Cyclic Peptide Screening Methods for Preclinical Drug Discovery
Li, Xinting, Craven, Timothy W, Levine, Paul M
Published in Journal of medicinal chemistry (22.09.2022)
Published in Journal of medicinal chemistry (22.09.2022)
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Journal Article
Effects of Intensive BP Control in CKD
Cheung, Alfred K, Rahman, Mahboob, Reboussin, David M, Craven, Timothy E, Greene, Tom, Kimmel, Paul L, Cushman, William C, Hawfield, Amret T, Johnson, Karen C, Lewis, Cora E, Oparil, Suzanne, Rocco, Michael V, Sink, Kaycee M, Whelton, Paul K, Wright, Jr, Jackson T, Basile, Jan, Beddhu, Srinivasan, Bhatt, Udayan, Chang, Tara I, Chertow, Glenn M, Chonchol, Michel, Freedman, Barry I, Haley, William, Ix, Joachim H, Katz, Lois A, Killeen, Anthony A, Papademetriou, Vasilios, Ricardo, Ana C, Servilla, Karen, Wall, Barry, Wolfgram, Dawn, Yee, Jerry
Published in Journal of the American Society of Nephrology (01.09.2017)
Published in Journal of the American Society of Nephrology (01.09.2017)
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Journal Article
Comprehensive computational design of ordered peptide macrocycles
Hosseinzadeh, Parisa, Bhardwaj, Gaurav, Mulligan, Vikram Khipple, Shortridge, Matthew D., Craven, Timothy W., Pardo-Avila, Fátima, Rettie, Stephen A., Kim, David E., Silva, Daniel-Adriano, Ibrahim, Yehia M., Webb, Ian K., Cort, John R., Adkins, Joshua N., Varani, Gabriele, Baker, David
Published in Science (American Association for the Advancement of Science) (15.12.2017)
Published in Science (American Association for the Advancement of Science) (15.12.2017)
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Journal Article
Effects of intensive glucose control on microvascular outcomes in patients with type 2 diabetes: a meta-analysis of individual participant data from randomised controlled trials
Zoungas, Sophia, Prof, Arima, Hisatomi, Prof, Gerstein, Hertzel C, Prof, Holman, Rury R, Prof, Woodward, Mark, Prof, Reaven, Peter, Prof, Hayward, Rodney A, Prof, Craven, Timothy, MSPH, Coleman, Ruth L, MSc, Chalmers, John, Prof
Published in The lancet. Diabetes & endocrinology (01.06.2017)
Published in The lancet. Diabetes & endocrinology (01.06.2017)
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Journal Article
The Sulfur-Linked Analogue of O‑GlcNAc (S-GlcNAc) Is an Enzymatically Stable and Reasonable Structural Surrogate for O‑GlcNAc at the Peptide and Protein Levels
De Leon, Cesar A, Levine, Paul M, Craven, Timothy W, Pratt, Matthew R
Published in Biochemistry (Easton) (11.07.2017)
Published in Biochemistry (Easton) (11.07.2017)
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Journal Article
O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity
Balana, Aaron T., Levine, Paul M., Craven, Timothy W., Mukherjee, Somnath, Pedowitz, Nichole J., Moon, Stuart P., Takahashi, Terry T., Becker, Christian F. W., Baker, David, Pratt, Matthew R.
Published in Nature chemistry (01.05.2021)
Published in Nature chemistry (01.05.2021)
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Journal Article
Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer
Schneider, Jeffrey A., Craven, Timothy W., Kasper, Amanda C., Yun, Chi, Haugbro, Michael, Briggs, Erica M., Svetlov, Vladimir, Nudler, Evgeny, Knaut, Holger, Bonneau, Richard, Garabedian, Michael J., Kirshenbaum, Kent, Logan, Susan K.
Published in Nature communications (23.10.2018)
Published in Nature communications (23.10.2018)
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Journal Article
Effects of Intensive Blood Pressure Lowering on Kidney Tubule Injury in CKD: A Longitudinal Subgroup Analysis in SPRINT
Malhotra, Rakesh, Craven, Timothy, Ambrosius, Walter T., Killeen, Anthony A., Haley, William E., Cheung, Alfred K., Chonchol, Michel, Sarnak, Mark, Parikh, Chirag R., Shlipak, Michael G., Ix, Joachim H.
Published in American journal of kidney diseases (01.01.2019)
Published in American journal of kidney diseases (01.01.2019)
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Journal Article
Accurate de novo design of membrane-traversing macrocycles
Bhardwaj, Gaurav, O’Connor, Jacob, Rettie, Stephen, Huang, Yen-Hua, Ramelot, Theresa A., Mulligan, Vikram Khipple, Alpkilic, Gizem Gokce, Palmer, Jonathan, Bera, Asim K., Bick, Matthew J., Di Piazza, Maddalena, Li, Xinting, Hosseinzadeh, Parisa, Craven, Timothy W., Tejero, Roberto, Lauko, Anna, Choi, Ryan, Glynn, Calina, Dong, Linlin, Griffin, Robert, van Voorhis, Wesley C., Rodriguez, Jose, Stewart, Lance, Montelione, Gaetano T., Craik, David, Baker, David
Published in Cell (15.09.2022)
Published in Cell (15.09.2022)
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Journal Article
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
Hosseinzadeh, Parisa, Watson, Paris R., Craven, Timothy W., Li, Xinting, Rettie, Stephen, Pardo-Avila, Fátima, Bera, Asim K., Mulligan, Vikram Khipple, Lu, Peilong, Ford, Alexander S., Weitzner, Brian D., Stewart, Lance J., Moyer, Adam P., Di Piazza, Maddalena, Whalen, Joshua G., Greisen, Per Jr, Christianson, David W., Baker, David
Published in Nature communications (07.06.2021)
Published in Nature communications (07.06.2021)
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Journal Article
Grip strength measurement for frailty assessment in patients with vascular disease and associations with comorbidity, cardiac risk, and sarcopenia
Reeve, Thomas E., Ur, Rebecca, Craven, Timothy E., Kaan, James H., Goldman, Matthew P., Edwards, Matthew S., Hurie, Justin B., Velazquez-Ramirez, Gabriela, Corriere, Matthew A.
Published in Journal of vascular surgery (01.05.2018)
Published in Journal of vascular surgery (01.05.2018)
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Journal Article
Kidney Damage Biomarkers and Incident Chronic Kidney Disease During Blood Pressure Reduction: A Case-Control Study
Zhang, William R, Craven, Timothy E, Malhotra, Rakesh, Cheung, Alfred K, Chonchol, Michel, Drawz, Paul, Sarnak, Mark J, Parikh, Chirag R, Shlipak, Michael G, Ix, Joachim H
Published in Annals of internal medicine (06.11.2018)
Published in Annals of internal medicine (06.11.2018)
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Journal Article
Effect of Intensive Glycemic Control on Risk of Lower Extremity Amputation
Goldman, Matthew P., Clark, Christopher J., Craven, Timothy E., Davis, Ross P., Williams, Timothy K., Velazquez-Ramirez, Gabriela, Hurie, Justin B., Edwards, Matthew S.
Published in Journal of the American College of Surgeons (01.12.2018)
Published in Journal of the American College of Surgeons (01.12.2018)
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Journal Article
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
Mulligan, Vikram Khipple, Workman, Sean, Sun, Tianjun, Rettie, Stephen, Li, Xinting, Worrall, Liam J., Craven, Timothy W., King, Dustin T., Hosseinzadeh, Parisa, Watkins, Andrew M., Renfrew, P. Douglas, Guffy, Sharon, Labonte, Jason W., Moretti, Rocco, Bonneau, Richard, Strynadka, Natalie C. J., Baker, David
Published in Proceedings of the National Academy of Sciences - PNAS (23.03.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (23.03.2021)
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Journal Article
PPII Helical Peptidomimetics Templated by Cation-π Interactions
Craven, Timothy W., Bonneau, Richard, Kirshenbaum, Kent
Published in Chembiochem : a European journal of chemical biology (04.10.2016)
Published in Chembiochem : a European journal of chemical biology (04.10.2016)
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Journal Article
A Miniature Protein Stabilized by a Cation−π Interaction Network
Craven, Timothy W, Cho, Min-Kyu, Traaseth, Nathaniel J, Bonneau, Richard, Kirshenbaum, Kent
Published in Journal of the American Chemical Society (10.02.2016)
Published in Journal of the American Chemical Society (10.02.2016)
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Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor
Muratspahić, Edin, Deibler, Kristine, Han, Jianming, Tomašević, Nataša, Jadhav, Kirtikumar B., Olivé-Marti, Aina-Leonor, Hochrainer, Nadine, Hellinger, Roland, Koehbach, Johannes, Fay, Jonathan F., Rahman, Mohammad Homaidur, Hegazy, Lamees, Craven, Timothy W., Varga, Balazs R., Bhardwaj, Gaurav, Appourchaux, Kevin, Majumdar, Susruta, Muttenthaler, Markus, Hosseinzadeh, Parisa, Craik, David J., Spetea, Mariana, Che, Tao, Baker, David, Gruber, Christian W.
Published in Nature communications (06.12.2023)
Published in Nature communications (06.12.2023)
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Journal Article
Effects of Intensive Systolic Blood Pressure Control on Kidney and Cardiovascular Outcomes in Persons Without Kidney Disease: A Secondary Analysis of a Randomized Trial
Beddhu, Srinivasan, Rocco, Michael V, Toto, Robert, Craven, Timothy E, Greene, Tom, Bhatt, Udayan, Cheung, Alfred K, Cohen, Debbie, Freedman, Barry I, Hawfield, Amret T, Killeen, Anthony A, Kimmel, Paul L, Lash, James, Papademetriou, Vasilios, Rahman, Mahboob, Rastogi, Anjay, Servilla, Karen, Townsend, Raymond R, Wall, Barry, Whelton, Paul K
Published in Annals of internal medicine (19.09.2017)
Published in Annals of internal medicine (19.09.2017)
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Journal Article
Isolating Conformers to Assess Dynamics of Peptidic Catalysts Using Computationally Designed Macrocyclic Peptides
Stone, Elizabeth A, Hosseinzadeh, Parisa, Craven, Timothy W, Robertson, Michael J, Han, Yaodong, Hsieh, Sheng-Ying, Metrano, Anthony J, Baker, David, Miller, Scott J
Published in ACS catalysis (16.04.2021)
Published in ACS catalysis (16.04.2021)
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