Arginine deprivation alters microglial polarity and synergizes with radiation to eradicate non-arginine-auxotrophic glioblastoma tumors
Hajji, Nabil, Garcia-Revilla, Juan, Soto, Manuel Sarmiento, Perryman, Richard, Symington, Jake, Quarles, Chad C, Healey, Deborah R, Guo, Yijie, Orta-Vázquez, Manuel Luis, Mateos-Cordero, Santiago, Shah, Khalid, Bomalaski, John, Anichini, Giulio, Tzakos, Andreas G, Crook, Timothy, O'Neill, Kevin, Scheck, Adrienne C, Venero, Jose Luis, Syed, Nelofer
Published in The Journal of clinical investigation (15.03.2022)
Published in The Journal of clinical investigation (15.03.2022)
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A Phase I Study of Pegylated Arginine Deiminase (Pegargiminase), Cisplatin, and Pemetrexed in Argininosuccinate Synthetase 1-Deficient Recurrent High-grade Glioma
Hall, Peter E, Lewis, Rachel, Syed, Nelofer, Shaffer, Richard, Evanson, Jane, Ellis, Stephen, Williams, Matthew, Feng, Xiaoxing, Johnston, Amanda, Thomson, Jim A, Harris, Fiona P, Jena, Raj, Matys, Tomasz, Jefferies, Sarah, Smith, Kate, Wu, Bor-Wen, Bomalaski, John S, Crook, Timothy, O'Neill, Kevin, Paraskevopoulos, Dimitris, Khadeir, Ramsay S, Sheaff, Michael, Pacey, Simon, Plowman, Piers N, Szlosarek, Peter W
Published in Clinical cancer research (01.05.2019)
Published in Clinical cancer research (01.05.2019)
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Dynamic changes in tumor profiling reveal intra- and inter-tumoral heterogeneity focused on an uncharacterized HER2 mutation: a case report of a young breast cancer patient
Schaffrin-Nabe, Dörthe, Josten-Nabe, Anke, Tannapfel, Andrea, Uhl, Waldemar, Garmer, Marietta, Kurzrock, Razelle, Crook, Timothy, Limaye, Sewanti, Schuster, Stefan, Patil, Darshana, Schaffrin, Merle, Mokbel, Kefah, Voigtmann, Rudolf
Published in Frontiers in oncology (03.05.2024)
Published in Frontiers in oncology (03.05.2024)
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Design Principles Governing the Development of Theranostic Anticancer Agents and Their Nanoformulations with Photoacoustic Properties
Kyrkou, Stavroula G, Vrettos, Eirinaios I, Gorpas, Dimitris, Crook, Timothy, Syed, Nelofer, Tzakos, Andreas G
Published in Pharmaceutics (04.02.2022)
Published in Pharmaceutics (04.02.2022)
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Improved Treatment Outcomes by Using Patient Specific Drug Combinations in Mammalian Target of Rapamycin Activated Advanced Metastatic Cancers
Crook, Timothy, Patil, Darshana, Gaya, Andrew, Plowman, Nicholas, Limaye, Sewanti, Ranade, Anantbhushan, Bhatt, Amit, Page, Raymond, Akolkar, Dadasaheb
Published in Frontiers in pharmacology (16.04.2021)
Published in Frontiers in pharmacology (16.04.2021)
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Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): distant metastasis-free survival results from a double-blind, randomised, controlled, phase 3 trial
Blank, Christian U, Mandalà, Mario, Long, Georgina V, Atkinson, Victoria G, Dalle, Stéphane, Haydon, Andrew M, Meshcheryakov, Andrey, Carlino, Matteo S, Sandhu, Shahneen, Larkin, James, Puig, Susana, Ascierto, Paolo A, Koornstra, Rutger, Hernandez-Aya, Leonel, Di Giacomo, Anna Maria, Grob, Jean-Jacques, Gutzmer, Ralf, Jamal, Rahima, Lorigan, Paul C, van Akkooi, Alexander C J, Krepler, Clemens, Ibrahim, Nageatte, Marreaud, Sandrine, Kicinski, Michal, Suciu, Stefan, Robert, Caroline, Menzies, Alex, Lesimple, Thierry, Maio, Michele, Brown, Michael, Hersey, Peter, Schachter, Jacob, Barrow, Catherine, Song, Xinni, Dutriaux, Caroline, Quaglino, Pietro, Meier, Friedegund, Stroyakovskiy, Daniil, Bastholt, Lars, Guillot, Bernard, Garbe, Claus, Ortiz Romero, Pablo Luis, Grange, Florent, Mohr, Peter, Algazi, Alain, Bechter, Oliver, Hernberg, Micaela, Arnault, Jean-Philippe, Loquai, Carmen, Meiss, Frank, Simon, Jan-Christoph, Bar-Sela, Gil, Chiarion Sileni, Vanna, Fitzharris, Bernard, McCrystal, Mike, Parente, Phillip, Baurain, Jean-Francois, Hauschild, Axel, Yamazaki, Naoya, Dummer, Reinhard, Walker, John, Geoffrois, Lionel, Leccia, Marie-Thérèse, Kretschmer, Lutz, Hendler, Daniel, Lotem, Michal, Mackiewicz, Andrzej, Sekulovic, Lidija, Dunwoodie, Elaine, Hoeller, Christoph, Machet, Laurent, Corrie, Philippa, Schmidt, Henrik, Descamps, Vincent, Kiecker, Felix, Ferrucci, Pier Francesco, Aarts, Maureen, Jameson, Michael, Ferreira, Paula, Kim, Kevin, Hofmann-Wellenhof, Reiner, Aubin, François, Utikal, Jochen, Ferraresi, Virginia, Inozume, Takashi, Kiyohara, Yoshio, Groenewegen, Gerard, Kapiteijn, Helena, Casasola, Richard, Crook, Timothy, Marshall, Ernest, Skytta, Tanja, Avril, Marie-Francoise, Jouary, Thomas, Hein, Rüdiger, Terheyden, Patrick, Straume, Oddbjorn, Martins, César, Mukhametshina, Guzel, Nathan, Paul
Published in The lancet oncology (01.05.2021)
Published in The lancet oncology (01.05.2021)
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Profiling of circulating glial cells for accurate blood‐based diagnosis of glial malignancies
O'Neill, Kevin, Syed, Nelofer, Crook, Timothy, Dubey, Sudhir, Potharaju, Mahadev, Limaye, Sewanti, Ranade, Anantbhushan, Anichini, Giulio, Patil, Darshana, Datta, Vineet, Datar, Rajan
Published in International journal of cancer (01.04.2024)
Published in International journal of cancer (01.04.2024)
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PATH-24. ACCURATE IDENTIFICATION OF GLIAL MALIGNANCIES FROM PERIPHERAL BLOOD
Anichini, Giulio, Fulmali, Pooja, O'Neill, Kevin, Datta, Vineet, Crook, Timothy, Syed, Nelofer
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
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Development of programmable gemcitabine-GnRH pro-drugs bearing linker controllable “click” oxime bond tethers and preclinical evaluation against prostate cancer
Vrettos, Eirinaios I., Karampelas, Theodoros, Sayyad, Nisar, Kougioumtzi, Anastasia, Syed, Nelofer, Crook, Timothy, Murphy, Carol, Tamvakopoulos, Constantin, Tzakos, Andreas G.
Published in European journal of medicinal chemistry (05.02.2021)
Published in European journal of medicinal chemistry (05.02.2021)
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Abstract P5-11-17: Phase IIIb CompLEEment-1 study of ribociclib plus letrozole in the treatment of HR+/HER2- advanced breast cancer (ABC): Interim results from the UK cohort
Ring, Alistair, Crook, Timothy, Tuthill, Mark, Roylance, Rebecca, McGoldrick, Trevor, Chan, Stephen, Lo'Monte, Helen, Roberts, William
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Encapsulation of Temozolomide in a Calixarene Nanocapsule Improves Its Stability and Enhances Its Therapeutic Efficacy against Glioblastoma
Renziehausen, Alexander, Tsiailanis, Antonis D, Perryman, Richard, Stylos, Evgenios K, Chatzigiannis, Christos, O'Neill, Kevin, Crook, Timothy, Tzakos, Andreas G, Syed, Nelofer
Published in Molecular cancer therapeutics (01.09.2019)
Published in Molecular cancer therapeutics (01.09.2019)
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Hallmark Circulating Tumor-Associated Cell Clusters Signify 230 Times Higher One-Year Cancer Risk
Ranade, Anantbhushan, Bhatt, Amit, Page, Raymond, Limaye, Sewanti, Crook, Timothy, Akolkar, Dadasaheb, Patil, Darshana
Published in Cancer prevention research (Philadelphia, Pa.) (01.01.2021)
Published in Cancer prevention research (Philadelphia, Pa.) (01.01.2021)
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Circulating ensembles of tumor‐associated cells: A redoubtable new systemic hallmark of cancer
Akolkar, Dadasaheb, Patil, Darshana, Crook, Timothy, Limaye, Sewanti, Page, Raymond, Datta, Vineet, Patil, Revati, Sims, Cynthe, Ranade, Anantbhushan, Fulmali, Pradeep, Fulmali, Pooja, Srivastava, Navin, Devhare, Pradip, Apurwa, Sachin, Patel, Shoeb, Patil, Sanket, Adhav, Archana, Pawar, Sushant, Ainwale, Akshay, Chougule, Rohit, Apastamb, Madhavi, Srinivasan, Ajay, Datar, Rajan
Published in International journal of cancer (15.06.2020)
Published in International journal of cancer (15.06.2020)
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Adjuvant pembrolizumab versus placebo in resected stage III melanoma (EORTC 1325-MG/KEYNOTE-054): health-related quality-of-life results from a double-blind, randomised, controlled, phase 3 trial
Bottomley, Andrew, Blank, Christian U, Mandalà, Mario, Long, Georgina V, Atkinson, Victoria G, Khattak, Adnan, Carlino, Matteo S, Sandhu, Shahneen, Puig, Susana, Larkin, James, Lorigan, Paul C, Rutkowski, Piotr, Schadendorf, Dirk, Koornstra, Rutger, Hernandez-Aya, Leonel, Di Giacomo, Anna Maria, van den Eertwegh, Alfonsus J M, Grob, Jean-Jacques, Gutzmer, Ralf, Jamal, Rahima, Krepler, Clemens, Marreaud, Sandrine, Kicinski, Michal, Robert, Caroline, Lesimple, Thierry, Maio, Michele, Linette, Gerald, Mortier, Laurent, Svane, Inge Marie, Schachter, Jacob, Brown, Michael, Hersey, Peter, Barrow, Catherine, Kudchadkar, Ragini, Song, Xinni, Quaglino, Pietro, Queirolo, Paola, Stroyakovskiy, Daniil, Romero, Pablo Luis Ortiz, Bastholt, Lars, Garbe, Claus, Grange, Florent, Mohr, Peter, Bechter, Oliver, Loquai, Carmen, Meiss, Frank, Bar-Sela, Gil, Fitzharris, Bernard, Saiag, Philippe, Arnault, Jean-Philippe, Baurain, Jean-Francois, Combemale, Patrick, Dummer, Reinhard, Hauschild, Axel, Yamazaki, Naoya, Milhem, Mohammed, Kretschmer, Lutz, Dunwoodie, Elaine, Walker, John, Hendler, Daniel, Dzienis, Marcin, Hospers, Geke A.P., Hassel, Jessica, Passos, Maria-Jose, Levin, Max, Hoeller, Christoph, Machet, Laurent, Hallmeyer, Sigrun, Waterston, Ashita, Descamps, Vincent, Kiecker, Felix, Aarts, Maureen, Schmidt, Henrik, Raimundo, Ana, Lacour, Jean-Philippe, Berking, Carola, Ferrucci, Pier Francesco, Jameson, Michael, Kim, Kevin, Yokota, Kenji, Aubin, François, Kapiteijn, Helena, Boehncke, Wolf-Henning, Utikal, Jochen, Casasola, Richard, Marshall, Ernest, Richtig, Erika, Matkovic, Suzana, Crook, Timothy, Kiyohara, Yoshio, Avril, Marie-Francoise, Hein, Rüdiger, Nathan, Paul, Aoi, Jun, Skytta, Tanja, Jouary, Thomas, Takenouchi, Tatsuya, Straume, Oddbjorn, Martins, César, Mukhametshina, Guzel
Published in The lancet oncology (01.05.2021)
Published in The lancet oncology (01.05.2021)
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Abstract P3-10-15: Therapeutic targeting of HOX gene dysregulation in triple negative breast cancer
Arunachalam, Einthavy, Simpson, Guy R, Möller-Levet, Carla Sofia, Annels, Nicola, Morgan, Richard, Crook, Timothy Robert, Pandha, Hardev Singh
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Abstract P4-01-05: Circulating ensembles of tumor associated cells for detection of breast cancer
Crook, Timothy, Akolkar, Dadasaheb, Fulmali, Pradip, Patil, Revati, Sims, Cynthe, Fulmali, Pooja, Datta, Vineet, Apurwa, Sachin, Srinivasan, Ajay, Datar, Rajan
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Accurate Screening for Early-Stage Breast Cancer by Detection and Profiling of Circulating Tumor Cells
Crook, Timothy, Leonard, Robert, Mokbel, Kefah, Thompson, Alastair, Michell, Michael, Page, Raymond, Vaid, Ashok, Mehrotra, Ravi, Ranade, Anantbhushan, Limaye, Sewanti, Patil, Darshana, Akolkar, Dadasaheb, Datta, Vineet, Fulmali, Pradip, Apurwa, Sachin, Schuster, Stefan, Srinivasan, Ajay, Datar, Rajan
Published in Cancers (09.07.2022)
Published in Cancers (09.07.2022)
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Clinical utility of circulating tumor-associated cells to predict and monitor chemo-response in solid tumors
Crook, Timothy, Gaya, Andrew, Page, Raymond, Limaye, Sewanti, Ranade, Anantbhushan, Bhatt, Amit, Patil, Sanket, Kumar, Prashant, Patil, Darshana, Akolkar, Dadasaheb
Published in Cancer chemotherapy and pharmacology (01.02.2021)
Published in Cancer chemotherapy and pharmacology (01.02.2021)
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