The burden of trisomy 21 disrupts the proteostasis network in Down syndrome
Aivazidis, Stefanos, Coughlan, Christina M, Rauniyar, Abhishek K, Jiang, Hua, Liggett, L Alexander, Maclean, Kenneth N, Roede, James R
Published in PloS one (21.04.2017)
Published in PloS one (21.04.2017)
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Journal Article
Safety and efficacy of sargramostim (GM‐CSF) in the treatment of Alzheimer's disease
Potter, Huntington, Woodcock, Jonathan H., Boyd, Timothy D., Coughlan, Christina M., O'Shaughnessy, John R., Borges, Manuel T., Thaker, Ashesh A., Raj, Balaibail A., Adamszuk, Katarzyna, Scott, David, Adame, Vanesa, Anton, Paige, Chial, Heidi J., Gray, Helen, Daniels, Joseph, Stocker, Michelle E., Sillau, Stefan H.
Published in Alzheimer's & dementia : translational research & clinical interventions (2021)
Published in Alzheimer's & dementia : translational research & clinical interventions (2021)
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Journal Article
Mitotic defects lead to neuronal aneuploidy and apoptosis in frontotemporal lobar degeneration caused by MAPT mutations
Caneus, Julbert, Granic, Antoneta, Rademakers, Rosa, Dickson, Dennis W, Coughlan, Christina M, Chial, Heidi J, Potter, Huntington
Published in Molecular biology of the cell (01.03.2018)
Published in Molecular biology of the cell (01.03.2018)
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Journal Article
Rapid Activation of Neuroinflammation in Stroke: Plasma and Extracellular Vesicles Obtained on a Mobile Stroke Unit
Kowalski, Robert G, Ledreux, Aurélie, Violette, John E, Neumann, Robert T, Ornelas, David, Yu, Xiaoli, Griffiths, Steven G, Lewis, Scott, Nash, Priscilla, Monte, Andrew A, Coughlan, Christina M, Deighan, Clayton, Grotta, James C, Jones, William J, Graner, Michael W
Published in Stroke (1970) (01.03.2023)
Published in Stroke (1970) (01.03.2023)
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Journal Article
Varicella-Zoster Virus Infection of Primary Human Spinal Astrocytes Produces Intracellular Amylin, Amyloid-β, and an Amyloidogenic Extracellular Environment
Bubak, Andrew N, Como, Christina N, Coughlan, Christina M, Johnson, Noah R, Hassell, James E, Mescher, Teresa, Niemeyer, Christy S, Mahalingam, Ravi, Cohrs, Randall J, Boyd, Timothy D, Potter, Huntington, Russ, Holger A, Nagel, Maria A
Published in The Journal of infectious diseases (16.03.2020)
Published in The Journal of infectious diseases (16.03.2020)
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Journal Article
Degradation of Mutated Bovine Pancreatic Trypsin Inhibitor in the Yeast Vacuole Suggests Post-endoplasmic Reticulum Protein Quality Control
Coughlan, Christina M., Walker, Jennifer L., Cochran, Jared C., Wittrup, K. Dane, Brodsky, Jeffrey L.
Published in The Journal of biological chemistry (09.04.2004)
Published in The Journal of biological chemistry (09.04.2004)
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Journal Article
Amylin, Aβ42, and Amyloid in Varicella Zoster Virus Vasculopathy Cerebrospinal Fluid and Infected Vascular Cells
Bubak, Andrew N, Beseler, Cheryl, Como, Christina N, Coughlan, Christina M, Johnson, Noah R, Hassell, James E, Burnet, Anna M, Mescher, Teresa, Schmid, D Scott, Coleman, Colin, Mahalingam, Ravi, Cohrs, Randall J, Boyd, Timothy D, Potter, Huntington, Shilleh, Ali H, Russ, Holger A, Nagel, Maria A
Published in The Journal of infectious diseases (08.04.2021)
Published in The Journal of infectious diseases (08.04.2021)
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Journal Article
Proteasome activity modulates amyloid toxicity
Galvin, John, Curran, Elizabeth, Arteaga, Francisco, Goossens, Alicia, Aubuchon-Endsley, Nicki, McMurray, Michael A, Moore, Jeffrey, Hansen, Kirk C, Chial, Heidi J, Potter, Huntington, Brodsky, Jeffrey L, Coughlan, Christina M
Published in FEMS yeast research (09.03.2022)
Published in FEMS yeast research (09.03.2022)
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Journal Article
Granulocyte‐macrophage colony‐stimulating factor reverses Alzheimer’s disease pathology in the tgf344‐AD rat model
Ahmed, Md. Mahiuddin, Wang, Athena Ching‐Jung, Boyd, Timothy D., Solano, D. Adriana, Vielle, Anne, Markham, Neil, Coughlan, Christina M, Chial, Heidi J, Vergara, M. Natalia, Potter, Huntington
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
Proteomic analysis of the amyloid precursor protein fragment C99: expression in yeast
Sparvero, Louis J., Patz, Sarah, Brodsky, Jeffrey L., Coughlan, Christina M.
Published in Analytical biochemistry (15.11.2007)
Published in Analytical biochemistry (15.11.2007)
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Journal Article
Abstract 17: Ultra-early Activation Of Neuroinflammatory Cascade Following Acute Stroke: Plasma And Extracellular Vesicle Biomarkers From A Mobile Stroke Unit
Kowalski, Robert, Ledreux, Aurelie, Violette, John E, Neumann, Robert T, Grotta, James C, Ornelas, David, Yu, Xiaoli, Griffiths, Steven G, Lewis, Scott, Nash, Priscilla, Monte, Andrew A, Coughlan, Christina M, Deighan, Clayton, Jones, William J, Graner, Michael W
Published in Stroke (1970) (01.02.2023)
Published in Stroke (1970) (01.02.2023)
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Journal Article
Increased Plasma brain‐derived neurotrophic factor (BDNF) as a Biomarker for Differentiating Mild Cognitive Impairment from Cognitive Healthy: A case‐control study
Ng, Ted Kheng Siang, Coughlan, Christina M, Heyn, Patricia C, Tagawa, Alex, Carollo, James, Kua, Ee‐Heok, Mahendran, Rathi
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
Granulocyte‐Macrophage Colony‐Stimulating Factor Reduces Two Major Pathological Hallmarks of Alzheimer’s Disease and Astrogliosis in the TgF344‐AD Rat Model
Ahmed, Md. Mahiuddin, Wang, Athena Ching‐Jung, Boyd, Timothy D., Solano, D. Adriana, Vielle, Anne, Markham, Neil, Coughlan, Christina M, Chial, Heidi J, Vergara, M. Natalia, Potter, Huntington
Published in Alzheimer's & dementia (01.12.2022)
Published in Alzheimer's & dementia (01.12.2022)
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Journal Article
The immune cytokine granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) is an effective treatment for both Alzheimer’s disease and the viral diseases caused by West Nile Virus and SARS‐CoV‐2 infection, indicating that inflammation and viral infection may be partners and therapeutic co‐targets in many brain disorders
Potter, Huntington, Boyd, Timothy D., Woodcock, Jonathan H, Sillau, Stefan H, Ahmed, Md. Mahiuddin, Wang, Athena Ching‐Jung, Chial, Heidi J, Coughlan, Christina M, Kendall, Lon V., Bosco‐Lauth, Angela, Markham, Neil, Stonedahl, Sarah, Fong, Derek, Clarke, Penny, Tyler, Kenneth L.
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Inflammation and innate immune system activation in neurodegeneration, Down syndrome, aging, and infection: Therapeutic target or partner?
Potter, Huntington, Boyd, Timothy D., Ahmed, Md. Mahiuddin, Kendall, Lon V., Sillau, Stefan H, Coughlan, Christina M, Clarke, Penny, Stonedahl, Sarah, Chial, Heidi J
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
Small molecule inhibitors of apolipoprotein E4‐catalyzed amyloid‐β fibrillization as novel therapeutics for Alzheimer’s disease: Development of new models and analysis methods/screening studies/platforms
Johnson, Noah R., Wang, Athena Ching‐Jung, Coughlan, Christina M., Lucero, Esteban M., Viltz, Lisa, Allen, Cody, Markham, Neil, Chial, Heidi J., Potter, Huntington
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Small molecule inhibitors of apolipoprotein E4‐catalyzed amyloid‐β fibrillization as novel therapeutics for Alzheimer’s disease
Johnson, Noah R., Wang, Athena Ching‐Jung, Coughlan, Christina M., Lucero, Esteban M., Viltz, Lisa, Allen, Cody, Markham, Neil, Chial, Heidi J., Potter, Huntington
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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