Phase 1 study of the selective BTK inhibitor zanubrutinib in B-cell malignancies and safety and efficacy evaluation in CLL
Tam, Constantine S., Trotman, Judith, Opat, Stephen, Burger, Jan A., Cull, Gavin, Gottlieb, David, Harrup, Rosemary, Johnston, Patrick B., Marlton, Paula, Munoz, Javier, Seymour, John F., Simpson, David, Tedeschi, Alessandra, Elstrom, Rebecca, Yu, Yiling, Tang, Zhiyu, Han, Lynn, Huang, Jane, Novotny, William, Wang, Lai, Roberts, Andrew W.
Published in Blood (12.09.2019)
Published in Blood (12.09.2019)
Get full text
Journal Article
A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study
Tam, Constantine S., Opat, Stephen, D'Sa, Shirley, Jurczak, Wojciech, Lee, Hui-Peng, Cull, Gavin, Owen, Roger G., Marlton, Paula, Wahlin, Björn E., Sanz, Ramón Garcia, McCarthy, Helen, Mulligan, Stephen, Tedeschi, Alessandra, Castillo, Jorge J., Czyz, Jaroslaw, Fernández de Larrea, Carlos, Belada, David, Libby, Edward, Matous, Jeffrey V., Motta, Marina, Siddiqi, Tanya, Tani, Monica, Trneny, Marek, Minnema, Monique C., Buske, Christian, Leblond, Veronique, Trotman, Judith, Chan, Wai Y., Schneider, Jingjing, Ro, Sunhee, Cohen, Aileen, Huang, Jane, Dimopoulos, Meletios
Published in Blood (29.10.2020)
Published in Blood (29.10.2020)
Get full text
Journal Article
Early treatment intensification with R-ICE and 90Y-ibritumomab tiuxetan (Zevalin)-BEAM stem cell transplantation in patients with high-risk diffuse large B-cell lymphoma patients and positive interim PET after 4 cycles of R-CHOP-14
Hertzberg, Mark, Gandhi, Maher K, Trotman, Judith, Butcher, Belinda, Taper, John, Johnston, Amanda, Gill, Devinder, Ho, Shir-Jing, Cull, Gavin, Fay, Keith, Chong, Geoff, Grigg, Andrew, Lewis, Ian D, Milliken, Sam, Renwick, William, Hahn, Uwe, Filshie, Robin, Kannourakis, George, Watson, Anne-Marie, Warburton, Pauline, Wirth, Andrew, Seymour, John F, Hofman, Michael S, Hicks, Rodney J
Published in Haematologica (Roma) (01.02.2017)
Published in Haematologica (Roma) (01.02.2017)
Get full text
Journal Article
Zanubrutinib, Alone and in Combination With Tislelizumab, for the Treatment of Richter Transformation of Chronic Lymphocytic Leukemia
Tam, Constantine, Munoz, Javier, Cull, Gavin, Opat, Stephen, Allewelt, Heather, Zhang, Xiaoping, Stern, Jennifer C., Hilger, James, By, Kunthel, Cohen, Aileen, Tedeschi, Alessandra
Published in HemaSphere (01.04.2023)
Published in HemaSphere (01.04.2023)
Get full text
Journal Article
How comparable are patient outcomes in the “real-world” with populations studied in pivotal AML trials?
Tiong, Ing Soo, Wall, Meaghan, Bajel, Ashish, Kalro, Akash, Fleming, Shaun, Roberts, Andrew W., Thiagarajah, Nisha, Chua, Chong Chyn, Latimer, Maya, Yeung, David, Marlton, Paula, Johnston, Amanda, Enjeti, Anoop, Fong, Chun Yew, Cull, Gavin, Larsen, Stephen, Kennedy, Glen, Schwarer, Anthony, Kipp, David, Ramanathan, Sundra, Verner, Emma, Tiley, Campbell, Morris, Edward, Hahn, Uwe, Moore, John, Taper, John, Purtill, Duncan, Warburton, Pauline, Stevenson, William, Murphy, Nicholas, Tan, Peter, Beligaswatte, Ashanka, Mutsando, Howard, Hertzberg, Mark, Shortt, Jake, Szabo, Ferenc, Dunne, Karin, Wei, Andrew H.
Published in Blood cancer journal (New York) (26.03.2024)
Published in Blood cancer journal (New York) (26.03.2024)
Get full text
Journal Article
PB1926: EFFICACY AND SAFETY OF ONCE DAILY (QD) VS TWICE DAILY (BID) ZANUBRUTINIB FOR PATIENTS WITH VARIOUS B-CELL MALIGNANCIES: A COMPARATIVE SUMMARY OF CLINICAL DATA AND EXPOSURE-RESPONSE ANALYSES
Tam, Constantine, Shadman, Mazyar, Sharman, Jeff, Cull, Gavin, Phillips, Tycel, Trotman, Judith, Cohen, Aileen, Allewelt, Heather, Crescenzo, Rocco, Delarue, Richard, Zhang, Heather, Tariq, Bilal, Sahasranaman, Sri, Ou, Ying C, Flinn, Ian W
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
Get full text
Journal Article
An international multicenter retrospective analysis of patients with extranodal marginal zone lymphoma and histologically confirmed central nervous system and dural involvement
Sunderland, Andrew J., Steiner, Raphael E., Al Zahrani, Musa, Pinnix, Chelsea C., Dabaja, Bouthaina Shbib, Gunther, Jillian R., Nastoupil, Loretta J., Jerkeman, Mats, Joske, David, Cull, Gavin, El‐Galaly, Tarec, Villa, Diego, Cheah, Chan Yoon
Published in Cancer medicine (Malden, MA) (01.01.2020)
Published in Cancer medicine (Malden, MA) (01.01.2020)
Get full text
Journal Article
Effective clearance of Ara-U the major metabolite of cytosine arabinoside (Ara-C) by hemodialysis in a patient with lymphoma and end-stage renal failure
Radeski, Dejan, Cull, Gavin M., Cain, Michael, Hackett, L. Peter, Ilett, Kenneth F.
Published in Cancer chemotherapy and pharmacology (01.04.2011)
Published in Cancer chemotherapy and pharmacology (01.04.2011)
Get full text
Journal Article
Incidence and nature of CD20‐negative relapses following rituximab therapy in aggressive B‐cell non‐Hodgkin's lymphoma: a retrospective review
Kennedy, Glen A., Tey, Siok‐Keen, Cobcroft, Ralph, Marlton, Paula, Cull, Gavin, Grimmett, Karen, Thomson, Damien, Gill, Devinder
Published in British journal of haematology (01.11.2002)
Published in British journal of haematology (01.11.2002)
Get full text
Journal Article
Zanubrutinib for the treatment of patients with Waldenström macroglobulinemia: 3 years of follow-up
Trotman, Judith, Opat, Stephen, Gottlieb, David, Simpson, David, Marlton, Paula, Cull, Gavin, Munoz, Javier, Tedeschi, Alessandra, Roberts, Andrew W., Seymour, John F., Atwal, Siminder Kaur, Yu, Yiling, Novotny, William, Holmgren, Eric, Tan, Ziwen, Hilger, James D., Huang, Jane, Tam, Constantine S.
Published in Blood (29.10.2020)
Published in Blood (29.10.2020)
Get full text
Journal Article
Rituximab in patients with primary CNS lymphoma (HOVON 105/ALLG NHL 24): a randomised, open-label, phase 3 intergroup study
Bromberg, Jacoline E C, Issa, Samar, Bakunina, Katerina, Minnema, Monique C, Seute, Tatjana, Durian, Marc, Cull, Gavin, Schouten, Harry C, Stevens, Wendy B C, Zijlstra, Josee M, Baars, Joke W, Nijland, Marcel, Mason, Kylie D, Beeker, Aart, van den Bent, Martin J, Beijert, Max, Gonzales, Michael, de Jong, Daphne, Doorduijn, Jeanette K
Published in The lancet oncology (01.02.2019)
Published in The lancet oncology (01.02.2019)
Get full text
Journal Article
Indolent relapse after initial aggressive B-cell lymphoma: a single institution experience in the rituximab era
Fasser, Daniel, Lewis, Katharine, Leslie, Connull, Cull, Gavin, Radeski, Dejan, Augustson, Bradley, Howman, Rebecca, Joske, David, Crawford, Julie, Grove, Carolyn, Cheah, Chan Y
Published in Leukemia & lymphoma (18.10.2024)
Published in Leukemia & lymphoma (18.10.2024)
Get more information
Journal Article
Zanubrutinib for treatment‐naïve and relapsed/refractory chronic lymphocytic leukaemia: long‐term follow‐up of the phase I/II AU‐003 study
Cull, Gavin, Burger, Jan A., Opat, Stephen, Gottlieb, David, Verner, Emma, Trotman, Judith, Marlton, Paula, Munoz, Javier, Johnston, Patrick, Simpson, David, Stern, Jennifer C., Prathikanti, Radha, Wu, Kenneth, Novotny, William, Huang, Jane, Tam, Constantine S.
Published in British journal of haematology (01.03.2022)
Published in British journal of haematology (01.03.2022)
Get full text
Journal Article
Clinical Outcomes in Patients with Waldenström Macroglobulinemia (WM) Receiving Ibrutinib on the Phase 3 ASPEN Study ≥1 Year After Transitioning to Zanubrutinib
Garcia-Sanz, Ramon, Owen, Roger, Jurczak, Wojciech, Dimopoulos, Meletios A., McCarthy, Helen, Cull, Gavin, Opat, Stephen, Castillo, Jorge J., Kersten, Marie José, Wahlin, Björn E., Grosicki, Sebastian, Prathikanti, Radha, Tian, Tian, Allewelt, Heather, Cohen, Aileen Cleary, Tam, Constantine S.
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
Get full text
Journal Article
Green Tea Polyphenol “Epigallocatechin-3-Gallate”, differentially induces apoptosis in CLL B-and T-Cells but not in healthy B-and T-Cells in a dose dependant manner
Cornwall, Scott, Cull, Gavin, Joske, David, Ghassemifar, Reza
Published in Leukemia research (01.12.2016)
Published in Leukemia research (01.12.2016)
Get full text
Journal Article
Zanubrutinib for the treatment of relapsed or refractory mantle cell lymphoma
Tam, Constantine S., Opat, Stephen, Simpson, David, Cull, Gavin, Munoz, Javier, Phillips, Tycel J., Kim, Won Seog, Rule, Simon, Atwal, Siminder Kaur, Wei, Rachel, Novotny, William, Huang, Jane, Wang, Michael, Trotman, Judith
Published in Blood advances (22.06.2021)
Published in Blood advances (22.06.2021)
Get full text
Journal Article
Lenalidomide Consolidation Improves Measurable Residual Disease (MRD) Rates and Progression Free Survival in Patients with Chronic Lymphocytic Leukemia Following Initial FCR Chemotherapy - Final Analysis of CLL6 Residuum Study of the Australian Leukaemia and Lymphoma Group (ALLG) and the French Innovative Leukemia Organization (FILO)
Aurran-Schleinitz, Therese, Mulligan, Stephen P, Letestu, Remi, Bene, Marie Christine, Cull, Gavin, Vilque, Jean Pierre, Tam, Constantine S., De Guibert, Sophie, Harrup, Rosemary Anne, Drenou, Bernard, Grigg, Andrew P, Voillat, Laurent, Butcher, Belinda E, Dartigeas, Caroline, Eek, Richard, Daguindau, Nicolas, Forsyth, Cecily, Tiab, Mourad, Smith, Delaine, Curnow, Jennifer, Leblond, Veronique, Larsen, Stephen Robert, Cymbalista, Florence, Gottlieb, David
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
Get full text
Journal Article
Zanubrutinib Versus Ibrutinib in Symptomatic Waldenström Macroglobulinemia: Final Analysis From the Randomized Phase III ASPEN Study
Dimopoulos, Meletios A, Opat, Stephen, D'Sa, Shirley, Jurczak, Wojciech, Lee, Hui-Peng, Cull, Gavin, Owen, Roger G, Marlton, Paula, Wahlin, Björn E, Garcia-Sanz, Ramon, McCarthy, Helen, Mulligan, Stephen, Tedeschi, Alessandra, Castillo, Jorge J, Czyz, Jaroslaw, Fernández de Larrea, Carlos, Belada, David, Libby, Edward, Matous, Jeffrey, Motta, Marina, Siddiqi, Tanya, Tani, Monica, Trněný, Marek, Minnema, Monique C, Buske, Christian, Leblond, Veronique, Treon, Steven P, Trotman, Judith, Chan, Wai Y, Schneider, Jingjing, Allewelt, Heather, Patel, Sheel, Cohen, Aileen, Tam, Constantine S
Published in Journal of clinical oncology (20.11.2023)
Published in Journal of clinical oncology (20.11.2023)
Get full text
Journal Article