Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study
Nicoletti, Paola, Aithal, Guruprasad P, Bjornsson, Einar S, Andrade, Raul J, Sawle, Ashley, Arrese, Marco, Barnhart, Huiman X, Bondon-Guitton, Emmanuelle, Hayashi, Paul H, Bessone, Fernando, Carvajal, Alfonso, Cascorbi, Ingolf, Cirulli, Elizabeth T, Chalasani, Naga, Conforti, Anita, Coulthard, Sally A, Daly, Mark J, Day, Christopher P, Dillon, John F, Fontana, Robert J, Grove, Jane I, Hallberg, Pär, Hernández, Nelia, Ibáñez, Luisa, Kullak-Ublick, Gerd A, Laitinen, Tarja, Larrey, Dominique, Lucena, M. Isabel, Maitland-van der Zee, Anke H, Martin, Jennifer H, Molokhia, Mariam, Pirmohamed, Munir, Powell, Elizabeth E, Qin, Shengying, Serrano, Jose, Stephens, Camilla, Stolz, Andrew, Wadelius, Mia, Watkins, Paul B, Floratos, Aris, Shen, Yufeng, Nelson, Matthew R, Urban, Thomas J, Daly, Ann K
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2017)
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HLA-DRB116: 01-DQB105: 02 is a novel genetic risk factor for flupirtine-induced liver injury
Nicoletti, Paola, Werk, Anneke N, Sawle, Ashley, Shen, Yufeng, Urban, Thomas J, Coulthard, Sally A, Bjornsson, Einar S, Cascorbi, Ingolf, Floratos, Aris, Stammschulte, Thomas, Gundert-Remy, Ursula, Nelson, Matthew R, Aithal, Guruprasad P, Daly, Ann K
Published in Pharmacogenetics and genomics (01.05.2016)
Published in Pharmacogenetics and genomics (01.05.2016)
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Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles
Nicoletti, Paola, Aithal, Guruprasad P, Chamberlain, Thomas C, Coulthard, Sally, Alshabeeb, Mohammad, Grove, Jane I, Andrade, Raul J, Bjornsson, Einar, Dillon, John F, Hallberg, Par, Lucena, M Isabel, Maitland-van der Zee, Anke H, Martin, Jennifer H, Molokhia, Mariam, Pirmohamed, Munir, Wadelius, Mia, Shen, Yufeng, Nelson, Matthew R, Daly, Ann K
Published in Clinical pharmacology and therapeutics (01.07.2019)
Published in Clinical pharmacology and therapeutics (01.07.2019)
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Increased DNA-incorporated thiopurine metabolite as a possible mechanism for leukocytopenia through cell apoptosis in inflammatory bowel disease patients with NUDT15 mutation
Toyonaga, Takahiko, Kobayashi, Taku, Kuronuma, Satoshi, Ueno, Aito, Kiyohara, Hiroki, Okabayashi, Shinji, Takeuchi, Osamu, Redfern, Christopher P. F., Terai, Hideki, Ozaki, Ryo, Sagami, Shintaro, Nakano, Masaru, Coulthard, Sally A., Tanaka, Yoichi, Hibi, Toshifumi
Published in Journal of gastroenterology (01.11.2021)
Published in Journal of gastroenterology (01.11.2021)
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Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers
Zaremba, Tomasz, Thomas, Huw D, Cole, Michael, Coulthard, Sally A, Plummer, Elizabeth R, Curtin, Nicola J
Published in Biochemical journal (15.06.2011)
Published in Biochemical journal (15.06.2011)
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Liquid chromatography–mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients
Coulthard, Sally A., Berry, Phil, McGarrity, Sarah, Ansari, Azhar, Redfern, Christopher P.F.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.08.2016)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.08.2016)
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Azathioprine with Allopurinol: Lower Deoxythioguanosine in DNA and Transcriptome Changes Indicate Mechanistic Differences to Azathioprine Alone
Coulthard, Sally A, Berry, Phil, McGarrity, Sarah, McLaughlin, Simon, Ansari, Azhar, Redfern, Christopher P F
Published in Inflammatory bowel diseases (01.06.2017)
Published in Inflammatory bowel diseases (01.06.2017)
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Nomenclature for alleles of the thiopurine methyltransferase gene
Appell, Malin L, Berg, Jonathan, Duley, John, Evans, William E, Kennedy, Martin A, Lennard, Lynne, Marinaki, Tony, McLeod, Howard L, Relling, Mary V, Schaeffeler, Elke, Schwab, Matthias, Weinshilboum, Richard, Yeoh, Allen E J, McDonagh, Ellen M, Hebert, Joan M, Klein, Teri E, Coulthard, Sally A
Published in Pharmacogenetics and genomics (01.04.2013)
Published in Pharmacogenetics and genomics (01.04.2013)
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Thiopurines: Factors influencing toxicity and response
Fotoohi, Alan Kambiz, Coulthard, Sally A., Albertioni, Freidoun
Published in Biochemical pharmacology (01.05.2010)
Published in Biochemical pharmacology (01.05.2010)
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Phase I Study of MG98, an Oligonucleotide Antisense Inhibitor of Human DNA Methyltransferase 1, Given as a 7-Day Infusion in Patients with Advanced Solid Tumors
PLUMMER, Ruth, VIDAL, Laura, REID, Gregory K, MCLEOD, A. Robert, BESTERMAN, Jeffrey M, LEE, Chooi, JUDSON, Ian, CALVERT, Hilary, BODDY, Alan V, GRIFFIN, Melanie, LESLEY, Mark, DE BONO, Johann, COULTHARD, Sally, SLUDDEN, Julieann, SIU, Lillian L, CHEN, Eric X, OZA, Amit M
Published in Clinical cancer research (01.05.2009)
Published in Clinical cancer research (01.05.2009)
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Su1374 Low Dose Azathioprine With Allopurinol Co-Therapy Without Metabolite Profiling Is More Effective and Safer Than Full Dose Azathioprine for Inflammatory Bowel Disease Patients: A Large UK Centre Experience
Stamoulos, Panagiotis, Stournaras, Evangelos, Bull, Clare, Cowan, Matthew, Mackenzie, Gary, Stenner, Jonathan, Coulthard, Sally A, Ansar, Azhar R
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
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Thiopurine methyltransferase genetics is not a major risk factor for secondary malignant neoplasms after treatment of childhood acute lymphoblastic leukemia on Berlin-Frankfurt-Münster protocols
Stanulla, Martin, Schaeffeler, Elke, Möricke, Anja, Coulthard, Sally A., Cario, Gunnar, Schrauder, André, Kaatsch, Peter, Dördelmann, Michael, Welte, Karl, Zimmermann, Martin, Reiter, Alfred, Eichelbaum, Michel, Riehm, Hansjörg, Schrappe, Martin, Schwab, Matthias
Published in Blood (13.08.2009)
Published in Blood (13.08.2009)
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Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers
Coulthard, Sally A, Redfern, Christopher P F, Vikingsson, Svante, Lindqvist-Appell, Malin, Skoglund, Karin, Jakobsen-Falk, Ingrid, Hall, Andrew G, Taylor, Gordon A, Hogarth, Linda A
Published in Molecular cancer therapeutics (01.03.2011)
Published in Molecular cancer therapeutics (01.03.2011)
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The Effect of Thiopurine Methyltransferase Expression on Sensitivity to Thiopurine Drugs
Coulthard, Sally A, Hogarth, Linda A, Little, Margaret, Matheson, Elizabeth C, Redfern, Christopher P F, Minto, Lynne, Hall, Andrew G
Published in Molecular pharmacology (01.07.2002)
Published in Molecular pharmacology (01.07.2002)
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A comparison of molecular and enzyme‐based assays for the detection of thiopurine methyltransferase mutations
Coulthard, Sally A., Rabello, Celia, Robson, Jill, Howell, Christopher, Minto, Lynne, Middleton, Peter G., Gandhi, Maher K., Jackson, Graham, McLelland, Janet, O'brien, Hugh, Smith, Stephen, Reid, Michael M., Pearson, Andrew D. J., Hall, Andrew G.
Published in British journal of haematology (01.09.2000)
Published in British journal of haematology (01.09.2000)
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Chemotherapy individualization
Veal, Gareth J, Coulthard, Sally A, Boddy, Alan V
Published in Investigational new drugs (01.05.2003)
Published in Investigational new drugs (01.05.2003)
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Molecular diagnostics: a healthcare perspective
Hall, Andrew G, Coulthard, Sally A, Irving, Julie AE
Published in Expert review of molecular diagnostics (01.01.2003)
Published in Expert review of molecular diagnostics (01.01.2003)
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