알파-1-항트립신 결핍증(AATD) 치료를 위한 알파-1-항트립신 조절제로서의 피롤로[2,3-F]인다졸 유도체 및 2,4,5,10-테트라아자트리시클로[7.3.0.03,7]도데카-1,3,5,8,11-펜타엔 유도체
BRODNEY MICHAEL AARON, HALL AMY B, FIMOGNARI JR. ROBERT FRANCIS, ZAKY MARIAM, NUHANT PHILIPPE MARCEL, JONES PETER, COTTRELL KEVIN MICHAEL, FANNING LEV T. D, HURLEY DENNIS JAMES, KESAVAN SARATHY, JOHNSON JR. MAC ARTHUR, GARCIA BARRANTES PEDRO MANUEL, XU JINWANG, TAPLEY TIMOTHY LEWIS, BOYD MICHAEL JOHN, THOMSON STEPHEN A, SWETT REBECCA JANE, DAMAGNEZ VERONIQUE, BOUCHER DIANE MARIE, MAXWELL JOHN PATRICK, GIROUX SIMON, GREY JR. RONALD LEE
Year of Publication 09.12.2022
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Year of Publication 09.12.2022
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알파-1-항트립신 결핍증(AATD)의 치료를 위한 알파-1-항트립신 조절제로서의 인돌 유도체
HALL AMY B, FIMOGNARI JR. ROBERT FRANCIS, TANG QING, HURLEY DENNIS JAMES, JOHNSON JR. MAC ARTHUR, BANDARAGE UPUL KEERTHI, TAPLEY TIMOTHY LEWIS, BOYD MICHAEL JOHN, ZHANG HU, DAMAGNEZ VERONIQUE, CLARK MICHAEL PHILIP, DEININGER DAVID D, MAXWELL JOHN PATRICK, BRODNEY MICHAEL AARON, NUHANT PHILIPPE MARCEL, ZAKY MARIAM, RONKIN STEVEN M, JONES PETER, COTTRELL KEVIN MICHAEL, COLLIER PHILIP NOEL, WAAL NATHAN D, FLEMING GABRIELLE SIMONE, MAXWELL BRAD, FANNING LEV T.D, ALLEN EMILY ELIZABETH, DENG HONGBO, WANG JIAN, THOMSON STEPHEN A, SWETT REBECCA JANE, BOUCHER DIANE MARIE, GIROUX SIMON
Year of Publication 14.12.2022
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Year of Publication 14.12.2022
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알파-1 항트립신 조절인자로서 축합된 트리시클릭 피롤
GUIDO SAMANTHA, ROEPER STEFANIE, TANG QING, GAGNON KEVIN JAMES, BOUCHER DIANE, HALL AMY BETH, HURLEY DENNIS JAMES, SHI YI, KESAVAN SARATHY, LIU SIYING, JOHNSON JR. MAC ARTHUR, RODAY SETU, BANDARAGE UPUL KEERTHI, LAI MEI HSIU, HOOD SARAH CAROL, TAPLEY TIMOTHY LEWIS, FANNING LEV TYLER DEWEY, BOYD MICHAEL JOHN, DAMAGNEZ VERONIQUE, CLARK MICHAEL PHILIP, MAXWELL JOHN PATRICK, THOMSON STEPHEN, BLIGH CAVAN MCKEON, GIACOMETTI ROBERT DANIEL, BRODNEY MICHAEL AARON, JONES PETER, NUHANT PHILIPPE MARCEL, RONKIN STEVEN M, ZAKY MARIAM, COTTRELL KEVIN MICHAEL, FLEMING GABRIELLE SIMONE, STAVROPOULOS KATHY, MAXWELL BRAD, SAWANT RUPA, MEDEK ALES, GARCIA BARRANTES PEDRO MANUEL, SHRESTHA MUNA, XU JINWANG, OVERHOFF KIRK ALAN, SPOSATO MARISA, FIMOGNARI ROBERT FRANCIS, LOOKER ADAM, SWETT REBECCA JANE, GIROUX SIMON, GREY JR. RONALD LEE
Year of Publication 03.03.2022
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Year of Publication 03.03.2022
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알파-1 항트립신 조절제
ROEPER STEFANIE, BOUCHER DIANE M, GARCIA BARRANTES PEDRO M, TANG QING, FIMOGNARI JR. ROBERT FRANCIS, GAGNON KEVIN JAMES, DEWEY FANNING LEV TYLER, HUSSEY JOSHUA KENNEDY, SHI YI, HALL AMY BETH, HURLEY DENNIS JAMES, KESAVAN SARATHY, JOHNSON JR. MAC ARTHUR, RODAY SETU, MAXWELL BRAD D, BANDARAGE UPUL KEERTHI, ECCLES MARY ELIZABETH, HOOD SARAH CAROL, TAPLEY TIMOTHY LEWIS, BOYD MICHAEL JOHN, DAMAGNEZ VERONIQUE, WALDO MICHAEL, MAXWELL JOHN PATRICK, BLIGH CAVAN MCKEON, BRODNEY MICHAEL AARON, JONES PETER, NUHANT PHILIPPE MARCEL, COTTRELL KEVIN MICHAEL, SAWANT RUPA, MEDEK ALES, XU JINWANG, LOOKER ADAM, NAVAMAL METTACHIT, THOMSON STEPHEN A, SWETT REBECCA JANE, GIROUX SIMON, GREY JR. RONALD LEE
Year of Publication 16.07.2021
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Year of Publication 16.07.2021
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DNA-PK INHIBITORS
LEDEBOER MARK WILLEM, COTTRELL KEVIN MICHAEL, KENNEDY JOSEPH M, WAAL NATHAN D, LI PAN, DENG HONGBO, XU JINWANG, PIERCE ALBERT CHARLES, LAUFFER DAVID J, GREEN JEREMY, GAO HUAI, MORRIS MARK A, DUFFY JOHN P, CHARIFSON PAUL S, MAXWELL JOHN PATRICK, JACKSON KATRINA LEE, GIROUX SIMON
Year of Publication 14.01.2015
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Year of Publication 14.01.2015
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DNA-PK inhibitors
Jackson, Katrina Lee, Maxwell, John Patrick, Li, Pan, Gu, Wenxin, Ronkin, Steven M, Deng, Hongbo, Court, John J, Morris, Mark A, Charifson, Paul S, Giroux, Simon, Xu, Jinwang, Pierce, Albert Charles, Cottrell, Kevin Michael, Tang, Qing, Lauffer, David J, Waal, Nathan D
Year of Publication 14.11.2023
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Year of Publication 14.11.2023
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SUBSTITUTED QUINOXALINE DNA-PK INHIBITORS
Jackson, Katrina Lee, Maxwell, John Patrick, Li, Pan, Gu, Wenxin, Ronkin, Steven M, Deng, Hongbo, Court, John J, Morris, Mark A, Charifson, Paul S, Giroux, Simon, Xu, Jinwang, Pierce, Albert Charles, Cottrell, Kevin Michael, Tang, Qing, Lauffer, David J, Waal, Nathan D
Year of Publication 07.09.2023
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Year of Publication 07.09.2023
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PYRANO[4,3-B]INDOLE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, HURLEY, Dennis James, GU, Wenxin, BOUCHER, Diane Marie, CLARK, Michael Philip, FANNING, Lev T.D, MAXWELL, John Patrick, JOHNSON, JR., Mac Arthur, DAMAGNEZ, Veronique, KESAVAN, Sarathy, JONES, Peter, TAPLEY, Timothy Lewis, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, WAAL, Nathan D, COLLIER, Philip Noel, TANG, Qing
Year of Publication 25.05.2023
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Year of Publication 25.05.2023
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PYRROLO[2,3-F]INDAZOLE AND 2,4,5,10-TETRAZATRICYCLO[7.3.0.03,7]DODECA-1,3(7),5,8,11-PENTAENE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, GREY, Jr., Ronald Lee, HURLEY, Dennis James, BOUCHER, Diane Marie, FIMOGNARI, Jr., Robert Francis, FANNING, Lev T.D, MAXWELL, John Patrick, XU, Jinwang, DAMAGNEZ, Veronique, KESAVAN, Sarathy, JOHNSON, Jr., Mac Arthur, JONES, Peter, TAPLEY, Timothy Lewis, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, NUHANT, Philippe Marcel
Year of Publication 25.05.2023
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Year of Publication 25.05.2023
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7- OR 8-HYDROXY-ISOQUINOLINE AND 7- OR 8-HYDROXY-QUINOLINE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, SENTER, Timothy J, HURLEY, Dennis James, GU, Wenxin, BOUCHER, Diane Marie, CLARK, Michael Philip, FANNING, Lev T.D, MAXWELL, John Patrick, DAMAGNEZ, Veronique, STONE, Steven David, JOHNSON, Jr., Mac Arthur, JONES, Peter, TAPLEY, Timothy Lewis, DENINNO, Michael Paul, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, GALE-DAY, Zachary, TANG, Qing
Year of Publication 25.05.2023
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Year of Publication 25.05.2023
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MODULATORS OF ALPHA-1 ANTITRYPSIN
GAGNON, Kevin James, COTTRELL, Kevin Michael, LOOKER, Adam, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, FLEMING, Gabrielle Simone, RODAY, Setu, GIACOMETTI, Robert Daniel, FANNING, Lev Tyler Dewey, JOHNSON, JR., Mac Arthur, RONKIN, Steven M, STAVROPOULOS, Kathy, KESAVAN, Sarathy, THOMSON, Stephen, GREY, JR., Ronald Lee, SAWANT, Rupa, GUIDO, Samantha, HOOD, Sarah Carol, SWETT, Rebecca Jane, NUHANT, Philippe Marcel, SHI, Yi, SHRESTHA, Muna, MAXWELL, Brad, BOUCHER, Diane, SPOSATO, Marisa, BRODNEY, Michael Aaron, MEDEK, Ales, BLIGH, Cavan McKeon, OVERHOFF, Kirk Alan, HURLEY, Dennis James, CLARK, Michael Philip, MAXWELL, John Patrick, DAMAGNEZ, Veronique, XU, Jinwang, FIMOGNARI, Robert Francis, LAI, Mei-Hsiu, BANDARAGE, Upul Keerthi, HALL, Amy Beth, TAPLEY, Timothy Lewis, ROEPER, Stefanie, Jones, Peter, LIU, Siying, GIROUX, Simon, TANG, Qing
Year of Publication 10.10.2024
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Year of Publication 10.10.2024
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Modulators of alpha-1 antitrypsin
Gagnon, Kevin James, Overhoff, Kirk Alan, Damagnez, Veronique, Hood, Sarah Carol, Johnson, Jr., Mac Arthur, Ronkin, Steven M, Garcia Barrantes, Pedro Manuel, Bligh, Cavan McKeon, Fleming, Gabrielle Simone, Giroux, Simon, Thomson, Stephen, Giacometti, Robert Daniel, Grey, Jr., Ronald Lee, Liu, Siying, Sposato, Marisa, Zaky, Mariam, Cottrell, Kevin Michael, Tang, Qing, Lai, Mei-Hsiu, Sawant, Rupa, Fanning, Lev Tyler Dewey, Kesavan, Sarathy, Stavropoulos, Kathy, Medek, Ales, Maxwell, Brad, Shi, Yi, Brodney, Michael Aaron, Maxwell, John Patrick, Nuhant, Philippe Marcel, Tapley, Timothy Lewis, Hurley, Dennis James, Boyd, Michael John, Hall, Amy Beth, Roday, Setu, Fimognari, Robert Francis, Xu, Jinwang, Clark, Michael Philip, Looker, Adam, Boucher, Diane, Guido, Samantha, Jones, Peter, Bandarage, Upul Keerthi, Shrestha, Muna, Swett, Rebecca Jane, Roeper, Stefanie
Year of Publication 30.01.2024
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Year of Publication 30.01.2024
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PYRANO[4,3-B]L NDOLE DERIVATIVES AS ALPHA-1 -ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1 -ANTITRYPSIN DEFICIENCY (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, HURLEY, Dennis James, GU, Wenxin, BOUCHER, Diane Marie, CLARK, Michael Philip, FANNING, Lev T.D, MAXWELL, John Patrick, JOHNSON, JR., Mac Arthur, DAMAGNEZ, Veronique, KESAVAN, Sarathy, JONES, Peter, TAPLEY, Timothy Lewis, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, WAAL, Nathan D, COLLIER, Philip Noel, TANG, Qing
Year of Publication 08.02.2023
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Year of Publication 08.02.2023
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7- OR 8-HYDROXY-ISOQUINOLINE AND 7- OR 8-HYDROXY-QUINOLINE DERIVATIVES AS ALPHA-1 -ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1 -ANTITRYPSIN DEFICIENCY (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, SENTER, Timothy J, HURLEY, Dennis James, GU, Wenxin, BOUCHER, Diane Marie, CLARK, Michael Philip, FANNING, Lev T.D, MAXWELL, John Patrick, JOHNSON, JR., Mac Arthur, DAMAGNEZ, Veronique, STONE, Steven David, JONES, Peter, TAPLEY, Timothy Lewis, DENINNO, Michael Paul, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, GALE-DAY, Zachary, TANG, Qing
Year of Publication 08.02.2023
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Year of Publication 08.02.2023
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1H-PYRAZOLO[4,3-G]ISOQUINOLINE AND 1H-PYRAZOLO[4,3-G]QUINOLINE DERIVATIVES AS ALPHA-1-ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1-ANTITRYPSIN DEFICIENCY (AATD)
ZHANG, Hu, HALL, Amy B, COTTRELL, Kevin Michael, GARCIA BARRANTES, Pedro Manuel, HURLEY, Dennis James, GU, Wenxin, BOUCHER, Diane Marie, FANNING, Lev T.D, MAXWELL, John Patrick, XU, Jinwang, DAMAGNEZ, Veronique, KARNS, Alexander S, BANDARAGE, Upul Keerthi, JOHNSON, Jr., Mac Arthur, TAPLEY, Timothy Lewis, DENINNO, Michael Paul, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, GALE-DAY, Zachary, ALLEN, Emily Elizabeth, NUHANT, Philippe Marcel, LIAO, Yusheng, TANG, Qing
Year of Publication 25.05.2023
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Year of Publication 25.05.2023
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MODULATORS OF ALPHA-1 ANTITRYPSIN
MESSERSMITH, David, HALL, Amy B, COTTRELL, Kevin Michael, BOYD, Michael John, FLEMING, Gabrielle Simone, FANNING, Lev T.D, RONKIN, Steven M, WANG, Jian, MORRIS, Mark A, KESAVAN, Sarathy, JONES, Peter, SWETT, Rebecca Jane, NUHANT, Philippe Marcel, WAAL, Nathan D, COLLIER, Philip Noel, BRODNEY, Michael Aaron, HURLEY, Dennis James, BOUCHER, Diane Marie, CLARK, Michael Philip, MAXWELL, John Patrick, XU, Jinwang, DAMAGNEZ, Veronique, BANDARAGE, Upul Keerthi, JOHNSON, Jr., Mac Arthur, DENG, Hongbo, TAPLEY, Timothy Lewis, THOMSON, Stephen A, GIROUX, Simon, TANG, Qing, DANIEL, Kevin Brett
Year of Publication 26.10.2023
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Year of Publication 26.10.2023
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7- or 8-hydroxy-isoquinoline and 7- or 8-hydroxy-quinoline derivatives as alpha-1 -antitrypsin modulators for treating alpha-1 -antitrypsin deficiency (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, SENTER, Timothy J, JOHNSON, JR, HURLEY, Dennis James, GU, Wenxin, BOUCHER, Diane Marie, CLARK, Michael Philip, FANNING, Lev T.D, MAXWELL, John Patrick, DAMAGNEZ, Veronique, STONE, Steven David, JONES, Peter, TAPLEY, Timothy Lewis, DENINNO, Michael Paul, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, GALE-DAY, Zachary, TANG, Qing
Year of Publication 27.10.2022
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Year of Publication 27.10.2022
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Pyrrolo(2,3-f)indazole and 2,4,5,10-tetrazatricyclo(7.3.0.03,7)dodeca-1,3(7),5,8,11-pentaene derivatives as alpha-1-antitrypsin modulators for treating alpha-1-antitrypsin deficiency (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, BOYD, Michael John, ZAKY, Mariam, GARCIA BARRANTES, Pedro Manuel, GREY Jr., Ronald Lee, HURLEY, Dennis James, BOUCHER, Diane Marie, MAXWELL, John Patrick, XU, Jinwang, DAMAGNEZ, Veronique, KESAVAN, Sarathy, JONES, Peter, TAPLEY, Timothy Lewis, JOHNSON, Jr, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, FANNING, Lev T. D, NUHANT, Philippe Marcel, FIMOGNARI Jr., Robert Francis
Year of Publication 27.10.2022
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Year of Publication 27.10.2022
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Pyrano(4,3-b)l ndole derivatives as alpha-1 -antitrypsin modulators for treating alpha-1 -antitrypsin deficiency (AATD)
HALL, Amy B, COTTRELL, Kevin Michael, BRODNEY, Michael Aaron, JOHNSON, JR, HURLEY, Dennis James, GU, Wenxin, BOUCHER, Diane Marie, CLARK, Michael Philip, FANNING, Lev T.D, MAXWELL, John Patrick, DAMAGNEZ, Veronique, KESAVAN, Sarathy, JONES, Peter, TAPLEY, Timothy Lewis, THOMSON, Stephen A, SWETT, Rebecca Jane, GIROUX, Simon, WAAL, Nathan D, COLLIER, Philip Noel, TANG, Qing
Year of Publication 27.10.2022
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Year of Publication 27.10.2022
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