Total Synthesis of Bryostatin 1
Keck, Gary E, Poudel, Yam B, Cummins, Thomas J, Rudra, Arnab, Covel, Jonathan A
Published in Journal of the American Chemical Society (02.02.2011)
Published in Journal of the American Chemical Society (02.02.2011)
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Synthesis of analogs of the Gwt1 inhibitor manogepix (APX001A) and in vitro evaluation against Cryptococcus spp
Trzoss, Michael, Covel, Jonathan A., Kapoor, Mili, Moloney, Molly K., Soltow, Quinlyn A., Webb, Peter J., Shaw, Karen Joy
Published in Bioorganic & medicinal chemistry letters (01.12.2019)
Published in Bioorganic & medicinal chemistry letters (01.12.2019)
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Journal Article
A calcineurin antifungal strategy with analogs of FK506
Nambu, Mitchell, Covel, Jonathan A., Kapoor, Mili, Li, Xiaoming, Moloney, Molly K., Numa, Mehdi M., Soltow, Quinlyn A., Trzoss, Michael, Webb, Peter, Webb, Robert R., Mutz, Mitchell
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
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A new family of H3 receptor antagonists based on the natural product Conessine
SANTORA, Vincent J, COVEL, Jonathan A, WEBB, Robert R, SAGE, Carleton, REN, Albert, PEREIRA, Guilherme, KNUDSEN, Jens, EDWARDS, Jeffrey E, SUAREZ, Marissa, FRAZER, John, THOMSEN, William, HAUSER, Erin, HAYASHI, Rena, WHELAN, Kevin, GROTTICK, Andrew J, HOFILENA, Brian J, IBARRA, Jason B, PULLEY, Michelle D, WEINHOUSE, Michael I, SENGUPTA, Dipanjan, DUFFIELD, Jonathan J, SEMPLE, Graeme
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
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Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4′-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl)-2-methylpyrrolidine (APD916)
Semple, Graeme, Santora, Vincent J., Smith, Jeffrey M., Covel, Jonathan A., Hayashi, Rena, Gallardo, Charlemagne, Ibarra, Jason B., Schultz, Jeffrey A., Park, Douglas M., Estrada, Scott A., Hofilena, Brian J., Smith, Brian M., Ren, Albert, Suarez, Marissa, Frazer, John, Edwards, Jeffrey E., Hart, Ryan, Hauser, Erin K., Lorea, Jodie, Grottick, Andrew J.
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
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Journal Article
Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H3 Receptor Inverse Agonist Activity
Covel, Jonathan A., Santora, Vincent J., Smith, Jeffrey M., Hayashi, Rena, Gallardo, Charlemagne, Weinhouse, Michael I., Ibarra, Jason B., Schultz, Jeffrey A., Park, Douglas M., Estrada, Scott A., Hofilena, Brian J., Pulley, Michelle D., Smith, Brian M., Ren, Albert, Suarez, Marissa, Frazer, John, Edwards, Jeffrey, Hauser, Erin K., Lorea, Jodie, Semple, Graeme, Grottick, Andrew J.
Published in Journal of medicinal chemistry (24.09.2009)
Published in Journal of medicinal chemistry (24.09.2009)
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Journal Article
Design and Evaluation of Novel Biphenyl Sulfonamide Derivatives with Potent Histamine H(3) Receptor Inverse Agonist Activity
Covel, Jonathan A., Santora, Vincent J., Smith, Jeffrey M., Hayashi, Rena, Gallardo, Charlemagne, Weinhouse, Michael I., Ibarra, Jason B., Schultz, Jeffrey A., Park, Douglas M., Estrada, Scott A., Hofilena, Brian J., Pulley, Michelle D., Smith, Brian M., Ren, Albert, Suarez, Marissa, Frazer, John, Edwards, Jeffrey, Hauser, Erin K., Lorca, Jodie, Semple, Graeme, Grottick, Andrew J.
Published in Journal of medicinal chemistry (24.09.2009)
Published in Journal of medicinal chemistry (24.09.2009)
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Journal Article
Novel H3 receptor antagonists with improved pharmacokinetic profiles
SANTORA, Vincent J, COVEL, Jonathan A, EDWARDS, Jeffrey E, SUAREZ, Marissa, FRAZER, John, THOMSEN, William, HAUSER, Erin, LOREA, Jodie, GROTTICK, Andrew J, HAYASHI, Rena, HOFILENA, Brian J, IBARRA, Jason B, PULLEY, Michelle D, WEINHOUSE, Michael I, SEMPLE, Graeme, REN, Albert, PEREIRA, Guilherme
Published in Bioorganic & medicinal chemistry letters (15.07.2008)
Published in Bioorganic & medicinal chemistry letters (15.07.2008)
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Journal Article
Asymmetric Total Synthesis of Rhizoxin D
Keck, Gary E., Wager, Carrie A., Wager, Travis T., Savin, Kenneth A., Covel, Jonathan A., McLaws, Mark D., Krishnamurthy, Dhileep, Cee, Victor J.
Published in Angewandte Chemie (International ed.) (05.01.2001)
Published in Angewandte Chemie (International ed.) (05.01.2001)
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Journal Article
APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia
Viriyakosol, Suganya, Kapoor, Mili, Okamoto, Sharon, Covel, Jonathan, Soltow, Quinlyn A, Trzoss, Michael, Shaw, Karen Joy, Fierer, Joshua
Published in Antimicrobial agents and chemotherapy (01.02.2019)
Published in Antimicrobial agents and chemotherapy (01.02.2019)
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Journal Article
In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus
Shaw, Karen Joy, Schell, Wiley A, Covel, Jonathan, Duboc, Gisele, Giamberardino, C, Kapoor, Mili, Moloney, Molly, Soltow, Quinlyn A, Tenor, Jennifer L, Toffaletti, Dena L, Trzoss, Michael, Webb, Peter, Perfect, John R
Published in Antimicrobial agents and chemotherapy (01.08.2018)
Published in Antimicrobial agents and chemotherapy (01.08.2018)
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Synthesis of ansa-Titanocenes from 1,2-Bis(2-indenyl)ethane and Structural Comparisons in the Catalytic Epoxidation of Unfunctionalized Alkenes
Hitchcock, Shawn R, Situ, Janelle J, Covel, Jonathan A, Olmstead, Marilyn M, Nantz, Michael H
Published in Organometallics (01.08.1995)
Published in Organometallics (01.08.1995)
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Journal Article
Asymmetric Total Synthesis of Rhizoxin D Financial support has been provided by the National Institutes of Health (through grant GM-28961) and by Pfizer, Inc
Keck, Gary E., Wager, Carrie A., Wager, Travis T., Savin, Kenneth A., Covel, Jonathan A., McLaws, Mark D., Krishnamurthy, Dhileep, Cee, Victor J.
Published in Angewandte Chemie International Edition (05.01.2001)
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Published in Angewandte Chemie International Edition (05.01.2001)
Journal Article
A new family of H 3 receptor antagonists based on the natural product Conessine
Santora, Vincent J., Covel, Jonathan A., Hayashi, Rena, Hofilena, Brian J., Ibarra, Jason B., Pulley, Michelle D., Weinhouse, Michael I., Sengupta, Dipanjan, Duffield, Jonathan J., Semple, Graeme, Webb, Robert R., Sage, Carleton, Ren, Albert, Pereira, Guilherme, Knudsen, Jens, Edwards, Jeffrey E., Suarez, Marissa, Frazer, John, Thomsen, William, Hauser, Erin, Whelan, Kevin, Grottick, Andrew J.
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
Published in Bioorganic & medicinal chemistry letters (15.02.2008)
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Journal Article
Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-2-(4'-(3-methoxypropylsulfonyl)biphenyl-4-yl)ethyl-2-methylpyrrolidine (APD916)
SEMPLE, Graeme, SANTORA, Vincent J, HOFILENA, Brian J, SMITH, Brian M, REN, Albert, SUAREZ, Marissa, FRAZER, John, EDWARDS, Jeffrey E, HART, Ryan, HAUSER, Erin K, LOREA, Jodie, GROTTICK, Andrew J, SMITH, Jeffrey M, COVEL, Jonathan A, HAYASHI, Rena, GALLARDO, Charlemagne, IBARRA, Jason B, SCHULTZ, Jeffrey A, PARK, Douglas M, ESTRADA, Scott A
Published in Bioorganic & medicinal chemistry letters (2012)
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Published in Bioorganic & medicinal chemistry letters (2012)
Journal Article
Identification of biaryl sulfone derivatives as antagonists of the histamine H3 receptor: Discovery of (R)-1-(2-(4&; prime; -(3-methoxypropylsulfonyl)biphenyl-4-yl)e thyl)-2-methylpyrrolidine (APD916)
Semple, Graeme, Santora, Vincent J, Smith, Jeffrey M, Covel, Jonathan A, Hayashi, Rena, Gallardo, Charlemagne, Ibarra, Jason B, Schultz, Jeffrey A, Park, Douglas M, Estrada, Scott A, Hofilena, Brian J, Smith, Brian M, Ren, Albert, Suarez, Marissa, Frazer, John, Edwards, Jeffrey E, Hart, Ryan, Hauser, Erin K, Lorea, Jodie, Grottick, Andrew J
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
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