne, AN, Congreve, MS, Francis, CL, Burton, JW, Holmes, AB
Published in Synthesis (Stuttgart) (01.12.2005)
Published in Synthesis (Stuttgart) (01.12.2005)
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