Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma
Martell, Emma, Kuzmychova, Helgi, Kaul, Esha, Senthil, Harshal, Chowdhury, Subir Roy, Morrison, Ludivine Coudière, Fresnoza, Agnes, Zagozewski, Jamie, Venugopal, Chitra, Anderson, Chris M., Singh, Sheila K., Banerji, Versha, Werbowetski-Ogilvie, Tamra E., Sharif, Tanveer
Published in Nature communications (02.05.2023)
Published in Nature communications (02.05.2023)
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Journal Article
Embryonic Stem Cell Models of Human Brain Tumors
Morrison, Ludivine Coudière, Tatari, Nazanin, Werbowetski-Ogilvie, Tamra E
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2019)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2019)
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Journal Article
Differential cellular responses induced by dorsomorphin and LDN‐193189 in chemotherapy‐sensitive and chemotherapy‐resistant human epithelial ovarian cancer cells
Ali, Jennifer L., Lagasse, Brittany J., Minuk, Ainsley J., Love, Allison J., Moraya, Amani I., Lam, Linda, Arthur, Gilbert, Gibson, Spencer B., Morrison, Ludivine Coudière, Werbowetski‐Ogilvie, Tamra E., Fu, Yangxin, Nachtigal, Mark W.
Published in International journal of cancer (01.03.2015)
Published in International journal of cancer (01.03.2015)
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Journal Article
In Vivo Generation of Neural Tumors from Neoplastic Pluripotent Stem Cells Models Early Human Pediatric Brain Tumor Formation
Werbowetski-Ogilvie, Tamra E., Morrison, Ludivine Coudière, Fiebig-Comyn, Aline, Bhatia, Mickie
Published in Stem cells (Dayton, Ohio) (01.03.2012)
Published in Stem cells (Dayton, Ohio) (01.03.2012)
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Journal Article
Deconstruction of Medulloblastoma Cellular Heterogeneity Reveals Differences between the Most Highly Invasive and Self-Renewing Phenotypes
Coudière Morrison, Ludivine, McClelland, Robyn, Aiken, Christopher, Bridges, Melissa, Liang, Lisa, Wang, Xin, Di Curzio, Domenico, Del Bigio, Marc R, Taylor, Michael D, Werbowetski-Ogilvie, Tamra E
Published in Neoplasia (New York, N.Y.) (01.04.2013)
Published in Neoplasia (New York, N.Y.) (01.04.2013)
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Journal Article
Characterization of a novel OTX2‐driven stem cell program in Group 3 and Group 4 medulloblastoma
Stromecki, Margaret, Tatari, Nazanin, Morrison, Ludivine Coudière, Kaur, Ravinder, Zagozewski, Jamie, Palidwor, Gareth, Ramaswamy, Vijay, Skowron, Patryk, Wölfl, Matthias, Milde, Till, Del Bigio, Marc R., Taylor, Michael D., Werbowetski‐Ogilvie, Tamra E.
Published in Molecular oncology (01.04.2018)
Published in Molecular oncology (01.04.2018)
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Journal Article
Characterization of novel biomarkers in selecting for subtype specific medulloblastoma phenotypes
Liang, Lisa, Aiken, Christopher, McClelland, Robyn, Morrison, Ludivine Coudière, Tatari, Nazanin, Remke, Marc, Ramaswamy, Vijay, Issaivanan, Magimairajan, Ryken, Timothy, Del Bigio, Marc R, Taylor, Michael D, Werbowetski-Ogilvie, Tamra E
Published in Oncotarget (17.11.2015)
Published in Oncotarget (17.11.2015)
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Journal Article
OTX2 exhibits cell-context-dependent effects on cellular and molecular properties of human embryonic neural precursors and medulloblastoma cells
Kaur, Ravinder, Aiken, Christopher, Morrison, Ludivine Coudière, Rao, Radhika, Del Bigio, Marc R, Rampalli, Shravanti, Werbowetski-Ogilvie, Tamra
Published in Disease models & mechanisms (01.10.2015)
Published in Disease models & mechanisms (01.10.2015)
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Journal Article
Novel glycolipid agents for killing cisplatin-resistant human epithelial ovarian cancer cells
Moraya, Amani I, Ali, Jennifer L, Samadder, Pranati, Liang, Lisa, Morrison, Ludivine Coudière, Werbowetski-Ogilvie, Tamra E, Ogunsina, Makanjuola, Schweizer, Frank, Arthur, Gilbert, Nachtigal, Mark W
Published in Journal of experimental & clinical cancer research (12.05.2017)
Published in Journal of experimental & clinical cancer research (12.05.2017)
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Journal Article
An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate
Zagozewski, Jamie, Shahriary, Ghazaleh M., Morrison, Ludivine Coudière, Saulnier, Olivier, Stromecki, Margaret, Fresnoza, Agnes, Palidwor, Gareth, Porter, Christopher J., Forget, Antoine, Ayrault, Olivier, Hawkins, Cynthia, Chan, Jennifer A., Vladoiu, Maria C., Sundaresan, Lakshmikirupa, Arsenio, Janilyn, Taylor, Michael D., Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra E.
Published in Nature communications (20.07.2020)
Published in Nature communications (20.07.2020)
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Journal Article
Cross-species analysis of SHH medulloblastoma models reveals significant inhibitory effects of trametinib on tumor progression
Borlase, Stephanie, DeCarlo, Alexandria, Coudière-Morrison, Ludivine, Liang, Lisa, Porter, Christopher J., Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra E.
Published in Cell death discovery (19.09.2023)
Published in Cell death discovery (19.09.2023)
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Journal Article
Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression
Zagozewski, Jamie, Borlase, Stephanie, Guppy, Brent J., Coudière-Morrison, Ludivine, Shahriary, Ghazaleh M., Gordon, Victor, Liang, Lisa, Cheng, Stephen, Porter, Christopher J., Kelley, Rhonda, Hawkins, Cynthia, Chan, Jennifer A., Liang, Yan, Gong, Jingjing, Nör, Carolina, Saulnier, Olivier, Wechsler-Reya, Robert J., Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra E.
Published in Communications biology (14.07.2022)
Published in Communications biology (14.07.2022)
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Journal Article
A group 3 medulloblastoma stem cell program is maintained by OTX2-mediated alternative splicing
Saulnier, Olivier, Zagozewski, Jamie, Liang, Lisa, Hendrikse, Liam D., Layug, Paul, Gordon, Victor, Aldinger, Kimberly A., Haldipur, Parthiv, Borlase, Stephanie, Coudière-Morrison, Ludivine, Cai, Ting, Martell, Emma, Gonzales, Naomi M., Palidwor, Gareth, Porter, Christopher J., Richard, Stéphane, Sharif, Tanveer, Millen, Kathleen J., Doble, Brad W., Taylor, Michael D., Werbowetski-Ogilvie, Tamra E.
Published in Nature cell biology (01.08.2024)
Published in Nature cell biology (01.08.2024)
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Journal Article
CD271 + Cells Are Diagnostic and Prognostic and Exhibit Elevated MAPK Activity in SHH Medulloblastoma
Liang, Lisa, Coudière-Morrison, Ludivine, Tatari, Nazanin, Stromecki, Margaret, Fresnoza, Agnes, Porter, Christopher J, Del Bigio, Marc R, Hawkins, Cynthia, Chan, Jennifer A, Ryken, Timothy C, Taylor, Michael D, Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra E
Published in Cancer research (Chicago, Ill.) (15.08.2018)
Published in Cancer research (Chicago, Ill.) (15.08.2018)
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Journal Article
MDB-06. ALTERNATIVE SPLICING MEDIATED BY OTX2 DRIVES THE DEVELOPMENT OF GROUP 3 MEDULLOBLASTOMA
Saulnier, Olivier, Zagozewski, Jamie, Liang, Lisa, Hendrikse, Liam D, Layug, Paul, Gordon, Victor, Aldinger, Kimberly A, Haldipur, Parthiv, Borlase, Stephanie, Coudière-Morrison, Ludivine, Cai, Ting, Martell, Emma, Palidwor, Gareth, Porter, Christopher J, Richard, Stephane, Sharif, Tanveer, Doble, Brad W, Millen, Kathleen J, Taylor, Michael D, Werbowetski-Ogilvie, Tamra E
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
Published in Neuro-oncology (Charlottesville, Va.) (18.06.2024)
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Journal Article
15 CD271/p75NTR is a novel diagnostic marker, prognostic indicator and therapeutic target for SHH medulloblastoma
Liang, L., Morrison, Ludivine Coudière, Tatari, Nazanin, Stromecki, Margaret, Fresnoza, Agnes, Porter, Christopher J., Del Bigio, Marc R., Chan, Cynthia Hawkins Jennifer, Taylor, Michael D., Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra
Published in Canadian journal of neurological sciences (01.06.2018)
Published in Canadian journal of neurological sciences (01.06.2018)
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Journal Article
Characterization of a novel OTX 2‐driven stem cell program in Group 3 and Group 4 medulloblastoma
Stromecki, Margaret, Tatari, Nazanin, Morrison, Ludivine Coudière, Kaur, Ravinder, Zagozewski, Jamie, Palidwor, Gareth, Ramaswamy, Vijay, Skowron, Patryk, Wölfl, Matthias, Milde, Till, Del Bigio, Marc R., Taylor, Michael D., Werbowetski‐Ogilvie, Tamra E.
Published in Molecular oncology (01.04.2018)
Published in Molecular oncology (01.04.2018)
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Journal Article
Deconstruction of Medulloblastoma Cellular Heterogeneity Reveals Differences between the Most Highly Invasive and Self-Renewing Phenotypes12
Morrison, Ludivine Coudière, McClelland, Robyn, Aiken, Christopher, Bridges, Melissa, Liang, Lisa, Wang, Xin, Di Curzio, Domenico, Del Bigio, Marc R, Taylor, Michael D, Werbowetski-Ogilvie, Tamra E
Published in Neoplasia (New York, N.Y.) (01.04.2013)
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Published in Neoplasia (New York, N.Y.) (01.04.2013)
Journal Article
MDB-21. THE OTX2-REGULATED ALTERNATIVE SPLICING LANDSCAPE CONTROLS DIFFERENTIATION AND RECONSTITUTES THE DEVELOPMENTAL ORIGINS OF GROUP 3 MEDULLOBLASTOMA
Saulnier, Olivier, Zagozewski, Jamie, Liang, Lisa, Hendrikse, Liam D, Gordon, Victor, Aldinger, Kimberly A, Haldipur, Parthiv, Borlase, Stephanie, Coudiere-Morrison, Ludivine, Layug, Paul, Cai, Ting, Porter, Christopher J, Richard, Stephane, Doble, Brad W, Millen, Kathleen J, Taylor, Michael D, Werbowetski-Ogilvie, Tamra E
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
Published in Neuro-oncology (Charlottesville, Va.) (12.06.2023)
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Journal Article
MEDU-12. CD271 (P75NTR) AS A NOVEL DIAGNOSTIC MARKER AND THERAPEUTIC TARGET FOR SHH MEDULLOBLASTOMA
Liang, Lisa, Coudiere-Morrison, Ludivine, Tatari, Nazanin, Ramaswamy, Vijay, Ryken, Timothy, Bigio, Marc Del, Hawkins, Cynthia, Chan, Jennifer, Werbowetski-Ogilvie, Tamra
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
Published in Neuro-oncology (Charlottesville, Va.) (01.06.2017)
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