Novel inhibitors of cholesterol degradation in Mycobacterium tuberculosis reveal how the bacterium's metabolism is constrained by the intracellular environment
VanderVen, Brian C, Fahey, Ruth J, Lee, Wonsik, Liu, Yancheng, Abramovitch, Robert B, Memmott, Christine, Crowe, Adam M, Eltis, Lindsay D, Perola, Emanuele, Deininger, David D, Wang, Tiansheng, Locher, Christopher P, Russell, David G
Published in PLoS pathogens (01.02.2015)
Published in PLoS pathogens (01.02.2015)
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Journal Article
Actinobacterial Acyl Coenzyme A Synthetases Involved in Steroid Side-Chain Catabolism
Casabon, Israël, Swain, Kendra, Crowe, Adam M, Eltis, Lindsay D, Mohn, William W
Published in Journal of Bacteriology (01.02.2014)
Published in Journal of Bacteriology (01.02.2014)
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Journal Article
FadD3 is an acyl‐CoA synthetase that initiates catabolism of cholesterol rings C and D in actinobacteria
Casabon, Israël, Crowe, Adam M., Liu, Jie, Eltis, Lindsay D.
Published in Molecular microbiology (01.01.2013)
Published in Molecular microbiology (01.01.2013)
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Journal Article
The unusual convergence of steroid catabolic pathways in Mycobacterium abscessus
Crowe, Adam M, Krekhno, Jessica M C, Brown, Kirstin L, Kulkarni, Jayesh A, Yam, Katherine C, Eltis, Lindsay D
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2022)
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Journal Article
IpdAB, a virulence factor in Mycobacterium tuberculosis, is a cholesterol ring-cleaving hydrolase
Crowe, Adam M., Workman, Sean D., Watanabe, Nobuhiko, Worrall, Liam J., Strynadka, Natalie C. J., Eltis, Lindsay D.
Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2018)
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Journal Article
Catabolism of the Last Two Steroid Rings in Mycobacterium tuberculosis and Other Bacteria
Crowe, Adam M, Casabon, Israël, Brown, Kirstin L, Liu, Jie, Lian, Jennifer, Rogalski, Jason C, Hurst, Timothy E, Snieckus, Victor, Foster, Leonard J, Eltis, Lindsay D
Published in mBio (04.04.2017)
Published in mBio (04.04.2017)
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IpdE1-IpdE2 Is a Heterotetrameric Acyl Coenzyme A Dehydrogenase That Is Widely Distributed in Steroid-Degrading Bacteria
Gadbery, John E, Round, James W, Yuan, Tianao, Wipperman, Matthew F, Story, Keith T, Crowe, Adam M, Casabon, Israel, Liu, Jie, Yang, Xinxin, Eltis, Lindsay D, Sampson, Nicole S
Published in Biochemistry (Easton) (17.03.2020)
Published in Biochemistry (Easton) (17.03.2020)
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Journal Article
Structural and Functional Characterization of a Ketosteroid Transcriptional Regulator of Mycobacterium tuberculosis
Crowe, Adam M., Stogios, Peter J., Casabon, Israël, Evdokimova, Elena, Savchenko, Alexei, Eltis, Lindsay D.
Published in The Journal of biological chemistry (09.01.2015)
Published in The Journal of biological chemistry (09.01.2015)
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The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis
Ho, Ngoc Anh Thu, Dawes, Stephanie S., Crowe, Adam M., Casabon, Israël, Gao, Chen, Kendall, Sharon L., Baker, Edward N., Eltis, Lindsay D., Lott, J.Shaun
Published in The Journal of biological chemistry (01.04.2016)
Published in The Journal of biological chemistry (01.04.2016)
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Journal Article
Functional analyses of three acyl-CoA synthetases involved in bile acid degradation in Pseudomonas putida DOC21
Barrientos, Álvaro, Merino, Estefanía, Casabon, Israël, Rodríguez, Joaquín, Crowe, Adam M., Holert, Johannes, Philipp, Bodo, Eltis, Lindsay D., Olivera, Elías R., Luengo, José M.
Published in Environmental microbiology (01.01.2015)
Published in Environmental microbiology (01.01.2015)
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Journal Article
FadD 3 is an acyl‐ CoA synthetase that initiates catabolism of cholesterol rings C and D in actinobacteria
Casabon, Israël, Crowe, Adam M., Liu, Jie, Eltis, Lindsay D.
Published in Molecular microbiology (01.01.2013)
Published in Molecular microbiology (01.01.2013)
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Journal Article
Functional analyses of three acyl-CoA synthetases involved in bile acid degradation in Pseudomonas putidaDOC21
Barrientos, Álvaro, Merino, Estefanía, Casabon, Israël, Rodriguez, Joaquín, Crowe, Adam M, Holert, Johannes, Philipp, Bodo, Eltis, Lindsay D, Olivera, Elías R, Luengo, José M
Published in Environmental microbiology (01.01.2015)
Published in Environmental microbiology (01.01.2015)
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Journal Article
Functional analyses of three acyl‐ CoA synthetases involved in bile acid degradation in P seudomonas putida DOC 21
Barrientos, Álvaro, Merino, Estefanía, Casabon, Israël, Rodríguez, Joaquín, Crowe, Adam M., Holert, Johannes, Philipp, Bodo, Eltis, Lindsay D., Olivera, Elías R., Luengo, José M.
Published in Environmental microbiology (01.01.2015)
Published in Environmental microbiology (01.01.2015)
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Novel Inhibitors of Cholesterol Degradation in Mycobacterium tuberculosis Reveal How the Bacterium's Metabolism Is Constrained by the Intracellular Environment: e1004679
VanderVen, Brian C, Fahey, Ruth J, Lee, Wonsik, Liu, Yancheng, Abramovitch, Robert B, Memmott, Christine, Crowe, Adam M, Eltis, Lindsay D, Perola, Emanuele, Deininger, David D, Wang, Tiansheng, Locher, Christopher P, Russell, David G
Published in PLoS pathogens (01.02.2015)
Published in PLoS pathogens (01.02.2015)
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Catabolism of the Last Two Steroid Rings in italic toggle="yes">Mycobacterium tuberculosis /italic> and Other Bacteria
Adam M. Crowe, Israël Casabon, Kirstin L. Brown, Jie Liu, Jennifer Lian, Jason C. Rogalski, Timothy E. Hurst, Victor Snieckus, Leonard J. Foster, Lindsay D. Eltis
Published in mBio (01.05.2017)
Published in mBio (01.05.2017)
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