The PI3K Pathway As Drug Target in Human Cancer
COURTNEY, Kevin D, CORCORAN, Ryan B, ENGELMAN, Jeffrey A
Published in Journal of clinical oncology (20.02.2010)
Published in Journal of clinical oncology (20.02.2010)
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Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma
Davidson, Shawn M, Schmidt, Daniel R, Heyman, Julia E, O'Brien, James P, Liu, Amy C, Israelsen, William J, Dayton, Talya L, Sehgal, Raghav, Bronson, Roderick T, Freinkman, Elizaveta, Mak, Howard H, Fanelli, Giuseppe Nicolò, Malstrom, Scott, Bellinger, Gary, Carracedo, Arkaitz, Pandolfi, Pier Paolo, Courtney, Kevin D, Jha, Abhishek, DePinho, Ronald A, Horner, James W, Thomas, Craig J, Cantley, Lewis C, Loda, Massimo, Vander Heiden, Matthew G
Published in Cancer research (Chicago, Ill.) (05.07.2022)
Published in Cancer research (Chicago, Ill.) (05.07.2022)
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Phase II trial of RAD001 and bicalutamide for castration‐resistant prostate cancer
Nakabayashi, Mari, Werner, Lilian, Courtney, Kevin D., Buckle, Geoffrey, Oh, William K., Bubley, Glen J., Hayes, Julia H., Weckstein, Douglas, Elfiky, Aymen, Sims, Danny M., Kantoff, Philip W., Taplin, Mary‐Ellen
Published in BJU international (01.12.2012)
Published in BJU international (01.12.2012)
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Journal Article
Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma
Courtney, Kevin D, Infante, Jeffrey R, Lam, Elaine T, Figlin, Robert A, Rini, Brian I, Brugarolas, James, Zojwalla, Naseem J, Lowe, Ann M, Wang, Keshi, Wallace, Eli M, Josey, John A, Choueiri, Toni K
Published in Journal of clinical oncology (20.03.2018)
Published in Journal of clinical oncology (20.03.2018)
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Journal Article
Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo
Courtney, Kevin D., Bezwada, Divya, Mashimo, Tomoyuki, Pichumani, Kumar, Vemireddy, Vamsidhara, Funk, Alexander M., Wimberly, Jennifer, McNeil, Sarah S., Kapur, Payal, Lotan, Yair, Margulis, Vitaly, Cadeddu, Jeffrey A., Pedrosa, Ivan, DeBerardinis, Ralph J., Malloy, Craig R., Bachoo, Robert M., Maher, Elizabeth A.
Published in Cell metabolism (06.11.2018)
Published in Cell metabolism (06.11.2018)
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Journal Article
HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma
Courtney, Kevin D, Ma, Yuanqing, Diaz de Leon, Alberto, Christie, Alana, Xie, Zhiqun, Woolford, Layton, Singla, Nirmish, Joyce, Allison, Hill, Haley, Madhuranthakam, Ananth J, Yuan, Qing, Xi, Yin, Zhang, Yue, Chang, Jenny, Fatunde, Oluwatomilade, Arriaga, Yull, Frankel, Arthur E, Kalva, Sanjeeva, Zhang, Song, McKenzie, Tiffani, Reig Torras, Oscar, Figlin, Robert A, Rini, Brian I, McKay, Renée M, Kapur, Payal, Wang, Tao, Pedrosa, Ivan, Brugarolas, James
Published in Clinical cancer research (15.02.2020)
Published in Clinical cancer research (15.02.2020)
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The role of the radiologist in the prostate cancer multidisciplinary conference
Costa, Daniel N., Nguyen, Nghi, Garant, Aurelie, Meng, Xiaosong, Courtney, Kevin D., Shah, Rajal B., Pedrosa, Ivan
Published in Abdominal imaging (01.07.2024)
Published in Abdominal imaging (01.07.2024)
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Journal Article
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
Anastasiou, Dimitrios, Yu, Yimin, Israelsen, William J, Jiang, Jian-Kang, Boxer, Matthew B, Hong, Bum Soo, Tempel, Wolfram, Dimov, Svetoslav, Shen, Min, Jha, Abhishek, Yang, Hua, Mattaini, Katherine R, Metallo, Christian M, Fiske, Brian P, Courtney, Kevin D, Malstrom, Scott, Khan, Tahsin M, Kung, Charles, Skoumbourdis, Amanda P, Veith, Henrike, Southall, Noel, Walsh, Martin J, Brimacombe, Kyle R, Leister, William, Lunt, Sophia Y, Johnson, Zachary R, Yen, Katharine E, Kunii, Kaiko, Davidson, Shawn M, Christofk, Heather R, Austin, Christopher P, Inglese, James, Harris, Marian H, Asara, John M, Stephanopoulos, Gregory, Salituro, Francesco G, Jin, Shengfang, Dang, Lenny, Auld, Douglas S, Park, Hee-Won, Cantley, Lewis C, Thomas, Craig J, Vander Heiden, Matthew G
Published in Nature chemical biology (01.10.2012)
Published in Nature chemical biology (01.10.2012)
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Journal Article
Review: Updates on novel therapies for metastatic renal cell carcinoma
Courtney, Kevin D., Choueiri, Toni K.
Published in Therapeutic Advances in Medical Oncology (01.05.2010)
Published in Therapeutic Advances in Medical Oncology (01.05.2010)
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Book Review
Journal Article
Mitochondrial complex I promotes kidney cancer metastasis
Bezwada, Divya, Perelli, Luigi, Lesner, Nicholas P., Cai, Ling, Brooks, Bailey, Wu, Zheng, Vu, Hieu S., Sondhi, Varun, Cassidy, Daniel L., Kasitinon, Stacy, Kelekar, Sherwin, Cai, Feng, Aurora, Arin B., Patrick, McKenzie, Leach, Ashley, Ghandour, Rashed, Zhang, Yuanyuan, Do, Duyen, McDaniel, Phyllis, Sudderth, Jessica, Dumesnil, Dennis, House, Sara, Rosales, Tracy, Poole, Alan M., Lotan, Yair, Woldu, Solomon, Bagrodia, Aditya, Meng, Xiaosong, Cadeddu, Jeffrey A., Mishra, Prashant, Garcia-Bermudez, Javier, Pedrosa, Ivan, Kapur, Payal, Courtney, Kevin D., Malloy, Craig R., Genovese, Giannicola, Margulis, Vitaly, DeBerardinis, Ralph J.
Published in Nature (London) (26.09.2024)
Published in Nature (London) (26.09.2024)
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Journal Article
MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG
Fets, Louise, Driscoll, Paul C., Grimm, Fiona, Jain, Aakriti, Nunes, Patrícia M., Gounis, Michalis, Doglioni, Ginevra, Papageorgiou, George, Ragan, Timothy J., Campos, Sebastien, Silva dos Santos, Mariana, MacRae, James I., O’Reilly, Nicola, Wright, Alan J., Benes, Cyril H., Courtney, Kevin D., House, David, Anastasiou, Dimitrios
Published in Nature chemical biology (01.11.2018)
Published in Nature chemical biology (01.11.2018)
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Journal Article
Author Correction: MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG
Fets, Louise, Driscoll, Paul C., Grimm, Fiona, Jain, Aakriti, Nunes, Patrícia M., Gounis, Michalis, Doglioni, Ginevra, Papageorgiou, George, Ragan, Timothy J., Campos, Sebastien, dos Santos, Mariana Silva, MacRae, James I., O’Reilly, Nicola, Wright, Alan J., Benes, Cyril H., Courtney, Kevin D., House, David, Anastasiou, Dimitrios
Published in Nature chemical biology (01.12.2019)
Published in Nature chemical biology (01.12.2019)
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Journal Article
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
Anastasiou, Dimitrios, Yu, Yimin, Israelsen, William J, Jiang, Jian-Kang, Boxer, Matthew B, Hong, Bum Soo, Tempel, Wolfram, Dimov, Svetoslav, Shen, Min, Jha, Abhishek, Yang, Hua, Mattaini, Katherine R, Metallo, Christian M, Fiske, Brian P, Courtney, Kevin D, Malstrom, Scott, Khan, Tahsin M, Kung, Charles, Skoumbourdis, Amanda P, Veith, Henrike, Southall, Noel, Walsh, Martin J, Brimacombe, Kyle R, Leister, William, Lunt, Sophia Y, Johnson, Zachary R, Yen, Katharine E, Kunii, Kaiko, Davidson, Shawn M, Christofk, Heather R, Austin, Christopher P, Inglese, James, Harris, Marian H, Asara, John M, Stephanopoulos, Gregory, Salituro, Francesco G, Jin, Shengfang, Dang, Lenny, Auld, Douglas S, Park, Hee-Won, Cantley, Lewis C, Thomas, Craig J, Vander Heiden, Matthew G
Published in Nature chemical biology (26.08.2012)
Published in Nature chemical biology (26.08.2012)
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Journal Article
A Phase I Study of Everolimus and Docetaxel in Patients With Castration-Resistant Prostate Cancer
Courtney, Kevin D, Manola, Judith B, Elfiky, Aymen A, Ross, Robert, Oh, William K, Yap, Jeffrey T, Van den Abbeele, Annick D, Ryan, Christopher W, Beer, Tomasz M, Loda, Massimo, Priolo, Carmen, Kantoff, Philip, Taplin, Mary-Ellen
Published in Clinical genitourinary cancer (01.04.2015)
Published in Clinical genitourinary cancer (01.04.2015)
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Journal Article
PI3K Enters Beta-Testing
Shaywitz, Adam J., Courtney, Kevin D., Patnaik, Akash, Cantley, Lewis C.
Published in Cell metabolism (01.09.2008)
Published in Cell metabolism (01.09.2008)
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