Discovery of Small-Molecule Human Immunodeficiency Virus Type 1 Entry Inhibitors That Target the gp120-Binding Domain of CD4
YANG, Quan-En, STEPHEN, Andrew G, FISHER, Robert J, SHOEMAKER, Robert H, SEI, Shizuko, ADELSBERGER, Joseph W, ROBERTS, Paula E, WEIMIN ZHU, CURRENS, Michael J, YAXIONG FENG, CRISE, Bruce J, GORELICK, Robert J, REIN, Alan R
Published in Journal of Virology (01.05.2005)
Published in Journal of Virology (01.05.2005)
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Discovery and preliminary SAR of bisbenzylisoquinoline alkaloids as inducers of C/EBPα
Klausmeyer, Paul, McCloud, Thomas G., Scudiero, Dominic A., Currens, Michael J., Cardellina II, John H., Shoemaker, Robert H.
Published in Bioorganic & medicinal chemistry (01.08.2012)
Published in Bioorganic & medicinal chemistry (01.08.2012)
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Chemical library screen for novel inhibitors of Kaposi's sarcoma-associated herpesvirus processive DNA synthesis
Dorjsuren, Dorjbal, Burnette, Angela, Gray, Glenn N., Chen, Xulin, Zhu, Weimin, Roberts, Paula E., Currens, Michael J., Shoemaker, Robert H., Ricciardi, Robert P., Sei, Shizuko
Published in Antiviral research (2006)
Published in Antiviral research (2006)
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Analysis of the Interaction between the HIV-Inactivating Protein Cyanovirin-N and Soluble Forms of the Envelope Glycoproteins gp120 and gp41
O'Keefe, Barry R., Shenoy, Shilpa R., Xie, Dong, Zhang, Wentao, Muschik, Jeffrey M., Currens, Michael J., Chaiken, Irwin, Boyd, Michael R.
Published in Molecular pharmacology (01.11.2000)
Published in Molecular pharmacology (01.11.2000)
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Application of high-throughput, molecular-targeted screening to anticancer drug discovery
Shoemaker, Robert H, Scudiero, Dominic A, Melillo, Giovanni, Currens, Michael J, Monks, Anne P, Rabow, Alfred A, Covell, David G, Sausville, Edward A
Published in Current topics in medicinal chemistry (01.03.2002)
Published in Current topics in medicinal chemistry (01.03.2002)
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Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines
SCUDIERO, D. A, SHOEMAKER, R. H, PAULL, K. D, MONKS, A, TIERNEY, S, NOFZIGER, T. H, CURRENS, M. J, SENIFF, D, BOYD, M. R
Published in Cancer research (Chicago, Ill.) (01.09.1988)
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Published in Cancer research (Chicago, Ill.) (01.09.1988)
Journal Article
RSK2 Binding Models Delineate Key Features for Activity
Gussio, Rick, Currens, Michael J, Scudiero, Dominic A, Smith, Jeffrey A, Lannigan, Deborah A, Shoemaker, Robert H, Zaharevitz, Dan W, Nguyen, Tam Luong
Published in Journal of chemical and pharmaceutical research (2010)
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Published in Journal of chemical and pharmaceutical research (2010)
Journal Article
Isolation and Characterization of Myrianthus holstii Lectin, a Potent HIV-1 Inhibitory Protein from the Plant Myrianthus holstii
Charan, Romila D, Munro, Murray H. G, O'Keefe, Barry R, Sowder, Raymond C, McKee, Tawnya C, Currens, Michael J, Pannell, Lewis K, Boyd, Michael R
Published in Journal of natural products (Washington, D.C.) (01.08.2000)
Published in Journal of natural products (Washington, D.C.) (01.08.2000)
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HIV inhibitory natural products. Part 7. The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum. [Erratum to document cited in CA117(11):108101g]
Kashman, Yoel, Gustafson, Kirk R, Fuller, Richard W, Cardellina, John H, McMahon, James B, Currens, Michael J, Buckheit, Robert W, Hughes, Stephen H, Cragg, Gordon M, Boyd, Michael R
Published in Journal of medicinal chemistry (01.04.1993)
Published in Journal of medicinal chemistry (01.04.1993)
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Journal Article
HIV inhibitory natural products. Part 7. The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum
Kashman, Yoel, Gustafson, Kirk R, Fuller, Richard W, Cardellina, John H, McMahon, James B, Currens, Michael J, Buckheit, Robert W, Hughes, Stephen H, Cragg, Gordon M, Boyd, Michael R
Published in Journal of medicinal chemistry (01.07.1992)
Published in Journal of medicinal chemistry (01.07.1992)
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Journal Article
A Reinvestigation of Maprounea Triterpenes
Beutler, John A, Kashman, Yoel, Tischler, Mark, Cardellina, John H, Gray, Glenn N, Currens, Michael J, Wall, Monroe E, Wani, Mansukh C, Boyd, Michael R
Published in Journal of natural products (Washington, D.C.) (01.07.1995)
Published in Journal of natural products (Washington, D.C.) (01.07.1995)
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Journal Article
Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development
BOYD, M. R, GUSTAFSON, K. R, CURRENS, M. J, CARDELLINA, J. H, BUCKHEIT, R. W, NARA, P. L, PANNELL, L. K, SOWDER, R. C, HENDERSON, L. E, MCMAHON, J. B, SHOEMAKER, R. H, O'KEEFE, B. R, MORI, T, GULAKOWSKI, R. J, WU, L, RIVERA, M. I, LAURENCOT, C. M
Published in Antimicrobial Agents and Chemotherapy (01.07.1997)
Published in Antimicrobial Agents and Chemotherapy (01.07.1997)
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The calanolides, a novel HIV-inhibitory class of Coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum
KASHMAN, Y, GUSTAFSON, K. R, FULLER, R. W, CARDELLINA, J. H, MCMAHON, J. B, CURRENS, M. J, BUCKHEIT, R. W, HUGHES, S. H, CRAGG, G. M, BOYD, M. R
Published in Journal of medicinal chemistry (24.07.1992)
Published in Journal of medicinal chemistry (24.07.1992)
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Journal Article
Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1
M J Currens, R J Gulakowski, J M Mariner, R A Moran, R W Buckheit, Jr, K R Gustafson, J B McMahon, M R Boyd
Published in The Journal of pharmacology and experimental therapeutics (01.11.1996)
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Published in The Journal of pharmacology and experimental therapeutics (01.11.1996)
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Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase
BOYER, P. L, CURRENS, M. J, MCMAHON, J. B, BOYD, M. R, HUGHES, S. H
Published in Journal of Virology (01.04.1993)
Published in Journal of Virology (01.04.1993)
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Journal Article
Comparative anti-HIV evaluation of diverse HIV-1-specific reverse transcriptase inhibitor-resistant virus isolates demonstrates the existence of distinct phenotypic subgroups
Buckheit, Robert W., Fliakas-Boltz, Valerie, Decker, William Don, Roberson, Joseph L., Stup, Tracy L., Pyle, Cathi A., White, E.Lucile, McMahon, James B., Currens, Michael J., Boyd, Michael R., Bader, John P.
Published in Antiviral research (01.03.1995)
Published in Antiviral research (01.03.1995)
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Journal Article
Biological and biochemical anti-human immunodeficiency virus activity of UC 38, a new non-nucleoside reverse transcriptase inhibitor
J B McMahon, R W Buckheit, Jr, R J Gulakowski, M J Currens, D T Vistica, R H Shoemaker, S F Stinson, J D Russell, J P Bader, V L Narayanan, R J Schultz, W G Brouwer, E E Felauer, M R Boyd
Published in The Journal of pharmacology and experimental therapeutics (01.01.1996)
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Published in The Journal of pharmacology and experimental therapeutics (01.01.1996)
Journal Article
Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the antiviral nucleoside 2′,3′-dideoxyguanosine
Ahluwalia, Gurpreet, Cooney, David A., Bondoc, Laureano L., Currens, Michael J., Ford, Harry, Johns, David G., Mitsuya, Hiroaki, Fridland, Arnold
Published in Biochemical and biophysical research communications (28.09.1990)
Published in Biochemical and biophysical research communications (28.09.1990)
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