Myeloid‐resident neuropilin‐1 promotes choroidal neovascularization while mitigating inflammation
Andriessen, Elisabeth M M A, Binet, François, Fournier, Frédérik, Hata, Masayuki, Dejda, Agnieszka, Mawambo, Gaëlle, Crespo‐Garcia, Sergio, Pilon, Frédérique, Buscarlet, Manuel, Beauchemin, Karine, Bougie, Véronique, Cumberlidge, Garth, Wilson, Ariel M, Bourgault, Steve, Rezende, Flavio A, Beaulieu, Normand, Delisle, Jean‐Sébastien, Sapieha, Przemyslaw
Published in EMBO molecular medicine (07.05.2021)
Published in EMBO molecular medicine (07.05.2021)
Get full text
Journal Article
Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy
Binet, François, Cagnone, Gael, Crespo-Garcia, Sergio, Hata, Masayuki, Neault, Mathieu, Dejda, Agnieszka, Wilson, Ariel M., Buscarlet, Manuel, Mawambo, Gaelle Tagne, Howard, Joel P., Diaz-Marin, Roberto, Parinot, Celia, Guber, Vera, Pilon, Frédérique, Juneau, Rachel, Laflamme, Rémi, Sawchyn, Christina, Boulay, Karine, Leclerc, Severine, Abu-Thuraia, Afnan, Côté, Jean-François, Andelfinger, Gregor, Rezende, Flavio A., Sennlaub, Florian, Joyal, Jean-Sébastien, Mallette, Frédérick A., Sapieha, Przemyslaw
Published in Science (American Association for the Advancement of Science) (21.08.2020)
Published in Science (American Association for the Advancement of Science) (21.08.2020)
Get full text
Journal Article
Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition
Crespo-Garcia, Sergio, Tsuruda, Pamela R., Dejda, Agnieszka, Ryan, Rathi D., Fournier, Frederik, Chaney, Shawnta Y., Pilon, Frederique, Dogan, Taner, Cagnone, Gael, Patel, Priyanka, Buscarlet, Manuel, Dasgupta, Sonali, Girouard, Gabrielle, Rao, Surabhi R., Wilson, Ariel M., O’Brien, Robert, Juneau, Rachel, Guber, Vera, Dubrac, Alexandre, Beausejour, Christian, Armstrong, Scott, Mallette, Frederick A., Yohn, Christopher B., Joyal, Jean-Sebastien, Marquess, Dan, Beltran, Pedro J., Sapieha, Przemyslaw
Published in Cell metabolism (06.04.2021)
Published in Cell metabolism (06.04.2021)
Get full text
Journal Article
NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy
Miloudi, Khalil, Oubaha, Malika, Ménard, Catherine, Dejda, Agnieszka, Guber, Vera, Cagnone, Gael, Wilson, Ariel M., Tétreault, Nicolas, Mawambo, Gaëlle, Binet, Francois, Chidiac, Rony, Delisle, Chantal, Buscarlet, Manuel, Cerani, Agustin, Crespo-Garcia, Sergio, Bentley, Katie, Rezende, Flavio, Joyal, Jean-Sebastien, Mallette, Frédérick A., Gratton, Jean-Philippe, Larrivée, Bruno, Sapieha, Przemyslaw
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.03.2019)
Get full text
Journal Article
Anti-Inflammatory Role of Netrin-4 in Diabetic Retinopathy
Crespo-Garcia, Sergio, Reichhart, Nadine, Kociok, Norbert, Skosyrski, Sergej, Joussen, Antonia M
Published in International journal of molecular sciences (25.04.2021)
Published in International journal of molecular sciences (25.04.2021)
Get full text
Journal Article
An exploratory investigation of brain collateral circulation plasticity after cerebral ischemia in two experimental C57BL/6 mouse models
Foddis, Marco, Winek, Katarzyna, Bentele, Kajetan, Mueller, Susanne, Blumenau, Sonja, Reichhart N, Nadine, Crespo-Garcia, Sergio, Harnett, Dermot, Ivanov, Andranik, Meisel, Andreas, Joussen, Antonia, Strauss, Olaf, Beule, Dieter, Dirnagl, Ulrich, Sassi, Celeste
Published in Journal of cerebral blood flow and metabolism (01.02.2020)
Published in Journal of cerebral blood flow and metabolism (01.02.2020)
Get full text
Journal Article
Early-life peripheral infections reprogram retinal microglia and aggravate neovascular age-related macular degeneration in later life
Hata, Masayuki, Hata, Maki, Andriessen, Elisabeth Mma, Juneau, Rachel, Pilon, Frédérique, Crespo-Garcia, Sergio, Diaz-Marin, Roberto, Guber, Vera, Binet, Francois, Fournier, Frédérik, Buscarlet, Manuel, Grou, Caroline, Calderon, Virginie, Heckel, Emilie, Melichar, Heather J, Joyal, Jean-Sebastien, Wilson, Ariel M, Sapieha, Przemyslaw
Published in The Journal of clinical investigation (15.02.2023)
Published in The Journal of clinical investigation (15.02.2023)
Get full text
Journal Article
Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity
Diaz-Marin, Roberto, Crespo-Garcia, Sergio, Wilson, Ariel M., Buscarlet, Manuel, Dejda, Agnieszka, Fournier, Frédérik, Juneau, Rachel, Alquier, Thierry, Sapieha, Przemyslaw
Published in Scientific reports (03.08.2021)
Published in Scientific reports (03.08.2021)
Get full text
Journal Article
Individual and temporal variability of the retina after chronic bilateral common carotid artery occlusion (BCCAO)
Crespo-Garcia, Sergio, Reichhart, Nadine, Skosyrski, Sergej, Foddis, Marco, Wu, Jim, Figura, Aleksandar, Herrspiegel, Christina, Füchtemeier, Martina, Sassi, Celeste, Dirnagl, Ulrich, Joussen, Antonia M, Strauss, Olaf
Published in PloS one (16.03.2018)
Published in PloS one (16.03.2018)
Get full text
Journal Article
Anoctamin-4 is a bona fide Ca2+-dependent non-selective cation channel
Reichhart, Nadine, Schöberl, Simon, Keckeis, Susanne, Alfaar, Ahmad S., Roubeix, Christophe, Cordes, Magdalena, Crespo-Garcia, Sergio, Haeckel, Akvile, Kociok, Norbert, Föckler, Renate, Fels, Gabriele, Mataruga, Anja, Rauh, Robert, Milenkovic, Vladimir M., Zühlke, Kerstin, Klussmann, Enno, Schellenberger, Eyk, Strauß, Olaf
Published in Scientific reports (19.02.2019)
Published in Scientific reports (19.02.2019)
Get full text
Journal Article
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
Mawambo, Gaëlle, Oubaha, Malika, Ichiyama, Yusuke, Blot, Guillaume, Crespo-Garcia, Sergio, Dejda, Agnieszka, Binet, François, Diaz-Marin, Roberto, Sawchyn, Christina, Sergeev, Mikhail, Juneau, Rachel, Kaufman, Randal J, Affar, El Bachir, Mallette, Frédérick A, Wilson, Ariel M, Sapieha, Przemyslaw
Published in Journal of neuroinflammation (21.06.2023)
Published in Journal of neuroinflammation (21.06.2023)
Get full text
Journal Article
Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration
Roubeix, Christophe, Nous, Caroline, Augustin, Sébastien, Ronning, Kaitryn E, Mathis, Thibaud, Blond, Frédéric, Lagouge-Roussey, Pauline, Crespo-Garcia, Sergio, Sullivan, Patrick M, Gautier, Emmanuel L, Reichhart, Nadine, Sahel, José-Alain, Burns, Marie E, Paques, Michel, Sørensen, Torben Lykke, Strauss, Olaf, Guillonneau, Xavier, Delarasse, Cécile, Sennlaub, Florian
Published in Journal of neuroinflammation (17.01.2024)
Published in Journal of neuroinflammation (17.01.2024)
Get full text
Journal Article
Inhibition of Placenta Growth Factor Reduces Subretinal Mononuclear Phagocyte Accumulation in Choroidal Neovascularization
Crespo-Garcia, Sergio, Corkhill, Caitlin, Roubeix, Christophe, Davids, Anja-Maria, Kociok, Norbert, Strauss, Olaf, Joussen, Antonia M, Reichhart, Nadine
Published in Investigative ophthalmology & visual science (01.10.2017)
Published in Investigative ophthalmology & visual science (01.10.2017)
Get full text
Journal Article
Myeloid cells contribute indirectly to VEGF expression upon hypoxia via activation of Müller cells
Nürnberg, Christina, Kociok, Norbert, Brockmann, Claudia, Lischke, Timo, Crespo-Garcia, Sergio, Reichhart, Nadine, Wolf, Susanne, Baumgrass, Ria, Eming, Sabine A., Beer-Hammer, Sandra, Joussen, Antonia M.
Published in Experimental eye research (01.01.2018)
Published in Experimental eye research (01.01.2018)
Get full text
Journal Article
Correction: Individual and temporal variability of the retina after chronic bilateral common carotid artery occlusion (BCCAO)
Crespo-Garcia, Sergio, Reichhart, Nadine, Skosyrski, Sergej, Foddis, Marco, Wu, Jim, Figura, Aleksandar, Herrspiegel, Christina, Füchtemeier, Martina, Sassi, Celeste, Dirnagl, Ulrich, Joussen, Antonia M, Strauss, Olaf
Published in PloS one (23.04.2018)
Published in PloS one (23.04.2018)
Get full text
Journal Article
Dataset on the activation of Müller cells through macrophages upon hypoxia in the retina
Nürnberg, Christina, Kociok, Norbert, Brockmann, Claudia, Lischke, Timo, Crespo-Garcia, Sergio, Reichhart, Nadine, Wolf, Susanne, Baumgrass, Ria, Eming, Sabine A., Beer-Hammer, Sandra, Joussen, Antonia M.
Published in Data in brief (01.02.2018)
Published in Data in brief (01.02.2018)
Get full text
Journal Article
Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation
Hata, Masayuki, Andriessen, Elisabeth M M A, Hata, Maki, Diaz-Marin, Roberto, Fournier, Frédérik, Crespo-Garcia, Sergio, Blot, Guillaume, Juneau, Rachel, Pilon, Frédérique, Dejda, Agnieszka, Guber, Vera, Heckel, Emilie, Daneault, Caroline, Calderon, Virginie, Des Rosiers, Christine, Melichar, Heather J, Langmann, Thomas, Joyal, Jean-Sebastien, Wilson, Ariel M, Sapieha, Przemyslaw
Published in Science (American Association for the Advancement of Science) (06.01.2023)
Published in Science (American Association for the Advancement of Science) (06.01.2023)
Get full text
Journal Article
Obesity triggers tumoral senescence and renders poorly immunogenic malignancies amenable to senolysis
Fournier, Frédérik, Diaz-Marin, Roberto, Pilon, Frédérique, Neault, Mathieu, Juneau, Rachel, Girouard, Gabrielle, Wilson, Ariel M, Larrivée, Bruno, Mallette, Frédérick A, Crespo-Garcia, Sergio, Sapieha, Przemyslaw
Published in Proceedings of the National Academy of Sciences - PNAS (03.01.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (03.01.2023)
Get full text
Journal Article
Therapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results
Crespo-Garcia, Sergio, Fournier, Frédérik, Diaz-Marin, Roberto, Klier, Sharon, Ragusa, Derek, Masaki, Lauren, Cagnone, Gael, Blot, Guillaume, Hafiane, Ikhlas, Dejda, Agnieszka, Rizk, Rana, Juneau, Rachel, Buscarlet, Manuel, Chorfi, Sarah, Patel, Priyanka, Beltran, Pedro J., Joyal, Jean-Sebastien, Rezende, Flavio A., Hata, Masayuki, Nguyen, Alex, Sullivan, Lynne, Damiano, Jason, Wilson, Ariel M., Mallette, Frédérick A., David, Nathaniel E., Ghosh, Anirvan, Tsuruda, Pamela R., Dananberg, Jamie, Sapieha, Przemyslaw
Published in Nature medicine (01.02.2024)
Published in Nature medicine (01.02.2024)
Get full text
Journal Article
HIF1[alpha]-dependent hypoxia response in myeloid cells requires IRE1[alpha]
Mawambo, Gaëlle, Oubaha, Malika, Ichiyama, Yusuke, Blot, Guillaume, Crespo-Garcia, Sergio, Dejda, Agnieszka, Binet, François, Diaz-Marin, Roberto, Sawchyn, Christina, Sergeev, Mikhail, Juneau, Rachel, Kaufman, Randal J, Affar, El Bachir, Mallette, Frédérick A, Wilson, Ariel M, Sapieha, Przemyslaw
Published in Journal of neuroinflammation (21.06.2023)
Published in Journal of neuroinflammation (21.06.2023)
Get full text
Journal Article