Oral bioavailability of a poorly water soluble HIV-1 protease inhibitor incorporated into pH-sensitive particles: effect of the particle size and nutritional state
De Jaeghere, F., Allémann, E., Kubel, F., Galli, B., Cozens, R., Doelker, E., Gurny, R.
Published in Journal of controlled release (10.08.2000)
Published in Journal of controlled release (10.08.2000)
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261 Effects of isoflurane anesthesia on bioluminescence measurements: impact on pharmacological assessment of anti-tumor activity of chemical entities
Schnell, C, Arnal, S, Barbé, S, Becquet, M, Garcia-Echeverria, C, Cozens, R
Published in European journal of cancer supplements (2010)
Published in European journal of cancer supplements (2010)
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pH-sensitive nanoparticles: an effective means to improve the oral delivery of HIV-1 protease inhibitors in dogs
Leroux, J C, Cozens, R M, Roesel, J L, Galli, B, Doelker, E, Gurny, R
Published in Pharmaceutical research (01.03.1996)
Published in Pharmaceutical research (01.03.1996)
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9-(2-Phosphonylmethoxyethyl)adenine in the treatment of murine acquired immunodeficiency disease and opportunistic herpes simplex virus infections
GANGEMI, J. D, COZENS, R. M, DE CLERCQ, E, BALZARINI, J, HOCHKEPPEL, H.-K
Published in Antimicrobial Agents and Chemotherapy (01.11.1989)
Published in Antimicrobial Agents and Chemotherapy (01.11.1989)
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A potent protein‐tyrosine kinase inhibitor which selectively blocks proliferation of epidermal growth factor receptor‐expressing tumor cells in vitro and in vivo
Lydon, Nicholas B., Mett, Helmut, Mueller, Marcel, Becker, Michael, Cozens, Robert M., Stover, David, Daniels, Daren, Traxler, Peter, Buchdunger, Elisabeth
Published in International journal of cancer (30.03.1998)
Published in International journal of cancer (30.03.1998)
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CGP 53437, an orally bioavailable inhibitor of human immunodeficiency virus type 1 protease with potent antiviral activity
ALTERI, E, BOLD, G, WALKER, M, WOODS-COOK, K, COZENS, R, FAESSLER, A, KLIMKAIT, T, LANG, M, LAZDINS, J, PONCIONI, B, ROESEL, J. L, SCHNEIDER, P
Published in Antimicrobial Agents and Chemotherapy (01.10.1993)
Published in Antimicrobial Agents and Chemotherapy (01.10.1993)
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AEE788: A dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity
TRAXLER, Peter, ALLEGRINI, Peter R, MEYER, Thomas, TANG, Careen, WARTMANN, Markus, WOOD, Jeanette, CARAVATTI, Giorgio, BRANDT, Ralf, BRUEGGEN, Josef, COZENS, Robert, FABBRO, Doriano, GROSIOS, Konstantina, LANE, Heidi A, MCSHEEHY, Paul, MESTAN, Jürgen
Published in Cancer research (Chicago, Ill.) (15.07.2004)
Published in Cancer research (Chicago, Ill.) (15.07.2004)
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In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase
Garcı́a-Echeverrı́a, Carlos, Pearson, Mark A, Marti, Andreas, Meyer, Thomas, Mestan, Juergen, Zimmermann, Johann, Gao, Jiaping, Brueggen, Josef, Capraro, Hans-Georg, Cozens, Robert, Evans, Dean B, Fabbro, Doriano, Furet, Pascal, Porta, Diana Graus, Liebetanz, Janis, Martiny-Baron, Georg, Ruetz, Stephan, Hofmann, Francesco
Published in Cancer cell (01.03.2004)
Published in Cancer cell (01.03.2004)
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Author errata
Lydon, N, Mett, H, Mueller, M, Becker, M, Cozens, R M, Daniels, D, Traxler, P, Buchdunger, E, Stover, D
Published in International journal of cancer (17.05.1999)
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Published in International journal of cancer (17.05.1999)
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Synthesis and Pharmacological Evaluation of CGP 57813 and CGP 61755, HIV-1 Protease Inhibitors from the Phe-c-Phe Peptidomimetic Class
Cozens, R.M., Bold, G., Capraro, H-G., Fässler, A., Mestan, J., Lang, M., Poncioni, B., Stover, D., Rösel, J.L.
Published in Antiviral chemistry & chemotherapy (01.12.1996)
Published in Antiviral chemistry & chemotherapy (01.12.1996)
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PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
WOOD, J. M, BOLD, G, PERSOHN, E, RÖSEL, J, SCHNELL, C, STOVER, D, THEUER, A, TOWBIN, H, WENGER, F, WOODS-COOK, K, MENRAD, A, SIEMEISTER, G, BUCHDUNGER, E, SCHIRNER, M, THIERAUCH, K.-H, SCHNEIDER, M. R, DREVS, J, MARTINY-BARON, G, TOTZKE, F, MARME, D, COZENS, R, FERRARI, S, FREI, J, HOFMANN, F, MESTAN, J, METT, H, O'REILLY, T
Published in Cancer research (Chicago, Ill.) (15.04.2000)
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Published in Cancer research (Chicago, Ill.) (15.04.2000)
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Ex Vivo anti-HIV Activity of Human Serum Obtained from Normal Volunteers Following Oral Administration of the HIV-1 Protease Inhibitor CGP 53437: Value as Predictor of Antiviral Efficacy
Lazdins, JK, Walker, JK, Cozens, RM, Flesch, G, Czendlik, C, Howald, H, Kremers, W, Alteri, E
Published in Antiviral chemistry & chemotherapy (01.02.1997)
Published in Antiviral chemistry & chemotherapy (01.02.1997)
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