Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature
Seaman, Steven, Zhu, Zhongyu, Saha, Saurabh, Zhang, Xiaoyan M., Yang, Mi Young, Hilton, Mary Beth, Morris, Karen, Szot, Christopher, Morris, Holly, Swing, Deborah A., Tessarollo, Lino, Smith, Sean W., Degrado, Sylvia, Borkin, Dmitry, Jain, Nareshkumar, Scheiermann, Julia, Feng, Yang, Wang, Yanping, Li, Jinyu, Welsch, Dean, DeCrescenzo, Gary, Chaudhary, Amit, Zudaire, Enrique, Klarmann, Kimberly D., Keller, Jonathan R., Dimitrov, Dimiter S., St. Croix, Brad
Published in Cancer cell (10.04.2017)
Published in Cancer cell (10.04.2017)
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TEM8/ANTXR1-Specific CAR T Cells as a Targeted Therapy for Triple-Negative Breast Cancer
Byrd, Tiara T, Fousek, Kristen, Pignata, Antonella, Szot, Christopher, Samaha, Heba, Seaman, Steven, Dobrolecki, Lacey, Salsman, Vita S, Oo, Htoo Zarni, Bielamowicz, Kevin, Landi, Daniel, Rainusso, Nino, Hicks, John, Powell, Suzanne, Baker, Matthew L, Wels, Winfried S, Koch, Joachim, Sorensen, Poul H, Deneen, Benjamin, Ellis, Matthew J, Lewis, Michael T, Hegde, Meenakshi, Fletcher, Bradley S, St Croix, Brad, Ahmed, Nabil
Published in Cancer research (Chicago, Ill.) (15.01.2018)
Published in Cancer research (Chicago, Ill.) (15.01.2018)
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Novel metabolic role for BDNF in pancreatic β-cell insulin secretion
Fulgenzi, Gianluca, Hong, Zhenyi, Tomassoni-Ardori, Francesco, Barella, Luiz F., Becker, Jodi, Barrick, Colleen, Swing, Deborah, Yanpallewar, Sudhirkumar, Croix, Brad St, Wess, Jürgen, Gavrilova, Oksana, Tessarollo, Lino
Published in Nature communications (23.04.2020)
Published in Nature communications (23.04.2020)
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TEM8/ANTXR1 Blockade Inhibits Pathological Angiogenesis and Potentiates Tumoricidal Responses against Multiple Cancer Types
Chaudhary, Amit, Hilton, Mary Beth, Seaman, Steven, Haines, Diana C., Stevenson, Susan, Lemotte, Peter K., Tschantz, William R., Zhang, Xiaoyan M., Saha, Saurabh, Fleming, Tony, St. Croix, Brad
Published in Cancer cell (14.02.2012)
Published in Cancer cell (14.02.2012)
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CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors
Majzner, Robbie G, Theruvath, Johanna L, Nellan, Anandani, Heitzeneder, Sabine, Cui, Yongzhi, Mount, Christopher W, Rietberg, Skyler P, Linde, Miles H, Xu, Peng, Rota, Christopher, Sotillo, Elena, Labanieh, Louai, Lee, Daniel W, Orentas, Rimas J, Dimitrov, Dimiter S, Zhu, Zhongyu, Croix, Brad St, Delaidelli, Alberto, Sekunova, Alla, Bonvini, Ezio, Mitra, Siddhartha S, Quezado, Martha M, Majeti, Ravindra, Monje, Michelle, Sorensen, Poul H B, Maris, John M, Mackall, Crystal L
Published in Clinical cancer research (15.04.2019)
Published in Clinical cancer research (15.04.2019)
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COX-2 inhibition potentiates antiangiogenic cancer therapy and prevents metastasis in preclinical models
Xu, Lihong, Stevens, Janine, Hilton, Mary Beth, Seaman, Steven, Conrads, Thomas P, Veenstra, Timothy D, Logsdon, Daniel, Morris, Holly, Swing, Deborah A, Patel, Nimit L, Kalen, Joseph, Haines, Diana C, Zudaire, Enrique, St Croix, Brad
Published in Science translational medicine (25.06.2014)
Published in Science translational medicine (25.06.2014)
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Immune checkpoint B7-H3 is a therapeutic vulnerability in prostate cancer harboring PTEN and TP53 deficiencies
Shi, Wei, Wang, Yin, Zhao, Yuehui, Kim, Justin Jimin, Li, Haoyan, Meng, Chenling, Chen, Feiyu, Zhang, Jie, Mak, Duncan H, Van, Vivien, Leo, Javier, St Croix, Brad, Aparicio, Ana, Zhao, Di
Published in Science translational medicine (10.05.2023)
Published in Science translational medicine (10.05.2023)
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Journal Article
Genes that Distinguish Physiological and Pathological Angiogenesis
Seaman, Steven, Stevens, Janine, Yang, Mi Young, Logsdon, Daniel, Graff-Cherry, Cari, St. Croix, Brad
Published in Cancer cell (01.06.2007)
Published in Cancer cell (01.06.2007)
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Wnt7a induces a unique phenotype of monocyte‐derived macrophages with lower phagocytic capacity and differential expression of pro‐ and anti‐inflammatory cytokines
Wallace, Jennillee, Lutgen, Victoria, Avasarala, Sreedevi, Croix, Brad, Winn, Robert A., Al‐Harthi, Lena
Published in Immunology (01.02.2018)
Published in Immunology (01.02.2018)
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Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release
Szot, Christopher, Saha, Saurabh, Zhang, Xiaoyan M, Zhu, Zhongyu, Hilton, Mary Beth, Morris, Karen, Seaman, Steven, Dunleavey, James M, Hsu, Kuo-Sheng, Yu, Guo-Jun, Morris, Holly, Swing, Deborah A, Haines, Diana C, Wang, Yanping, Hwang, Jennifer, Feng, Yang, Welsch, Dean, DeCrescenzo, Gary, Chaudhary, Amit, Zudaire, Enrique, Dimitrov, Dimiter S, St Croix, Brad
Published in The Journal of clinical investigation (01.07.2018)
Published in The Journal of clinical investigation (01.07.2018)
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The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models
Kendsersky, Nathan M, Lindsay, Jarrett, Kolb, E Anders, Smith, Malcolm A, Teicher, Beverly A, Erickson, Stephen W, Earley, Eric J, Mosse, Yael P, Martinez, Daniel, Pogoriler, Jennifer, Krytska, Kateryna, Patel, Khushbu, Groff, David, Tsang, Matthew, Ghilu, Samson, Wang, Yifei, Seaman, Steven, Feng, Yang, Croix, Brad St, Gorlick, Richard, Kurmasheva, Raushan, Houghton, Peter J, Maris, John M
Published in Clinical cancer research (15.05.2021)
Published in Clinical cancer research (15.05.2021)
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Targeted Fluorogenic Cyanine Carbamates Enable In Vivo Analysis of Antibody-Drug Conjugate Linker Chemistry
Usama, Syed Muhammad, Marker, Sierra C., Caldwell, Donald R., Patel, Nimit L., Feng, Yang, Kalen, Joseph D., St Croix, Brad, Schnermann, Martin J.
Published in Journal of the American Chemical Society (29.12.2021)
Published in Journal of the American Chemical Society (29.12.2021)
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GPR124 Functions as a WNT7-Specific Coactivator of Canonical β-Catenin Signaling
Posokhova, Ekaterina, Shukla, Animesh, Seaman, Steven, Volate, Suresh, Hilton, Mary Beth, Wu, Bofan, Morris, Holly, Swing, Deborah A., Zhou, Ming, Zudaire, Enrique, Rubin, Jeffrey S., St. Croix, Brad
Published in Cell reports (Cambridge) (13.01.2015)
Published in Cell reports (Cambridge) (13.01.2015)
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Cancer cell survival depends on collagen uptake into tumor-associated stroma
Hsu, Kuo-Sheng, Dunleavey, James M., Szot, Christopher, Yang, Liping, Hilton, Mary Beth, Morris, Karen, Seaman, Steven, Feng, Yang, Lutz, Emily M., Koogle, Robert, Tomassoni-Ardori, Francesco, Saha, Saurabh, Zhang, Xiaoyan M., Zudaire, Enrique, Bajgain, Pradip, Rose, Joshua, Zhu, Zhongyu, Dimitrov, Dimiter S., Cuttitta, Frank, Emenaker, Nancy J., Tessarollo, Lino, St. Croix, Brad
Published in Nature communications (18.11.2022)
Published in Nature communications (18.11.2022)
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Orphan G-Protein Coupled Receptor GPRC5B Is Critical for Lymphatic Development
Xu, Wenjing, Nelson-Maney, Nathan P, Bálint, László, Kwon, Hyouk-Bum, Davis, Reema B, Dy, Danielle C M, Dunleavey, James M, St Croix, Brad, Caron, Kathleen M
Published in International journal of molecular sciences (20.05.2022)
Published in International journal of molecular sciences (20.05.2022)
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Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection
Chen, Paula R., Rowland, Raymond R. R., Stoian, Ana M., Petrovan, Vlad, Sheahan, Maureen, Ganta, Charan, Cino-Ozuna, Giselle, Kim, Dae Young, Dunleavey, James M., Whitworth, Kristin M., Samuel, Melissa S., Spate, Lee D., Cecil, Raissa F., Benne, Joshua A., Yan, Xingyu, Fang, Ying, Croix, Brad St, Lechtenberg, Kelly, Wells, Kevin D., Prather, Randall S.
Published in Scientific reports (23.03.2022)
Published in Scientific reports (23.03.2022)
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Genes Expressed in Human Tumor Endothelium
St. Croix, Brad, Rago, Carlo, Velculescu, Victor, Traverso, Giovanni, Romans, Katharine E., Montgomery, Elizabeth, Lal, Anita, Riggins, Gregory J., Lengauer, Christoph, Vogelstein, Bert, Kinzler, Kenneth W.
Published in Science (American Association for the Advancement of Science) (18.08.2000)
Published in Science (American Association for the Advancement of Science) (18.08.2000)
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Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis
Jiang, Qing, Qin, Xin, Yoshida, Carolina Andrea, Komori, Hisato, Yamana, Kei, Ohba, Shinsuke, Hojo, Hironori, Croix, Brad St, Kawata-Matsuura, Viviane K S, Komori, Toshihisa
Published in International journal of molecular sciences (31.03.2020)
Published in International journal of molecular sciences (31.03.2020)
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