Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer
Maximov, Philipp Y., Abderrahman, Balkees, Fanning, Sean W., Sengupta, Surojeet, Fan, Ping, Curpan, Ramona F., Rincon, Daniela Maria Quintana, Greenland, Jeffery A., Rajan, Shyamala S., Greene, Geoffrey L., Jordan, V. Craig
Published in Molecular pharmacology (01.08.2018)
Published in Molecular pharmacology (01.08.2018)
Get full text
Journal Article
A unifying biology of sex steroid-induced apoptosis in prostate and breast cancers
Maximov, Philipp Y, Abderrahman, Balkees, Curpan, Ramona F, Hawsawi, Yousef M, Fan, Ping, Jordan, V Craig
Published in Endocrine-related cancer (01.02.2018)
Published in Endocrine-related cancer (01.02.2018)
Get full text
Journal Article
Pharmacology and Molecular Mechanisms of Clinically Relevant Estrogen Estetrol and Estrogen Mimic BMI-135 for the Treatment of Endocrine-Resistant Breast Cancer
Abderrahman, Balkees, Maximov, Philipp Y, Curpan, Ramona F, Hanspal, Jay S, Fan, Ping, Xiong, Rui, Tonetti, Debra A, Thatcher, Gregory R J, Jordan, V Craig
Published in Molecular pharmacology (01.10.2020)
Published in Molecular pharmacology (01.10.2020)
Get full text
Journal Article
The molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy
Fan, Ping, Maximov, Philipp Y., Curpan, Ramona F., Abderrahman, Balkees, Jordan, V. Craig
Published in Molecular and cellular endocrinology (15.12.2015)
Published in Molecular and cellular endocrinology (15.12.2015)
Get full text
Journal Article
The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells
Maximov, Philipp Y, Abderrahman, Balkees, Hawsawi, Yousef M, Chen, Yue, Foulds, Charles E, Jain, Antrix, Malovannaya, Anna, Fan, Ping, Curpan, Ramona F, Han, Ross, Fanning, Sean W, Broom, Bradley M, Quintana Rincon, Daniela M, Greenland, Jeffery A, Greene, Geoffrey L, Jordan, V Craig
Published in Molecular pharmacology (01.07.2020)
Published in Molecular pharmacology (01.07.2020)
Get full text
Journal Article
Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer
Maximov, Philipp Y, Abderrahman, Balkees, Fanning, Sean W, Sengupta, Surojeet, Fan, Ping, Curpan, Ramona F, Rincon, Daniela Maria Quintana, Greenland, Jeffery A, Rajan, Shyamala S, Greene, Geoffrey L, Jordan, V Craig
Published in Molecular pharmacology (01.08.2018)
Published in Molecular pharmacology (01.08.2018)
Get full text
Journal Article
Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer
Abderrahman, Balkees, Maximov, Philipp Y, Curpan, Ramona F, Fanning, Sean W, Hanspal, Jay S, Fan, Ping, Foulds, Charles E, Chen, Yue, Malovannaya, Anna, Jain, Antrix, Xiong, Rui, Greene, Geoffrey L, Tonetti, Debra A, Thatcher, Gregory R J, Jordan, V Craig
Published in Molecular cancer therapeutics (01.01.2021)
Published in Molecular cancer therapeutics (01.01.2021)
Get full text
Journal Article
Pharmacological Relevance of Endoxifen in a Laboratory Simulation of Breast Cancer in Postmenopausal Patients
MAXIMOV, Philipp Y, MCDANIEL, Russell E, FERNANDES, Daphne J, BHATTA, Puspanjali, KOROSTYSHEVSKIY, Valeriy R, CURPAN, Ramona F, JORDAN, V. Craig
Published in JNCI : Journal of the National Cancer Institute (01.10.2014)
Published in JNCI : Journal of the National Cancer Institute (01.10.2014)
Get full text
Journal Article
A crowdsourcing evaluation of the NIH chemical probes
Oprea, Tudor I, Sklar, Larry A, Bologa, Cristian G, Boyer, Scott, Curpan, Ramona F, Glen, Robert C, Hopkins, Andrew L, Lipinski, Christopher A, Marshall, Garland R, Martin, Yvonne C, Ostopovici-Halip, Liliana, Rishton, Gilbert, Ursu, Oleg, Vaz, Roy J, Waller, Chris, Waldmann, Herbert
Published in Nature chemical biology (01.07.2009)
Published in Nature chemical biology (01.07.2009)
Get full text
Journal Article
Influence of the Length and Positioning of the Antiestrogenic Side Chain of Endoxifen and 4‑Hydroxytamoxifen on Gene Activation and Growth of Estrogen Receptor Positive Cancer Cells
Maximov, Philipp Y, Fernandes, Daphne J, McDaniel, Russell E, Myers, Cynthia B, Curpan, Ramona F, Jordan, V. Craig
Published in Journal of medicinal chemistry (12.06.2014)
Published in Journal of medicinal chemistry (12.06.2014)
Get full text
Journal Article
High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry
Curpan, Ramona F, Simons, Peter C, Zhai, Dayong, Young, Susan M, Carter, Mark B, Bologa, Cristian G, Oprea, Tudor I, Satterthwait, Arnold C, Reed, John C, Edwards, Bruce S, Sklar, Larry A
Published in Assay and drug development technologies (01.10.2011)
Published in Assay and drug development technologies (01.10.2011)
Get more information
Journal Article
Detection of Intracellular Granularity Induction in Prostate Cancer Cell Lines by Small Molecules Using the HyperCyt® High-Throughput Flow Cytometry System
Haynes, Mark K., Strouse, J. Jacob, Waller, Anna, Leitao, Andrei, Curpan, Ramona F., Bologa, Cristian, Oprea, Tudor I., Prossnitz, Eric R., Edwards, Bruce S., Sklar, Larry A., Thompson, Todd A.
Published in Journal of biomolecular screening (01.07.2009)
Published in Journal of biomolecular screening (01.07.2009)
Get full text
Journal Article
Modeling of dexmedetomidine conformers and their interactions with alpha2 adrenergic receptor subtypes
Curpăn, Ramona F., Halip, Liliana, Borota, Ana, Mracec, Maria, Mracec, Mircea
Published in Structural chemistry (01.06.2016)
Published in Structural chemistry (01.06.2016)
Get full text
Journal Article
The conformation of the estrogen receptor directs estrogen-induced apoptosis in breast cancer: a hypothesis
Maximov, Philipp, Sengupta, Surojeet, Lewis-Wambi, Joan S., Kim, Helen R., Curpan, Ramona F., Jordan, V. Craig
Published in Hormone molecular biology and clinical investigation (01.03.2011)
Published in Hormone molecular biology and clinical investigation (01.03.2011)
Get full text
Journal Article
Erratum: A crowdsourcing evaluation of the NIH chemical probes
Oprea, Tudor I, Bologa, Cristian G, Boyer, Scott, Curpan, Ramona F, Glen, Robert C, Hopkins, Andrew L, Lipinski, Christopher A, Marshall, Garland R, Martin, Yvonne C, Ostopovici-Halip, Liliana, Rishton, Gilbert, Ursu, Oleg, Vaz, Roy J, Waller, Chris, Waldmann, Herbert, Sklar, Larry A
Published in Nature chemical biology (01.08.2009)
Published in Nature chemical biology (01.08.2009)
Get full text
Journal Article