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Jacobsen, J. Steven, Comery, Thomas A, Martone, Robert L, Elokdah, Hassan, Crandall, David L, Oganesian, Aram, Aschmies, Suzan, Kirksey, Yolanda, Gonzales, Cathleen, Xu, Jane, Zhou, Hua, Atchison, Kevin, Wagner, Erik, Zaleska, Margaret M, Das, Indranil, Arias, Robert L, Bard, Jonathan, Riddell, David, Gardell, Stephen J, Abou-Gharbia, Magid, Robichaud, Albert, Magolda, Ronald, Vlasuk, George P, Bjornsson, Thorir, Reinhart, Peter H, Pangalos, Menelas N
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2008)
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Mechanism of Inactivation of Plasminogen Activator Inhibitor-1 by a Small Molecule Inhibitor
Gorlatova, Natalia V., Cale, Jacqueline M., Elokdah, Hassan, Li, Donghua, Fan, Kristi, Warnock, Mark, Crandall, David L., Lawrence, Daniel A.
Published in The Journal of biological chemistry (23.03.2007)
Published in The Journal of biological chemistry (23.03.2007)
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Comparative effects of urocortins and stresscopin on cardiac myocyte contractility
Makarewich, Catherine A, Troupes, Constantine D, Schumacher, Sarah M, Gross, Polina, Koch, Walter J, Crandall, David L, Houser, Steven R
Published in Journal of molecular and cellular cardiology (01.09.2015)
Published in Journal of molecular and cellular cardiology (01.09.2015)
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Tiplaxtinin, a Novel, Orally Efficacious Inhibitor of Plasminogen Activator Inhibitor-1: Design, Synthesis, and Preclinical Characterization
Elokdah, Hassan, Abou-Gharbia, Magid, Hennan, James K, McFarlane, Geraldine, Mugford, Cheryl P, Krishnamurthy, Girija, Crandall, David L
Published in Journal of medicinal chemistry (01.07.2004)
Published in Journal of medicinal chemistry (01.07.2004)
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Modulation of Adipose Tissue Development by Pharmacological Inhibition of PAI-1
Crandall, David L, Quinet, Elaine M, El Ayachi, Soulaf, Hreha, Amy L, Leik, Courtney E, Savio, Dawn A, Juhan-Vague, Irene, Alessi, Marie-Christine
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2006)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2006)
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Pharmacological Inhibition and Genetic Deficiency of Plasminogen Activator Inhibitor-1 Attenuates Angiotensin II/Salt-Induced Aortic Remodeling
Weisberg, Alec D, Albornoz, Francisco, Griffin, Jane P, Crandall, David L, Elokdah, Hassan, Fogo, Agnes B, Vaughan, Douglas E, Brown, Nancy J
Published in Arteriosclerosis, thrombosis, and vascular biology (01.02.2005)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.02.2005)
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Effects of Pharmacological Inhibition and Genetic Deficiency of Plasminogen Activator Inhibitor-1 in Radiation-Induced Intestinal Injury
Abderrahmani, Rym, M.S, François, Agnès, Ph.D, Buard, Valérie, B.S, Benderitter, Marc, Ph.D, Sabourin, Jean-Christophe, M.D., Ph.D, Crandall, David L., Ph.D, Milliat, Fabien, Ph.D
Published in International journal of radiation oncology, biology, physics (01.07.2009)
Published in International journal of radiation oncology, biology, physics (01.07.2009)
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Rotigaptide (ZP123) Prevents Spontaneous Ventricular Arrhythmias and Reduces Infarct Size During Myocardial Ischemia/Reperfusion Injury in Open-Chest Dogs
Hennan, James K, Swillo, Robert E, Morgan, Gwen A, Keith, Jr, James C, Schaub, Robert G, Smith, Robert P, Feldman, Hal S, Haugan, Ketil, Kantrowitz, Joel, Wang, Phil J, Abu-Qare, Aqel, Butera, John, Larsen, Bjarne D, Crandall, David L
Published in The Journal of pharmacology and experimental therapeutics (01.04.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2006)
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Neutralization of Plasminogen Activator Inhibitor I (PAI-1) by the Synthetic Antagonist PAI-749 via a Dual Mechanism of Action
Gardell, Stephen J, Krueger, Julie A, Antrilli, Thomas A, Elokdah, Hassan, Mayer, Scott, Orcutt, Steven J, Crandall, David L, Vlasuk, George P
Published in Molecular pharmacology (01.10.2007)
Published in Molecular pharmacology (01.10.2007)
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Characterization of the Novel P-Selectin Inhibitor PSI-697 [2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h] Quinoline-4-carboxylic acid] in Vitro and in Rodent Models of Vascular Inflammation and Thrombosis
Bedard, Patricia W, Clerin, Valerie, Sushkova, Natalia, Tchernychev, Boris, Antrilli, Thomas, Resmini, Christine, Keith, Jr, James C, Hennan, James K, Kaila, Neelu, Debernardo, Silvano, Janz, Kristin, Wang, Qin, Crandall, David L, Schaub, Robert G, Shaw, Gray D, Carter, Laura L
Published in The Journal of pharmacology and experimental therapeutics (01.02.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2008)
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Evaluation of PAI-039 [{1-Benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic Acid], a Novel Plasminogen Activator Inhibitor-1 Inhibitor, in a Canine Model of Coronary Artery Thrombosis
Hennan, James K, Elokdah, Hassan, Leal, Mauricio, Ji, Allena, Friedrichs, Gregory S, Morgan, Gwen A, Swillo, Robert E, Antrilli, Thomas M, Hreha, Amy, Crandall, David L
Published in The Journal of pharmacology and experimental therapeutics (01.08.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2005)
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Pharmacologic inhibition of platelet vWF-GPIb alpha interaction prevents coronary artery thrombosis
Hennan, James K, Swillo, Robert E, Morgan, Gwen A, Leik, Courtney E, Brooks, Jonathan M, Shaw, Gray D, Schaub, Robert G, Crandall, David L, Vlasuk, George P
Published in Thrombosis and haemostasis (01.03.2006)
Published in Thrombosis and haemostasis (01.03.2006)
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Synthesis and SAR of 2-carboxylic acid indoles as inhibitors of plasminogen activator inhibitor-1
Hu, Baihua, Jetter, James W., Wrobel, Jay E., Antrilli, Thomas M., Bauer, Jean S., Di, Li, Polakowski, Sergiusz, Jain, Uday, Crandall, David L.
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
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Design and synthesis of oxadiazolidinediones as inhibitors of plasminogen activator inhibitor-1
Gopalsamy, Ariamala, Kincaid, Scott L., Ellingboe, John W., Groeling, Thomas M., Antrilli, Thomas M., Krishnamurthy, Girija, Aulabaugh, Ann, Friedrichs, Gregory S., Crandall, David L.
Published in Bioorganic & medicinal chemistry letters (05.07.2004)
Published in Bioorganic & medicinal chemistry letters (05.07.2004)
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Synthesis and evaluation of azabicyclo[3.2.1]octane derivatives as potent mixed vasopressin antagonists
Crombie, Aimee L., Antrilli, Thomas M., Campbell, Brandon A., Crandall, David L., Failli, Amedeo A., He, Yanan, Kern, Jeffrey C., Moore, William J., Nogle, Lisa M., Trybulski, Eugene J.
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
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p38 mitogen-activated protein kinase-dependent tumor necrosis factor-alpha-converting enzyme is important for liver injury in hepatotoxic interaction between lipopolysaccharide and ranitidine
Deng, Xiaomin, Lu, Jingtao, Lehman-McKeeman, Lois D, Malle, Ernst, Crandall, David L, Ganey, Patricia E, Roth, Robert A
Published in The Journal of pharmacology and experimental therapeutics (01.07.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2008)
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Angiotensin II Receptors in Human Preadipocytes: Role in Cell Cycle Regulation
Crandall, David L, Armellino, Douglas C, Busler, Dennis E, McHendry-Rinde, Barbara, Kral, John G
Published in Endocrinology (Philadelphia) (01.01.1999)
Published in Endocrinology (Philadelphia) (01.01.1999)
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