The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison
Demarquay, D, Huchet, M, Coulomb, H, Lesueur-Ginot, L, Lavergne, O, Kasprzyk, P G, Bailly, C, Camara, J, Bigg, D C
Published in Anti-cancer drugs (01.01.2001)
Published in Anti-cancer drugs (01.01.2001)
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A novel B-ring modified homocamptothecin, 12-Cl-hCPT, showing antiproliferative and topoisomerase I inhibitory activities superior to SN-38
Bailly, C, Laine, W, Baldeyrou, B, Demarquay, D, Huchet, M, Coulomb, H, Lanco, C, Lavergne, O, Bigg, D C
Published in Anti-cancer drug design (01.02.2001)
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Published in Anti-cancer drug design (01.02.2001)
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Flow cytometric monitoring of anthracycline accumulation after anti-neoplastic ether phospholipid treatment
Principe, P, Faussat-Suberville, A M, Coulomb, H, Marie, J P, Braquet, P
Published in Anti-cancer drugs (01.06.1994)
Published in Anti-cancer drugs (01.06.1994)
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Immunomodulatory activity of two new aza alkyl phospholipid antineoplastic drugs
Pignol, B, Chaumeron, S, Coulomb, H, Maisonnet, T, Vandamme, B, Broquet, C, Mencia-Huerta, J M, Braquet, P
Published in Anti-cancer drugs (01.12.1992)
Published in Anti-cancer drugs (01.12.1992)
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BN80927: A novel homocamptothecin that inhibits proliferation of human tumor cells in vitro and in vivo
DEMARQUAY, Danièle, HUCHET, Marion, COULOMB, Helène, LESUEUR-GINOT, Laurence, LAVERGNE, Olivier, CAMARA, José, KASPRZYK, Philip G, PREVOST, Grégoire, BIGG, Dennis C. H
Published in Cancer research (Chicago, Ill.) (15.07.2004)
Published in Cancer research (Chicago, Ill.) (15.07.2004)
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Topoisomerase I-Mediated Antiproliferative Activity of Enantiomerically Pure Fluorinated Homocamptothecins
Lavergne, Olivier, Demarquay, Danièle, Bailly, Christian, Lanco, Christophe, Rolland, Alain, Huchet, Marion, Coulomb, Helène, Muller, Nicole, Baroggi, Nicole, Camara, José, Le Breton, Christine, Manginot, Eric, Cazaux, Jean-Bernard, Bigg, Dennis C. H
Published in Journal of medicinal chemistry (01.06.2000)
Published in Journal of medicinal chemistry (01.06.2000)
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Homocamptothecin, an E-Ring-Modified Camptothecin Analogue, Generates New Topoisomerase I-Mediated DNA Breaks
Bailly, Christian, Lansiaux, Amélie, Dassonneville, Laurent, Demarquay, Danièle, Coulomb, Hélène, Huchet, Marion, Lavergne, Olivier, Bigg, Dennis C. H
Published in Biochemistry (Easton) (23.11.1999)
Published in Biochemistry (Easton) (23.11.1999)
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Metabolic activation of polycyclic hydrocarbons Fluorescence spectral evidence is consistent with metabolism at the 1,2- and 3,4-double bonds of 7-methylbenz[a]anthracene
Vigny, P., Duquesne, M., Coulomb, H., Lacombe, C., Tierney, B., Grover, P.L., Sims, P.
Published in FEBS letters (15.03.1977)
Published in FEBS letters (15.03.1977)
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Tumour-initiating activities of dihydrodiols of dibenz[ a,c]anthracene
Chouroulinkov, I., Coulomb, H., MacNicoll, A.D., Grover, P.L., Sims, P.
Published in Cancer letters (01.05.1983)
Published in Cancer letters (01.05.1983)
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BN 80927: A novel homocamptothecin with inhibitory activities on both topoisomerase I and topoisomerase II
Lavergne, Olivier, Harnett, Jeremiah, Rolland, Alain, Lanco, Christophe, Lesueur-Ginot, Laurence, Demarquay, Danièle, Huchet, Marion, Coulomb, Hélène, Bigg, Dennis C.H.
Published in Bioorganic & medicinal chemistry letters (06.09.1999)
Published in Bioorganic & medicinal chemistry letters (06.09.1999)
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Journal Article
The Dual Topoisomerase Inhibitor, BN 80927, Is Highly Potent against Cell Proliferation and Tumor Growth
HUCHET, MARION, DEMARQUAY, DANIÈLE, COULOMB, HÉLÈNE, KASPRZYK, PHILIP, CARLSON, MARK, LAUER, JEFFREY, La VERGNE, OLIVIER, BIGG, DENNIS
Published in Annals of the New York Academy of Sciences (01.01.2000)
Published in Annals of the New York Academy of Sciences (01.01.2000)
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The Homocamptothecin, BN 80927, Is a Potent Topoisomerase I Poison and Topoisomerase II Catalytic Inhibitor
DEMARQUAY, DANIÈLE, COULOMB, HÉLÈNE, HUCHET, MARION, LESUEUR-GINOT, LAURENCE, CAMARA, JOSÉ, LAVERGNE, OLIVIER, BIGG, DENNIS
Published in Annals of the New York Academy of Sciences (01.01.2000)
Published in Annals of the New York Academy of Sciences (01.01.2000)
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512 BN80927: a novel homocamptothecin that inhibits proliferation of human tumor cells in vitro and in vivo
Demarquay, D., Huchet, M., Coulomb, H., Lesueur-Ginot, L., Lavergne, O., Camara, J., Kaspryzk, P.G., Prevost, G., Bigg, D.C.H.
Published in European journal of cancer supplements (01.09.2004)
Published in European journal of cancer supplements (01.09.2004)
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New antineoplastic aza-phospholipids - synthesis, in-vitro cytotoxicity and differential cellular-sensitivity against 70 human tumor-cell lines
Principe, P, Broquet, C, Paull, K, Grever, M, Coulomb, H, Huchet, M, Menciahuerta, J, Braquet, P
Published in International journal of oncology (01.01.1994)
Published in International journal of oncology (01.01.1994)
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Effect of serum concentration on the cytotoxicity and sister chromatid exchange induction by a chemical carcinogen and by a diesel particulate extract in V79 hamster cells
Coulomb, Hélène M., Gu, Z.W., Loireau, Marie-Paule, Chouroulinkov, Ivan
Published in Cancer letters (01.02.1984)
Published in Cancer letters (01.02.1984)
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