Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation
Vinci, Maria, Gowan, Sharon, Boxall, Frances, Patterson, Lisa, Zimmermann, Miriam, Court, William, Lomas, Cara, Mendiola, Marta, Hardisson, David, Eccles, Suzanne A
Published in BMC biology (22.03.2012)
Published in BMC biology (22.03.2012)
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Journal Article
Breast Tumour Kinase (Brk/PTK6) Contributes to Breast Tumour Xenograft Growth and Modulates Chemotherapeutic Responses In Vitro
Burmi, Rajpal S, Box, Gary M, Wazir, Umar, Hussain, Haroon A, Davies, Julie A, Court, William J, Eccles, Suzanne A, Jiang, Wen G, Mokbel, Kefah, Harvey, Amanda J
Published in Genes (24.02.2022)
Published in Genes (24.02.2022)
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Journal Article
Brk Protects Breast Cancer Cells from Autophagic Cell Death Induced by Loss of Anchorage
Harvey, Amanda J, Pennington, Caroline J, Porter, Sarah, Burmi, Rajpal S, Edwards, Dylan R, Court, William, Eccles, Suzanne A, Crompton, Mark R
Published in The American journal of pathology (01.09.2009)
Published in The American journal of pathology (01.09.2009)
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Journal Article
Syk tyrosine kinase is linked to cell motility and progression in squamous cell carcinomas of the head and neck
LUANGDILOK, Sutima, BOX, Carol, PATTERSON, Lisa, COURT, William, HARRINGTON, Kevin, PITKIN, Lisa, RHYS-EVANS, Peter, O-CHAROENRAT, Pornchai, ECCLES, Suzanne
Published in Cancer research (Chicago, Ill.) (15.08.2007)
Published in Cancer research (Chicago, Ill.) (15.08.2007)
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Journal Article
In vitro assays for endothelial cell functions related to angiogenesis: proliferation, motility, tubular differentiation, and proteolysis
Eccles, Suzanne A, Court, William, Patterson, Lisa, Sanderson, Sharon
Published in Methods in molecular biology (Clifton, N.J.) (2009)
Published in Methods in molecular biology (Clifton, N.J.) (2009)
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Journal Article
Epidermal growth factor-like ligands differentially up-regulate matrix metalloproteinase 9 in head and neck squamous carcinoma cells
O-CHAROENRAT, P, MODJTAHEDI, H, RHYS-EVANS, P, COURT, W. J, BOX, G. M, ECCLES, S. A
Published in Cancer research (Chicago, Ill.) (15.02.2000)
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Published in Cancer research (Chicago, Ill.) (15.02.2000)
Journal Article
Differential modulation of proliferation, matrix metalloproteinase expression and invasion of human head and neck squamous carcinoma cells by c-erbB ligands
O-charoenrat, P, Rhys-Evans, P, Court, W J, Box, G M, Eccles, S A
Published in Clinical & experimental metastasis (01.01.1999)
Published in Clinical & experimental metastasis (01.01.1999)
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Journal Article
A Cyclic Peptide Inhibitor of HIF‑1 Heterodimerization That Inhibits Hypoxia Signaling in Cancer Cells
Miranda, Elena, Nordgren, Ida K, Male, Abigail L, Lawrence, Charlotte E, Hoakwie, Franciane, Cuda, Francesco, Court, William, Fox, Keith R, Townsend, Paul A, Packham, Graham K, Eccles, Suzanne A, Tavassoli, Ali
Published in Journal of the American Chemical Society (17.07.2013)
Published in Journal of the American Chemical Society (17.07.2013)
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Journal Article
PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion
Dart, Anna E, Box, Gary M, Court, William, Gale, Madeline E, Brown, John P, Pinder, Sarah E, Eccles, Suzanne A, Wells, Claire M
Published in The Journal of cell biology (23.11.2015)
Published in The Journal of cell biology (23.11.2015)
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Journal Article
Identification of ovarian high-grade serous carcinoma cell lines that show estrogen-sensitive growth as xenografts in immunocompromised mice
De Haven Brandon, Alexis, Box, Gary, Hallsworth, Albert, Court, William, Matthews, Nicoll, Herodek, Balint, Arteagabeitia, Aitor Bermejo, Valenti, Melanie, Kirkin, Vladimir
Published in Scientific reports (01.07.2020)
Published in Scientific reports (01.07.2020)
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Journal Article
Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen
Mallinger, Aurélie, Crumpler, Simon, Pichowicz, Mark, Waalboer, Dennis, Stubbs, Mark, Adeniji-Popoola, Olajumoke, Wood, Bozena, Smith, Elizabeth, Thai, Ching, Henley, Alan T, Georgi, Katrin, Court, William, Hobbs, Steve, Box, Gary, Ortiz-Ruiz, Maria-Jesus, Valenti, Melanie, De Haven Brandon, Alexis, TePoele, Robert, Leuthner, Birgitta, Workman, Paul, Aherne, Wynne, Poeschke, Oliver, Dale, Trevor, Wienke, Dirk, Esdar, Christina, Rohdich, Felix, Raynaud, Florence, Clarke, Paul A, Eccles, Suzanne A, Stieber, Frank, Schiemann, Kai, Blagg, Julian
Published in Journal of medicinal chemistry (26.02.2015)
Published in Journal of medicinal chemistry (26.02.2015)
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Journal Article
The identification of novel PLC-γ inhibitors using virtual high throughput screening
Reynisson, Jóhannes, Court, William, O’Neill, Ciaran, Day, James, Patterson, Lisa, McDonald, Edward, Workman, Paul, Katan, Matilda, Eccles, Suzanne A.
Published in Bioorganic & medicinal chemistry (15.04.2009)
Published in Bioorganic & medicinal chemistry (15.04.2009)
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Journal Article
Abstract 463: MAP4K4 (HGK) plays a key role in tumor progression
Hedayat, Somaieh, Vinci, Mara, Lomas, Cara, Court, William, Eccles, Suzanne A.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Reversed-phase high-performance liquid chromatography determination of ginsenosides of Panax quinquefolium
Court, William A., Hendel, John G., Elmi, Jama
Published in Journal of Chromatography A (01.11.1996)
Published in Journal of Chromatography A (01.11.1996)
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Journal Article
Cell migration/invasion assays and their application in cancer drug discovery
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Book Chapter
Journal Article
Overexpression of epidermal growth factor receptor in human head and neck squamous carcinoma cell lines correlates with matrix metalloproteinase‐9 expression and in vitro invasion
O‐Charoenrat, Pornchai, Rhys‐Evans, Peter, Modjtahedi, Helmout, Court, William, Box, Gary, Eccles, Suzanne
Published in International journal of cancer (01.05.2000)
Published in International journal of cancer (01.05.2000)
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Journal Article