Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments
Crowl, John T., Heeg, Maximilian, Ferry, Amir, Milner, J. Justin, Omilusik, Kyla D., Toma, Clara, He, Zhaoren, Chang, John T., Goldrath, Ananda W.
Published in Nature immunology (01.07.2022)
Published in Nature immunology (01.07.2022)
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Journal Article
Intracellular Nucleic Acid Detection in Autoimmunity
Crowl, John T, Gray, Elizabeth E, Pestal, Kathleen, Volkman, Hannah E, Stetson, Daniel B
Published in Annual review of immunology (26.04.2017)
Published in Annual review of immunology (26.04.2017)
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Journal Article
SUMO2 and SUMO3 redundantly prevent a noncanonical type I interferon response
Crowl, John T., Stetson, Daniel B.
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2018)
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Journal Article
Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy
Milner, J. Justin, Toma, Clara, He, Zhaoren, Kurd, Nadia S., Nguyen, Quynh P., McDonald, Bryan, Quezada, Lauren, Widjaja, Christella E., Witherden, Deborah A., Crowl, John T., Shaw, Laura A., Yeo, Gene W., Chang, John T., Omilusik, Kyla D., Goldrath, Ananda W.
Published in Immunity (Cambridge, Mass.) (19.05.2020)
Published in Immunity (Cambridge, Mass.) (19.05.2020)
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Journal Article
Outsmart™ IL-2/15, a Novel Cytokine Designed to Enhance ROR1-Specific CAR T Anti-Tumor Activity While Minimizing Treg Activation and Systemic Cytokine Exposure
Moffett, Howell, Weitzner, Brian, Davenport, Thaddeus, Tait, Leah, Tan, Tina, Baker, Laura, Crowl, John, Obenza, Willimark, Hammerson, Bradley, Kirkpatrick, Robin, Sample, Paul, Jones, Lesley, Hermans, Erik, Langan, Robert, Haworth, Kevin, Boyken, Scott, Foster, Aaron, Lajoie, Marc
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Identification of Trex1 interacting proteins and endogenous DNA substrates
Crowl, John T, Brunette, Rebecca, Stetson, Daniel B
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
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Journal Article
Development of a Regulated, Optimized Mesothelin Chimeric Antigen Receptor (CAR) for the Treatment of Mesothelin Positive Cancers
Yokoyama, Jason, Wang, Allan, Steele, Maria, Crowl, John, Davenport, Thaddeus, Hammer, Jared, Obenza, Willimark, Montoya, Vanessa, Kirkpatrick, Robin, Baker, Laura, Tan, Tina, Bringgold, Emily, Shirley, Kristie, Deshmukh, Maanasee, Hammerson, Bradley, Sample, Paul, Weitzner, Brian, Yuan, Shujun, Foster, Aaron, Lajoie, Marc, Boyken, Scott, Moffett, Howell, Amin, Rupesh
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Abstract 51: OPB-101: An optimized mesothelin-specific CAR T cell product expressing CD8-targeted IL-2/15 and engineered to resist T cell exhaustion
Amin, Rupesh, Moffett, Howell, Haworth, Kevin, Chen, Jerry, Yokoyama, Jason, Wang, Allan, Tait, Leah, Steele, Maria, Crowl, John, Davenport, Thaddeus, DeSautelle, Joseph, Hammer, Jared, Obenza, Willimark, Montoya, Vanessa, Kirkpatrick, Robin, Baker, Laura, Tan, Tina, Shirley, Kristie, Hammerson, Bradley, Langan, Robert, Clausen, David, Sample, Paul, Weitzner, Brian, Yuan, Shujun, Lajoie, Marc, Boyken, Scott, Foster, Aaron
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Functional delineation of tissue-resident CD8 T cell heterogeneity during infection and cancer
Milner, J Justin, Toma, Clara, He, Zhaoren, Kurd, Nadia S, Nguyen, Quynh P, Mcdonald, Bryan, Quezada, Lauren, Widjaja, Christella E, Witherden, Deborah A, Crowl, John T, Yeo, Gene W, Chang, John T, Omilusik, Kyla D, Goldrath, Ananda W
Published in bioRxiv (06.03.2020)
Published in bioRxiv (06.03.2020)
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