Phosphorothioate modified oligonucleotide-protein interactions
Crooke, Stanley T, Vickers, Timothy A, Liang, Xue-Hai
Published in Nucleic acids research (04.06.2020)
Published in Nucleic acids research (04.06.2020)
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Antisense technology: an overview and prospectus
Crooke, Stanley T., Baker, Brenda F., Crooke, Rosanne M., Liang, Xue-hai
Published in Nature reviews. Drug discovery (01.06.2021)
Published in Nature reviews. Drug discovery (01.06.2021)
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Journal Article
Cellular uptake and trafficking of antisense oligonucleotides
Crooke, Stanley T, Wang, Shiyu, Vickers, Timothy A, Shen, Wen, Liang, Xue-hai
Published in Nature biotechnology (01.03.2017)
Published in Nature biotechnology (01.03.2017)
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Journal Article
Antisense technology: A review
Crooke, Stanley T., Liang, Xue-Hai, Baker, Brenda F., Crooke, Rosanne M.
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression
Yu, Dongbo, Pendergraff, Hannah, Liu, Jing, Kordasiewicz, Holly B., Cleveland, Don W., Swayze, Eric E., Lima, Walt F., Crooke, Stanley T., Prakash, Thazha P., Corey, David R.
Published in Cell (31.08.2012)
Published in Cell (31.08.2012)
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RNA-Targeted Therapeutics
Crooke, Stanley T., Witztum, Joseph L., Bennett, C. Frank, Baker, Brenda F.
Published in Cell metabolism (03.04.2018)
Published in Cell metabolism (03.04.2018)
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Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials
Viney, Nicholas J, BSc, van Capelleveen, Julian C, MD, Geary, Richard S, PhD, Xia, Shuting, MS, Tami, Joseph A, PharmD, Yu, Rosie Z, PhD, Marcovina, Santica M, Prof, Hughes, Steven G, MD, Graham, Mark J, MS, Crooke, Rosanne M, PhD, Crooke, Stanley T, MD, Witztum, Joseph L, Prof, Stroes, Erik S, Prof, Tsimikas, Sotirios, Prof
Published in The Lancet (British edition) (05.11.2016)
Published in The Lancet (British edition) (05.11.2016)
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Journal Article
Annexin A2 facilitates endocytic trafficking of antisense oligonucleotides
Wang, Shiyu, Sun, Hong, Tanowitz, Michael, Liang, Xue-Hai, Crooke, Stanley T
Published in Nucleic acids research (06.09.2016)
Published in Nucleic acids research (06.09.2016)
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Journal Article
The Interaction of Phosphorothioate-Containing RNA Targeted Drugs with Proteins Is a Critical Determinant of the Therapeutic Effects of These Agents
Crooke, Stanley T, Seth, Punit P, Vickers, Timothy A, Liang, Xue-hai
Published in Journal of the American Chemical Society (02.09.2020)
Published in Journal of the American Chemical Society (02.09.2020)
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Journal Article
Clinical and Preclinical Pharmacokinetics and Pharmacodynamics of Mipomersen (Kynamro®): A Second-Generation Antisense Oligonucleotide Inhibitor of Apolipoprotein B
Geary, Richard S., Baker, Brenda F., Crooke, Stanley T.
Published in Clinical pharmacokinetics (01.02.2015)
Published in Clinical pharmacokinetics (01.02.2015)
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