Defective cholesterol metabolism in amyotrophic lateral sclerosis
Abdel-Khalik, Jonas, Yutuc, Eylan, Crick, Peter J., Gustafsson, Jan-Åke, Warner, Margaret, Roman, Gustavo, Talbot, Kevin, Gray, Elizabeth, Griffiths, William J., Turner, Martin R., Wang, Yuqin
Published in Journal of lipid research (01.01.2017)
Published in Journal of lipid research (01.01.2017)
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Journal Article
Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders
Griffiths, William J., Yutuc, Eylan, Abdel-Khalik, Jonas, Crick, Peter J., Hearn, Thomas, Dickson, Alison, Bigger, Brian W., Hoi-Yee Wu, Teresa, Goenka, Anu, Ghosh, Arunabha, Jones, Simon A., Covey, Douglas F., Ory, Daniel S., Wang, Yuqin
Published in Free radical biology & medicine (20.11.2019)
Published in Free radical biology & medicine (20.11.2019)
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Journal Article
Quantitative charge-tags for sterol and oxysterol analysis
Crick, Peter J, William Bentley, T, Abdel-Khalik, Jonas, Matthews, Ian, Clayton, Peter T, Morris, Andrew A, Bigger, Brian W, Zerbinati, Chiara, Tritapepe, Luigi, Iuliano, Luigi, Wang, Yuqin, Griffiths, William J
Published in Clinical chemistry (Baltimore, Md.) (01.02.2015)
Published in Clinical chemistry (Baltimore, Md.) (01.02.2015)
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Journal Article
Quantitation of Malaria Parasite-Erythrocyte Cell-Cell Interactions Using Optical Tweezers
Crick, Alex J., Theron, Michel, Tiffert, Teresa, Lew, Virgilio L., Cicuta, Pietro, Rayner, Julian C.
Published in Biophysical journal (19.08.2014)
Published in Biophysical journal (19.08.2014)
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Journal Article
The role of microRNA-155/liver X receptor pathway in experimental and idiopathic pulmonary fibrosis
Kurowska-Stolarska, Mariola, PhD, Hasoo, Manhl K., PhD, Welsh, David J., PhD, Stewart, Lynn, BSc, McIntyre, Donna, PhD, Morton, Brian E., BSc, Johnstone, Steven, PhD, Miller, Ashley M., PhD, Asquith, Darren L., PhD, Millar, Neal L., MD, PhD, Millar, Ann B., MD, Feghali-Bostwick, Carol A., PhD, Hirani, Nikhil, MBChB, PhD, Crick, Peter J., PhD, Wang, Yuqin, PhD, Griffiths, William J., PhD, McInnes, Iain B., MD, PhD, McSharry, Charles, PhD
Published in Journal of allergy and clinical immunology (01.06.2017)
Published in Journal of allergy and clinical immunology (01.06.2017)
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Journal Article
On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO
Björkhem, Ingemar, Diczfalusy, Ulf, Lövgren-Sandblom, Anita, Starck, Lena, Jonsson, Monica, Tallman, Keri, Schirmer, Henrik, Ousager, Lilian Bomme, Crick, Peter J., Wang, Yuqin, Griffiths, William J., Guengerich, F. Peter
Published in Journal of lipid research (01.06.2014)
Published in Journal of lipid research (01.06.2014)
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Journal Article
Analytical strategies for characterization of oxysterol lipidomes: Liver X receptor ligands in plasma
Griffiths, William J., Crick, Peter J., Wang, Yuchen, Ogundare, Michael, Tuschl, Karin, Morris, Andrew A., Bigger, Brian W., Clayton, Peter T., Wang, Yuqin
Published in Free radical biology & medicine (01.06.2013)
Published in Free radical biology & medicine (01.06.2013)
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Journal Article
Developing an Enzyme-Assisted Derivatization Method for Analysis of C27 Bile Alcohols and Acids by Electrospray Ionization-Mass Spectrometry
Abdel-Khalik, Jonas, Crick, Peter J., Yutuc, Eylan, Wang, Yuqin, Griffiths, William J.
Published in Molecules (Basel, Switzerland) (07.02.2019)
Published in Molecules (Basel, Switzerland) (07.02.2019)
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Journal Article
The Cerebrospinal Fluid Profile of Cholesterol Metabolites in Parkinson's Disease and Their Association With Disease State and Clinical Features
Griffiths, William J, Abdel-Khalik, Jonas, Moore, Sarah F, Wijeyekoon, Ruwani S, Crick, Peter J, Yutuc, Eylan, Farrell, Krista, Breen, David P, Williams-Gray, Caroline H, Theofilopoulos, Spyridon, Arenas, Ernest, Trupp, Miles, Barker, Roger A, Wang, Yuqin
Published in Frontiers in aging neuroscience (30.08.2021)
Published in Frontiers in aging neuroscience (30.08.2021)
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Journal Article
An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway
Robertson, Kevin A, Hsieh, Wei Yuan, Forster, Thorsten, Blanc, Mathieu, Lu, Hongjin, Crick, Peter J, Yutuc, Eylan, Watterson, Steven, Martin, Kimberly, Griffiths, Samantha J, Enright, Anton J, Yamamoto, Mami, Pradeepa, Madapura M, Lennox, Kimberly A, Behlke, Mark A, Talbot, Simon, Haas, Jürgen, Dölken, Lars, Griffiths, William J, Wang, Yuqin, Angulo, Ana, Ghazal, Peter
Published in PLoS biology (03.03.2016)
Published in PLoS biology (03.03.2016)
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Journal Article
Automated Live Imaging Platform for Studying Merozoite Egress-Invasion in Malaria Cultures
Crick, Alex J, Tiffert, Teresa, Shah, Sheel M, Kotar, Jurij, Lew, Virgilio L, Cicuta, Pietro
Published in Biophysical journal (05.03.2013)
Published in Biophysical journal (05.03.2013)
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Journal Article
Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma
Griffiths, William J., Crick, Peter J., Meljon, Anna, Theofilopoulos, Spyridon, Abdel-Khalik, Jonas, Yutuc, Eylan, Parker, Josie E., Kelly, Diane E., Kelly, Steven L., Arenas, Ernest, Wang, Yuqin
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.02.2019)
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.02.2019)
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Journal Article
An outbreak of measles in a prison in Yorkshire, England, December 2012–January 2013
CRICK, J. R., FIRTH, R., PADFIELD, S., NEWTON, A.
Published in Epidemiology and infection (01.05.2014)
Published in Epidemiology and infection (01.05.2014)
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Journal Article
Identification of unusual oxysterols and bile acids with 7-oxo or 3β,5α,6β-trihydroxy functions in human plasma by charge-tagging mass spectrometry with multistage fragmentation[S]
Griffiths, William J., Gilmore, Ian, Yutuc, Eylan, Abdel-Khalik, Jonas, Crick, Peter J., Hearn, Thomas, Dickson, Alison, Bigger, Brian W., Wu, Teresa Hoi-Yee, Goenka, Anu, Ghosh, Arunabha, Jones, Simon A., Wang, Yuqin
Published in Journal of lipid research (01.06.2018)
Published in Journal of lipid research (01.06.2018)
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Journal Article
Formation and metabolism of oxysterols and cholestenoic acids found in the mouse circulation: Lessons learnt from deuterium-enrichment experiments and the CYP46A1 transgenic mouse
Crick, Peter J., Yutuc, Eylan, Abdel-Khalik, Jonas, Saeed, Ahmed, Betsholtz, Christer, Genove, Guillem, Björkhem, Ingemar, Wang, Yuqin, Griffiths, William J.
Published in The Journal of steroid biochemistry and molecular biology (01.12.2019)
Published in The Journal of steroid biochemistry and molecular biology (01.12.2019)
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Journal Article
Mining for Oxysterols in Cyp7b1 -/- Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5
Meljon, Anna, Crick, Peter J, Yutuc, Eylan, Yau, Joyce L, Seckl, Jonathan R, Theofilopoulos, Spyridon, Arenas, Ernest, Wang, Yuqin, Griffiths, William J
Published in Biomolecules (Basel, Switzerland) (13.04.2019)
Published in Biomolecules (Basel, Switzerland) (13.04.2019)
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Journal Article
Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates
Abdel-Khalik, Jonas, Hearn, Thomas, Dickson, Alison L., Crick, Peter J., Yutuc, Eylan, Austin-Muttitt, Karl, Bigger, Brian W., Morris, Andrew A., Shackleton, Cedric H., Clayton, Peter T., Iida, Takashi, Sircar, Ria, Rohatgi, Rajat, Marschall, Hanns-Ulrich, Sjövall, Jan, Björkhem, Ingemar, Mullins, Jonathan G.L., Griffiths, William J., Wang, Yuqin
Published in The Journal of steroid biochemistry and molecular biology (01.02.2021)
Published in The Journal of steroid biochemistry and molecular biology (01.02.2021)
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Journal Article
Sterols and oxysterols in plasma from Smith-Lemli-Opitz syndrome patients
Griffiths, William J., Abdel-Khalik, Jonas, Crick, Peter J., Ogundare, Michael, Shackleton, Cedric H., Tuschl, Karin, Kwok, Mei Kwun, Bigger, Brian W., Morris, Andrew A., Honda, Akira, Xu, Libin, Porter, Ned A., Björkhem, Ingemar, Clayton, Peter T., Wang, Yuqin
Published in The Journal of steroid biochemistry and molecular biology (01.05.2017)
Published in The Journal of steroid biochemistry and molecular biology (01.05.2017)
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Journal Article