Biological, chemical, and biochemical strategies for modifying glycopeptide antibiotics
Marschall, Edward, Cryle, Max J., Tailhades, Julien
Published in The Journal of biological chemistry (06.12.2019)
Published in The Journal of biological chemistry (06.12.2019)
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Journal Article
X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis
Haslinger, Kristina, Peschke, Madeleine, Brieke, Clara, Maximowitsch, Egle, Cryle, Max J.
Published in Nature (London) (07.05.2015)
Published in Nature (London) (07.05.2015)
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Journal Article
Unrivalled diversity: the many roles and reactions of bacterial cytochromes P450 in secondary metabolism
Greule, Anja, Stok, Jeanette E, De Voss, James J, Cryle, Max J
Published in Natural product reports (15.08.2018)
Published in Natural product reports (15.08.2018)
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Journal Article
Beyond vancomycin: recent advances in the modification, reengineering, production and discovery of improved glycopeptide antibiotics to tackle multidrug-resistant bacteria
Hansen, Mathias H, Stegmann, Evi, Cryle, Max J
Published in Current opinion in biotechnology (01.10.2022)
Published in Current opinion in biotechnology (01.10.2022)
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Journal Article
Structural diversity, biosynthesis, and biological functions of lipopeptides from Streptomyces
Zhang, Songya, Chen, Yunliang, Zhu, Jing, Lu, Qiujie, Cryle, Max J, Zhang, Youming, Yan, Fu
Published in Natural product reports (22.03.2023)
Published in Natural product reports (22.03.2023)
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Journal Article
Enzyme engineering lets us play with new building blocks in non-ribosomal peptide synthesis
Ratnayake, Minuri S., Hansen, Mathias H., Cryle, Max J.
Published in Structure (London) (02.05.2024)
Published in Structure (London) (02.05.2024)
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Journal Article
A route to diastereomerically pure phenylglycine thioester peptides: crucial intermediates for investigating glycopeptide antibiotic biosynthesis
Tailhades, Julien, Schoppet, Melanie, Greule, Anja, Peschke, Madeleine, Brieke, Clara, Cryle, Max J.
Published in Chemical communications (Cambridge, England) (2018)
Published in Chemical communications (Cambridge, England) (2018)
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Journal Article
Chemical probes reveal the timing of early chlorination in vancomycin biosynthesis
Leng, Daniel J, Greule, Anja, Cryle, Max J, Tosin, Manuela
Published in Chemical communications (Cambridge, England) (04.03.2021)
Published in Chemical communications (Cambridge, England) (04.03.2021)
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Journal Article
Cytochrome P450Blt Enables Versatile Peptide Cyclisation to Generate Histidine‐ and Tyrosine‐Containing Crosslinked Tripeptide Building Blocks
Zhao, Yongwei, Marschall, Edward, Treisman, Maxine, McKay, Alasdair, Padva, Leo, Crüsemann, Max, Nelson, David R., Steer, David L., Schittenhelm, Ralf B., Tailhades, Julien, Cryle, Max J.
Published in Angewandte Chemie International Edition (12.09.2022)
Published in Angewandte Chemie International Edition (12.09.2022)
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Journal Article
Understanding the crucial interactions between Cytochrome P450s and non-ribosomal peptide synthetases during glycopeptide antibiotic biosynthesis
Peschke, Madeleine, Gonsior, Melanie, Süssmuth, Roderich D, Cryle, Max J
Published in Current opinion in structural biology (01.12.2016)
Published in Current opinion in structural biology (01.12.2016)
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Journal Article
Sequential In Vitro Cyclization by Cytochrome P450 Enzymes of Glycopeptide Antibiotic Precursors Bearing the X-Domain from Nonribosomal Peptide Biosynthesis
Brieke, Clara, Peschke, Madeleine, Haslinger, Kristina, Cryle, Max J.
Published in Angewandte Chemie International Edition (21.12.2015)
Published in Angewandte Chemie International Edition (21.12.2015)
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Journal Article
Structural aspects of phenylglycines, their biosynthesis and occurrence in peptide natural products
Al Toma, Rashed S, Brieke, Clara, Cryle, Max J, Süssmuth, Roderich D
Published in Natural product reports (01.08.2015)
Published in Natural product reports (01.08.2015)
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Journal Article
Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity
Izoré, Thierry, Candace Ho, Y. T., Kaczmarski, Joe A., Gavriilidou, Athina, Chow, Ka Ho, Steer, David L., Goode, Robert J. A., Schittenhelm, Ralf B., Tailhades, Julien, Tosin, Manuela, Challis, Gregory L., Krenske, Elizabeth H., Ziemert, Nadine, Jackson, Colin J., Cryle, Max J.
Published in Nature communications (04.05.2021)
Published in Nature communications (04.05.2021)
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Journal Article