Inward-Facing Conformation of Glutamate Transporters as Revealed by Their Inverted-Topology Structural Repeats
Crisman, Thomas J., Qu, Shaogang, Kanner, Baruch I., Forrest, Lucy R., Miller, Christopher
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2009)
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Journal Article
Identification of an Efficient Gene Expression Panel for Glioblastoma Classification
Crisman, Thomas J, Zelaya, Ivette, Laks, Dan R, Zhao, Yining, Kawaguchi, Riki, Gao, Fuying, Kornblum, Harley I, Coppola, Giovanni
Published in PloS one (17.11.2016)
Published in PloS one (17.11.2016)
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Journal Article
Large-scale assessment of the gliomasphere model system
Laks, Dan R, Crisman, Thomas J, Shih, Michelle Y S, Mottahedeh, Jack, Gao, Fuying, Sperry, Jantzen, Garrett, Matthew C, Yong, William H, Cloughesy, Timothy F, Liau, Linda M, Lai, Albert, Coppola, Giovanni, Kornblum, Harley I
Published in Neuro-oncology (Charlottesville, Va.) (01.10.2016)
Published in Neuro-oncology (Charlottesville, Va.) (01.10.2016)
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Journal Article
Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS
Omura, Takao, Omura, Kumiko, Tedeschi, Andrea, Riva, Priscilla, Painter, Michio W., Rojas, Leticia, Martin, Joshua, Lisi, Véronique, Huebner, Eric A., Latremoliere, Alban, Yin, Yuqin, Barrett, Lee B., Singh, Bhagat, Lee, Stella, Crisman, Thomas J., Gao, Fuying, Li, Songlin, Kapur, Kush, Geschwind, Daniel H., Kosik, Kenneth S., Coppola, Giovanni, He, Zhigang, Carmichael, S. Thomas, Benowitz, Larry I., Costigan, Michael, Woolf, Clifford J.
Published in Neuron (Cambridge, Mass.) (03.06.2015)
Published in Neuron (Cambridge, Mass.) (03.06.2015)
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Journal Article
Inhibition of Nucleotide Synthesis Targets Brain Tumor Stem Cells in a Subset of Glioblastoma
Laks, Dan R, Ta, Lisa, Crisman, Thomas J, Gao, Fuying, Coppola, Giovanni, Radu, Caius G, Nathanson, David A, Kornblum, Harley I
Published in Molecular cancer therapeutics (01.06.2016)
Published in Molecular cancer therapeutics (01.06.2016)
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Journal Article
A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma
Laks, Dan R, Oses-Prieto, Juan A, Alvarado, Alvaro G, Nakashima, Jonathan, Chand, Shreya, Azzam, Daniel B, Gholkar, Ankur A, Sperry, Jantzen, Ludwig, Kirsten, Condro, Michael C, Nazarian, Serli, Cardenas, Anjelica, Shih, Michelle Y S, Damoiseaux, Robert, France, Bryan, Orozco, Nicholas, Visnyei, Koppany, Crisman, Thomas J, Gao, Fuying, Torres, Jorge Z, Coppola, Giovanni, Burlingame, Alma L, Kornblum, Harley I
Published in Neuro-oncology (Charlottesville, Va.) (18.05.2018)
Published in Neuro-oncology (Charlottesville, Va.) (18.05.2018)
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Journal Article
Cysteine Scanning Mutagenesis of Transmembrane Helix 3 of a Brain Glutamate Transporter Reveals Two Conformationally Sensitive Positions
Silverstein, Nechama, Crisman, Thomas J., Forrest, Lucy R., Kanner, Baruch I.
Published in The Journal of biological chemistry (11.01.2013)
Published in The Journal of biological chemistry (11.01.2013)
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Journal Article
Ligand-Target Interaction-Based Weighting of Substructures for Virtual Screening
Crisman, Thomas J, Sisay, Mihiret T, Bajorath, Jürgen
Published in Journal of Chemical Information and Modeling (01.10.2008)
Published in Journal of Chemical Information and Modeling (01.10.2008)
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Journal Article
“Virtual Fragment Linking”: An Approach To Identify Potent Binders from Low Affinity Fragment Hits
Crisman, Thomas J, Bender, Andreas, Milik, Mariusz, Jenkins, Jeremy L, Scheiber, Josef, Sukuru, Sai Chetan K, Fejzo, Jasna, Hommel, Ulrich, Davies, John W, Glick, Meir
Published in Journal of medicinal chemistry (24.04.2008)
Published in Journal of medicinal chemistry (24.04.2008)
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Journal Article
"Plate cherry picking": a novel semi-sequential screening paradigm for cheaper, faster, information-rich compound selection
Crisman, Thomas J, Jenkins, Jeremy L, Parker, Christian N, Hill, W Adam G, Bender, Andreas, Deng, Zhan, Nettles, James H, Davies, John W, Glick, Meir
Published in Journal of biomolecular screening (01.04.2007)
Published in Journal of biomolecular screening (01.04.2007)
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Journal Article
Understanding False Positives in Reporter Gene Assays: in Silico Chemogenomics Approaches To Prioritize Cell-Based HTS Data
Crisman, Thomas J, Parker, Christian N, Jenkins, Jeremy L, Scheiber, Josef, Thoma, Mathis, Kang, Zhao Bin, Kim, Richard, Bender, Andreas, Nettles, James H, Davies, John W, Glick, Meir
Published in Journal of chemical information and modeling (01.07.2007)
Published in Journal of chemical information and modeling (01.07.2007)
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Journal Article
Which aspects of HTS are empirically correlated with downstream success?
Bender, Andreas, Bojanic, Dejan, Davies, John W, Crisman, Thomas J, Mikhailov, Dmitri, Scheiber, Josef, Jenkins, Jeremy L, Deng, Zhan, Hill, W Adam G, Popov, Maxim, Jacoby, Edgar, Glick, Meir
Published in Current opinion in drug discovery & development (01.05.2008)
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Published in Current opinion in drug discovery & development (01.05.2008)
Journal Article
Symmetry in the Structure of the Glutamate Transporter GltPh Suggests Conformation of an Alternate State
Crisman, Thomas J., Qu, Shaogang, Kanner, Baruch, Forrest, Lucy
Published in Biophysical journal (01.01.2010)
Published in Biophysical journal (01.01.2010)
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Journal Article