Optimization of a Natural Product-Based Class of γ‑Secretase Modulators
Hubbs, Jed L, Fuller, Nathan O, Austin, Wesley F, Shen, Ruichao, Creaser, Steffen P, McKee, Timothy D, Loureiro, Robyn M. B, Tate, Barbara, Xia, Weiming, Ives, Jeffrey, Bronk, Brian S
Published in Journal of medicinal chemistry (08.11.2012)
Published in Journal of medicinal chemistry (08.11.2012)
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Discovery of a Novel Pharmacological and Structural Class of Gamma Secretase Modulators Derived from the Extract of Actaea racemosa
Findeis, Mark A, Schroeder, Frank, McKee, Timothy D, Yager, Debra, Fraering, Patrick C, Creaser, Steffen P, Austin, Wesley F, Clardy, Jon, Wang, Rong, Selkoe, Dennis, Eckman, Christopher B
Published in ACS chemical neuroscience (21.11.2012)
Published in ACS chemical neuroscience (21.11.2012)
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Multikilogram-Scale Production of Cycloartenol Triterpenoid Glycosides as Synthetic Intermediates for a γ‑Secretase Modulator
Shen, Ruichao, Fuller, Nathan O, Osswald, Gerd, Austin, Wesley F, Hubbs, Jed L, Haag, Dieter, Kovacs, Janos, Creaser, Steffen P, Findeis, Mark A, Ives, Jeffrey L, Bronk, Brian S
Published in Organic process research & development (20.06.2014)
Published in Organic process research & development (20.06.2014)
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Initial Optimization of a New Series of γ‑Secretase Modulators Derived from a Triterpene Glycoside
Fuller, Nathan O, Hubbs, Jed L, Austin, Wesley F, Creaser, Steffen P, McKee, Timothy D, Loureiro, Robyn M. B, Tate, Barbara, Xia, Weiming, Ives, Jeffrey L, Findeis, Mark A, Bronk, Brian S
Published in ACS medicinal chemistry letters (08.11.2012)
Published in ACS medicinal chemistry letters (08.11.2012)
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SAR investigations on a novel class of gamma-secretase modulators based on a unique scaffold
Austin, Wesley F, Hubbs, Jed L, Fuller, Nathan O, Creaser, Steffen P, McKee, Timothy D, Loureiro, Robyn M. B, Findeis, Mark A, Tate, Barbara, Ives, Jeffrey L, Bronk, Brian S
Published in MedChemComm (01.03.2013)
Published in MedChemComm (01.03.2013)
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A fluorescence-based high performance liquid chromatographic method for the characterization of palmitoyl acyl transferase activity
Varner, Amanda S, De Vos, Mackenzie L, Creaser, Steffen P, Peterson, Blake R, Smith, Charles D
Published in Analytical biochemistry (01.09.2002)
Published in Analytical biochemistry (01.09.2002)
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Design, synthesis and selection of DNA-encoded small-molecule libraries
Morgan, Barry A, Clark, Matthew A, Acharya, Raksha A, Arico-Muendel, Christopher C, Belyanskaya, Svetlana L, Benjamin, Dennis R, Carlson, Neil R, Centrella, Paolo A, Chiu, Cynthia H, Creaser, Steffen P, Cuozzo, John W, Davie, Christopher P, Ding, Yun, Franklin, G Joseph, Franzen, Kurt D, Gefter, Malcolm L, Hale, Steven P, Hansen, Nils J V, Israel, David I, Jiang, Jinwei, Kavarana, Malcolm J, Kelley, Michael S, Kollmann, Christopher S, Li, Fan, Lind, Kenneth, Mataruse, Sibongile, Medeiros, Patricia F, Messer, Jeffrey A, Myers, Paul, O'Keefe, Heather, Oliff, Matthew C, Rise, Cecil E, Satz, Alexander L, Skinner, Steven R, Svendsen, Jennifer L, Tang, Lujia, van Vloten, Kurt, Wagner, Richard W, Yao, Gang, Zhao, Baoguang
Published in Nature Chemical Biology (01.09.2009)
Published in Nature Chemical Biology (01.09.2009)
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Protein Palmitoylation Participates in PAR1-Mediated Platelet Activation
Sim, Derek S., Peterson, Blake R., Creaser, Steffen P., Flaumenhaft, Robert
Published in Blood (16.11.2004)
Published in Blood (16.11.2004)
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Erratum: Design, synthesis and selection of DNA-encoded small-molecule libraries
Clark, Matthew A, Acharya, Raksha A, Arico-Muendel, Christopher C, Belyanskaya, Svetlana L, Benjamin, Dennis R, Carlson, Neil R, Centrella, Paolo A, Chiu, Cynthia H, Creaser, Steffen P, Cuozzo, John W, Davie, Christopher P, Ding, Yun, Franklin, G Joseph, Franzen, Kurt D, Gefter, Malcolm L, Hale, Steven P, Hansen, Nils J V, Israel, David I, Jiang, Jinwei, Kavarana, Malcolm J, Kelley, Michael S, Kollmann, Christopher S, Li, Fan, Lind, Kenneth, Mataruse, Sibongile, Medeiros, Patricia F, Messer, Jeffrey A, Myers, Paul, O'Keefe, Heather, Oliff, Matthew C, Rise, Cecil E, Satz, Alexander L, Skinner, Steven R, Svendsen, Jennifer L, Tang, Lujia, van Vloten, Kurt, Wagner, Richard W, Yao, Gang, Zhao, Baoguang, Morgan, Barry A
Published in Nature chemical biology (01.10.2009)
Published in Nature chemical biology (01.10.2009)
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