Pharmacology of β-l-Thymidine and β-l-2′-Deoxycytidine in HepG2 Cells and Primary Human Hepatocytes: Relevance to Chemotherapeutic Efficacy against Hepatitis B Virus
HERNANDEZ-SANTIAGO, B, PLACIDI, L, DUKHAN, D, SOMMADOSSI, J. P, CRETTON-SCOTT, E, FARAJ, A, BRIDGES, E. G, BRYANT, M. L, RODRIGUEZ-ORENGO, J, IMBACH, J. L, GOSSELIN, G, PIERRA, C
Published in Antimicrobial Agents and Chemotherapy (01.06.2002)
Published in Antimicrobial Agents and Chemotherapy (01.06.2002)
Get full text
Journal Article
Antiviral l-Nucleosides Specific for Hepatitis B Virus Infection
BRYANT, Martin L, BRIDGES, Edward G, JUODAWLKIS, Amy, TENNANT, Bud, KORBA, Brent, COTE, Paul, MARION, Pat, CRETTON-SCOTT, Erika, SCHINAZI, Raymond F, SOMMADOSSI, Jean-Pierre, PLACIDI, Laurent, FARAJ, Abdesslem, LOI, Anna-Giulia, PIERRA, Claire, DUKHAN, David, GOSSELIN, Gilles, IMBACH, Jean-Louis, HERNANDEZ, Brenda
Published in Antimicrobial Agents and Chemotherapy (01.01.2001)
Published in Antimicrobial Agents and Chemotherapy (01.01.2001)
Get full text
Journal Article
Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes
Pan-Zhou, X R, Cretton-Scott, E, Zhou, X J, Xie, M Y, Rahmani, R, Schinazi, R F, Duchin, K, Sommadossi, J P
Published in Antimicrobial Agents and Chemotherapy (01.11.1997)
Published in Antimicrobial Agents and Chemotherapy (01.11.1997)
Get full text
Journal Article
67 POTENT ANTIVIRAL ACTIVITY OF SECOND GENERATION NUCLEOSIDE INHIBITORS, IDX102 AND IDX184, IN HCV-INFECTED CHIMPANZEES
Standring, D.N, Lanford, R, Cretton-Scott, E, Licklider, L, Larsson, M, Pierra, C, Gosselin, G, Perigaud, C, Surleraux, D, Mayes, B, Moussa, A, Selden, J
Published in Journal of hepatology (2008)
Published in Journal of hepatology (2008)
Get full text
Journal Article
588 IN VITRO ANTIVIRAL ACTIVITY AND PHARMACOLOGY OF IDX184, A NOVEL AND POTENT INHIBITOR OF HCV REPLICATION
Cretton-Scott, E, Perigaud, C, Peyrottes, S, Licklider, L, Camire, M, Larsson, M, La Colla, M, Hildebrand, E, Lallos, L, Bilello, J, McCarville, J, Seifer, M, Liuzzi, M, Pierra, C, Badaroux, E, Gosselin, G, Surleraux, D, Standring, D.N
Published in Journal of hepatology (2008)
Published in Journal of hepatology (2008)
Get full text
Journal Article
Monoval-LdC: Efficient Prodrug of 2′-Deoxy-β-L-cytidine (L-dC), A Potent and Selective Anti-HBV Agent
Benzaria, S., Pierra, C., Bardiot, D., Cretton-Scott, E., Bridges, E. G., Zhou, X.-J., Standring, D., Gosselin, G.
Published in Nucleosides, nucleotides & nucleic acids (01.10.2003)
Published in Nucleosides, nucleotides & nucleic acids (01.10.2003)
Get full text
Journal Article
ANTI-HBV SPECIFIC β-L-2′-DEOXYNUCLEOSIDES
Bryant, Martin L., Bridges, Edward G., Placidi, Laurent, Faraj, Abdesslem, Loi, Anna-Giulia, Pierra, Claire, Dukhan, David, Gosselin, Gilles, Imbach, Jean-Louis, Hernandez, Brenda, Juodawlkis, Amy, Tennant, Bud, Korba, Brent, Cote, Paul, Cretton-Scott, Erika, Schinazi, Raymond F., Sommadossi, Jean-Pierre
Published in Nucleosides, nucleotides & nucleic acids (01.04.2001)
Published in Nucleosides, nucleotides & nucleic acids (01.04.2001)
Get full text
Journal Article
Synthesis and Pharmacokinetics of Valopicitabine (NM283), an Efficient Prodrug of the Potent Anti-HCV Agent 2‘-C-Methylcytidine
Pierra, Claire, Amador, Agnès, Benzaria, Samira, Cretton-Scott, Erika, D'Amours, Marc, Mao, John, Mathieu, Steven, Moussa, Adel, Bridges, Edward G, Standring, David N, Sommadossi, Jean-Pierre, Storer, Richard, Gosselin, Gilles
Published in Journal of medicinal chemistry (02.11.2006)
Published in Journal of medicinal chemistry (02.11.2006)
Get full text
Journal Article
Antiviral activity and intracellular metabolism of Bis(tButyISATE) phosphotriester of beta -L-2',3' dideoxyadenosine, a potent inhibitor of HIV and HBV replication
Placidi, L, Faraj, A, Loi, A G, Pierra, C, Egron, D, Cretton-Scott, E, Gosselin, G, Perigaud, C, Martin, L T, Schinazi, R F, Imbach, J L, el Kouni, MH, Bryant, M L, Sommadossi, J P
Published in Antiviral chemistry & chemotherapy (01.03.2001)
Published in Antiviral chemistry & chemotherapy (01.03.2001)
Get full text
Journal Article
Protease Inhibitors for Patients With HIV-1 Infection: A Comparative Overview
Hughes, Peter J, Cretton-Scott, Erika, Teague, Ami, Wensel, Terri M
Published in P&T (Lawrenceville, N.J.) (01.06.2011)
Get full text
Published in P&T (Lawrenceville, N.J.) (01.06.2011)
Journal Article
Monoval-LdC: Efficient Prodrug of 2′-Deoxy-β-L-cytidine (L-dC), a Potent and Selective anti-HBV Agent
Benzaria, S., Pierra, C., Bardiot, D., Cretton-Scott, E., Bridges, E. G., Zhou, X.-J., Standring, D., Gosselin, G.
Published in ChemInform (03.02.2004)
Published in ChemInform (03.02.2004)
Get full text
Journal Article
Intracellular Metabolism of β-L-ddAMP-bis(tbutylSATE), a Potent Inhibitor of Hepatitis B Virus Replication
Faraj, A., Placidi, L., Perigaud, C., Cretton-scott, E., Gosselin, G., Martin, L. T., Pierra, C., Schinazi, R. F., Imbach, J. L., Sommadossi, J. P.
Published in Nucleosides & nucleotides (01.04.1999)
Published in Nucleosides & nucleotides (01.04.1999)
Get full text
Journal Article
NM 283 has potent antiviral activity against genotype 1 chronic hepatitis C virus (HCV-1) infection in the chimpanzee
Standring, D.N., Lanford, R., Wright, T., Chung, R.T., Bichko, V., Cretton-Scott, E., Pan-Zhou, X., Bergelson, S., Qu, L., Tausek, M., Bridges, E., Moussa, A., Storer, R., Pierra, C., Benzaria, S., Gosselin, G., La Colla, P., Sommadossi, J.P.
Published in Journal of hepatology (01.04.2003)
Published in Journal of hepatology (01.04.2003)
Get full text
Journal Article
Disposition and metabolism of the angiogenic moderator O-(chloroacetyl-carbamoyl) fumagillol (TNP-470;AGM-1470) in human hepatocytes and tissue microsomes
PLACIDI, L, CRETTON-SCOTT, E, DE SOUSA, G, RAHMANI, R, PLACIDI, M, SOMMADOSSI, J.-P
Published in Cancer research (Chicago, Ill.) (15.07.1995)
Get full text
Published in Cancer research (Chicago, Ill.) (15.07.1995)
Journal Article
Role of Human Liver P450s and Cytochrome b5 in the Reductive Metabolism of 3′-Azido-3′-deoxythymidine (AZT) to 3′-Amino-3′-deoxythymidine
Pan-Zhou, Xin-Ru, Cretton-Scott, Erika, Zhou, Xiao-Jian, Yang, Ming-Xue, Lasker, Jerome M., Sommadossi, Jean-Pierre
Published in Biochemical pharmacology (15.03.1998)
Published in Biochemical pharmacology (15.03.1998)
Get full text
Journal Article
Use of human hepatocyte primary cultures to evaluate the cellular pharmacology of anti-hepatitis agents
Cretton-Scott, E., Placidi, L., Martin, L.T., Sommadossi, J.-P.
Published in Antiviral research (01.04.1997)
Published in Antiviral research (01.04.1997)
Get full text
Journal Article
Synthesis, Biotransformation, and Pharmacokinetic Studies of 9-(β-d-Arabinofuranosyl)-6-azidopurine: A Prodrug for Ara-A Designed To Utilize the Azide Reduction Pathway
Kotra, Lakshmi P., Manouilov, Konstantine K., Cretton-Scott, Erica, Sommadossi, Jean-Pierre, Boudinot, F. Douglas, Schinazi, Raymond F., Chu, Chung K.
Published in Journal of medicinal chemistry (20.12.1996)
Published in Journal of medicinal chemistry (20.12.1996)
Get full text
Journal Article
Intracellular Metabolism of β-l-2′,3′-Dideoxyadenosine: Relevance to Its Limited Antiviral Activity
PLACIDI, L, CRETTON-SCOTT, E, GOSSELIN, G, PIERRA, C, SCHINAZI, R. F, IMBACH, J.-L, EL KOUNI, M. H, SOMMADOSSI, J.-P
Published in Antimicrobial Agents and Chemotherapy (01.04.2000)
Published in Antimicrobial Agents and Chemotherapy (01.04.2000)
Get full text
Journal Article