The Neuroprotective Effect of a Specific P2X7 Receptor Antagonist Derives from its Ability to Inhibit Assembly of the NLRP3 Inflammasome in Glial Cells
Murphy, Niamh, Cowley, Thelma R., Richardson, Jill C., Virley, David, Upton, Neil, Walter, Daryl, Lynch, Marina A.
Published in Brain pathology (Zurich, Switzerland) (01.05.2012)
Published in Brain pathology (Zurich, Switzerland) (01.05.2012)
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The fatty acid amide hydrolase inhibitor URB597 exerts anti-inflammatory effects in hippocampus of aged rats and restores an age-related deficit in long-term potentiation
Murphy, Niamh, Cowley, Thelma R, Blau, Christoph W, Dempsey, Colin N, Noonan, Janis, Gowran, Aoife, Tanveer, Riffat, Olango, Weredeselam M, Finn, David P, Campbell, Veronica A, Lynch, Marina A
Published in Journal of neuroinflammation (26.04.2012)
Published in Journal of neuroinflammation (26.04.2012)
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Journal Article
The age-related deficit in LTP is associated with changes in perfusion and blood-brain barrier permeability
Blau, Christoph W, Cowley, Thelma R, O'Sullivan, Joan, Grehan, Belinda, Browne, Tara C, Kelly, Laura, Birch, Amy, Murphy, Niamh, Kelly, Aine M, Kerskens, Christian M, Lynch, Marina A
Published in Neurobiology of aging (01.05.2012)
Published in Neurobiology of aging (01.05.2012)
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Journal Article
Rosiglitazone attenuates the age-related changes in astrocytosis and the deficit in LTP
Cowley, Thelma R, O'Sullivan, Joan, Blau, Christoph, Deighan, Brian F, Jones, Raasay, Kerskens, Christian, Richardson, Jill C, Virley, David, Upton, Neil, Lynch, Marina A
Published in Neurobiology of aging (2012)
Published in Neurobiology of aging (2012)
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Age-related changes in the hippocampus (loss of synaptophysin and glial–synaptic interaction) are modified by systemic treatment with an NCAM-derived peptide, FGL
Ojo, Bunmi, Rezaie, Payam, Gabbott, Paul L, Davies, Heather, Colyer, Frances, Cowley, Thelma R, Lynch, Marina, Stewart, Michael G
Published in Brain, behavior, and immunity (01.07.2012)
Published in Brain, behavior, and immunity (01.07.2012)
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Journal Article
A novel anti-inflammatory role of NCAM-derived mimetic peptide, FGL
Downer, Eric J, Cowley, Thelma R, Lyons, Anthony, Mills, Kingston H.G, Berezin, Vladimir, Bock, Elisabeth, Lynch, Marina A
Published in Neurobiology of aging (01.01.2010)
Published in Neurobiology of aging (01.01.2010)
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Journal Article
The impact of glial activation in the aging brain
Lynch, Aileen M, Murphy, Kevin J, Deighan, Brian F, O'Reilly, Julie-Ann, Gun'ko, Yuri K, Cowley, Thelma R, Gonzalez-Reyes, Rodrigo E, Lynch, Marina A
Published in Aging and disease (01.12.2010)
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Published in Aging and disease (01.12.2010)
Journal Article
synthetic NCAM-derived mimetic peptide, FGL, exerts anti-inflammatory properties via IGF-1 and interferon-γ modulation
Downer, Eric J, Cowley, Thelma R, Cox, Fionnuala, Maher, Francis O, Berezin, Vladimir, Bock, Elisabeth, Lynch, Marina A
Published in Journal of neurochemistry (01.06.2009)
Published in Journal of neurochemistry (01.06.2009)
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Journal Article
An NCAM Mimetic, FGL, Alters Hippocampal Cellular Morphometry in Young Adult (4 Month-Old) Rats
Ojo, Bunmi, Gabbott, Paul L., Rezaie, Payam, Corbett, Nicola, Medvedev, Nikolay I., Cowley, Thelma R., Lynch, Marina A., Stewart, Michael G.
Published in Neurochemical research (01.06.2013)
Published in Neurochemical research (01.06.2013)
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A cell adhesion molecule mimetic, FGL peptide, induces alterations in synapse and dendritic spine structure in the dentate gyrus of aged rats: a three-dimensional ultrastructural study
Popov, Victor I., Medvedev, Nikolay I., Kraev, Igor V., Gabbott, Paul L., Davies, Heather A., Lynch, Marina, Cowley, Thelma R., Berezin, Vladimir, Bock, Elisabeth, Stewart, Michael G.
Published in The European journal of neuroscience (01.01.2008)
Published in The European journal of neuroscience (01.01.2008)
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The effect of the PPAR gamma agonist rosiglitazone on age-related changes in grey matter magnetic resonance relaxometry in the rat
Blau, Christoph W, Cowley, Thelma R, O'Sullivan, Joan B, Jones, Raasay S, Kerskens, Christian M, Lynch, Marina A
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article
The effect of the PPAR gamma agonist rosiglitazone on age-related changes in grey matter magnetic resonance relaxometry in the rat
Blau, Christoph W, Cowley, Thelma R, O'Sullivan, Joan B, Jones, Raasay S, Kerskens, Christian M, Lynch, Marina A
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article
The Neuroprotective Effect of a Specific P2X 7 Receptor Antagonist Derives from its Ability to Inhibit Assembly of the NLRP3 Inflammasome in Glial Cells
Murphy, Niamh, Cowley, Thelma R., Richardson, Jill C., Virley, David, Upton, Neil, Walter, Daryl, Lynch, Marina A.
Published in Brain pathology (Zurich, Switzerland) (01.05.2012)
Published in Brain pathology (Zurich, Switzerland) (01.05.2012)
Get full text
Journal Article
A synthetic NCAM-derived mimetic peptide, FGL, exerts anti-inflammatory properties via IGF-1 and interferon-[gamma] modulation
Downer, Eric J, Cowley, Thelma R, Cox, Fionnuala, Maher, Francis O, Berezin, Vladimir, Bock, Elisabeth, Lynch, Marina A
Published in Journal of neurochemistry (01.06.2009)
Published in Journal of neurochemistry (01.06.2009)
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Journal Article
IC‐P‐005: The effect of the PPAR gamma agonist rosiglitazone on age‐related changes in grey matter magnetic resonance relaxometry in the rat
Blau, Christoph W., Cowley, Thelma R., O'Sullivan, Joan B., Jones, Raasay S., Kerskens, Christian M., Lynch, Marina A.
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article