A MALT1 inhibitor suppresses human myeloid DC, effector T-cell and B-cell responses and retains Th1/regulatory T-cell homeostasis
Dumont, Celine, Sivars, Ulf, Andreasson, Theresa, Odqvist, Lina, Mattsson, Johan, DeMicco, Amy, Pardali, Katerina, Johansson, Gustav, Yrlid, Linda, Cox, Rhona J, Seeliger, Frank, Larsson, Marie, Gehrmann, Ulf, Davis, Andrew M, Vaarala, Outi
Published in PloS one (01.09.2020)
Published in PloS one (01.09.2020)
Get full text
Journal Article
Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs
Gardiner, Philip, Cox, Rhona J, Grime, Ken
Published in Drug metabolism and disposition (01.08.2019)
Published in Drug metabolism and disposition (01.08.2019)
Get full text
Journal Article
N‑Trifluoromethyl Amines and Azoles: An Underexplored Functional Group in the Medicinal Chemist’s Toolbox
Schiesser, Stefan, Chepliaka, Hanna, Kollback, Johanna, Quennesson, Thibaut, Czechtizky, Werngard, Cox, Rhona J
Published in Journal of medicinal chemistry (12.11.2020)
Published in Journal of medicinal chemistry (12.11.2020)
Get full text
Journal Article
Asymmetric, Stereocontrolled Total Synthesis of Paraherquamide A
Williams, Robert M, Cao, Jianhua, Tsujishima, Hidekazu, Cox, Rhona J
Published in Journal of the American Chemical Society (08.10.2003)
Published in Journal of the American Chemical Society (08.10.2003)
Get full text
Journal Article
The powerful symbiosis between synthetic and medicinal chemistry
Schiesser, Stefan, Cox, Rhona J, Czechtizky, Werngard
Published in Future medicinal chemistry (01.06.2021)
Published in Future medicinal chemistry (01.06.2021)
Get full text
Journal Article
Discovery and optimization of cyclohexane-1,4-diamines as allosteric MALT1 inhibitors
Schiesser, Stefan, Hajek, Peter, Pople, Huw E., Käck, Helena, Öster, Linda, Cox, Rhona J.
Published in European journal of medicinal chemistry (05.01.2022)
Published in European journal of medicinal chemistry (05.01.2022)
Get full text
Journal Article
Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3‑Kinase (PI3K)‑γ Inhibitors
Pemberton, Nils, Mogemark, Mickael, Arlbrandt, Susanne, Bold, Peter, Cox, Rhona J, Gardelli, Cristina, Holden, Neil S, Karabelas, Kostas, Karlsson, Johan, Lever, Sarah, Li, Xueshan, Lindmark, Helena, Norberg, Monica, Perry, Matthew W. D, Petersen, Jens, Rodrigo Blomqvist, Sandra, Thomas, Matthew, Tyrchan, Christian, Westin Eriksson, Annika, Zlatoidsky, Pavol, Öster, Linda
Published in Journal of medicinal chemistry (28.06.2018)
Published in Journal of medicinal chemistry (28.06.2018)
Get full text
Journal Article
Efficacious Inhaled PDE4 Inhibitors with Low Emetic Potential and Long Duration of Action for the Treatment of COPD
De Savi, Chris, Cox, Rhona J, Warner, Daniel J, Cook, Anthony R, Dickinson, Mark R, McDonough, Amy, Morrill, Louis C, Parker, Beth, Andrews, Glen, Young, Simon S, Gilmour, Peter S, Riley, Rob, Dearman, Matthew S
Published in Journal of medicinal chemistry (12.06.2014)
Published in Journal of medicinal chemistry (12.06.2014)
Get full text
Journal Article
Advances in the design of new types of inhaled medicines
Czechtizky, Werngard, Su, Wu, Ripa, Lena, Schiesser, Stefan, Höijer, Andreas, Cox, Rhona J
Published in Progress in medicinal chemistry (01.01.2022)
Published in Progress in medicinal chemistry (01.01.2022)
Get full text
Journal Article
Discovery and evaluation of a novel monocyclic series of CXCR2 antagonists
Austin, Rupert P., Bennion, Colin, Bonnert, Roger V., Cheema, Lal, Cook, Anthony R., Cox, Rhona J., Ebden, Mark R., Gaw, Alasdair, Grime, Ken, Meghani, Premji, Nicholls, David, Phillips, Caroline, Smith, Neal, Steele, John, Stonehouse, Jeffrey P.
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Get full text
Journal Article
The First Synthesis of the ABC-Ring System of ‘Upenamide
Schmidt, Jan Peter, Beltrán-Rodil, Sandra, Cox, Rhona J, McAllister, Graeme D, Reid, Mark, Taylor, Richard J. K
Published in Organic letters (27.09.2007)
Published in Organic letters (27.09.2007)
Get full text
Journal Article
Shedding light on the dark genome: drugging long non-coding RNA
Schiesser, Stefan, Czechtizky, Werngard, Cox, Rhona J
Published in Future drug discovery (01.06.2022)
Published in Future drug discovery (01.06.2022)
Get full text
Journal Article
Reinvestigation of the dimerisation process forming isoglaucanic acid
Baldwin, Jack E, Beyeler, Andreas, Cox, Rhona J, Keats, Clare, Pritchard, Gareth J, Adlington, Robert M, Watkin, David J
Published in Tetrahedron (04.06.1999)
Published in Tetrahedron (04.06.1999)
Get full text
Journal Article
Towards a biomimetic synthesis of the marine alkaloids papuamine and haliclonadiamine: Model studies
Adlington, RM, Baldwin, JE, Challis, GL, Cox, RJ, Pritchard, GJ
Published in Tetrahedron (21.01.2000)
Published in Tetrahedron (21.01.2000)
Get full text
Journal Article
Cepaea nemoralis (L.) in Göteborg, S.W. Sweden: variation in a recent urban invader
Cameron, Robert A. D., Cox, Rhona J., Von Proschwitz, Ted, Horsák, Michal
Published in Folia malacologica (07.08.2014)
Published in Folia malacologica (07.08.2014)
Get full text
Journal Article