N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11β-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275
Siu, Michael, Johnson, Theodore O., Wang, Yong, Nair, Sajiv K., Taylor, Wendy D., Cripps, Stephan J., Matthews, Jean J., Edwards, Martin P., Pauly, Thomas A., Ermolieff, Jacques, Castro, Arturo, Hosea, Natilie A., LaPaglia, Amy, Fanjul, Andrea N., Vogel, Jennifer E.
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
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N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11β-hydroxysteroid dehydrogenase type 1: Strategies to eliminate reactive metabolites
Nair, Sajiv K., Matthews, Jean J., Cripps, Stephan J., Cheng, Hengmiao, Hoffman, Jacqui E., Smith, Christopher, Kupchinsky, Stanley, Siu, Michael, Taylor, Wendy D., Wang, Yong, Johnson, Theodore O., Dress, Klaus R., Edwards, Martin P., Zhou, Sue, Hosea, Natilie A., LaPaglia, Amy, Kang, Ping, Castro, Arturo, Ermolieff, Jacques, Fanjul, Andrea, Vogel, Jennifer E., Rejto, Paul, Dalvie, Deepak
Published in Bioorganic & medicinal chemistry letters (15.04.2013)
Published in Bioorganic & medicinal chemistry letters (15.04.2013)
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Journal Article
N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11[beta]-hydroxysteroid dehydrogenase type 1: Strategies to eliminate reactive metabolites
Nair, Sajiv K, Matthews, Jean J, Cripps, Stephan J, Cheng, Hengmiao, Hoffman, Jacqui E, Smith, Christopher, Kupchinsky, Stanley, Siu, Michael, Taylor, Wendy D, Wang, Yong, Johnson, Theodore O, Dress, Klaus R, Edwards, Martin P, Zhou, Sue, Hosea, Natilie A, LaPaglia, Amy, Kang, Ping, Castro, Arturo, Ermolieff, Jacques, Fanjul, Andrea, Vogel, Jennifer E, Rejto, Paul, Dalvie, Deepak
Published in Bioorganic & medicinal chemistry letters (15.04.2013)
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Published in Bioorganic & medicinal chemistry letters (15.04.2013)
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Novel synthesis of CP-734432, an EP4 agonist, using Sharpless asymmetric dihydroxylation
Nair, Sajiv K., Matthews, Jean J., Cripps, Stephan J., Ma, Chunrong, Dovalsantos, Elena Z., Grubbs, Alan W., Sach, Neal W., Hoeve, Wolter ten, Koster, Han, Flahive, Erik J., Tanis, Steven P., Renner, Matt, Wiltenburg, Jim van
Published in Tetrahedron letters (17.03.2010)
Published in Tetrahedron letters (17.03.2010)
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Journal Article
N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275
Siu, Michael, Johnson, Theodore O, Wang, Yong, Nair, Sajiv K, Taylor, Wendy D, Cripps, Stephan J, Matthews, Jean J, Edwards, Martin P, Pauly, Thomas A, Ermolieff, Jacques, Castro, Arturo, Hosea, Natilie A, LaPaglia, Amy, Fanjul, Andrea N, Vogel, Jennifer E
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
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Arg-Gly thiomethylene dipeptide surrogates: Synthesis and incorporation into Arg-Gly-Asp pseudotripeptides
Harn, Nancy K., Cripps, Stephan J., Rishton, Gilbert M.
Published in Tetrahedron letters (28.02.1994)
Published in Tetrahedron letters (28.02.1994)
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Novel compounds of amino sulfonyl derivatives
HUANG BUWEN, CRIPPS STEPHAN J, NAIR SAJIV K, DRESS KLAUS R, CHENG HENGMIAO, WANG YONG
Year of Publication 01.02.2007
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Year of Publication 01.02.2007
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Benzenesulfonylamino-pyridin-2-yl derivatives and related compounds as inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-hsd-1) for the treatment of diabetes and obesity
CHENG HENGMIAO,CRIPPS STEPHAN J.,EDWARDS MARTIN P.,JOHNSON THEODORE O. JR.,NAIR SAJIV K.,SIU MICHAEL,SMITH CHRISTOPHER R.,TAYLOR WENDY D.,WANG YONG
Year of Publication 17.01.2007
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Year of Publication 17.01.2007
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INDOLYL-UREA DERIVATIVES OF THIENOPYRIDINES USEFUL AS ANTI-ANGIOGENIC AGENTS
HE, MINGYING, ZHOU, RU, ROMINES, WILLIAM, III, KANIA, ROBERT, S, CRIPPS, STEPHAN, J, LOU, JIHONG
Year of Publication 08.12.2004
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Year of Publication 08.12.2004
Patent
BENZENESULFONYLAMINO-PYRIDIN-2-YL DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 (11-BETA-HSD-1) FOR THE TREATMENT OF DIABETES AND OBESITY
EDWARDS, MARTIN, P, CRIPPS, STEPHAN J, JOHNSON, THEODORE O, WANG, YONG, SMITH, CHRISTOPHER, NAIR, SAJIV K, TAYLOR, WENDY, D, CHENG, HENGMIAO, SIU, MICHAEL
Year of Publication 06.09.2006
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Year of Publication 06.09.2006
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Benzofused heteroaryl derivatives of thienopyridines useful as therapeutic agents, pharmaceutical compositions including the same, and methods for their use
JIHONG LOU, RU, DEAL, J, G, PALMER, CYNTHIA, L, ROMINES, III, WILLIAM, H, MINGYING HE, KANIA, ROBERT, S, COLLINS, MICHAEL, R, CRIPPS, STEPHAN, J
Year of Publication 31.05.2006
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Year of Publication 31.05.2006
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Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use
KANIA ROBERT S, CRIPPS STEPHAN J, PALMER CYNTHIA LOUISE, BORCHARDT ALLEN J, VARNEY MICHAEL D, COLLINS MICHAEL RAYMOND, BENDER STEVEN L, TEMPCZYK-RUSSELL ANNA MARIA
Year of Publication 09.06.2005
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Year of Publication 09.06.2005
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Novel compounds of proline and morpholine derivatives
SMITH CHRISTOPHER R, HUANG BUWEN, CRIPPS STEPHAN J, LE PHUONG T.Q, NAIR SAJIV K, HOFFMAN JACQUI E, DRESS KLAUS R, PARROTT TIMOTHY J, CHENG HENGMIAO, KUPCHINSKY STANLEY W, YANG YI, WANG YONG
Year of Publication 24.11.2005
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Year of Publication 24.11.2005
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Sulfonamide derivatives as cell adhesion modulators
ILA SIRCAR, THOMAS CHARLES MCKENZIE, STEPHAN J. CRIPPS, GILBERT RISHTON, NANCY HARN BERMAN, JAMES HU, WOLFGANG SCHOLZ
Year of Publication 30.12.1996
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Year of Publication 30.12.1996
Patent
SULFONAMIDE DERIVATIVES AS CELL ADHESION MODULATORS
SIRCAR, ILA, HU, JAMES, RISHTON, GILBERT, MCKENZIE, THOMAS, CHARLES, BERMAN, NANCY, HARN, SCHOLZ, WOLFGANG, CRIPPS, STEPHAN, J
Year of Publication 19.12.1996
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Year of Publication 19.12.1996
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INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE
HUA, YE, WALLACE, MICHAEL B, JOHNSON, THEODORE O, REICH, SIEGFRIED H, JOHNSON, MICHAEL D, KANIA, ROBERT S, BRAGANZA, JOHN F, CRIPPS, STEPHAN J, TEMPCZYK-RUSSELL, ANNA M, BENDER, STEVEN L, PALMER, CYNTHIA L, COLLINS, MICHAEL R, THOMAS, CHRISTINE, TENG, MIN, LUU, HIEP T, BORCHARDT, ALLEN J, VARNEY, MICHAEL D
Year of Publication 30.09.2002
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Year of Publication 30.09.2002
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