Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Nav1.7
Minett, Michael S., Pereira, Vanessa, Sikandar, Shafaq, Matsuyama, Ayako, Lolignier, Stéphane, Kanellopoulos, Alexandros H., Mancini, Flavia, Iannetti, Gian D., Bogdanov, Yury D., Santana-Varela, Sonia, Millet, Queensta, Baskozos, Giorgios, MacAllister, Raymond, Cox, James J., Zhao, Jing, Wood, John N.
Published in Nature communications (04.12.2015)
Published in Nature communications (04.12.2015)
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An SCN9A channelopathy causes congenital inability to experience pain
Reimann, Frank, McHale, Duncan P, Valente, Enza Maria, Jafri, Hussain, Al-Gazali, Lihadh, Gribble, Fiona M, Thornton, Gemma, Gorman, Shaun, Williams, Richard, Wood, John N, Nicholas, Adeline K, Roberts, Emma, Mannan, Jovaria, Springell, Kelly, Woods, C. Geoffrey, Cox, James J, Raashid, Yasmin, Karbani, Gulshan, Hamamy, Henan
Published in Nature (14.12.2006)
Published in Nature (14.12.2006)
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The Essential Role of Centrosomal NDE1 in Human Cerebral Cortex Neurogenesis
Bakircioglu, Mehmet, Carvalho, Ofélia P., Khurshid, Maryam, Cox, James J., Tuysuz, Beyhan, Barak, Tanyeri, Yilmaz, Saliha, Caglayan, Okay, Dincer, Alp, Nicholas, Adeline K., Quarrell, Oliver, Springell, Kelly, Karbani, Gulshan, Malik, Saghira, Gannon, Caroline, Sheridan, Eamonn, Crosier, Moira, Lisgo, Steve N., Lindsay, Susan, Bilguvar, Kaya, Gergely, Fanni, Gunel, Murat, Woods, C. Geoffrey
Published in American journal of human genetics (13.05.2011)
Published in American journal of human genetics (13.05.2011)
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Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes
Bangash, M. Ali, Cubuk, Cankut, Iseppon, Federico, Haroun, Rayan, Garcia, Chloe, Luiz, Ana P., Arcangeletti, Manuel, Gossage, Samuel J., Santana-Varela, Sonia, Cox, James J., Lewis, Myles J., Wood, John N., Zhao, Jing
Published in Cell reports (Cambridge) (27.08.2024)
Published in Cell reports (Cambridge) (27.08.2024)
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Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (BDNF) Gene
GRAY, Juliette, YEO, Giles S. H, HODGES, John R, RAYMOND, F. Lucy, O'RAHILLY, Stephen, SADAF FAROOQI, I, COX, James J, MORTON, Jenny, ADLAM, Anna-Lynne R, KEOGH, Julia M, YANOVSKI, Jack A, EL GHARBAWY, Areeg, HAN, Joan C, LORAINE TUNG, Y. C
Published in Diabetes (New York, N.Y.) (01.12.2006)
Published in Diabetes (New York, N.Y.) (01.12.2006)
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TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells
Quick, Kathryn, Zhao, Jing, Eijkelkamp, Niels, Linley, John E., Rugiero, Francois, Cox, James J., Raouf, Ramin, Gringhuis, Martine, Sexton, Jane E., Abramowitz, Joel, Taylor, Ruth, Forge, Andy, Ashmore, Jonathan, Kirkwood, Nerissa, Kros, Corné J., Richardson, Guy P., Freichel, Marc, Flockerzi, Veit, Birnbaumer, Lutz, Wood, John N.
Published in Open biology (01.05.2012)
Published in Open biology (01.05.2012)
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Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia
Koenig, Jennifer, Werdehausen, Robert, Linley, John E, Habib, Abdella M, Vernon, Jeffrey, Lolignier, Stephane, Eijkelkamp, Niels, Zhao, Jing, Okorokov, Andrei L, Woods, C Geoffrey, Wood, John N, Cox, James J
Published in PloS one (02.06.2015)
Published in PloS one (02.06.2015)
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Sodium channel genes in pain-related disorders: phenotype–genotype associations and recommendations for clinical use
Waxman, Stephen G, Prof, Merkies, Ingemar S J, MD, Gerrits, Monique M, PhD, Dib-Hajj, Sulayman D, PhD, Lauria, Giuseppe, Prof, Cox, James J, PhD, Wood, John N, Prof, Woods, C Geoffrey, Prof, Drenth, Joost P H, Prof, Faber, Catharina G, Prof
Published in Lancet neurology (01.11.2014)
Published in Lancet neurology (01.11.2014)
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The Tarantula Venom Peptide Eo1a Binds to the Domain II S3-S4 Extracellular Loop of Voltage-Gated Sodium Channel NaV1.8 to Enhance Activation
Deuis, Jennifer R., Ragnarsson, Lotten, Robinson, Samuel D., Dekan, Zoltan, Chan, Lerena, Jin, Ai-Hua, Tran, Poanna, McMahon, Kirsten L., Li, Shengnan, Wood, John N., Cox, James J., King, Glenn F., Herzig, Volker, Vetter, Irina
Published in Frontiers in pharmacology (14.01.2022)
Published in Frontiers in pharmacology (14.01.2022)
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Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions
Bangash, M A, Alles, Sascha R A, Santana-Varela, Sonia, Millet, Queensta, Sikandar, Shafaq, de Clauser, Larissa, Ter Heegde, Freija, Habib, Abdella M, Pereira, Vanessa, Sexton, Jane E, Emery, Edward C, Li, Shengnan, Luiz, Ana P, Erdos, Janka, Gossage, Samuel J, Zhao, Jing, Cox, James J, Wood, John N
Published in Wellcome open research (2018)
Published in Wellcome open research (2018)
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Tools for analysis and conditional deletion of subsets of sensory neurons
Santana-Varela, Sonia, Bogdanov, Yury D, Gossage, Samuel J, Okorokov, Andrei L, Li, Shengnan, de Clauser, Larissa, Alves-Simoes, Marta, Sexton, Jane E, Iseppon, Federico, Luiz, Ana P, Zhao, Jing, Wood, John N, Cox, James J
Published in Wellcome open research (2021)
Published in Wellcome open research (2021)
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A SOX9 Duplication and Familial 46,XX Developmental Testicular Disorder
Woods, C. Geoffrey, Cox, James J, Homfray, Tessa, Willatt, Lionel
Published in The New England journal of medicine (06.01.2011)
Published in The New England journal of medicine (06.01.2011)
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Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity
Habib, Abdella M., Okorokov, Andrei L., Hill, Matthew N., Bras, Jose T., Lee, Man-Cheung, Li, Shengnan, Gossage, Samuel J., van Drimmelen, Marie, Morena, Maria, Houlden, Henry, Ramirez, Juan D., Bennett, David L.H., Srivastava, Devjit, Cox, James J.
Published in British journal of anaesthesia : BJA (01.08.2019)
Published in British journal of anaesthesia : BJA (01.08.2019)
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Rare NaV1.7 variants associated with painful diabetic peripheral neuropathy
Blesneac, Iulia, Themistocleous, Andreas C., Fratter, Carl, Conrad, Linus J., Ramirez, Juan D., Cox, James J., Tesfaye, Solomon, Shillo, Pallai R., Rice, Andrew S.C., Tucker, Stephen J., Bennett, David L.H.
Published in Pain (Amsterdam) (01.03.2018)
Published in Pain (Amsterdam) (01.03.2018)
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A central mechanism of analgesia in mice and humans lacking the sodium channel NaV1.7
MacDonald, Donald Iain, Sikandar, Shafaq, Weiss, Jan, Pyrski, Martina, Luiz, Ana P., Millet, Queensta, Emery, Edward C., Mancini, Flavia, Iannetti, Gian D., Alles, Sascha R.A., Arcangeletti, Manuel, Zhao, Jing, Cox, James J., Brownstone, Robert M., Zufall, Frank, Wood, John N.
Published in Neuron (Cambridge, Mass.) (05.05.2021)
Published in Neuron (Cambridge, Mass.) (05.05.2021)
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Mapping protein interactions of sodium channel NaV1.7 using epitope‐tagged gene‐targeted mice
Kanellopoulos, Alexandros H, Koenig, Jennifer, Huang, Honglei, Pyrski, Martina, Millet, Queensta, Lolignier, Stéphane, Morohashi, Toru, Gossage, Samuel J, Jay, Maude, Linley, John E, Baskozos, Georgios, Kessler, Benedikt M, Cox, James J, Dolphin, Annette C, Zufall, Frank, Wood, John N, Zhao, Jing
Published in The EMBO journal (01.02.2018)
Published in The EMBO journal (01.02.2018)
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The Genetics of Pain: Implications for Therapeutics
Sexton, Jane E, Cox, James J, Zhao, Jing, Wood, John N
Published in Annual review of pharmacology and toxicology (06.01.2018)
Published in Annual review of pharmacology and toxicology (06.01.2018)
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Molecular basis of FAAH-OUT-associated human pain insensitivity
Mikaeili, Hajar, Habib, Abdella M, Yeung, Charlix Wai-Lok, Santana-Varela, Sonia, Luiz, Ana P, Panteleeva, Kseniia, Zuberi, Sana, Athanasiou-Fragkouli, Alkyoni, Houlden, Henry, Wood, John N, Okorokov, Andrei L, Cox, James J
Published in Brain (London, England : 1878) (01.09.2023)
Published in Brain (London, England : 1878) (01.09.2023)
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