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Tap, William D, Dr, Jones, Robin L, MD, Van Tine, Brian A, MD, Chmielowski, Bartosz, MD, Elias, Anthony D, Prof, Adkins, Douglas, Prof, Agulnik, Mark, MD, Cooney, Matthew M, MD, Livingston, Michael B, MD, Pennock, Gregory, MD, Hameed, Meera R, MD, Shah, Gaurav D, MD, Qin, Amy, PhD, Shahir, Ashwin, MD, Cronier, Damien M, PhD, Ilaria, Robert, MD, Conti, Ilaria, MD, Cosaert, Jan, MD, Schwartz, Gary K, Prof
Published in The Lancet (British edition) (30.07.2016)
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A Population Pharmacokinetic and Pharmacodynamic Analysis of Abemaciclib in a Phase I Clinical Trial in Cancer Patients
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A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models
Yin, Tinggui, Lallena, Maria J, Kreklau, Emiko L, Fales, Kevin R, Carballares, Santiago, Torrres, Raquel, Wishart, Graham N, Ajamie, Rose T, Cronier, Damien M, Iversen, Phillip W, Meier, Timothy I, Foreman, Robert T, Zeckner, Douglas, Sissons, Sean E, Halstead, Bart W, Lin, Aimee B, Donoho, Gregory P, Qian, Yuewei, Li, Shuyu, Wu, Song, Aggarwal, Amit, Ye, Xiang S, Starling, James J, Gaynor, Richard B, de Dios, Alfonso, Du, Jian
Published in Molecular cancer therapeutics (01.06.2014)
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Pharmacokinetics of doxorubicin following concomitant intravenous administration of olaratumab (IMC‐3G3) to patients with advanced soft tissue sarcoma
Villalobos, Victor M., Mo, Gary, Agulnik, Mark, Pollack, Seth M., Rushing, Daniel A., Singh, Arun, Van Tine, Brian A., McNaughton, Rhian, Decker, Rodney L., Zhang, Wei, Shahir, Ashwin, Cronier, Damien M.
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Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Other Solid Tumors
Patnaik, Amita, Rosen, Lee S, Tolaney, Sara M, Tolcher, Anthony W, Goldman, Jonathan W, Gandhi, Leena, Papadopoulos, Kyriakos P, Beeram, Muralidhar, Rasco, Drew W, Hilton, John F, Nasir, Aejaz, Beckmann, Richard P, Schade, Andrew E, Fulford, Angie D, Nguyen, Tuan S, Martinez, Ricardo, Kulanthaivel, Palaniappan, Li, Lily Q, Frenzel, Martin, Cronier, Damien M, Chan, Edward M, Flaherty, Keith T, Wen, Patrick Y, Shapiro, Geoffrey I
Published in Cancer discovery (01.07.2016)
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Population Pharmacokinetic Modeling of Olaratumab, an Anti-PDGFRα Human Monoclonal Antibody, in Patients with Advanced and/or Metastatic Cancer
Mo, Gary, Baldwin, John R., Luffer-Atlas, Debra, Ilaria, Robert L., Conti, Ilaria, Heathman, Michael, Cronier, Damien M.
Published in Clinical pharmacokinetics (01.03.2018)
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Phase 2 study of tabalumab, a human anti‐B‐cell activating factor antibody, with bortezomib and dexamethasone in patients with previously treated multiple myeloma
Raje, Noopur S., Moreau, Philippe, Terpos, Evangelos, Benboubker, Lotfi, Grząśko, Norbert, Holstein, Sarah A., Oriol, Albert, Huang, Shang‐Yi, Beksac, Meral, Kuliczkowski, Kazimierz, Tai, Datchen F., Wooldridge, James E., Conti, Ilaria, Kaiser, Christopher J., Nguyen, Tuan S., Cronier, Damien M., Palumbo, Antonio
Published in British journal of haematology (01.03.2017)
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Optimising the combination dosing strategy of abemaciclib and vemurafenib in BRAF-mutated melanoma xenograft tumours
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Exposure–response relationship of olaratumab for survival outcomes and safety when combined with doxorubicin in patients with soft tissue sarcoma
Jones, Robin L., Mo, Gary, Baldwin, John R., Peterson, Patrick M., Ilaria, Robert L., Conti, Ilaria, Cronier, Damien M., Tap, William D.
Published in Cancer chemotherapy and pharmacology (01.01.2019)
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Results of a Phase 1 Study of AME-133v (LY2469298), an Fc-Engineered Humanized Monoclonal Anti-CD20 Antibody, in FcγRIIIa-Genotyped Patients with Previously Treated Follicular Lymphoma
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Published in Clinical cancer research (01.03.2012)
Published in Clinical cancer research (01.03.2012)
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Phase II study of olaratumab with paclitaxel/carboplatin (P/C) or P/C alone in previously untreated advanced NSCLC
Gerber, David E., Swanson, Paul, Lopez-Chavez, Ariel, Wong, Lucas, Dowlati, Afshin, Pennell, Nathan A., Cronier, Damien M., Qin, Amy, Ilaria, Robert, Cosaert, Jan, Shahir, Ashwin, Baggstrom, Maria Q.
Published in Lung cancer (Amsterdam, Netherlands) (01.09.2017)
Published in Lung cancer (Amsterdam, Netherlands) (01.09.2017)
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Phase 1/2 Study of Ocaratuzumab, an Fc-Engineered Humanized Anti-CD20 Monoclonal Antibody, in Low-Affinity FcγRIIIa Patients with Previously Treated Follicular Lymphoma
Ganjoo, Kristen N., de Vos, Sven, Pohlman, Brad L., Flinn, Ian W., Forero-Torres, Andres, Enas, Nathan H., Cronier, Damien M., Dang, Nam H., Foon, Kenneth A., Carpenter, Susan P., Slapak, Christopher A., Link, Brian K., Smith, Mitchell R., Mapara, Markus Y., Wooldridge, James E.
Published in Leukemia & lymphoma (01.01.2015)
Published in Leukemia & lymphoma (01.01.2015)
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Abstract CT145: A phase I open-label study to evaluate the effect of olaratumab on the pharmacokinetics (PK) of doxorubicin (Dox) in patients with advanced soft tissue sarcoma (STS)
Villalobos, Victor, Agulnik, Mark, Pollack, Seth M., Rushing, Daniel A., Singh, Arun, Van Tine, Brian A., Okereke, Chukwuemeka, Ng, Wee Teck, Cronier, Damien M.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Olaratumab and doxorubicin versus doxorubicin alone in soft tissue sarcoma
Tap, William D., Jones, Robin L., Van Tine, Brian A., Chmielowski, Bartosz, Elias, Anthony D., Adkins, Douglas, Agulnik, Mark, Cooney, Matthew M., Livingston, Michael B., Pennock, Gregory, Hameed, Meera R., Shah, Gaurav D., Qin, Amy, Shahir, Ashwin, Cronier, Damien M., Ilaria, Robert, Conti, Ilaria, Cosaert, Jan, Schwartz, Gary K.
Published in The Lancet (British edition) (09.06.2016)
Published in The Lancet (British edition) (09.06.2016)
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Abstract P5-19-13: Clinical activity of abemaciclib, an oral cell cycle inhibitor, in metastatic breast cancer
Tolaney, Sara M, Rosen, Lee S, Beeram, Muralidhar, Goldman, Jonathan W, Gandhi, Leena, Tolcher, Anthony W, Papadopoulos, Kyriakos P, Rasco, Drew W, Myrand, Scott P, Kulanthaivel, Palaniappan, Andrews, Joan M, Frenzel, Martin, Cronier, Damien M, Chan, Edward M, Flaherty, Keith T, Wen, Patrick Y, Shapiro, Geoffrey I, Patnaik, Amita
Published in Cancer research (Chicago, Ill.) (01.05.2015)
Published in Cancer research (Chicago, Ill.) (01.05.2015)
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Abstract CT232: Clinical activity of LY2835219, a novel cell cycle inhibitor selective for CDK4 and CDK6, in patients with metastatic breast cancer
Patnaik, Amita, Rosen, Lee S., Tolaney, Sara M., Tolcher, Anthony W., Goldman, Jonathan W., Gandhi, Leena, Papadopoulos, Kyriakos P., Beeram, Muralidhar, Rasco, Drew W., Myrand, Scott P., Kulanthaivel, Palaniappan, Li, Lily, Frenzel, Martin, Cronier, Damien M., Chan, Edward M., Flaherty, Keith T., Wen, Patrick Y., Shapiro, Geoffrey I.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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