Optimization of a Natural Product-Based Class of γ‑Secretase Modulators
Hubbs, Jed L, Fuller, Nathan O, Austin, Wesley F, Shen, Ruichao, Creaser, Steffen P, McKee, Timothy D, Loureiro, Robyn M. B, Tate, Barbara, Xia, Weiming, Ives, Jeffrey, Bronk, Brian S
Published in Journal of medicinal chemistry (08.11.2012)
Published in Journal of medicinal chemistry (08.11.2012)
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Journal Article
Discovery of a Novel Pharmacological and Structural Class of Gamma Secretase Modulators Derived from the Extract of Actaea racemosa
Findeis, Mark A, Schroeder, Frank, McKee, Timothy D, Yager, Debra, Fraering, Patrick C, Creaser, Steffen P, Austin, Wesley F, Clardy, Jon, Wang, Rong, Selkoe, Dennis, Eckman, Christopher B
Published in ACS chemical neuroscience (21.11.2012)
Published in ACS chemical neuroscience (21.11.2012)
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Journal Article
Multikilogram-Scale Production of Cycloartenol Triterpenoid Glycosides as Synthetic Intermediates for a γ‑Secretase Modulator
Shen, Ruichao, Fuller, Nathan O, Osswald, Gerd, Austin, Wesley F, Hubbs, Jed L, Haag, Dieter, Kovacs, Janos, Creaser, Steffen P, Findeis, Mark A, Ives, Jeffrey L, Bronk, Brian S
Published in Organic process research & development (20.06.2014)
Published in Organic process research & development (20.06.2014)
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Journal Article
Initial Optimization of a New Series of γ‑Secretase Modulators Derived from a Triterpene Glycoside
Fuller, Nathan O, Hubbs, Jed L, Austin, Wesley F, Creaser, Steffen P, McKee, Timothy D, Loureiro, Robyn M. B, Tate, Barbara, Xia, Weiming, Ives, Jeffrey L, Findeis, Mark A, Bronk, Brian S
Published in ACS medicinal chemistry letters (08.11.2012)
Published in ACS medicinal chemistry letters (08.11.2012)
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Journal Article
SAR investigations on a novel class of gamma-secretase modulators based on a unique scaffold
Austin, Wesley F, Hubbs, Jed L, Fuller, Nathan O, Creaser, Steffen P, McKee, Timothy D, Loureiro, Robyn M. B, Findeis, Mark A, Tate, Barbara, Ives, Jeffrey L, Bronk, Brian S
Published in MedChemComm (01.03.2013)
Published in MedChemComm (01.03.2013)
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Journal Article
A fluorescence-based high performance liquid chromatographic method for the characterization of palmitoyl acyl transferase activity
Varner, Amanda S, De Vos, Mackenzie L, Creaser, Steffen P, Peterson, Blake R, Smith, Charles D
Published in Analytical biochemistry (01.09.2002)
Published in Analytical biochemistry (01.09.2002)
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Journal Article
Design, synthesis and selection of DNA-encoded small-molecule libraries
Morgan, Barry A, Clark, Matthew A, Acharya, Raksha A, Arico-Muendel, Christopher C, Belyanskaya, Svetlana L, Benjamin, Dennis R, Carlson, Neil R, Centrella, Paolo A, Chiu, Cynthia H, Creaser, Steffen P, Cuozzo, John W, Davie, Christopher P, Ding, Yun, Franklin, G Joseph, Franzen, Kurt D, Gefter, Malcolm L, Hale, Steven P, Hansen, Nils J V, Israel, David I, Jiang, Jinwei, Kavarana, Malcolm J, Kelley, Michael S, Kollmann, Christopher S, Li, Fan, Lind, Kenneth, Mataruse, Sibongile, Medeiros, Patricia F, Messer, Jeffrey A, Myers, Paul, O'Keefe, Heather, Oliff, Matthew C, Rise, Cecil E, Satz, Alexander L, Skinner, Steven R, Svendsen, Jennifer L, Tang, Lujia, van Vloten, Kurt, Wagner, Richard W, Yao, Gang, Zhao, Baoguang
Published in Nature Chemical Biology (01.09.2009)
Published in Nature Chemical Biology (01.09.2009)
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Journal Article
P1‐028: Gamma—secretase modulators do not show a potency shift in high expressing model systems
Bronk, Brian, Tate, Barbara, Loureiro, Robyn, Austin, Wesley, Creaser, Steffen, Fuller, Nathan, Hubbs, Jed
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
Gamma—secretase modulators do not show a potency shift in high expressing model systems
Bronk, Brian, Tate, Barbara, Loureiro, Robyn, Austin, Wesley, Creaser, Steffen, Fuller, Nathan, Hubbs, Jed
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
Classification of γ-secretase modulators and their effect on pharmacological profiles of amyloid β peptides
Xia, Weiming, McKee, Timothy, Loureiro, Robyn, Austin, Wesley, Bronk, Brian, Creaser, Steffen, Fuller, Nathan, Hubbs, Jed, Pojasek, Kevin, Tate, Barbara
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
P2‐513: Classification of γ‐secretase modulators and their effect on pharmacological profiles of amyloid β peptides
Xia, Weiming, McKee, Timothy, Loureiro, Robyn, Austin, Wesley, Bronk, Brian, Creaser, Steffen, Fuller, Nathan, Hubbs, Jed, Pojasek, Kevin, Tate, Barbara
Published in Alzheimer's & dementia (01.07.2011)
Published in Alzheimer's & dementia (01.07.2011)
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Journal Article
Protein Palmitoylation Participates in PAR1-Mediated Platelet Activation
Sim, Derek S., Peterson, Blake R., Creaser, Steffen P., Flaumenhaft, Robert
Published in Blood (16.11.2004)
Published in Blood (16.11.2004)
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Journal Article
Erratum: Design, synthesis and selection of DNA-encoded small-molecule libraries
Clark, Matthew A, Acharya, Raksha A, Arico-Muendel, Christopher C, Belyanskaya, Svetlana L, Benjamin, Dennis R, Carlson, Neil R, Centrella, Paolo A, Chiu, Cynthia H, Creaser, Steffen P, Cuozzo, John W, Davie, Christopher P, Ding, Yun, Franklin, G Joseph, Franzen, Kurt D, Gefter, Malcolm L, Hale, Steven P, Hansen, Nils J V, Israel, David I, Jiang, Jinwei, Kavarana, Malcolm J, Kelley, Michael S, Kollmann, Christopher S, Li, Fan, Lind, Kenneth, Mataruse, Sibongile, Medeiros, Patricia F, Messer, Jeffrey A, Myers, Paul, O'Keefe, Heather, Oliff, Matthew C, Rise, Cecil E, Satz, Alexander L, Skinner, Steven R, Svendsen, Jennifer L, Tang, Lujia, van Vloten, Kurt, Wagner, Richard W, Yao, Gang, Zhao, Baoguang, Morgan, Barry A
Published in Nature chemical biology (01.10.2009)
Published in Nature chemical biology (01.10.2009)
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Journal Article
COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS
CREASER STEFFEN PHILLIP, AUSTIN WESLEY FRANCIS, SHEN RUICHAO, FULLER NATHAN OLIVER, HUBBS JED LEE, FINDEIS MARK ARTHUR, BRONK BRIAN SCOTT, IVES JEFFREY LEE
Year of Publication 18.12.2012
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Year of Publication 18.12.2012
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